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List of works by Daniel Haber

"Oncogenic shock": explaining oncogene addiction through differential signal attenuation

scientific article published on July 2006

A Digital RNA Signature of Circulating Tumor Cells Predicting Early Therapeutic Response in Localized and Metastatic Breast Cancer

scientific article published on 13 August 2018

A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors

scientific article

A blood-based test for epidermal growth factor receptor mutations in lung cancer

scientific article published on 01 July 2006

A common signaling cascade may underlie "addiction" to the Src, BCR-ABL, and EGF receptor oncogenes

scientific article

A computational study of circulating large tumor cells traversing microvessels

scientific article

A conduit to metastasis: circulating tumor cell biology

scientific article published in September 2017

A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression

scientific article published on August 2009

A dose-ranging study of cabozantinib in men with castration-resistant prostate cancer and bone metastases

scientific article published on 03 April 2013

A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration

scientific article

A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers

scientific article

A landscape of pharmacogenomic interactions in cancer.

scientific article published on 05 July 2016

A microfluidic device for label-free, physical capture of circulating tumor cell clusters

scientific article published on 18 May 2015

A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer

scientific article

A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells

scientific article published on 10 February 2020

A recurrent mutation in PALB2 in Finnish cancer families.

scientific article

A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen

scientific article published on June 2004

AR Expression in Breast Cancer CTCs Associates with Bone Metastases.

scientific article published on 16 February 2018

ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells.

scientific article published on 27 February 2017

ATRAID regulates the action of nitrogen-containing bisphosphonates on bone

scientific article published on 01 May 2020

Aberrant overexpression of satellite repeats in pancreatic and other epithelial cancers

scientific article

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

scientific article (publication date: 20 May 2004)

Adenosine transporter ENT4 is a direct target of EWS/WT1 translocation product and is highly expressed in desmoplastic small round cell tumor

scientific article published in 2008

Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors.

scientific article published on January 2015

Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752

scientific article

Amplification-free digital gene expression profiling from minute cell quantities

scientific article

An RNA-Based Digital Circulating Tumor Cell Signature Is Predictive of Drug Response and Early Dissemination in Prostate Cancer

scientific article published on 4 January 2018

An RNA-based signature enables high specificity detection of circulating tumor cells in hepatocellular carcinoma.

scientific article published on 17 January 2017

An X chromosome gene, WTX, is commonly inactivated in Wilms tumor

scientific article

An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background

scientific article

Analysis of the MammaPrint breast cancer assay in a predominantly postmenopausal cohort

scientific article

Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

scientific article

Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer.

scientific article

BRCA1 regulates the interferon gamma-mediated apoptotic response

scientific article

Biodegradable nano-films for capture and non-invasive release of circulating tumor cells.

scientific article published on 20 June 2015

Bioengineered implantable scaffolds as a tool to study stromal-derived factors in metastatic cancer models

scientific article

Biopolymer System for Cell Recovery from Microfluidic Cell Capture Devices

scientific article published on April 3, 2012

Blood-based monitoring identifies acquired and targetable driver HER2 mutations in endocrine-resistant metastatic breast cancer

scientific article published on 16 July 2019

Brain tumor cells in circulation are enriched for mesenchymal gene expression

scientific article

COX-2 mediates tumor-stromal prolactin signaling to initiate tumorigenesis

scientific article published on 28 February 2019

Cancer detection: Seeking signals in blood.

scientific article

Cancer metastasis through the prism of epithelial-to-mesenchymal transition in circulating tumor cells

scientific article

Cancer therapy. Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility.

scientific article

Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes

article

Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes

scientific article published on 04 February 2019

Cell fate: Transition loses its invasive edge

scientific article published on 11 November 2015

Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents

scientific article published on 19 March 2010

Chabner Colloquium: Answering the Big Questions in Cancer Research & 2018 STO Annual MeetingAbstract 1 – Beyond PARP1: Ribosylation as a Target for Cancer TherapyAbstract 2 – Melanoma: Clues to Improved Therapeutic Efficacy from Disease Pathogene

article

Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis

scientific article

Circulating tumor cells: approaches to isolation and characterization

scientific article published on February 7, 2011

Clusters of Circulating Tumor Cells: a Biophysical and Technological Perspective

scientific article published on 10 August 2017

Coexpression of Argonaute-2 enhances RNA interference toward perfect match binding sites

scientific article

Collective and individual migration following the epithelial-mesenchymal transition

scientific article

Combination Olaparib and Temozolomide in Relapsed Small-Cell Lung Cancer

scientific article published on 15 August 2019

Continuous Flow Microfluidic Bioparticle Concentrator.

scientific article published on 10 June 2015

Correlating chemical sensitivity and basal gene expression reveals mechanism of action.

scientific article

DOCK4, a GTPase activator, is disrupted during tumorigenesis

scientific article (publication date: 7 March 2003)

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

scientific article

Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis

scientific article published on 06 February 2020

Detection and Analysis of Circulating Epithelial Cells in Liquid Biopsies From Patients With Liver Disease

scientific article published on 13 September 2018

Detection of T790M, the Acquired Resistance EGFR Mutation, by Tumor Biopsy versus Noninvasive Blood-Based Analyses

scientific article published on 7 October 2015

Does molecular monitoring matter in early-stage breast cancer?

scientific article published on 01 August 2015

Drivers and passengers

scientific article published in Nature

Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression

scientific article published in December 2007

Dynamic chromatin modification sustains epithelial-mesenchymal transition following inducible expression of Snail-1

scientific article

Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma

scientific article

En Route to Metastasis: Circulating Tumor Cell Clusters and Epithelial-to-Mesenchymal Transition

scientific article published on 28 September 2015

Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas

scientific article published on July 2006

Epidermal growth factor receptor mutants from human lung cancers exhibit enhanced catalytic activity and increased sensitivity to gefitinib

scientific article published on March 2007

Epidermal growth factor receptor mutation testing in the care of lung cancer patients

scientific article published on July 2006

Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: molecular analysis of the IDEAL/INTACT gefitinib trials

scientific article

Epidermal growth factor receptor mutations in non-small cell lung cancer: predicting clinical response to kinase inhibitors

scientific article published in August 2005

Epithelial to mesenchymal plasticity and differential response to therapies in pancreatic ductal adenocarcinoma

scientific article published on 16 December 2019

Ex Vivo Culture of CTCs: An Emerging Resource to Guide Cancer Therapy

scientific article published on 21 May 2015

Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib

scientific article

Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination.

scientific article published on 09 February 2017

Familial breast cancer and the hCHK2 1100delC mutation: assessing cancer risk

scientific article

Fantastic voyage: the future of cancer diagnostics

scientific article published on December 2015

First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations

scientific article published on 5 May 2008

Frequent met oncogene amplification in a Brca1/Trp53 mouse model of mammary tumorigenesis

scientific article published on April 2006

Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways

scientific article

Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts

scientific article

Genome Sequencing of Multiple Primary Tumors Reveals a Novel PALB2 Variant

article

Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition.

scientific article published in December 2016

Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors

scientific article

Genomic and Functional Fidelity of Small Cell Lung Cancer Patient-Derived Xenografts.

scientific article published on 26 February 2018

Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells

scientific article

Global regulation of Hox gene expression in C. elegans by a SAM domain protein.

scientific article published in June 2003

HER2 expression identifies dynamic functional states within circulating breast cancer cells

scientific article published on 24 August 2016

HIF1A signaling selectively supports proliferation of breast cancer in the brain

scientific article published on 09 December 2020

Haplotype analysis of two recurrentCDKN2A mutations in 10 melanoma families: Evidence for common founders and independent mutations

article

Highly Multiplexed Fluorescence in Situ Hybridization for in Situ Genomics

scientific article published on 09 March 2019

Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses.

scientific article published on 19 September 2011

Identification of a DNA-binding site and transcriptional target for the EWS-WT1(+KTS) oncoprotein

scientific article

Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling

scholarly article

Identification of somatically acquired BRCA1/2 mutations by cfDNA analysis in patients with metastatic breast cancer

scientific article published on 22 June 2020

Improved Detection of Circulating Epithelial Cells in Patients with Intraductal Papillary Mucinous Neoplasms

scientific article published on 31 August 2017

Improved Detection of Circulating Epithelial Cells in Patients with Intraductal Papillary Mucinous Neoplasms

scientific article published on 01 October 2018

In-flow measurement of cell-cell adhesion using oscillatory inertial microfluidics

scientific article published on 17 April 2020

Inactivation of the tumor suppressor WTX in a subset of pediatric tumors

scientific article published on 05 November 2013

Increased prevalence of EGFR-mutant lung cancer in women and in East Asian populations: analysis of estrogen-related polymorphisms

scientific article

Induction of BAIAP3 by the EWS-WT1 chimeric fusion implicates regulated exocytosis in tumorigenesis.

scientific article

Induction of the interleukin-2/15 receptor beta-chain by the EWS-WT1 translocation product.

scientific article

Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells.

scientific article published on April 2013

Infrequent mutations of Archipelago (hAGO, hCDC4, Fbw7) in primary ovarian cancer

scientific article

Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.

scientific article published on 30 October 2005

Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways

scientific article

Integrating genomic features for non-invasive early lung cancer detection

scientific article published on 25 March 2020

Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib

scientific article

Isolation and characterization of circulating tumor cells from patients with localized and metastatic prostate cancer

scientific article

Isolation and molecular characterization of circulating melanoma cells

scientific article

Isolation of circulating tumor cells using a microvortex-generating herringbone-chip

scientific article

Isolation of rare circulating tumour cells in cancer patients by microchip technology

scientific article

Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment

scientific article (publication date: 2015)

Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors

scientific article published on 14 April 2009

MAPK7 Regulates EMT Features and Modulates the Generation of CTCs

scientific article published on 12 February 2015

MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib

scientific article published on 31 October 2011

Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant

scientific article

Microfluidic Isolation of Circulating Tumor Cell Clusters by Size and Asymmetry

scientific article

Microfluidic concentration and separation of circulating tumor cell clusters from large blood volumes

scientific article published on 14 January 2020

Microfluidic isolation of platelet-covered circulating tumor cells.

scientific article published on 21 September 2017

Microfluidic, marker-free isolation of circulating tumor cells from blood samples

scientific article

Modeling background radiation using geochemical data: A case study in and around Cameron, Arizona

scientific article

Modeling gamma radiation exposure rates using geologic and remote sensing data to locate radiogenic anomalies

scientific article published on 06 September 2019

Modeling oncogene addiction using RNA interference.

scholarly article

Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer

scientific article published on February 2007

Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy

scientific article published on 16 February 2018

Monolithic Chip for High-throughput Blood Cell Depletion to Sort Rare Circulating Tumor Cells

scientific article published on 7 September 2017

Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias

scientific article published on 25 February 2008

Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway

scientific article published on 01 April 2008

Oncogenic activity of epidermal growth factor receptor kinase mutant alleles is enhanced by the T790M drug resistance mutation

scientific article

P2Y-like receptor, GPR105 (P2Y14), identifies and mediates chemotaxis of bone-marrow hematopoietic stem cells

scientific article

Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target

scientific article published on 03 July 2020

Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer

scientific article

Preservative solution that stabilizes erythrocyte morphology and leukocyte viability under ambient conditions

scientific article

Prevalence and functional analysis of sequence variants in the ATR checkpoint mediator Claspin

scientific article

Prophylactic oophorectomy to reduce the risk of ovarian and breast cancer in carriers of BRCA mutations

scientific article published on 20 May 2002

Pulmonary adenocarcinomas with mutant epidermal growth factor receptors

scientific article

Quantitative Analysis of Circulating Tumor Cells Using RNA-Based Digital Scoring

scientific article published on 01 January 2020

REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species

scientific article

RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis

scientific article published on July 26, 2012

RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance.

scientific article

Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

scientific article published on May 2010

Reduced Erlotinib sensitivity of epidermal growth factor receptor-mutant non-small cell lung cancer following cisplatin exposure: a cell culture model of second-line erlotinib treatment

scientific article

Response of some head and neck cancers to epidermal growth factor receptor tyrosine kinase inhibitors may be linked to mutation of ERBB2 rather than EGFR.

scientific article

Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing

scientific article published on 01 January 2007

SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes.

scientific article

SETD1A protects from senescence through regulation of the mitotic gene expression program

scientific article published on 28 June 2019

SUMO modification is required for in vivo Hox gene regulation by the Caenorhabditis elegans Polycomb group protein SOP-2.

scientific article published on 11 April 2004

SUMO-1 modification of the Wilms' tumor suppressor WT1

scientific article

Selective loss of heterozygosity in multiple breast cancers from a carrier of mutations in both BRCA1 and BRCA2

scientific article published on 01 May 2002

Sequence variations of microRNAs in human cancer: alterations in predicted secondary structure do not affect processing.

scientific article published on June 2006

Single-Cell Analysis of Circulating Tumor Cells as a Window into Tumor Heterogeneity

scientific article

Single-cell RNA sequencing identifies extracellular matrix gene expression by pancreatic circulating tumor cells

scientific article

Solidifying liquid biopsies: can circulating tumor cell monitoring guide treatment selection in breast cancer?

Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer

scientific article published on 30 May 2019

Summary statement: novel agents in the treatment of lung cancer: advances in epidermal growth factor receptor-targeted agents

scientific article

TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers.

scientific article

TORC1 Suppression Predicts Responsiveness to RAF and MEK Inhibition in BRAF- Mutant Melanoma

scientific article published on July 31, 2013

The C. elegans Polycomb gene SOP-2 encodes an RNA binding protein

scientific article published in June 2004

The CTC-chip: an exciting new tool to detect circulating tumor cells in lung cancer patients

scientific article published on March 2009

The IGF2 intronic miR-483 selectively enhances transcription from IGF2 fetal promoters and enhances tumorigenesis

scientific article published on December 2013

The Role of Physical Stabilization in Whole Blood Preservation.

scientific article published on 15 February 2016

The T790M "gatekeeper" mutation in EGFR mediates resistance to low concentrations of an irreversible EGFR inhibitor

scientific article published in April 2008

The WTX Tumor Suppressor Enhances p53 Acetylation by CBP/p300

scientific article published on January 26, 2012

The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28.

scientific article

The WTX tumor suppressor regulates mesenchymal progenitor cell fate specification

scientific journal article

The evolving war on cancer

scientific article published on 01 April 2011

The lipogenic regulator SREBF2 induces Transferrin in circulating melanoma cells and suppresses ferroptosis

scientific article published on 17 November 2020

The predominant WT1 isoform (+KTS) encodes a DNA-binding protein targeting the planar cell polarity gene Scribble in renal podocytes.

scientific article

The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity

scholarly article

Transcriptional activation of placental growth factor by the forkhead/winged helix transcription factor FoxD1

scientific journal article

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

scientific article

Tunable nanostructured coating for the capture and selective release of viable circulating tumor cells

scientific article published on 15 January 2015

Ultra-fast vitrification of patient-derived circulating tumor cell lines.

scientific article published on 23 February 2018

Ultrahigh-throughput magnetic sorting of large blood volumes for epitope-agnostic isolation of circulating tumor cells

scientific article published on 08 July 2020

Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase

scientific article

Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish

scientific article published on 25 April 2019

Whole blood stabilization for the microfluidic isolation and molecular characterization of circulating tumor cells.

scientific article published on 23 November 2017

Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network

scientific article

Wilms' tumor with an apparently balanced translocation t(X;18) resulting in deletion of the WTX gene

scientific article published on 01 October 2007

YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway

scientific article

Yeast, flies, worms, and fish in the study of human disease

scientific article

salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

scientific article (publication date: 23 August 2002)