List of works - Bente Finsen

A reeler mutant mouse with a new, spontaneous mutation in the reelin gene.

scientific article published in September 2002

Accelerated microglial pathology is associated with Aβ plaques in mouse models of Alzheimer's disease

scientific article

Age-Dependent Changes in the Sarkosyl-Insoluble Proteome of APPSWE/PS1ΔE9 Transgenic Mice Implicate Dysfunctional Mitochondria in the Pathogenesis of Alzheimer’s Disease

scientific article published on 01 January 2018

Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer's disease

scientific article published on 31 October 2019

Alternative polyadenylation and miR-34 family members regulate tau expression

scientific article published on 18 September 2013

An empirical analysis of the precision of estimating the numbers of neurons and glia in human neocortex using a fractionator-design with sub-sampling

scientific article

An integrated proteomics approach shows synaptic plasticity changes in an APP/PS1 Alzheimer's mouse model

scientific article published on 28 April 2016

Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes

article

Axonal plasticity elicits long-term changes in oligodendroglia and myelinated fibers.

scientific article

Axonal sprouting regulates myelin basic protein gene expression in denervated mouse hippocampus

article

Axotomy-induced glial reactions in normal and cytokine transgenic mice.

scientific article

Behavioural Phenotyping of APPswe/PS1δE9 Mice: Age-Rrelated Changes and Effect of Long-Term Paroxetine Treatment

scientific article

Beneficial potential of intravenously administered IL-6 in improving outcome after murine experimental stroke

scientific article published on 3 June 2017

CD8+ T cells complement antibodies in protecting against yellow fever virus

scientific article

CSF transthyretin neuroprotection in a mouse model of brain ischemia

scientific article published on 11 November 2010

Cell therapy centered on IL-1Ra is neuroprotective in experimental stroke

scientific article published on 9 February 2016

Changes in brain levels of N-acylethanolamines and 2-arachidonoylglycerol in focal cerebral ischemia in mice

Characterization of two novel nuclear BTB/POZ domain zinc finger isoforms. Association with differentiation of hippocampal neurons, cerebellar granule cells, and macroglia

scientific journal article

Characterizing disease-associated changes in post-translational modifications by mass spectrometry

scientific article published on 27 January 2018

Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling

scientific article published on 07 July 2016

Corrigendum to "Neuron and neuroblast numbers and cytogenesis in the dentate gyrus of aged APPswe/PS1dE9transgenic mice: Effect of long-term treatment with paroxetine" [Neurobiol Dis. 2017; 104: 50-60]

scientific article published on 01 April 2019

Cortical Morphogenesis during Embryonic Development Is Regulated by miR-34c and miR-204.

scientific article published on 09 February 2017

Cytokine-producing microglia have an altered beta-amyloid load in aged APP/PS1 Tg mice.

scientific article

Differential impact of interferon regulatory factor 7 in initiation of the type I interferon response in the lymphocytic choriomeningitis virus-infected central nervous system versus the periphery

scientific article

Disruption of the acyl-CoA-binding protein gene delays hepatic adaptation to metabolic changes at weaning

scientific article

Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APP/PS1 Transgenic Mice Implicate Cathepsin Z in Alzheimer's Disease

scientific article published on 06 November 2018

Dynamics of oligodendrocyte responses to anterograde axonal (Wallerian) and terminal degeneration in normal and TNF-transgenic mice

scientific article

Effect of aging and Alzheimer's disease-like pathology on brain monoamines in mice.

scientific article

Effect of monomethyl-fumarate on experimental stroke

scholarly article by Zsolt Illes et al published October 2014 in Journal of Neuroimmunology

Enhanced microglial clearance of myelin debris in T cell-infiltrated central nervous system

scientific article published in August 2009

Established amyloid-β pathology is unaffected by chronic treatment with the selective serotonin reuptake inhibitor paroxetine.

scientific article

Expression and role of CXCL10 during the encephalitic stage of experimental and clinical African trypanosomiasis.

scientific article published in November 2009

Fumarate decreases edema volume and improves functional outcome after experimental stroke.

scientific article

Functional organization of an Mbp enhancer exposes striking transcriptional regulatory diversity within myelinating glia

scientific article published on 28 October 2015

Genetic ablation of soluble tumor necrosis factor with preservation of membrane tumor necrosis factor is associated with neuroprotection after focal cerebral ischemia

scientific article published on 19 October 2015

IFNgamma enhances microglial reactions to hippocampal axonal degeneration

scientific article published on 01 May 2000

Immunohistochemical markers for quantitative studies of neurons and glia in human neocortex

scientific article published on 12 November 2007

In situ hybridization for somatostatin mRNA in the adult rat: cingulate, insular, prepiriform, perirhinal, entorhinal, and retrosplenial cortical regions.

scientific article published in April 1996

In situ hybridization of cytokine mRNA using alkaline phosphatase-labelled oligodeoxynucleotide probes

scientific article published in January 2013

Increased Inflammation and Unchanged Density of Synaptic Vesicle Glycoprotein 2A (SV2A) in the Postmortem Frontal Cortex of Alzheimer's Disease Patients

scientific article published on 05 December 2019

Induction of microglial immunomolecules by anterogradely degenerating mossy fibres in the rat hippocampal formation ⬇️

scientific article published on July 1, 1993

Innate immune responses in central nervous system inflammation ⬇️

scientific article published on May 27, 2011

Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice

scientific article published on 23 October 2008

Interleukin-6 is increased in plasma and cerebrospinal fluid of community-dwelling domestic dogs with acute ischaemic stroke.

scientific article

Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APPswe/PS1ΔE9 Transgenic Mice

scientific article published on 30 July 2019

Microglia and macrophages express tumor necrosis factor receptor p75 following middle cerebral artery occlusion in mice

scientific article published on 11 December 2006

Microglia protect neurons against ischemia by synthesis of tumor necrosis factor.

scientific article

Myelin specific T cells induce inflammasome activation in microglia in zones of axonal degeneration

scholarly article by Manuela Marion Grebing et al published October 2014 in Journal of Neuroimmunology

Myelin-specific T cells induce interleukin-1beta expression in lesion-reactive microglial-like cells in zones of axonal degeneration.

scientific article published on 23 October 2015

Neuroinflammation in Alzheimer's disease

scientific article (publication date: April 2015)

Neuron and neuroblast numbers and cytogenesis in the dentate gyrus of aged APPswe/PS1dE9 transgenic mice: Effect of long-term treatment with paroxetine

scientific article published on 28 April 2017

No effect of ablation of surfactant protein-D on acute cerebral infarction in mice

scientific article

Oral treatment with the NADPH oxidase antagonist apocynin mitigates clinical and pathological features of parkinsonism in the MPTP marmoset model

scientific article published on 17 March 2013

Perforant path lesioning induces sprouting of CA3-associated fibre systems in mouse hippocampal formation

scientific article published on 2 March 2002

Population control of resident and immigrant microglia by mitosis and apoptosis

scientific article published on 28 June 2007

Post-stroke inflammation-target or tool for therapy?

scientific article published on 27 November 2018

Prevention of mouse-rat brain xenograft rejection by a combination therapy of cyclosporin A, prednisolone and azathioprine

scientific article published on 01 January 1995

Proliferating resident microglia express the stem cell antigen CD34 in response to acute neural injury

scientific article published in April 2005

Protective effect of ibuprofen in a rat model of chronic oxaliplatin-induced peripheral neuropathy

scientific article published on 06 August 2019

Proteomic signatures of neuroinflammation in Alzheimer's disease, multiple sclerosis and ischemic stroke

scientific article published on 08 July 2019

Quantification of microglial proliferation and apoptosis by flow cytometry

scientific article published in January 2013

Reactive microgliosis engages distinct responses by microglial subpopulations after minor central nervous system injury

scientific article (publication date: 2005)

Reduced Serotonin Transporter Levels and Inflammation in the Midbrain Raphe of 12 month old APPswe/PSEN1dE9 Mice

scientific article

Serotonin augmentation therapy by escitalopram has minimal effects on amyloid-β levels in early-stage Alzheimer's-like disease in mice.

scientific article published on 12 September 2017

Serotonin depleted APP/PS1 mice as a model to study neuropathology in Alzheimer's dementia

scholarly article by Maurizio Severino et al published July 2011 in Alzheimer's and Dementia

Spatio-temporal regulation of circular RNA expression during porcine embryonic brain development

scientific article

Spontaneous ischaemic stroke lesions in a dog brain: neuropathological characterisation and comparison to human ischaemic stroke.

scientific article published on 13 January 2017

Stimulation of adult oligodendrogenesis by myelin-specific T cells

scientific article

Suppressors of cytokine signaling 1 and 3 are upregulated in brain resident cells in response to virus-induced inflammation of the central nervous system via at least two distinctive pathways

scientific article

TNF deficiency causes alterations in the spatial organization of neurogenic zones and alters the number of microglia and neurons in the cerebral cortex

scientific article published on 07 September 2019

TNFalpha: kill or cure for demyelinating disease?

scientific article

TNFα affects CREB-mediated neuroprotective signaling pathways of synaptic plasticity in neurons as revealed by proteomics and phospho-proteomics

scientific article published on 21 July 2017

Telomere dysfunction reduces microglial numbers without fully inducing an aging phenotype

scientific article published on 14 March 2015

The Function of the Human Interferon- 1a Glycan Determined in Vivo

scientific article published on 29 April 2008

The acyl-CoA binding protein is required for normal epidermal barrier function in mice

scientific article

The postischemic environment differentially impacts teratoma or tumor formation after transplantation of human embryonic stem cell-derived neural progenitors

scientific article published on 25 November 2009

Toll-like receptor 2 signaling in response to brain injury: an innate bridge to neuroinflammation.

scientific article published in December 2006

Tumor necrosis factor and its p55 and p75 receptors are not required for axonal lesion-induced microgliosis in mouse fascia dentata

scientific article published in November 2006

Unbiased cell quantification reveals a continued increase in the number of neocortical neurones during early post-natal development in mice

article

List of works by Bente Finsen

A reeler mutant mouse with a new, spontaneous mutation in the reelin gene.

Accelerated microglial pathology is associated with Aβ plaques in mouse models of Alzheimer's disease

Age-Dependent Changes in the Sarkosyl-Insoluble Proteome of APPSWE/PS1ΔE9 Transgenic Mice Implicate Dysfunctional Mitochondria in the Pathogenesis of Alzheimer’s Disease

Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer's disease

Alternative polyadenylation and miR-34 family members regulate tau expression

An empirical analysis of the precision of estimating the numbers of neurons and glia in human neocortex using a fractionator-design with sub-sampling

An integrated proteomics approach shows synaptic plasticity changes in an APP/PS1 Alzheimer's mouse model

Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes

Axonal plasticity elicits long-term changes in oligodendroglia and myelinated fibers.

Axonal sprouting regulates myelin basic protein gene expression in denervated mouse hippocampus

Axotomy-induced glial reactions in normal and cytokine transgenic mice.

Behavioural Phenotyping of APPswe/PS1δE9 Mice: Age-Rrelated Changes and Effect of Long-Term Paroxetine Treatment

Beneficial potential of intravenously administered IL-6 in improving outcome after murine experimental stroke

CD8+ T cells complement antibodies in protecting against yellow fever virus

CSF transthyretin neuroprotection in a mouse model of brain ischemia

Cell therapy centered on IL-1Ra is neuroprotective in experimental stroke

Changes in brain levels of N-acylethanolamines and 2-arachidonoylglycerol in focal cerebral ischemia in mice

Characterization of two novel nuclear BTB/POZ domain zinc finger isoforms. Association with differentiation of hippocampal neurons, cerebellar granule cells, and macroglia

Characterizing disease-associated changes in post-translational modifications by mass spectrometry

Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling

Corrigendum to "Neuron and neuroblast numbers and cytogenesis in the dentate gyrus of aged APPswe/PS1dE9transgenic mice: Effect of long-term treatment with paroxetine" [Neurobiol Dis. 2017; 104: 50-60]

Cortical Morphogenesis during Embryonic Development Is Regulated by miR-34c and miR-204.

Cytokine-producing microglia have an altered beta-amyloid load in aged APP/PS1 Tg mice.

Differential impact of interferon regulatory factor 7 in initiation of the type I interferon response in the lymphocytic choriomeningitis virus-infected central nervous system versus the periphery

Disruption of the acyl-CoA-binding protein gene delays hepatic adaptation to metabolic changes at weaning

Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APP/PS1 Transgenic Mice Implicate Cathepsin Z in Alzheimer's Disease

Dynamics of oligodendrocyte responses to anterograde axonal (Wallerian) and terminal degeneration in normal and TNF-transgenic mice

Effect of aging and Alzheimer's disease-like pathology on brain monoamines in mice.

Effect of monomethyl-fumarate on experimental stroke

Enhanced microglial clearance of myelin debris in T cell-infiltrated central nervous system

Established amyloid-β pathology is unaffected by chronic treatment with the selective serotonin reuptake inhibitor paroxetine.

Expression and role of CXCL10 during the encephalitic stage of experimental and clinical African trypanosomiasis.

Fumarate decreases edema volume and improves functional outcome after experimental stroke.

Functional organization of an Mbp enhancer exposes striking transcriptional regulatory diversity within myelinating glia

Genetic ablation of soluble tumor necrosis factor with preservation of membrane tumor necrosis factor is associated with neuroprotection after focal cerebral ischemia

IFNgamma enhances microglial reactions to hippocampal axonal degeneration

Immunohistochemical markers for quantitative studies of neurons and glia in human neocortex

In situ hybridization for somatostatin mRNA in the adult rat: cingulate, insular, prepiriform, perirhinal, entorhinal, and retrosplenial cortical regions.

In situ hybridization of cytokine mRNA using alkaline phosphatase-labelled oligodeoxynucleotide probes

Increased Inflammation and Unchanged Density of Synaptic Vesicle Glycoprotein 2A (SV2A) in the Postmortem Frontal Cortex of Alzheimer's Disease Patients

Induction of microglial immunomolecules by anterogradely degenerating mossy fibres in the rat hippocampal formation ⬇️

Innate immune responses in central nervous system inflammation ⬇️

Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice

Interleukin-6 is increased in plasma and cerebrospinal fluid of community-dwelling domestic dogs with acute ischaemic stroke.

Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APPswe/PS1ΔE9 Transgenic Mice

Microglia and macrophages express tumor necrosis factor receptor p75 following middle cerebral artery occlusion in mice

Microglia protect neurons against ischemia by synthesis of tumor necrosis factor.

Myelin specific T cells induce inflammasome activation in microglia in zones of axonal degeneration

Myelin-specific T cells induce interleukin-1beta expression in lesion-reactive microglial-like cells in zones of axonal degeneration.

Neuroinflammation in Alzheimer's disease

Neuron and neuroblast numbers and cytogenesis in the dentate gyrus of aged APPswe/PS1dE9 transgenic mice: Effect of long-term treatment with paroxetine

No effect of ablation of surfactant protein-D on acute cerebral infarction in mice

Oral treatment with the NADPH oxidase antagonist apocynin mitigates clinical and pathological features of parkinsonism in the MPTP marmoset model

Perforant path lesioning induces sprouting of CA3-associated fibre systems in mouse hippocampal formation

Population control of resident and immigrant microglia by mitosis and apoptosis

Post-stroke inflammation-target or tool for therapy?

Prevention of mouse-rat brain xenograft rejection by a combination therapy of cyclosporin A, prednisolone and azathioprine

Proliferating resident microglia express the stem cell antigen CD34 in response to acute neural injury

Protective effect of ibuprofen in a rat model of chronic oxaliplatin-induced peripheral neuropathy

Proteomic signatures of neuroinflammation in Alzheimer's disease, multiple sclerosis and ischemic stroke

Quantification of microglial proliferation and apoptosis by flow cytometry

Reactive microgliosis engages distinct responses by microglial subpopulations after minor central nervous system injury

Reduced Serotonin Transporter Levels and Inflammation in the Midbrain Raphe of 12 month old APPswe/PSEN1dE9 Mice

Serotonin augmentation therapy by escitalopram has minimal effects on amyloid-β levels in early-stage Alzheimer's-like disease in mice.

Serotonin depleted APP/PS1 mice as a model to study neuropathology in Alzheimer's dementia

Spatio-temporal regulation of circular RNA expression during porcine embryonic brain development

Spontaneous ischaemic stroke lesions in a dog brain: neuropathological characterisation and comparison to human ischaemic stroke.

Stimulation of adult oligodendrogenesis by myelin-specific T cells

Suppressors of cytokine signaling 1 and 3 are upregulated in brain resident cells in response to virus-induced inflammation of the central nervous system via at least two distinctive pathways

TNF deficiency causes alterations in the spatial organization of neurogenic zones and alters the number of microglia and neurons in the cerebral cortex

TNFalpha: kill or cure for demyelinating disease?

TNFα affects CREB-mediated neuroprotective signaling pathways of synaptic plasticity in neurons as revealed by proteomics and phospho-proteomics

Telomere dysfunction reduces microglial numbers without fully inducing an aging phenotype

The Function of the Human Interferon- 1a Glycan Determined in Vivo

The acyl-CoA binding protein is required for normal epidermal barrier function in mice

The postischemic environment differentially impacts teratoma or tumor formation after transplantation of human embryonic stem cell-derived neural progenitors

Toll-like receptor 2 signaling in response to brain injury: an innate bridge to neuroinflammation.

Tumor necrosis factor and its p55 and p75 receptors are not required for axonal lesion-induced microgliosis in mouse fascia dentata

Unbiased cell quantification reveals a continued increase in the number of neocortical neurones during early post-natal development in mice