List of works - Samuel Gerritz

A Novel Small Molecule Inhibitor of Hepatitis C Virus Entry ⬇️

scientific article published on September 2, 2010

A high-throughput screen for receptor protein tyrosine phosphatase-gamma selective inhibitors

scientific article published on 15 March 2011

Acyl Guanidine Inhibitors of β-Secretase (BACE-1): Optimization of a Micromolar Hit to a Nanomolar Lead via Iterative Solid- and Solution-Phase Library Synthesis ⬇️

scientific article published on October 2, 2012

Attachment of unreactive amines to the solid support: synthesis of phenyl-substituted anilines, 2-aminopyridines, and 2-aminopyrimidines

scientific article published on 01 May 2003

Biochemical and behavioral effects of PDE10A inhibitors: Relationship to target site occupancy

scientific article published on 29 October 2015

Discovery and optimization of (R)-prolinol-derived agonists of the Growth Hormone Secretagogue receptor (GHSR).

scientific article

Discovery of positive allosteric modulators and silent allosteric modulators of the μ-opioid receptor

scientific article

Discovery of pyrazine carboxamide CB1 antagonists: the introduction of a hydroxyl group improves the pharmaceutical properties and in vivo efficacy of the series

scientific article published on 29 April 2007

Discovery, synthesis, and molecular pharmacology of selective positive allosteric modulators of the δ-opioid receptor

scientific article

High-throughput manual parallel synthesis using SynPhase crowns and lanterns.

scientific article

High-throughput screening and rapid inhibitor triage using an infectious chimeric Hepatitis C virus

scientific article

Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780.

scientific article

Influenza nucleoprotein: promising target for antiviral chemotherapy.

scientific article published on 26 July 2012

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers ⬇️

scientific article published on September 6, 2011

Ligand-Based Discovery of a New Scaffold for Allosteric Modulation of the μ-Opioid Receptor

scientific article

Macrocyclic prolinyl acyl guanidines as inhibitors of β-secretase (BACE).

scientific article published on 20 October 2015

Quantitative techniques for the comparison of solid supports.

scientific article

Small molecule receptor protein tyrosine phosphatase γ (RPTPγ) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop

scientific article

Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: Development of chemical probe ML315 ⬇️

scientific article published on March 30, 2013

Solid phase synthesis of 1,5-diarylpyrazole-4-carboxamides: discovery of antagonists of the CB-1 receptor.

scientific article

Solid-phase synthesis and anti-infective activity of a combinatorial library based on the natural product anisomycin.

scientific article published in September 2005

Solid-phase synthesis of a library based on biphenyl-containing trypsin-like serine protease inhibitors

scientific article published on 17 September 2009

Synthesis and applications of a novel polymer-supported EEDQ reagent

scientific article published on 18 July 2007

Using one- and two-dimensional NMR techniques to characterize reaction products bound to Chiron SynPhase crowns

scientific article published on 01 March 2000

List of works by Samuel Gerritz

A Novel Small Molecule Inhibitor of Hepatitis C Virus Entry ⬇️

A high-throughput screen for receptor protein tyrosine phosphatase-gamma selective inhibitors

Acyl Guanidine Inhibitors of β-Secretase (BACE-1): Optimization of a Micromolar Hit to a Nanomolar Lead via Iterative Solid- and Solution-Phase Library Synthesis ⬇️

Attachment of unreactive amines to the solid support: synthesis of phenyl-substituted anilines, 2-aminopyridines, and 2-aminopyrimidines

Biochemical and behavioral effects of PDE10A inhibitors: Relationship to target site occupancy

Discovery and optimization of (R)-prolinol-derived agonists of the Growth Hormone Secretagogue receptor (GHSR).

Discovery of positive allosteric modulators and silent allosteric modulators of the μ-opioid receptor

Discovery of pyrazine carboxamide CB1 antagonists: the introduction of a hydroxyl group improves the pharmaceutical properties and in vivo efficacy of the series

Discovery, synthesis, and molecular pharmacology of selective positive allosteric modulators of the δ-opioid receptor

High-throughput manual parallel synthesis using SynPhase crowns and lanterns.

High-throughput screening and rapid inhibitor triage using an infectious chimeric Hepatitis C virus

Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780.

Influenza nucleoprotein: promising target for antiviral chemotherapy.

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers ⬇️

Ligand-Based Discovery of a New Scaffold for Allosteric Modulation of the μ-Opioid Receptor

Macrocyclic prolinyl acyl guanidines as inhibitors of β-secretase (BACE).

Quantitative techniques for the comparison of solid supports.

Small molecule receptor protein tyrosine phosphatase γ (RPTPγ) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop

Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: Development of chemical probe ML315 ⬇️

Solid phase synthesis of 1,5-diarylpyrazole-4-carboxamides: discovery of antagonists of the CB-1 receptor.

Solid-phase synthesis and anti-infective activity of a combinatorial library based on the natural product anisomycin.

Solid-phase synthesis of a library based on biphenyl-containing trypsin-like serine protease inhibitors

Synthesis and applications of a novel polymer-supported EEDQ reagent

Using one- and two-dimensional NMR techniques to characterize reaction products bound to Chiron SynPhase crowns