List of works - Lilia M. Iakoucheva

A Protein Domain-Based Interactome Network for C. elegans Early Embryogenesis

A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex

scientific article published in 2022

A protein domain-based interactome network for C. elegans early embryogenesis

scientific article

A proteome-scale map of the human interactome network

scientific article

Aberrant mobility phenomena of the DNA repair protein XPA

scientific article

Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling

scientific article published on 16 March 2021

Combining prediction, computation and experiment for the characterization of protein disorder

scientific article published in October 2004

Comprehensive Analyses of Tissue-Specific Networks with Implications to Psychiatric Diseases

scientific article published on January 2017

Cortical organoids model early brain development disrupted by 16p11.2 copy number variants in autism

scientific article published on 26 August 2021

DisProt: a database of protein disorder

scientific article

Disease-associated mutations disrupt functionally important regions of intrinsic protein disorder

scientific article

Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia

scientific article

Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia

scientific article published in Nature

Equilibrium and stop-flow kinetic studies of fluorescently labeled DNA substrates with DNA repair proteins XPA and replication protein A.

scientific article

Extended X-ray absorption fine structure evidence for a single metal binding domain in Xenopus laevis nucleotide excision repair protein XPA.

scientific article

Flexible nets. The roles of intrinsic disorder in protein interaction networks.

scientific article

Frequency and Complexity of De Novo Structural Mutation in Autism

scientific article

Full-length isoform transcriptome of the developing human brain provides further insights into autism

scientific article published on 01 August 2021

Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions.

scientific article

Functional anthology of intrinsic disorder. 2. Cellular components, domains, technical terms, developmental processes, and coding sequence diversities correlated with long disordered regions

scientific article published on 29 March 2007

Functional anthology of intrinsic disorder. 3. Ligands, post-translational modifications, and diseases associated with intrinsically disordered proteins.

scientific article

Graphlet kernels for prediction of functional residues in protein structures

scientific article published on January 2010

Identification, analysis, and prediction of protein ubiquitination sites

scientific article

Inferring the molecular and phenotypic impact of amino acid variants with MutPred2

scientific article published on 20 November 2020

Intrinsic disorder and functional proteomics

scientific article published on 8 December 2006

Intrinsic disorder in cell-signaling and cancer-associated proteins

scientific article (publication date: 25 October 2002)

Intrinsic disorder is a common feature of hub proteins from four eukaryotic interactomes

scientific article

Mapping copy number variation by population-scale genome sequencing

scientific article

Microduplications of 16p11.2 are associated with schizophrenia

scientific article

Order, Disorder, and Flexibility

scientific article published on 01 November 2003

Paternally inherited cis-regulatory structural variants are associated with autism.

scientific article published in April 2018

Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseases

scientific article

Predicted disorder-to-order transition mutations in IκBα disrupt function

scientific article published on 6 March 2014

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

scientific article published on 11 April 2014

Publisher Correction: A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex

correction of a scholarly article

RNA association or phosphorylation of the RS domain prevents aggregation of RS domain-containing proteins

scientific article published in November 2007

Serine/arginine-rich splicing factors belong to a class of intrinsically disordered proteins

scientific article

Single-molecule conformational dynamics of fluctuating noncovalent DNA-protein interactions in DNA damage recognition.

scientific article

Spatiotemporal 16p11.2 protein network implicates cortical late mid-fetal brain development and KCTD13-Cul3-RhoA pathway in psychiatric diseases

scientific article published on February 2015

The importance of intrinsic disorder for protein phosphorylation

scientific article (publication date: 2004)

Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder

scientific article

Two Sample Logo: a graphical representation of the differences between two sets of sequence alignments

scientific article published on 21 April 2006

Unfoldomics of human diseases: linking protein intrinsic disorder with diseases

scientific article

When loss-of-function is loss of function: assessing mutational signatures and impact of loss-of-function genetic variants.

scientific article published in July 2017

Whole-genome sequencing in autism identifies hot spots for de novo germline mutation.

scientific article published on December 2012

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

scientific article published on February 2016

List of works by Lilia M. Iakoucheva

A Protein Domain-Based Interactome Network for C. elegans Early Embryogenesis

A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex

A protein domain-based interactome network for C. elegans early embryogenesis

A proteome-scale map of the human interactome network

Aberrant mobility phenomena of the DNA repair protein XPA

Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling

Combining prediction, computation and experiment for the characterization of protein disorder

Comprehensive Analyses of Tissue-Specific Networks with Implications to Psychiatric Diseases

Cortical organoids model early brain development disrupted by 16p11.2 copy number variants in autism

DisProt: a database of protein disorder

Disease-associated mutations disrupt functionally important regions of intrinsic protein disorder

Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia

Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia

Equilibrium and stop-flow kinetic studies of fluorescently labeled DNA substrates with DNA repair proteins XPA and replication protein A.

Extended X-ray absorption fine structure evidence for a single metal binding domain in Xenopus laevis nucleotide excision repair protein XPA.

Flexible nets. The roles of intrinsic disorder in protein interaction networks.

Frequency and Complexity of De Novo Structural Mutation in Autism

Full-length isoform transcriptome of the developing human brain provides further insights into autism

Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions.

Functional anthology of intrinsic disorder. 2. Cellular components, domains, technical terms, developmental processes, and coding sequence diversities correlated with long disordered regions

Functional anthology of intrinsic disorder. 3. Ligands, post-translational modifications, and diseases associated with intrinsically disordered proteins.

Graphlet kernels for prediction of functional residues in protein structures

Identification, analysis, and prediction of protein ubiquitination sites

Inferring the molecular and phenotypic impact of amino acid variants with MutPred2

Intrinsic disorder and functional proteomics

Intrinsic disorder in cell-signaling and cancer-associated proteins

Intrinsic disorder is a common feature of hub proteins from four eukaryotic interactomes

Mapping copy number variation by population-scale genome sequencing

Microduplications of 16p11.2 are associated with schizophrenia

Order, Disorder, and Flexibility

Paternally inherited cis-regulatory structural variants are associated with autism.

Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseases

Predicted disorder-to-order transition mutations in IκBα disrupt function

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

Publisher Correction: A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex

RNA association or phosphorylation of the RS domain prevents aggregation of RS domain-containing proteins

Serine/arginine-rich splicing factors belong to a class of intrinsically disordered proteins

Single-molecule conformational dynamics of fluctuating noncovalent DNA-protein interactions in DNA damage recognition.

Spatiotemporal 16p11.2 protein network implicates cortical late mid-fetal brain development and KCTD13-Cul3-RhoA pathway in psychiatric diseases

The importance of intrinsic disorder for protein phosphorylation

Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder

Two Sample Logo: a graphical representation of the differences between two sets of sequence alignments

Unfoldomics of human diseases: linking protein intrinsic disorder with diseases

When loss-of-function is loss of function: assessing mutational signatures and impact of loss-of-function genetic variants.

Whole-genome sequencing in autism identifies hot spots for de novo germline mutation.

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing