List of works by Palle Serup

A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo.

scientific article published on 20 May 2015

A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells.

scientific article published on 07 April 2009

A step closer to making beta cells.

scientific article published on 13 January 2012

Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development

scientific journal article

An illustrated review of early pancreas development in the mouse.

scientific article

An improved method for three-dimensional reconstruction of protein expression patterns in intact mouse and chicken embryos and organs.

scientific article published on 3 May 2007

Analysis of pancreatic endocrine development in GDF11-deficient mice

scientific article

Arx and Nkx2.2 compound deficiency redirects pancreatic alpha- and beta-cell differentiation to a somatostatin/ghrelin co-expressing cell lineage

scientific article

Bulking Up on Beta Cells

scientific article published on 01 August 2013

Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development

scientific article published on 28 May 2020

Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents.

scholarly article

EVEN-SKIPPED HOMEOBOX 1 controls human ES cell differentiation by directly repressing GOOSECOID expression.

scientific article

Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression.

scientific article published on April 2007

Embryonic stem cell-based diabetes therapy--a long road to travel.

scientific article

Endodermal expression of Nkx6 genes depends differentially on Pdx1.

scientific article published on 16 November 2005

Engineering artificial signaling centers to polarize embryoid body differentiation

scientific article published on 29 September 2011

Expression and misexpression of members of the FGF and TGFbeta families of growth factors in the developing mouse pancreas

scientific article published in April 2003

Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation.

scientific article published in November 2002

Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme.

scientific article published on 8 October 2010

Generation and characterization of monoclonal antibodies against the transcription factor Nkx6.1.

scientific article

Generation of animals allowing the conditional inactivation of the Pax4 gene.

scientific article published on 21 June 2012

Immunohistochemistry of pancreatic development in cattle and pig

scientific article published on 01 April 2010

Investigation and characterization of the duct cell-enriching process during serum-free suspension and monolayer culture using the human exocrine pancreas fraction.

scientific article published in January 2009

Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice

scientific journal article

Mesenchymal bone morphogenetic protein signaling is required for normal pancreas development.

scientific article published on 3 June 2010

Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling

scientific article published on 07 February 2022

Mind bomb 1 is required for pancreatic β-cell formation

scientific journal article

Neurog3-dependent pancreas dysgenesis causes ectopic pancreas in Hes1 mutant mice

scientific article published on 03 September 2018

Opposing actions of Arx and Pax4 in endocrine pancreas development ⬇️

scientific article published on October 15, 2003

Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice

scientific article published on 10 August 2012

Permanent Neonatal Diabetes and Enteric Anendocrinosis Associated With Biallelic Mutations in NEUROG3. ⬇️

scientific article

Preservation of proliferating pancreatic progenitor cells by Delta-Notch signaling in the embryonic chicken pancreas

scientific article

Retinoic Acid Synthesis Promotes Development of Neural Progenitors from Mouse Embryonic Stem Cells by Suppressing Endogenous, Wnt-Dependent Nodal Signaling ⬇️

scientific article published on September 1, 2010

Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis

scientific article

Specifying pancreatic endocrine cell fates.

scientific article published on 25 May 2006

Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function

scientific article published on June 2009

The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube

scientific journal article

The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

scientific article

The role of Brn4/Pou3f4 and Pax6 in forming the pancreatic glucagon cell identity

scientific journal article

The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas

scientific journal article

The transcriptional activity of Neurog3 affects migration and differentiation of ectopic endocrine cells in chicken endoderm.

scientific article published on July 2010

Three-dimensional localisation of NANOG, OCT4, and E-CADHERIN in porcine pre- and peri-implantation embryos

scientific article published on 01 January 2011

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