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List of works by Dan Littman

A Clonogenic Bone Marrow Progenitor Specific for Macrophages and Dendritic Cells

scientific article published on 01 December 2005

A Comprehensive Map of the Monocyte-Derived Dendritic Cell Transcriptional Network Engaged upon Innate Sensing of HIV

scientific article published on 01 January 2020

A Listeria monocytogenes Bacteriocin Can Target the Commensal Prevotella copri and Modulate Intestinal Infection

scientific article published on 01 November 2019

A chemokine, SDF-1, reduces the effectiveness of multiple axonal repellents and is required for normal axon pathfinding.

scientific article published in February 2003

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

scientific article

A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes

scientific journal article

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

scientific article

A rare intestinal infection with systemic effects ⬇️

scientific article published on January 1, 2012

A validated regulatory network for Th17 cell specification

scientific journal article

Actin Dynamics Regulates Dendritic Cell-Mediated Transfer of HIV-1 to T Cells

scientific article published on 27 January 2016

After Hrs with HIV

scientific article

An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses

scientific article

An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses

scientific article published on 14 January 2016

An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells

scientific article (publication date: 2004)

Attenuation of acute graft-versus-host disease in the absence of the transcription factor RORγt

scientific article

Author Correction: Bile acid metabolites control TH17 and Treg cell differentiation

scientific article published on 01 March 2020

Author Correction: c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont

scientific article published on 01 February 2019

BCR selection and affinity maturation in Peyer's patch germinal centres

scientific article published on 06 May 2020

Bile acid metabolites control TH17 and Treg cell differentiation

scientific article published on 27 November 2019

CD11chigh dendritic cell ablation impairs lymphopenia-driven proliferation of naive and memory CD8+ T cells

scientific article published in November 2005

CD4-specific transgenic expression of human cyclin T1 markedly increases human immunodeficiency virus type 1 (HIV-1) production by CD4+ T lymphocytes and myeloid cells in mice transgenic for a provirus encoding a monocyte-tropic HIV-1 isolate

scientific article

CD8alphaalpha-mediated survival and differentiation of CD8 memory T cell precursors

scientific article published in April 2004

CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance

scientific article (publication date: 14 January 2005)

CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance

scientific article

CXCR4 acts as a costimulator during thymic beta-selection

scientific article

CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity ⬇️

scientific article

CX₃CR1⁺ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22.

scientific article

Canonical and alternate functions of the microRNA biogenesis machinery.

scientific article

Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation.

scientific article published on 26 April 2007

Characterization of Interleukin-17–Producing Regulatory T Cells in Inflamed Intestinal Mucosa From Patients With Inflammatory Bowel Diseases ⬇️

scientific article published on December 11, 2010

Characterization of Transcriptional Regulatory Networks that Promote and Restrict Identities and Functions of Intestinal Innate Lymphoid Cells

scientific article published on 02 July 2019

Chemokine requirements for B cell entry to lymph nodes and Peyer's patches.

scientific article

Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E.

scientific article

Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression

scientific article published in May 2002

Control of microglial neurotoxicity by the fractalkine receptor

scientific journal article

Critical Role for the Microbiota in CX3CR1+ Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses

scientific article published on 03 July 2018

Critical role of IRF1 and BATF in forming chromatin landscape during type 1 regulatory cell differentiation.

scientific article published on 6 February 2017

Cutting edge: organogenesis of nasal-associated lymphoid tissue (NALT) occurs independently of lymphotoxin-alpha (LT alpha) and retinoic acid receptor-related orphan receptor-gamma, but the organization of NALT is LT alpha dependent

scientific article published in February 2002

DC-SIGN-mediated internalization of HIV is required for trans-enhancement of T cell infection

scientific article published on 01 January 2002

DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions

scientific article published on 16 December 2015

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

scientific article

Deciphering the regulatory landscape of fetal and adult γδ T-cell development at single-cell resolution

scientific article published on 08 June 2020

Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease

scientific article

Dendritic cell-mediated trans-enhancement of human immunodeficiency virus type 1 infectivity is independent of DC-SIGN

scientific article published on 20 December 2006

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development

scientific article published in November 2002

Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity

scientific article

Disrupting Hepatocyte Cyp51 from Cholesterol Synthesis Leads to Progressive Liver Injury in the Developing Mouse and Decreases RORC Signalling

scientific article published on 18 January 2017

Distinct Polysaccharide Utilization Profiles of Human Intestinal Prevotella copri Isolates

scientific article published on 01 November 2019

Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.

scientific article published on 2 March 2017

Do the Microbiota Influence Vaccines and Protective Immunity to Pathogens? If So, Is There Potential for Efficacious Microbiota-Based Vaccines?

scientific article published on 21 April 2017

Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs

scientific article published on 17 June 2012

Dynamic microRNA gene transcription and processing during T cell development.

scientific article

Epigenetic gene silencing by Runx proteins

scientific article published on May 2004

Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells.

scientific article

Erratum: Corrigendum: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions

scientific article published in Nature

Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation

scientific article published in November 2002

Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

scientific article published in 2013

Feeding-dependent VIP neuron-ILC3 circuit regulates the intestinal barrier

scientific article published on 12 February 2020

Flexible use of nuclear import pathways by HIV-1.

scientific article

Focused specificity of intestinal TH17 cells towards commensal bacterial antigens

scientific article

From the Thymus to the Mucosa: A Three-Decade Journey

scientific article published in October 2017

Functional and molecular analysis of the double-positive stage-specific CD8 enhancer E8III during thymocyte development.

scientific article published on February 2005

GPR15-mediated homing controls immune homeostasis in the large intestine mucosa

scientific journal article

Generation and characterization of ecto-ADP-ribosyltransferase ART2.1/ART2.2-deficient mice

scientific article

Genetic evidence supporting selection of the Valpha14i NKT cell lineage from double-positive thymocyte precursors

scientific article published in June 2005

HIV immunology needs a new direction

scientific article published on 01 October 2008

HIV's vagina travelogue

scientific article published on February 2007

Harnessing CD4+ T cell responses in HIV vaccine development ⬇️

scientific article published on February 6, 2013

Heritable Gene Regulation in the CD4:CD8 T Cell Lineage Choice.

scientific article published on 22 March 2017

Hiding in plain sight: how HIV evades innate immune responses

scientific article published on October 2011

How Thymocytes Achieve Their Fate.

scientific article published in March 2016

How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets

scientific article

Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo.

scientific article published on 13 January 2009

Human immunodeficiency virus type 1 activates plasmacytoid dendritic cells and concomitantly induces the bystander maturation of myeloid dendritic cells

scientific article published on May 2004

Human microbiome science: vision for the future, Bethesda, MD, July 24 to 26, 2013

scientific article

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

scientific article (publication date: September 2007)

Identification of IL-17-producing FOXP3+ regulatory T cells in humans.

scholarly article

Identification of Potent and Selective Diphenylpropanamide RORγ Inhibitors

scientific article published on January 2013

Identification of a major co-receptor for primary isolates of HIV-1

scientific article

Identification of natural RORγ ligands that regulate the development of lymphoid cells

scientific article

Immunology. Asymmetry and immune memory

scientific article published in March 2007

Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking

scientific article

Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin

scientific article published in April 2012

Induction of intestinal Th17 cells by segmented filamentous bacteria

scientific article (publication date: 30 October 2009)

Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin

scientific article published on 23 November 2008

Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.

scientific article published on April 2010

Interactions Between the Microbiota and the Immune System ⬇️

scientific article published on June 6, 2012

Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense.

scientific article published on 2 February 2012

Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids

scientific article

Leveraging chromatin accessibility for transcriptional regulatory network inference in T Helper 17 Cells

Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma

scientific article published on 25 August 2008

Lineage diversion of T cell receptor transgenic thymocytes revealed by lineage fate mapping.

scientific article

Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22

scientific article

Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring

scientific article published on 13 September 2017

Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity.

scientific article published on 19 March 2014

Mice Transgenic for CD4-Specific Human CD4, CCR5 and Cyclin T1 Expression: A New Model for Investigating HIV-1 Transmission and Treatment Efficacy ⬇️

scientific article published on May 15, 2013

Mice deficient in the chemokine receptor CXCR4 exhibit impaired limb innervation and myogenesis

scientific article published on 29 September 2005

Microbiome in Inflammatory Arthritis and Human Rheumatic Diseases.

scientific article published on 2 September 2015

Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX(3)CR1(hi) cells

scientific article published on 13 January 2013

Microbiota: host interactions in mucosal homeostasis and systemic autoimmunity

scientific article

Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor.

scientific article

Modulation of immune homeostasis by commensal bacteria ⬇️

scientific article published on January 5, 2011

Multiple ITAM-coupled NK-cell receptors engage the Bcl10/Malt1 complex via Carma1 for NF-kappaB and MAPK activation to selectively control cytokine production.

scientific article published on 11 January 2008

Murine T cells potently restrict human immunodeficiency virus infection

scientific article

Myd88 is required for an antibody response to retroviral infection

scientific article

NK cell-activating receptors require PKC-theta for sustained signaling, transcriptional activation, and IFN-gamma secretion.

scientific article published on 10 September 2008

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells

scientific article

New traffic light on Th17 Avenue

scientific article published on 8 December 2017

Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy

scientific article published on 24 June 2020

Nonredundant function of soluble LTα3 produced by innate lymphoid cells in intestinal homeostasis

scientific article

Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection.

scientific article

Nuclear hormone receptors in T lymphocytes

scientific article

Opposing Effects of PKCθ and WASp on Symmetry Breaking and Relocation of the Immunological Synapse

scholarly article by Tasha N. Sims et al published May 2007 in Cell

PKC-theta knockout mice are protected from fat-induced insulin resistance

scientific article

PKCtheta signals activation versus tolerance in vivo

scientific article

Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis

scientific article

Plasticity of CD4+ T cell lineage differentiation.

scientific article

Progress toward a human CD4/CCR5 transgenic rat model for de novo infection by human immunodeficiency virus type 1.

scientific article published in March 2002

Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101)

scientific article

Protein kinase C betaII regulates Akt phosphorylation on Ser-473 in a cell type- and stimulus-specific fashion.

scientific article published on 9 September 2004

Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses

scientific journal article

Protein kinase C-theta;: signaling from the center of the T-cell synapse

scientific article

Quantitative Measurements of HIV-1 and Dextran Capture by Human Monocyte-derived Dendritic Cells (MDDCs).

scientific article

RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F.

scientific article

RUNX proteins in transcription factor networks that regulate T-cell lineage choice

scientific article published on February 2009

RUNX transcription factor-mediated association of Cd4 and Cd8 enables coordinate gene regulation

scientific article

Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes

scientific article (publication date: 11 July 2002)

Regulated movement of CD4 in and out of the immunological synapse

scientific article

Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages

scientific article published on June 2015

Regulation of RORγt in Inflammatory Lymphoid Cell Differentiation

scientific article published on 11 March 2016

Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes.

scientific article published on 22 April 2002

Regulatory T cells suppress development of colitis, blocking differentiation of T-helper 17 into alternative T-helper 1 cells

scientific article published on 7 June 2011

Releasing the Brakes on Cancer Immunotherapy

scientific article published on 01 September 2015

Relief of preintegration inhibition and characterization of additional blocks for HIV replication in primary mouse T cells.

scientific article published on 30 April 2008

Repression of interleukin-4 in T helper type 1 cells by Runx/Cbf beta binding to the Il4 silencer

scientific article published on 23 July 2007

Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation

scientific journal article

Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut.

scientific article published on 24 July 2008

Reshaping of the Dendritic Cell Chromatin Landscape and Interferon Pathways during HIV Infection

scientific article published in March 2018

Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone

scientific article published on 20 April 2008

Retraction Note: DDX5 and its associated lncRNA Rmrp modulate T17 cell effector functions

scientific article published in Nature

Reversing behavioural abnormalities in mice exposed to maternal inflammation

scientific article published on 13 September 2017

Role for CXCR6 in recruitment of activated CD8+ lymphocytes to inflamed liver.

scientific article published in January 2005

Role of the Commensal Microbiota in Normal and Pathogenic Host Immune Responses ⬇️

scientific article published on October 20, 2011

Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells

scientific article published on 20 September 2009

Runx1 prevents wasting, myofibrillar disorganization, and autophagy of skeletal muscle

scientific article published on July 2005

Runx1 protects hematopoietic stem/progenitor cells from oncogenic insult

scientific article published on 06 September 2007

Runx3 regulates integrin alpha E/CD103 and CD4 expression during development of CD4-/CD8+ T cells

scientific article published on August 2005

SIRT1 deacetylates RORγt and enhances Th17 cell generation

scientific article published on 27 April 2015

SIRT1 deacetylates RORγt and enhances Th17 cell generation

scientific article published on 18 May 2015

Segmented Filamentous Bacteria Provoke Lung Autoimmunity by Inducing Gut-Lung Axis Th17 Cells Expressing Dual TCRs

scientific article

Selection and lineage specification in the thymus: commitment 4-stalled

scientific article published in July 2005

Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease

scientific article published on 19 December 2019

Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease

scientific article published on 01 December 2020

Short- and long-term effects of oral vancomycin on the human intestinal microbiota

scientific article published on 05 October 2016

Small molecule inhibitors of RORγt: targeting Th17 cells and other applications

scientific article

Sparse and compositionally robust inference of microbial ecological networks ⬇️

scientific article published on 7 May 2015

Species-specific restriction of apobec3-mediated hypermutation

scientific article

Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine

scientific article

Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development

scientific article published in Nature Communications

Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis

scientific article

Susceptibility of human Th17 cells to human immunodeficiency virus and their perturbation during infection.

scientific article

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

scientific article

Tcf1 and Lef1 pack their own HDAC.

scientific article published in May 2016

Th17 and regulatory T cells in mediating and restraining inflammation

scientific article

ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage

scientific article published on 7 September 2008

The CD4/CD8 lineage choice: new insights into epigenetic regulation during T cell development

scientific article published on January 2004

The Prevotella copri Complex Comprises Four Distinct Clades Underrepresented in Westernized Populations

scientific article published on 10 October 2019

The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease

scientific journal article

The SDF-1/CXCR4 pathway and the development of the cerebellar system

scientific journal article

The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium

The chemokine SDF1 regulates migration of dentate granule cells

scientific article (publication date: September 2002)

The chemokine SDF1/CXCL12 and its receptor CXCR4 regulate mouse germ cell migration and survival

scientific journal article

The chemokine stromal cell-derived factor-1 promotes the survival of embryonic retinal ganglion cells.

scientific article published on June 2003

The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat

scientific article

The epigenetic landscape of lineage choice: lessons from the heritability of CD4 and CD8 expression

scientific article

The functional impact of the intestinal microbiome on mucosal immunity and systemic autoimmunity

scientific article published on July 2015

The genome of th17 cell-inducing segmented filamentous bacteria reveals extensive auxotrophy and adaptations to the intestinal environment

scientific article

The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells

scientific article published on 11 April 2019

The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy ⬇️

scientific article published on May 4, 2011

The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring

scientific article

The microbiome in infectious disease and inflammation

scientific article published on 6 January 2012

The microbiota in adaptive immune homeostasis and disease

scientific article

The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system

scientific article published in May 2006

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

scientific article (publication date: 22 September 2006)

The role of CXCR4 in maintaining peripheral B cell compartments and humoral immunity

scientific article published on November 2004

The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells

The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells.

scientific article

The role of the nuclear hormone receptor RORγt in the development of lymph nodes and Peyer's patches

scientific article (publication date: October 2003)

Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells

scientific article

Transcription factor AP4 modulates reversible and epigenetic silencing of the Cd4 gene ⬇️

scientific article published on August 22, 2011

Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells

scientific article

Transcriptional regulation of Th17 cell differentiation

scientific article

Transcriptional regulatory networks in Th17 cell differentiation

scientific article published on 26 March 2009

Translating microbiome futures

scientific article published on 01 November 2018

Virus-host interactions: new insights from the small RNA world.

scientific article

Visualization of mucosal homeostasis via single- and multiphoton intravital fluorescence microscopy

scientific article

c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont

scientific article published on 7 February 2018

miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation

scientific article

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