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List of works by Janine M. LaSalle

15q11.2-13.3 chromatin analysis reveals epigenetic regulation of CHRNA7 with deficiencies in Rett and autism brain.

scientific article

A Prader-Willi locus lncRNA cloud modulates diurnal genes and energy expenditure

scientific article published on 13 June 2013

A comparison of existing global DNA methylation assays to low-coverage whole-genome bisulfite sequencing for epidemiological studies.

scientific article published on 5 January 2017

A genomic point-of-view on environmental factors influencing the human brain methylome ⬇️

scientific article published on July 1, 2011

A meta-analysis of two high-risk prospective cohort studies reveals autism-specific transcriptional changes to chromatin, autoimmune, and environmental response genes in umbilical cord blood

scientific article published on 24 October 2019

A survey of seizures and current treatments in 15q duplication syndrome

scientific article published on 6 February 2014

Automated quantitation of cell-mediated HIV type 1 infection of human syncytiotrophoblast cells by fluorescence in situ hybridization and laser scanning cytometry

scientific article

Biological activity of recombinant human myelin basic protein.

scientific article published in May 1993

Characterization of timed changes in hepatic copper concentrations, methionine metabolism, gene expression, and global DNA methylation in the Jackson toxic milk mouse model of Wilson disease.

scientific article

Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity.

scientific article published on May 2015

Chromosome 15q11-13 duplication syndrome brain reveals epigenetic alterations in gene expression not predicted from copy number.

scientific article

Clonal heterogeneity at allelic methylation sites diagnostic for Prader–Willi and Angelman syndromes ⬇️

scientific article published on February 17, 1998

Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes

scientific article published on 14 October 2020

Cord blood buffy coat DNA methylation is comparable to whole cord blood methylation.

scientific article published on 16 February 2018

Corrigendum: Genome-Wide Analysis of DNA Methylation, Copy Number Variation, and Gene Expression in Monozygotic Twins Discordant for Primary Biliary Cirrhosis

scientific article published on 14 August 2014

Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes.

scientific article published on December 2016

Dental Pulp Stem Cells Model Early Life and Imprinted DNA Methylation Patterns

scientific article published on 29 December 2016

Does HER2/neu expression provide prognostic information in patients with advanced urothelial carcinoma?

scientific article published on September 2002

Domain organization of allele-specific replication within the GABRB3 gene cluster requires a biparental 15q11-13 contribution

scientific article published on 01 April 1995

Early Developmental and Evolutionary Origins of Gene Body DNA Methylation Patterns in Mammalian Placentas

scientific article published on 4 August 2015

Early motor phenotype detection in a female mouse model of Rett syndrome is improved by cross-fostering

scientific article

Elevated methyl-CpG-binding protein 2 expression is acquired during postnatal human brain development and is correlated with alternative polyadenylation.

scientific article

Epigenetic changes of the thioredoxin system in the tx-j mouse model and in patients with Wilson disease

scientific article published on 01 November 2018

Epigenetic investigation of variably X chromosome inactivated genes in monozygotic female twins discordant for primary biliary cirrhosis

scientific article

Epigenetic layers and players underlying neurodevelopment.

scientific article published on 31 May 2013

Epigenetic mechanisms in diurnal cycles of metabolism and neurodevelopment

scientific article

Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3.

scientific article

Epigenetic regulation of UBE3A and roles in human neurodevelopmental disorders.

scientific article

Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers

scientific article published on 01 February 2019

Epigenomic strategies at the interface of genetic and environmental risk factors for autism

scientific article published on 16 May 2013

Erratum: Investigation of modifier genes within copy number variations in Rett syndrome

article

Experience-dependent neuroplasticity of the developing hypothalamus: integrative epigenomic approaches

scientific article published on 10 May 2018

Experience-dependent neuroplasticity of the developing hypothalamus: integrative epigenomic approaches

Expression Changes in Epigenetic Gene Pathways Associated With One-Carbon Nutritional Metabolites in Maternal Blood From Pregnancies Resulting in Autism and Non-Typical Neurodevelopment

scientific article published on 07 November 2020

Expression profiling of clonal lymphocyte cell cultures from Rett syndrome patients

scientific article published on 21 July 2006

Gender influences monoallelic expression of ATP10A in human brain

scientific article

Genome-wide analysis of DNA methylation, copy number variation, and gene expression in monozygotic twins discordant for primary biliary cirrhosis

scientific article published on 28 March 2014

How has the study of the human placenta aided our understanding of partially methylated genes?

scientific article published on December 2013

Immunologic and neurodevelopmental susceptibilities of autism

scientific article

Imprinting regulates mammalian snoRNA-encoding chromatin decondensation and neuronal nucleolar size.

scientific article published on 05 August 2009

Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes

scientific article

Large-scale methylation domains mark a functional subset of neuronally expressed genes.

scientific article

Levels of select PCB and PBDE congeners in human postmortem brain reveal possible environmental involvement in 15q11‐q13 duplication autism spectrum disorder ⬇️

scientific article published on August 29, 2012

Long-lived epigenetic interactions between perinatal PBDE exposure and Mecp2308 mutation.

scientific article

Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome.

scientific article

MECP2 mutations in Rett syndrome adversely affect lymphocyte growth, but do not affect imprinted gene expression in blood or brain.

scientific article published on 25 April 2002

MECP2 promoter methylation and X chromosome inactivation in autism

scientific article published on June 2008

Maternal choline modifies fetal liver copper, gene expression, DNA methylation, and neonatal growth in the tx-j mouse model of Wilson disease

scientific article

MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation.

scientific article

MeCP2 regulates activity-dependent transcriptional responses in olfactory sensory neurons

scientific article published on 9 July 2014

Methylation and gene expression responses to ethanol feeding and betaine supplementation in the cystathionine beta synthase-deficient mouse

scientific article

Mice with an isoform-ablating Mecp2 exon 1 mutation recapitulate the neurologic deficits of Rett syndrome

scientific article

Multiple pathways regulate MeCP2 expression in normal brain development and exhibit defects in autism-spectrum disorders

scientific article (publication date: 15 March 2004)

Neuron-specific impairment of inter-chromosomal pairing and transcription in a novel model of human 15q-duplication syndrome ⬇️

scientific article published on October 1, 2011

Neuronal chromatin dynamics of imprinting in development and disease

scientific article

Paradoxical role of methyl-CpG-binding protein 2 in Rett syndrome.

scientific article published on January 2004

Phosphorylation of distinct sites in MeCP2 modifies cofactor associations and the dynamics of transcriptional regulation

scientific article published on 21 May 2012

Placenta and fetal brain share a neurodevelopmental disorder DNA methylation profile in a mouse model of prenatal PCB exposure

scientific article published on 01 March 2022

Placental methylome analysis from a prospective autism study

scientific article (publication date: 2016)

Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism

scientific article published on 16 February 2022

R-loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation.

scientific article published on 05 August 2013

RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein

scientific journal article

Reciprocal co-regulation of EGR2 and MECP2 is disrupted in Rett syndrome and autism

scientific article

Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation

scientific article

Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions

scientific article

Rett syndrome: a Rosetta stone for understanding the molecular pathogenesis of autism

scientific article

Role of DNMT3B in the regulation of early neural and neural crest specifiers ⬇️

scientific article published on January 1, 2012

Sequence features accurately predict genome-wide MeCP2 binding in vivo.

scientific article published on 24 March 2016

Sex disparate gut microbiome and metabolome perturbations precede disease progression in a mouse model of Rett syndrome

scientific article published on 16 December 2021

Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group.

scientific article published on 31 March 2017

Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex.

scientific article published on 24 April 2018

The coexpression of CD45RA and CD45RO isoforms on T cells during the S/G2/M stages of cell cycle.

scientific article published in November 1991

The comorbidity of autism with the genomic disorders of chromosome 15q11.2-q13

scientific article

The human placenta methylome ⬇️

scientific article published on March 25, 2013

The landscape of DNA methylation amid a perfect storm of autism aetiologies.

scientific article published on 06 May 2016

The role of MeCP2 in brain development and neurodevelopmental disorders

scientific article

UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons.

scientific article published on 19 September 2017

Whole genome bisulfite sequencing of Down syndrome brain reveals regional DNA hypermethylation and novel disorder insights

scientific article published on 06 May 2019

Wilson Disease: Epigenetic effects of choline supplementation on phenotype and clinical course in a mouse model.

scientific article published on 9 September 2016

Wilson's Disease: Changes in Methionine Metabolism and Inflammation Affect Global DNA Methylation in Early Liver Disease ⬇️

scientific article published on January 10, 2013

X chromosome gene methylation in peripheral lymphocytes from monozygotic twins discordant for scleroderma.

scientific article published in September 2012

X-Chromosome inactivation ratios affect wild-type MeCP2 expression within mosaic Rett syndrome and Mecp2-/+ mouse brain.

scientific article

mtDNA depletion-like syndrome in Wilson disease

scientific article published on 30 September 2020

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