Search filters

List of works by David Gadsby

CFTR channel gating: incremental progress in irreversible steps.

scientific article

CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains

scientific article published on February 2005

Charge Translocation by the Na/K Pumpa ⬇️

scientific article published on November 3, 1997

Chloride conductance regulated by cyclic AMP-dependent protein kinase in cardiac myocytes

scientific article published in Nature

Cysteine accessibility probes timing and extent of NBD separation along the dimer interface in gating CFTR channels

scientific article

Direct measurement of changes in sodium pump current in canine cardiac Purkinje fibers ⬇️

scientific article published on April 1, 1979

Distinct Mg(2+)-dependent steps rate limit opening and closing of a single CFTR Cl(-) channel

scientific article

Electrogenic sodium extrusion can stop triggered activity in the canine coronary sinus

scientific article published on 01 October 1981

Electrogenic sodium extrusion in cardiac Purkinje fibers ⬇️

scientific article published on June 1, 1979

Electrophysiological, biochemical, and bioinformatic methods for studying CFTR channel gating and its regulation

scientific article published in January 2011

Energetics of the Reactions Controlling the Deeply Occluded State of the Na+/K+ Pump

Energy landscape of the reactions governing the Na+ deeply occluded state of the Na+/K+-ATPase in the giant axon of the Humboldt squid

scientific article published on 5 December 2011

Extracellular Access to the Na,K Pump: Pathway Similar to Ion Channel ⬇️

scientific article published on 01 April 1993

Functional roles of nonconserved structural segments in CFTR's NH2-terminal nucleotide binding domain

scientific article

Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump.

scientific article

In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimer

scientific article published on 12 October 2006

Introduction. The blurred boundary between channels and transporters

scientific article published in January 2009

Ion channel-like properties of the Na+/K+ Pump

scientific article

Ion channels versus ion pumps: the principal difference, in principle

scientific article published on 02 April 2009

Ion occlusion/deocclusion partial reactions in individual palytoxin-modified Na/K pumps

scientific article

Ion permeation through the Na+,K+-ATPase

scientific article published in Nature

Ion transport: spot the difference

scientific article published in February 2004

Large diameter of palytoxin-induced Na/K pump channels and modulation of palytoxin interaction by Na/K pump ligands

scientific article published on 15 March 2004

Molecular Structure of the Human CFTR Ion Channel.

scientific article published on March 2017

Na+/K+-pump ligands modulate gating of palytoxin-induced ion channels

scholarly article

Noradrenaline hyperpolarizes cells of the canine coronary sinus by increasing their permeability to potassium ions

scientific article published on 01 June 1983

On the mechanism of MgATP-dependent gating of CFTR Cl- channels

scientific article

Ouabain affinity determining residues lie close to the Na/K pump ion pathway

scholarly article

Overview: stoichiometry and voltage dependence of the Na/K pump

scientific article

Paul F. Cranefield, M.D., Ph.D. April 28, 1925 to May 31, 2003.

scientific article published in July 2003

Preferential phosphorylation of R-domain Serine 768 dampens activation of CFTR channels by PKA.

scientific article

Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating ⬇️

scientific article

Review. Peering into an ATPase ion pump with single-channel recordings.

scientific article published on January 2009

Route, mechanism, and implications of proton import during Na+/K+ exchange by native Na+/K+-ATPase pumps

scientific article published on April 2014

STRUCTURE, GATING, AND REGULATION OF THE CFTR ANION CHANNEL

scientific article published on 01 January 2019

Single ion occupancy and steady-state gating of Na channels in squid giant axon

scientific article

Sodium flux ratio in Na/K pump-channels opened by palytoxin

scientific article

Stoichiometry and voltage dependence of the sodium pump in voltage-clamped, internally dialyzed squid giant axon

scientific article

Strict coupling between CFTR's catalytic cycle and gating of its Cl- ion pore revealed by distributions of open channel burst durations.

scientific article

Structural biology: Ion pumps made crystal clear

scientific article published in Nature

The ABC protein turned chloride channel whose failure causes cystic fibrosis

scientific article

The basis for the membrane potential of quiescent cells of the canine coronary sinus

scientific article published in June 1983

The dynamic relationships between the three events that release individual Na+ ions from the Na+/K+-ATPase ⬇️

scientific article published on February 14, 2012

The effects of acetylcholine on the electrical activity of canine cardiac Purkinje fibers

scientific article published on 01 July 1978

The ion pathway through the opened Na(+),K(+)-ATPase pump

scientific article

The protein kinase A-regulated cardiac Cl- channel resembles the cystic fibrosis transmembrane conductance regulator

scientific article published on November 5, 1992

The two C-terminal tyrosines stabilize occluded Na/K pump conformations containing Na or K ions

scientific article

Thermodynamics of CFTR channel gating: a spreading conformational change initiates an irreversible gating cycle

scientific article

Three distinct and sequential steps in the release of sodium ions by the Na+/K+-ATPase

scientific article

Two levels of resting potential in cardiac Purkinje fibers ⬇️

scientific article published on December 1, 1977

Visualizing the mapped ion pathway through the Na,K-ATPase pump

scientific article

Voltage dependence of the Na-K pump

scientific article published on January 1988

Voltage dependence of the Na/K pump

scientific article published on January 1997

Voltage dependence of the apparent affinity for external Na(+) of the backward-running sodium pump

scientific article

Paulina is supported by:

About Paulina

Help