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List of works by Christopher Lear

A working model for hypothermic neuroprotection.

scientific article published on 16 April 2018

An investigation of fetal behavioural states during maternal sleep in healthy late gestation pregnancy: an observational study

scientific article

Analgesics, sedatives, anticonvulsant drugs, and the cooled brain.

scientific article

Antenatal dexamethasone before asphyxia promotes cystic neural injury in preterm fetal sheep by inducing hyperglycemia

scientific article published in January 2017

Biphasic changes in fetal heart rate variability in preterm fetal sheep developing hypotension after acute on chronic lipopolysaccharide exposure

scientific article published on 18 June 2014

Cholinergic and β-adrenergic control of cardiovascular reflex responses to brief repeated asphyxia in term-equivalent fetal sheep

scientific article

Chronic inflammation and impaired development of the preterm brain.

scientific article published on 26 November 2017

Complex interactions between hypoxia-ischemia and inflammation in preterm brain injury.

scientific article published in December 2017

Computer-based intrapartum fetal monitoring and beyond: a review of the 2 Workshop on Signal Processing and Monitoring in Labor (Oct 2017, Oxford UK)

scientific article published on 18 June 2019

Connexin hemichannel blockade improves survival of striatal GABA-ergic neurons after global cerebral ischaemia in term-equivalent fetal sheep.

scientific article published on 24 July 2017

Deceleration area and capacity during labour-like umbilical cord occlusions identify evolving hypotension: a controlled study in fetal sheep

scientific article published on 28 December 2020

Delayed intranasal infusion of human amnion epithelial cells improves white matter maturation after asphyxia in preterm fetal sheep.

scientific article published in January 2017

EEG sharp waves are a biomarker of striatal neuronal survival after hypoxia-ischemia in preterm fetal sheep

scientific article published in Scientific Reports

Early sinusoidal heart rate patterns and heart rate variability to assess hypoxia-ischaemia in near-term fetal sheep

scientific article published on 10 October 2019

Effect of maternal position on fetal behavioural state and heart rate variability in healthy late gestation pregnancy

scientific article published on 21 November 2016

Evolving changes in fetal heart rate variability and brain injury after hypoxia-ischaemia in preterm fetal sheep

scientific article published on 8 January 2018

In the Era of Therapeutic Hypothermia, How Well Do Studies of Perinatal Neuroprotection Control Temperature?

scientific article published on 17 December 2016

Magnesium is not consistently neuroprotective for perinatal hypoxia-ischemia in term-equivalent models in preclinical studies: a systematic review

scientific article published on January 2014

Magnesium sulfate and sex differences in cardiovascular and neural adaptations during normoxia and asphyxia in preterm fetal sheep

scientific article published on 21 March 2018

Magnesium sulfate reduces EEG activity but is not neuroprotective after asphyxia in preterm fetal sheep.

scientific article published on 17 June 2016

Magnesium sulphate and cardiovascular and cerebrovascular adaptations to asphyxia in preterm fetal sheep

scientific article

Magnetic Resonance Imaging Correlates of White Matter Gliosis and Injury in Preterm Fetal Sheep Exposed to Progressive Systemic Inflammation

scientific article published on 24 November 2020

Peripheral chemoreflex control of fetal heart rate decelerations overwhelms the baroreflex during brief umbilical cord occlusions in fetal sheep

scientific article published on 23 July 2020

Plasma vasopressin levels are closely associated with fetal hypotension and neuronal injury after hypoxia-ischemia in near-term fetal sheep

scientific article published on 17 March 2020

Potential neuroprotective strategies for perinatal infection and inflammation

scientific article published on 19 February 2015

Protection of axonal integrity with 48 or 72 h of cerebral hypothermia in near-term fetal sheep

scientific article published on 24 June 2019

Reply from Christopher A. Lear, Robert Galinsky, Guido Wassink, Kyohei Yamaguchi, Joanne O. Davidson, Jenny A. Westgate, Laura Bennet and Alistair J. Gunn

scientific article

Reply to the "Letter to the Editor: Mind the gap: epistemology of heart rate variability"

scientific article published on 01 September 2020

Subclinical decelerations during developing hypotension in preterm fetal sheep after acute on chronic lipopolysaccharide exposure.

scientific article

Sympathetic neural activation does not mediate heart rate variability during repeated brief umbilical cord occlusions in near-term fetal sheep

scientific article published on 10 April 2015

Synergistic white matter protection with acute-on-chronic endotoxin and subsequent asphyxia in preterm fetal sheep

scientific article

The Effect of Size, Maturation, Global Asphyxia, Cerebral Ischemia, and Therapeutic Hypothermia on the Pharmacokinetics of High-Dose Recombinant Erythropoietin in Fetal Sheep

scientific article published on 25 April 2020

The effects of dexamethasone on post-asphyxial cerebral oxygenation in the preterm fetal sheep.

scientific article published on 10 November 2014

The fetus at the tipping point: modifying the outcome of fetal asphyxia

scientific article published on 21 June 2018

The myths and physiology surrounding intrapartum decelerations: the critical role of the peripheral chemoreflex.

scientific article

The peripheral chemoreflex: indefatigable guardian of fetal physiological adaptation to labour

scientific article published on 31 March 2018

Time and sex dependent effects of magnesium sulphate on post-asphyxial seizures in preterm fetal sheep

scientific article published on 23 March 2018

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