List of works - Mohamed L. Salem

5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis.

scientific article published in July 2005

A role for the peripheral blood fibrocyte in leishmaniasis?

scientific article published on 01 January 2004

Acute inflammation induces immunomodulatory effects on myeloid cells associated with anti-tumor responses in a tumor mouse model.

scientific article published on 19 June 2015

Anti-fibrotic potential of human umbilical cord mononuclear cells and mouse bone marrow cells in CCl4- induced liver fibrosis in mice

scientific article

Association between the HER2 expression and histological differentiation in Wilms tumor.

scientific article

Bone marrow mononuclear cells enhance anti-inflammatory effects of pravastatin against isoproterenol-induced myocardial infarction in rats

scientific article published on 25 November 2015

Chemotherapy alters the increased numbers of myeloid-derived suppressor and regulatory T cells in children with acute lymphoblastic leukemia

scientific article published in February 2018

Correlation of viral load with bone marrow and hematological changes in pale patients with chronic hepatitis C virus ⬇️

scientific article published on May 9, 2012

Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a Flt3 ligand-dependent expansion of dendritic cells.

scientific article

Defining the ability of cyclophosphamide preconditioning to enhance the antigen-specific CD8+ T-cell response to peptide vaccination: creation of a beneficial host microenvironment involving type I IFNs and myeloid cells

scientific article published on 01 January 2007

Defining the critical hurdles in cancer immunotherapy

scientific article published on 14 December 2011

Dendritic cell recovery post-lymphodepletion: a potential mechanism for anti-cancer adoptive T cell therapy and vaccination

scientific article

Effect of administration timing of postchemotherapy granulocyte colony-stimulating factor on host-immune cell recovery and CD8+ T-cell response.

scientific article published on 15 July 2016

Effects of local delivery of tetradecylthioacetic acid within the injured coronary vessel wall

scientific article published on 25 September 2012

Enhanced anticancer effect and reduced toxicity of doxorubicin in combination with thymoquinone released from poly-N-acetyl glucosamine nanomatrix in mice bearing solid Ehrlish carcinoma

scientific article published on 7 September 2017

EpCAM is overexpressed in breast cancer and is a potential target for breast cancer gene therapy

scientific article

Estrogen, a double-edged sword: modulation of TH1- and TH2-mediated inflammations by differential regulation of TH1/TH2 cytokine production.

scientific article published on March 2004

Ex vivo interleukin-12-priming during CD8(+) T cell activation dramatically improves adoptive T cell transfer antitumor efficacy in a lymphodepleted host.

scientific article

G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses

scientific article published on October 2013

High numbers of myeloid derived suppressor cells in peripheral blood and ascitic fluid of cirrhotic and HCC patients.

scientific article published on 28 November 2017

IFN-α-based treatment of patients with chronic HCV show increased levels of cells with myeloid-derived suppressor cell phenotype and of IDO and NOS.

scientific article

Immunobiology and signaling pathways of cancer stem cells: implication for cancer therapy.

scientific article

Immunomodulatory and therapeutic properties of the Nigella sativa L. seed.

scientific article

In vitro and in vivo antitumor effects of the Egyptian scorpion Androctonus amoreuxi venom in an Ehrlich ascites tumor model.

scientific article published on 10 May 2016

In vivo acute depletion of CD8+ T cells before murine cytomegalovirus infection upregulated innate antiviral activity of natural killer cells

scientific article published on 01 September 2000

Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8(+) T cells.

scientific article published on 13 February 2015

Kinetics of rebounding of lymphoid and myeloid cells in mouse peripheral blood, spleen and bone marrow after treatment with cyclophosphamide.

scientific article published on March 2012

Mechanisms of enhanced antigen-specific T cell response following vaccination with a novel peptide-based cancer vaccine and systemic interleukin-2 (IL-2)

scientific article published on 01 June 2003

Priming of naive CD8+ T cells in the presence of IL-12 selectively enhances the survival of CD8+CD62Lhi cells and results in superior anti-tumor activity in a tolerogenic murine model.

scientific article

Programmed death-1/programmed death-L1 signaling pathway and its blockade in hepatitis C virus immunotherapy

scientific article

Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus infection

scientific article published on 01 September 2000

Protective effects of Nigella sativa oil and thymoquinone against toxicity induced by the anticancer drug cyclophosphamide.

scientific article published in January 2010

Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C)

scientific article

Review: novel nonviral delivery approaches for interleukin-12 protein and gene systems: curbing toxicity and enhancing adjuvant activity.

scientific article published on September 2006

Synergistic combination of murine bone marrow-derived dendritic cells loaded ex vivo with whole tumor lysate and systemic chemotherapy mediates antitumor immune responses in vivo.

scientific article

Systemic administration of IL-15 augments the antigen-specific primary CD8+ T cell response following vaccination with peptide-pulsed dendritic cells.

scientific article published on November 2002

The adjuvant effects of the toll-like receptor 3 ligand polyinosinic-cytidylic acid poly (I:C) on antigen-specific CD8+ T cell responses are partially dependent on NK cells with the induction of a beneficial cytokine milieu

scientific article published on 02 May 2006

The potential use of Toll-like receptor agonists to restore the dysfunctional immunity induced by hepatitis C virus.

scientific article published on 06 March 2010

The use of dendritic cells for peptide-based vaccination in cancer immunotherapy.

scientific article published on January 2014

Thymoquinone, the active ingredient of Nigella sativa seeds, enhances survival and activity of antigen-specific CD8-positive T cells in vitro

scientific article published on 01 January 2011

Treatment of chronic refractory angina pectoris--light at the end of the tunnel?

scientific article published on 22 March 2006

Triggering of toll-like receptor signaling pathways in T cells contributes to the anti-tumor efficacy of T cell responses.

scientific article published on 23 February 2011

Understanding the biology of ex vivo-expanded CD8 T cells for adoptive cell therapy: role of CD62L.

scientific article published in December 2013

Vaccination with poly(IC:LC) and peptide-pulsed autologous dendritic cells in patients with pancreatic cancer.

scientific article published on 07 April 2017

List of works by Mohamed L. Salem

5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis.

A role for the peripheral blood fibrocyte in leishmaniasis?

Acute inflammation induces immunomodulatory effects on myeloid cells associated with anti-tumor responses in a tumor mouse model.

Anti-fibrotic potential of human umbilical cord mononuclear cells and mouse bone marrow cells in CCl4- induced liver fibrosis in mice

Association between the HER2 expression and histological differentiation in Wilms tumor.

Bone marrow mononuclear cells enhance anti-inflammatory effects of pravastatin against isoproterenol-induced myocardial infarction in rats

Chemotherapy alters the increased numbers of myeloid-derived suppressor and regulatory T cells in children with acute lymphoblastic leukemia

Correlation of viral load with bone marrow and hematological changes in pale patients with chronic hepatitis C virus ⬇️

Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a Flt3 ligand-dependent expansion of dendritic cells.

Defining the ability of cyclophosphamide preconditioning to enhance the antigen-specific CD8+ T-cell response to peptide vaccination: creation of a beneficial host microenvironment involving type I IFNs and myeloid cells

Defining the critical hurdles in cancer immunotherapy

Dendritic cell recovery post-lymphodepletion: a potential mechanism for anti-cancer adoptive T cell therapy and vaccination

Effect of administration timing of postchemotherapy granulocyte colony-stimulating factor on host-immune cell recovery and CD8+ T-cell response.

Effects of local delivery of tetradecylthioacetic acid within the injured coronary vessel wall

Enhanced anticancer effect and reduced toxicity of doxorubicin in combination with thymoquinone released from poly-N-acetyl glucosamine nanomatrix in mice bearing solid Ehrlish carcinoma

EpCAM is overexpressed in breast cancer and is a potential target for breast cancer gene therapy

Estrogen, a double-edged sword: modulation of TH1- and TH2-mediated inflammations by differential regulation of TH1/TH2 cytokine production.

Ex vivo interleukin-12-priming during CD8(+) T cell activation dramatically improves adoptive T cell transfer antitumor efficacy in a lymphodepleted host.

G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses

High numbers of myeloid derived suppressor cells in peripheral blood and ascitic fluid of cirrhotic and HCC patients.

IFN-α-based treatment of patients with chronic HCV show increased levels of cells with myeloid-derived suppressor cell phenotype and of IDO and NOS.

Immunobiology and signaling pathways of cancer stem cells: implication for cancer therapy.

Immunomodulatory and therapeutic properties of the Nigella sativa L. seed.

In vitro and in vivo antitumor effects of the Egyptian scorpion Androctonus amoreuxi venom in an Ehrlich ascites tumor model.

In vivo acute depletion of CD8+ T cells before murine cytomegalovirus infection upregulated innate antiviral activity of natural killer cells

Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8(+) T cells.

Kinetics of rebounding of lymphoid and myeloid cells in mouse peripheral blood, spleen and bone marrow after treatment with cyclophosphamide.

Mechanisms of enhanced antigen-specific T cell response following vaccination with a novel peptide-based cancer vaccine and systemic interleukin-2 (IL-2)

Priming of naive CD8+ T cells in the presence of IL-12 selectively enhances the survival of CD8+CD62Lhi cells and results in superior anti-tumor activity in a tolerogenic murine model.

Programmed death-1/programmed death-L1 signaling pathway and its blockade in hepatitis C virus immunotherapy

Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus infection

Protective effects of Nigella sativa oil and thymoquinone against toxicity induced by the anticancer drug cyclophosphamide.

Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C)

Review: novel nonviral delivery approaches for interleukin-12 protein and gene systems: curbing toxicity and enhancing adjuvant activity.

Synergistic combination of murine bone marrow-derived dendritic cells loaded ex vivo with whole tumor lysate and systemic chemotherapy mediates antitumor immune responses in vivo.

Systemic administration of IL-15 augments the antigen-specific primary CD8+ T cell response following vaccination with peptide-pulsed dendritic cells.

The adjuvant effects of the toll-like receptor 3 ligand polyinosinic-cytidylic acid poly (I:C) on antigen-specific CD8+ T cell responses are partially dependent on NK cells with the induction of a beneficial cytokine milieu

The potential use of Toll-like receptor agonists to restore the dysfunctional immunity induced by hepatitis C virus.

The use of dendritic cells for peptide-based vaccination in cancer immunotherapy.

Thymoquinone, the active ingredient of Nigella sativa seeds, enhances survival and activity of antigen-specific CD8-positive T cells in vitro

Treatment of chronic refractory angina pectoris--light at the end of the tunnel?

Triggering of toll-like receptor signaling pathways in T cells contributes to the anti-tumor efficacy of T cell responses.

Understanding the biology of ex vivo-expanded CD8 T cells for adoptive cell therapy: role of CD62L.

Vaccination with poly(IC:LC) and peptide-pulsed autologous dendritic cells in patients with pancreatic cancer.