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List of works by Jason Wong

A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening

scientific article published on 18 October 2018

A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients.

scientific article

A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network.

scientific article published on 06 September 2016

A tumor microenvironment-specific gene expression signature predicts chemotherapy resistance in colorectal cancer patients

scientific article published on 12 February 2021

Activity profiling of platelets by chemical proteomics.

scientific article published in January 2009

An investigation of the potential for epigenetic inactivation by transcription read-through in a sporadic colorectal cancer

scientific article published on 22 March 2016

Analysis of 7,815 cancer exomes reveals associations between mutational processes and somatic driver mutations

scientific article published on 09 November 2018

Application of fast Fourier transform cross-correlation for the alignment of large chromatographic and spectral datasets.

scientific article published in September 2005

Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr ⬇️

scientific article published on February 2016

Beta 2 glycoprotein I is a substrate of thiol oxidoreductases

scientific article published on 01 September 2010

Bioinformatics analysis reveals biophysical and evolutionary insights into the 3-nitrotyrosine post-translational modification in the human proteome ⬇️

scientific article published on February 6, 2013

Bioorthogonal labelling of 3-nitrotyrosine in peptides and proteins through diazotisation mediated azidation

scientific article published on 24 November 2014

BloodChIP: a database of comparative genome-wide transcription factor binding profiles in human blood cells

scientific article published on 31 October 2013

Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression

scientific article

Computational methods for the comparative quantification of proteins in label-free LCn-MS experiments.

scientific article published on 28 September 2007

Control of blood proteins by functional disulfide bonds.

scientific article published on 12 February 2014

Control of mature protein function by allosteric disulfide bonds.

scientific article published on 28 October 2010

Deterministic projection by growing cell structure networks for visualization of high-dimensionality datasets.

scientific article published on 5 March 2005

Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes

scientific article published in Nature

Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells

scientific article

Disruption of a -35 kb Enhancer Impairs CTCF Binding and Expression in Colorectal Cells

scientific article published on 13 June 2018

Disulfide bond acquisition through eukaryotic protein evolution.

scientific article

Disulfide bond that constrains the HIV-1 gp120 V3 domain is cleaved by thioredoxin

scientific article

Dual roles of different redox forms of complement factor H in protecting against age related macular degeneration

scientific article published on 22 September 2018

ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer.

scientific article published on 2 May 2011

Epigenetic inactivation of the candidate tumor suppressor USP44 is a frequent and early event in colorectal neoplasia

scientific article published on 16 May 2014

Factor XI is a substrate for oxidoreductases: enhanced activation of reduced FXI and its role in antiphospholipid syndrome thrombosis

scientific article published on 13 June 2012

Finding cancer driver mutations in the era of big data research.

scientific article published on 2 April 2018

FluClass: A novel algorithm and approach to score and visualize the phylogeny of the influenza virus using mass spectrometry

scientific article

FluShuffle and FluResort: new algorithms to identify reassorted strains of the influenza virus by mass spectrometry ⬇️

scientific article published on August 20, 2012

Functional Mutations Form at CTCF-Cohesin Binding Sites in Melanoma Due to Uneven Nucleotide Excision Repair across the Motif

scientific article published on December 2016

Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes.

scientific article published on 23 August 2013

Grouping of visual objects by honeybees

scientific article published in September 2004

Identification of allosteric disulfides from labile bonds in X-ray structures.

scientific article published on 7 February 2018

Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes

scientific article published on 23 August 2016

JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma

scientific article published on 25 July 2019

Lateral self-association of VWF involves the Cys2431-Cys2453 disulfide/dithiol in the C2 domain

Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic Leukemia

scientific article published on 01 December 2018

MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation.

scientific article

MMSAT: Automated Quantification of Metabolites in Selected Reaction Monitoring Experiments ⬇️

scientific article published on December 13, 2011

Mass and relative elution time profiling: two-dimensional analysis of sphingolipids in Alzheimer's disease brains.

scientific article published in August 2011

Mass trees: a new phylogenetic approach and algorithm to chart evolutionary history with mass spectrometry.

scientific article published on 21 May 2013

Mechanism of dimerization of a recombinant mature vascular endothelial growth factor C

scientific article published on 26 December 2013

Menin “reads” H3K79me2 mark in a nucleosomal context

scientific article published on 16 February 2023

Mutation hotspots in cis-regulatory regions in cancer

scientific article published on 23 November 2016

Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer

scientific article published on 03 February 2020

Nitration of tyrosines in complement factor H domains alters its immunological activity and mediates a pathogenic role in age related macular degeneration

scientific article published on February 2017

Noninvasive imaging of cell death using an Hsp90 ligand

scientific article published on 15 February 2011

OncoCis: annotation of cis-regulatory mutations in cancer

scientific article

Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells

scientific article published on 21 October 2014

Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias

scientific article

PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells.

scientific article published on 4 April 2016

Performance of the computer algorithm COMPLX for the detection of protein complexes in the mass spectra of simulated biological mixtures.

scientific article published in September 2005

Photochemical and electrophysical production of radicals on millisecond timescales to probe the structure, dynamics and interactions of proteins.

scientific article published on 28 May 2004

Phylogenetic Analysis Using Protein Mass Spectrometry

scientific article published on January 2017

Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples.

scientific article published on 27 September 2017

Redox control of β2-glycoprotein I-von Willebrand factor interaction by thioredoxin-1 ⬇️

scientific article published on August 1, 2010

Redox regulation of methionine aminopeptidase 2 activity

scientific article

Reduced nuclear DNA methylation and mitochondrial transcript changes in adenomas do not associate with mtDNA methylation

scientific article published on 29 December 2018

Repurposing Azacitidine and Carboplatin to Prime Immune Checkpoint Blockade–resistant Melanoma for Anti-PD-L1 Rechallenge

scientific article published in 2022

Signal analysis for genome-wide maps of histone modifications measured by ChIP-seq.

scientific article published on 17 February 2012

Signature peptides of influenza nucleoprotein for the typing and subtyping of the virus by high resolution mass spectrometry.

scientific article published on 11 September 2009

Single nucleotide polymorphism array profiling identifies distinct chromosomal aberration patterns across colorectal adenomas and carcinomas

scientific article

SpecAlign--processing and alignment of mass spectra datasets.

scientific article published on 2 February 2005

Study of the Ribonuclease−S-Protein−Peptide Complex Using a Radical Probe and Electrospray Ionization Mass Spectrometry ⬇️

scientific article published on April 1, 2003

Systematic Screening of Promoter Regions Pinpoints Functional Cis-Regulatory Mutations in a Cutaneous Melanoma Genome

scientific article

The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes.

scientific article published on 22 May 2017

The non-coding RNA landscape of human hematopoiesis and leukemia.

scientific article

The search for cis-regulatory driver mutations in cancer genomes

scientific article

Typing of human and animal strains of influenza virus with conserved signature peptides of matrix M1 protein by high resolution mass spectrometry.

scientific article

Tyrosine nitration moderates the peptidase activity of human methionyl aminopeptidase 2.

scientific article

msmsEval: tandem mass spectral quality assignment for high-throughput proteomics.

scientific article

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