List of works - Pål Kristian Selbo

177Lu-DOTA-HH1, a novel anti-CD37 radio-immunoconjugate: a study of toxicity in nude mice.

scientific article

5-Aminolevulinic acid-based photochemical internalization of the immunotoxin MOC31-gelonin generates synergistic cytotoxic effects in vitro

scientific article

5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin.

scientific article published on 19 December 2017

Abstracts from the 4th ImmunoTherapy of Cancer Conference: Prague, Czech Republic. 20–22 March 2017.

scientific article

Circumvention of resistance to photodynamic therapy in doxorubicin-resistant sarcoma by photochemical internalization of gelonin

scientific article published on 26 September 2013

Design, Characterization, and Evaluation of scFvCD133/rGelonin: A CD133-Targeting Recombinant Immunotoxin for Use in Combination with Photochemical Internalization

scientific article published on 26 December 2019

Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance.

scientific article

Disulfonated tetraphenyl chlorin (TPCS2a), a novel photosensitizer developed for clinical utilization of photochemical internalization.

scientific article

Enhanced photodynamic destruction of a transplantable fibrosarcoma using photochemical internalisation of gelonin

scientific article published on June 2005

Enhanced targeting of triple-negative breast carcinoma and malignant melanoma by photochemical internalization of CSPG4-targeting immunotoxins.

scientific article published on 22 March 2018

Epidermal growth factor receptor-targeted photosensitizer selectively inhibits EGFR signaling and induces targeted phototoxicity in ovarian cancer cells

scientific article

Evaluation of the binding of radiolabeled rituximab to CD20-positive lymphoma cells: an in vitro feasibility study concerning low-dose-rate radioimmunotherapy with the alpha-emitter 227Th

scientific article published on August 2007

Extracellular phospholipase A2 expression in sarcoidosis

scientific article published on 01 March 1996

High aldehyde dehydrogenase activity does not protect colon cancer cells against TPCS2a-sensitized photokilling

scientific article published on 28 February 2020

In vivo documentation of photochemical internalization, a novel approach to site specific cancer therapy

Intracellular re-localisation by photochemical internalisation enhances the cytotoxic effect of gelonin--quantitative studies in normal rat liver.

scientific article

Intradermal photosensitisation facilitates stimulation of MHC class-I restricted CD8 T-cell responses of co-administered antigen

scientific article published on 23 November 2013

Light directed gene transfer by photochemical internalisation.

scientific article

Light-controlled endosomal escape of the novel CD133-targeting immunotoxin AC133-saporin by photochemical internalization - A minimally invasive cancer stem cell-targeting strategy.

scientific article published on 7 March 2015

Light-triggered, efficient cytosolic release of IM7-saporin targeting the putative cancer stem cell marker CD44 by photochemical internalization.

scientific article

Mechanistic investigation and implications of photodynamic therapy induction of vascular endothelial growth factor in prostate cancer.

scientific article published on June 2006

Multi-modality therapeutics with potent anti-tumor effects: photochemical internalization enhances delivery of the fusion toxin scFvMEL/rGel

scientific article

Photochemical Internalization for Intracellular Drug Delivery. From Basic Mechanisms to Clinical Research

scientific article published on 14 February 2020

Photochemical Internalization of Peptide Antigens Provides a Novel Strategy to Realize Therapeutic Cancer Vaccination

scientific article published on 4 April 2018

Photochemical Internalization: Light Paves Way for New Cancer Chemotherapies and Vaccines

scientific article published on 09 January 2020

Photochemical activation of drugs for the treatment of therapy-resistant cancers

scientific article published on 07 April 2015

Photochemical disruption of endocytic vesicles before delivery of drugs: a new strategy for cancer therapy.

scientific article

Photochemical drug and gene delivery

scientific article published in June 2004

Photochemical internalisation (PCI): a further development of photodynamic therapy for the treatment of skin cancer

scientific article published on November 2010

Photochemical internalisation in drug and gene delivery.

scientific article published on January 2004

Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin

scientific article published on 01 September 2000

Photochemical internalisation, a minimally invasive strategy for light-controlled endosomal escape of cancer stem cell-targeting therapeutics.

scientific article published on 25 March 2015

Photochemical internalisation: a novel drug delivery system

scientific article

Photochemical internalization (PCI) in cancer therapy: from bench towards bedside medicine.

scientific article published on 08 May 2009

Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties

scientific article published on 6 April 2013

Photochemical internalization (PCI)--a novel technology for release of macromolecules from endocytic vesicles.

scientific article published in January 2003

Photochemical internalization (PCI): a new modality for light activation of endocytosed therapeuticals.

scientific article

Photochemical internalization (PCI): a technology for drug delivery.

scientific article published on January 2010

Photochemical internalization enhances cytosolic release of antibiotic and increases its efficacy against staphylococcal infection

scientific article published on 05 June 2018

Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity

scientific article published on 2 May 2013

Photochemical internalization of therapeutic macromolecular agents: a novel strategy to kill multidrug-resistant cancer cells.

scientific article published on 10 August 2006

Photochemical internalization of tumor-targeted protein toxins.

scientific article

Photochemical internalization provides time- and space-controlled endolysosomal escape of therapeutic molecules

scientific article published on 18 June 2010

Photochemical internalization: a new tool for drug delivery.

scientific article published on December 2007

Photochemical internalization: a new tool for gene and oligonucleotide delivery.

scientific article published on January 2010

Photochemical internalization: a novel technology for delivery of macromolecules into cytosol

scientific article published in March 1999

Photochemically stimulated drug delivery increases the cytotoxicity and specificity of EGF-saporin

scientific article published on 8 February 2006

Photochemically-Induced Release of Lysosomal Sequestered Sunitinib: Obstacles for Therapeutic Efficacy

scientific article published on 11 February 2020

Photodynamic therapy targets the mTOR signaling network in vitro and in vivo.

scientific article

Photosensitisation facilitates cross-priming of adjuvant-free protein vaccines and stimulation of tumour-suppressing CD8 T cells

scientific article published on 4 December 2014

Porphyrin-related photosensitizers for cancer imaging and therapeutic applications.

scientific article

Release of gelonin from endosomes and lysosomes to cytosol by photochemical internalization

scientific article published on 01 July 2000

Strongly amphiphilic photosensitizers are not substrates of the cancer stem cell marker ABCG2 and provides specific and efficient light-triggered drug delivery of an EGFR-targeted cytotoxic drug.

scientific article

Sustained EKR inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy ⬇️

scientific article published on March 1, 2013

Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells.

scientific article published on 31 January 2007

The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines

scientific article

Use of 5-aminolevulinic acid esters to improve photodynamic therapy on cells in culture

scientific article published on April 1997

Vascular endothelial cells as targets for photochemical internalization (PCI).

scientific article published on 17 August 2013

Y1068 phosphorylation is the most sensitive target of disulfonated tetraphenylporphyrin-based photodynamic therapy on epidermal growth factor receptor.

scientific article published on 27 April 2007

List of works by Pål Kristian Selbo

177Lu-DOTA-HH1, a novel anti-CD37 radio-immunoconjugate: a study of toxicity in nude mice.

5-Aminolevulinic acid-based photochemical internalization of the immunotoxin MOC31-gelonin generates synergistic cytotoxic effects in vitro

5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin.

Abstracts from the 4th ImmunoTherapy of Cancer Conference: Prague, Czech Republic. 20–22 March 2017.

Circumvention of resistance to photodynamic therapy in doxorubicin-resistant sarcoma by photochemical internalization of gelonin

Design, Characterization, and Evaluation of scFvCD133/rGelonin: A CD133-Targeting Recombinant Immunotoxin for Use in Combination with Photochemical Internalization

Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance.

Disulfonated tetraphenyl chlorin (TPCS2a), a novel photosensitizer developed for clinical utilization of photochemical internalization.

Enhanced photodynamic destruction of a transplantable fibrosarcoma using photochemical internalisation of gelonin

Enhanced targeting of triple-negative breast carcinoma and malignant melanoma by photochemical internalization of CSPG4-targeting immunotoxins.

Epidermal growth factor receptor-targeted photosensitizer selectively inhibits EGFR signaling and induces targeted phototoxicity in ovarian cancer cells

Evaluation of the binding of radiolabeled rituximab to CD20-positive lymphoma cells: an in vitro feasibility study concerning low-dose-rate radioimmunotherapy with the alpha-emitter 227Th

Extracellular phospholipase A2 expression in sarcoidosis

High aldehyde dehydrogenase activity does not protect colon cancer cells against TPCS2a-sensitized photokilling

In vivo documentation of photochemical internalization, a novel approach to site specific cancer therapy

Intracellular re-localisation by photochemical internalisation enhances the cytotoxic effect of gelonin--quantitative studies in normal rat liver.

Intradermal photosensitisation facilitates stimulation of MHC class-I restricted CD8 T-cell responses of co-administered antigen

Light directed gene transfer by photochemical internalisation.

Light-controlled endosomal escape of the novel CD133-targeting immunotoxin AC133-saporin by photochemical internalization - A minimally invasive cancer stem cell-targeting strategy.

Light-triggered, efficient cytosolic release of IM7-saporin targeting the putative cancer stem cell marker CD44 by photochemical internalization.

Mechanistic investigation and implications of photodynamic therapy induction of vascular endothelial growth factor in prostate cancer.

Multi-modality therapeutics with potent anti-tumor effects: photochemical internalization enhances delivery of the fusion toxin scFvMEL/rGel

Photochemical Internalization for Intracellular Drug Delivery. From Basic Mechanisms to Clinical Research

Photochemical Internalization of Peptide Antigens Provides a Novel Strategy to Realize Therapeutic Cancer Vaccination

Photochemical Internalization: Light Paves Way for New Cancer Chemotherapies and Vaccines

Photochemical activation of drugs for the treatment of therapy-resistant cancers

Photochemical disruption of endocytic vesicles before delivery of drugs: a new strategy for cancer therapy.

Photochemical drug and gene delivery

Photochemical internalisation (PCI): a further development of photodynamic therapy for the treatment of skin cancer

Photochemical internalisation in drug and gene delivery.

Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin

Photochemical internalisation, a minimally invasive strategy for light-controlled endosomal escape of cancer stem cell-targeting therapeutics.

Photochemical internalisation: a novel drug delivery system

Photochemical internalization (PCI) in cancer therapy: from bench towards bedside medicine.

Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties

Photochemical internalization (PCI)--a novel technology for release of macromolecules from endocytic vesicles.

Photochemical internalization (PCI): a new modality for light activation of endocytosed therapeuticals.

Photochemical internalization (PCI): a technology for drug delivery.

Photochemical internalization enhances cytosolic release of antibiotic and increases its efficacy against staphylococcal infection

Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity

Photochemical internalization of therapeutic macromolecular agents: a novel strategy to kill multidrug-resistant cancer cells.

Photochemical internalization of tumor-targeted protein toxins.

Photochemical internalization provides time- and space-controlled endolysosomal escape of therapeutic molecules

Photochemical internalization: a new tool for drug delivery.

Photochemical internalization: a new tool for gene and oligonucleotide delivery.

Photochemical internalization: a novel technology for delivery of macromolecules into cytosol

Photochemically stimulated drug delivery increases the cytotoxicity and specificity of EGF-saporin

Photochemically-Induced Release of Lysosomal Sequestered Sunitinib: Obstacles for Therapeutic Efficacy

Photodynamic therapy targets the mTOR signaling network in vitro and in vivo.

Photosensitisation facilitates cross-priming of adjuvant-free protein vaccines and stimulation of tumour-suppressing CD8 T cells

Porphyrin-related photosensitizers for cancer imaging and therapeutic applications.

Release of gelonin from endosomes and lysosomes to cytosol by photochemical internalization

Strongly amphiphilic photosensitizers are not substrates of the cancer stem cell marker ABCG2 and provides specific and efficient light-triggered drug delivery of an EGFR-targeted cytotoxic drug.

Sustained EKR inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy ⬇️

Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells.

The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines

Use of 5-aminolevulinic acid esters to improve photodynamic therapy on cells in culture

Vascular endothelial cells as targets for photochemical internalization (PCI).

Y1068 phosphorylation is the most sensitive target of disulfonated tetraphenylporphyrin-based photodynamic therapy on epidermal growth factor receptor.