List of works - Bart Lenselink

A covalent antagonist for the human adenosine A2A receptor

scientific article published on 3 December 2016

A yeast screening method to decipher the interaction between the adenosine A2B receptor and the C-terminus of different G protein α-subunits

scientific article

Application of portfolio optimization to drug discovery

scientific article

Beyond the hype: deep neural networks outperform established methods using a ChEMBL bioactivity benchmark set.

scientific article published on 14 August 2017

Discovery and mapping of an intracellular antagonist binding site at the chemokine receptor CCR2.

scientific article

Domains for activation and inactivation in G protein-coupled receptors--a mutational analysis of constitutive activity of the adenosine A2B receptor

scientific article

Getting from A to B-exploring the activation motifs of the class B adhesion G protein-coupled receptor subfamily G member 4/GPR112.

scientific article published on 28 January 2016

In search of novel ligands using a structure-based approach: a case study on the adenosine A2A receptor

scientific article (publication date: October 2016)

Interacting with GPCRs: Using Interaction Fingerprints for Virtual Screening

scientific article published on 24 October 2016

Large-Scale Modeling of Sparse Protein Kinase Activity Data

scientific article published on 9 June 2023

Proteochemometric modeling in a Bayesian framework

scientific article published on 28 June 2014

Relative Binding Free Energy Calculations Applied to Protein Homology Models

scientific article published on 18 November 2016

Removal of human ether-à-go-go related gene (hERG) K+ channel affinity through rigidity: a case of clofilium analogues

scientific article

Scanning mutagenesis in a yeast system delineates the role of the NPxxY(x)(5,6)F motif and helix 8 of the adenosine A(2B) receptor in G protein coupling

scientific article

Selecting an optimal number of binding site waters to improve virtual screening enrichments against the adenosine A2A receptor

scientific article published on 3 June 2014

Structure-Affinity Relationships and Structure-Kinetic Relationships of 1,2-Diarylimidazol-4-carboxamide Derivatives as Human Cannabinoid 1 Receptor Antagonists

scientific article published on 7 November 2017

Structure-Affinity Relationships and Structure-Kinetics Relationships of Pyrido[2,1-f]purine-2,4-dione Derivatives as Human Adenosine A3 Receptor Antagonists

scientific article published on 14 August 2017

Synthesis and evaluation of N-substituted 2-amino-4,5-diarylpyrimidines as selective adenosine A1 receptor antagonists

scientific article published on 26 September 2016

List of works by Bart Lenselink

A covalent antagonist for the human adenosine A2A receptor

A yeast screening method to decipher the interaction between the adenosine A2B receptor and the C-terminus of different G protein α-subunits

Application of portfolio optimization to drug discovery

Beyond the hype: deep neural networks outperform established methods using a ChEMBL bioactivity benchmark set.

Discovery and mapping of an intracellular antagonist binding site at the chemokine receptor CCR2.

Domains for activation and inactivation in G protein-coupled receptors--a mutational analysis of constitutive activity of the adenosine A2B receptor

Getting from A to B-exploring the activation motifs of the class B adhesion G protein-coupled receptor subfamily G member 4/GPR112.

In search of novel ligands using a structure-based approach: a case study on the adenosine A2A receptor

Interacting with GPCRs: Using Interaction Fingerprints for Virtual Screening

Large-Scale Modeling of Sparse Protein Kinase Activity Data

Proteochemometric modeling in a Bayesian framework

Relative Binding Free Energy Calculations Applied to Protein Homology Models

Removal of human ether-à-go-go related gene (hERG) K+ channel affinity through rigidity: a case of clofilium analogues

Scanning mutagenesis in a yeast system delineates the role of the NPxxY(x)(5,6)F motif and helix 8 of the adenosine A(2B) receptor in G protein coupling

Selecting an optimal number of binding site waters to improve virtual screening enrichments against the adenosine A2A receptor

Structure-Affinity Relationships and Structure-Kinetic Relationships of 1,2-Diarylimidazol-4-carboxamide Derivatives as Human Cannabinoid 1 Receptor Antagonists

Structure-Affinity Relationships and Structure-Kinetics Relationships of Pyrido[2,1-f]purine-2,4-dione Derivatives as Human Adenosine A3 Receptor Antagonists

Synthesis and evaluation of N-substituted 2-amino-4,5-diarylpyrimidines as selective adenosine A1 receptor antagonists