List of works - Fabio Moda

Biosafety of Prions

scientific article published on 2 August 2017

Brain delivery of AAV9 expressing an anti-PrP monovalent antibody delays prion disease in mice.

scientific article

Chronic wasting disease and atypical forms of bovine spongiform encephalopathy and scrapie are not transmissible to mice expressing wild-type levels of human prion protein.

scientific article published on 11 April 2012

Clinical and neuropathological phenotype associated with the novel V189I mutation in the prion protein gene

article

Contributions of Molecular and Optical Techniques to the Clinical Diagnosis of Alzheimer's Disease

scientific article published on 03 November 2020

Defined α-synuclein prion-like molecular assemblies spreading in cell culture

scientific article

Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia

scientific article

Detection of prions in blood from patients with variant Creutzfeldt-Jakob disease

scientific article published on December 2016

Diagnostic Accuracy of Prion Disease Biomarkers in Iatrogenic Creutzfeldt-Jakob Disease

scientific article published on 12 February 2020

Differential overexpression of SERPINA3 in human prion diseases

scientific article published on 15 November 2017

Effects of peptidyl-prolyl isomerase 1 depletion in animal models of prion diseases.

scientific article published in March 2018

Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson's disease and multiple system atrophy

scientific article published on 08 August 2019

Grass plants bind, retain, uptake, and transport infectious prions

scientific article

Halogenation of the N-Terminus Tyrosine 10 Promotes Supramolecular Stabilization of the Amyloid-β Sequence 7-12

scientific article published on 25 February 2020

Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases

scientific article published on 22 January 2018

High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions.

scientific article published on 6 September 2017

Infectivity in skeletal muscle of cattle with atypical bovine spongiform encephalopathy.

scientific article

Investigating the Molecular Basis of the Aggregation Propensity of the Pathological D76N Mutant of Beta-2 Microglobulin: Role of the Denatured State

scientific article published on 18 January 2019

MM2-thalamic Creutzfeldt-Jakob disease: neuropathological, biochemical and transmission studies identify a distinctive prion strain.

scientific article published on 21 February 2012

MRI abnormalities found 1 year prior to symptom onset in a case of Creutzfeldt-Jakob disease

scientific article published on 12 February 2016

Molecular subtypes of Alzheimer's disease.

scientific article published on 19 February 2018

Neuropathology of the recessive A673V APP mutation: Alzheimer disease with distinctive features.

scientific article published on 15 September 2010

Novel screening approaches for human prion diseases drug discovery

scientific article published on 04 July 2019

PMCA-replicated PrPD in urine of vCJD patients maintains infectivity and strain characteristics of brain PrPD: Transmission study

article

Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model

scientific journal article

Prions Strongly Reduce NMDA Receptor S-Nitrosylation Levels at Pre-symptomatic and Terminal Stages of Prion Diseases

scientific article published on 01 February 2019

Prions in the urine of patients with variant Creutzfeldt-Jakob disease

scientific article

Protein Misfolding Cyclic Amplification of Infectious Prions

scientific article published on 31 July 2017

Sporadic MM-1 Type Creutzfeldt-Jakob Disease With Hemiballic Presentation and No Cognitive Impairment Until Death: How New NCJDRSU Diagnostic Criteria May Allow Early Diagnosis

scientific article published on 05 September 2018

Strain-dependent profile of misfolded prion protein aggregates

scientific article published on 15 February 2016

Synthetic Prion Selection and Adaptation

scientific article published on 03 August 2018

Synthetic prions and other human neurodegenerative proteinopathies.

scientific article

Synthetic prions with novel strain-specified properties

scientific article

Tackling amyloidogenesis in Alzheimer's disease with A2V variants of Amyloid-β.

scientific article published on 11 February 2016

Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors

article

The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo

scientific article published on 23 March 2017

The Prion Concept and Synthetic Prions.

scientific article published on 20 July 2017

The cognitive phenotypes of Creutzfeldt-Jakob disease: comparison with secondary metabolic encephalopathy

scientific article published on 28 January 2022

Treatment with a non-toxic, self-replicating anti-prion delays or prevents prion disease in vivo.

scientific article published on 20 June 2017

Use of different RT-QuIC substrates for detecting CWD prions in the brain of Norwegian cervids

scientific article published on 09 December 2019

α-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication.

scientific article published on 30 August 2017

List of works by Fabio Moda

Biosafety of Prions

Brain delivery of AAV9 expressing an anti-PrP monovalent antibody delays prion disease in mice.

Chronic wasting disease and atypical forms of bovine spongiform encephalopathy and scrapie are not transmissible to mice expressing wild-type levels of human prion protein.

Clinical and neuropathological phenotype associated with the novel V189I mutation in the prion protein gene

Contributions of Molecular and Optical Techniques to the Clinical Diagnosis of Alzheimer's Disease

Defined α-synuclein prion-like molecular assemblies spreading in cell culture

Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia

Detection of prions in blood from patients with variant Creutzfeldt-Jakob disease

Diagnostic Accuracy of Prion Disease Biomarkers in Iatrogenic Creutzfeldt-Jakob Disease

Differential overexpression of SERPINA3 in human prion diseases

Effects of peptidyl-prolyl isomerase 1 depletion in animal models of prion diseases.

Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson's disease and multiple system atrophy

Grass plants bind, retain, uptake, and transport infectious prions

Halogenation of the N-Terminus Tyrosine 10 Promotes Supramolecular Stabilization of the Amyloid-β Sequence 7-12

Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases

High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions.

Infectivity in skeletal muscle of cattle with atypical bovine spongiform encephalopathy.

Investigating the Molecular Basis of the Aggregation Propensity of the Pathological D76N Mutant of Beta-2 Microglobulin: Role of the Denatured State

MM2-thalamic Creutzfeldt-Jakob disease: neuropathological, biochemical and transmission studies identify a distinctive prion strain.

MRI abnormalities found 1 year prior to symptom onset in a case of Creutzfeldt-Jakob disease

Molecular subtypes of Alzheimer's disease.

Neuropathology of the recessive A673V APP mutation: Alzheimer disease with distinctive features.

Novel screening approaches for human prion diseases drug discovery

PMCA-replicated PrPD in urine of vCJD patients maintains infectivity and strain characteristics of brain PrPD: Transmission study

Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model

Prions Strongly Reduce NMDA Receptor S-Nitrosylation Levels at Pre-symptomatic and Terminal Stages of Prion Diseases

Prions in the urine of patients with variant Creutzfeldt-Jakob disease

Protein Misfolding Cyclic Amplification of Infectious Prions

Sporadic MM-1 Type Creutzfeldt-Jakob Disease With Hemiballic Presentation and No Cognitive Impairment Until Death: How New NCJDRSU Diagnostic Criteria May Allow Early Diagnosis

Strain-dependent profile of misfolded prion protein aggregates

Synthetic Prion Selection and Adaptation

Synthetic prions and other human neurodegenerative proteinopathies.

Synthetic prions with novel strain-specified properties

Tackling amyloidogenesis in Alzheimer's disease with A2V variants of Amyloid-β.

Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors

The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo

The Prion Concept and Synthetic Prions.

The cognitive phenotypes of Creutzfeldt-Jakob disease: comparison with secondary metabolic encephalopathy

Treatment with a non-toxic, self-replicating anti-prion delays or prevents prion disease in vivo.

Use of different RT-QuIC substrates for detecting CWD prions in the brain of Norwegian cervids

α-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication.