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List of works by Thomas Weber

A calsequestrin cis-regulatory motif coupled to a cardiac troponin T promoter improves cardiac AAV9 transduction specificity.

scientific article published on 15 March 2018

A putative link between exocytosis and tumor development

scientific article published on 01 December 2002

AAV Vectors for Efficient Gene Delivery to Rodent Hearts

scientific article published on 01 January 2019

Adeno-associated virus 2 infection requires endocytosis through the CLIC/GEEC pathway.

scientific article published on December 2011

Altering AAV tropism with mosaic viral capsids

scientific article published in June 2005

Alternatively spliced tissue factor promotes plaque angiogenesis through the activation of hypoxia-inducible factor-1α and vascular endothelial growth factor signaling

scientific article

Cardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failure

scientific article

Cardiac gene therapy with adeno-associated virus-based vectors.

scientific article published on 4 February 2017

Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors

scientific article published in July 2000

Concomitant Intravenous Nitroglycerin With Intracoronary Delivery of AAV1.SERCA2a Enhances Gene Transfer in Porcine Hearts ⬇️

scientific article published on January 3, 2012

Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs. ⬇️

scientific article published on October 1999

Do we need marker gene studies in humans to improve clinical AAV gene therapy?

scientific article published on 5 January 2017

Effect of bortezomib on the efficacy of AAV9.SERCA2a treatment to preserve cardiac function in a rat pressure-overload model of heart failure.

scientific article published on 27 February 2014

Effect of inhibition of dynein function and microtubule-altering drugs on AAV2 transduction.

scientific article published on 22 June 2007

Effectiveness of gene delivery systems for pluripotent and differentiated cells.

scientific article published on 18 February 2015

Expressing Transgenes That Exceed the Packaging Capacity of Adeno-Associated Virus Capsids

scientific article published on 12 January 2016

Functional architecture of an intracellular membrane t-SNARE

scientific article published in Nature

Gene therapy for heart failure

scientific article published on 01 March 2012

Gene therapy: charting a future course--summary of a National Institutes of Health Workshop, April 12, 2013.

scientific article

High capsid-genome correlation facilitates creation of AAV libraries for directed evolution

scientific article

Human Cardiac Gene Therapy

article

Identification of functional domains in the cytoskeletal protein talin

scientific article published on 01 September 1994

Insertion of filamin into lipid membranes examined by calorimetry, the film balance technique, and lipid photolabeling

scientific article published on 01 October 1994

Intracellular transport of recombinant adeno-associated virus vectors ⬇️

scientific article published on February 23, 2012

Liposome fusion assay to monitor intracellular membrane fusion machines

scientific article published on 01 January 2003

Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models

scientific article published on 13 September 2011

Pre-existing anti-adeno-associated virus antibodies as a challenge in AAV gene therapy

scientific article published on 03 April 2013

Production and Characterization of Vectors Based on the Cardiotropic AAV Serotype 9.

scientific article

Protein Phosphatase Inhibitor-1 Gene Therapy in a Swine Model of Nonischemic Heart Failure.

scientific article published on October 2017

Protein S Protects against Podocyte Injury in Diabetic Nephropathy

scientific article published on 6 March 2018

Quantification of AAV particle titers by infrared fluorescence scanning of coomassie-stained sodium dodecyl sulfate-polyacrylamide gels.

scientific article

Rapid and efficient fusion of phospholipid vesicles by the alpha-helical core of a SNARE complex in the absence of an N-terminal regulatory domain

scientific article published on October 1999

Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs.

scientific article published on 25 March 2004

Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpins

scientific article published on 3 September 2002

Response to 'Run for your life ... at a comfortable speed and not too far'

scientific article published on 01 April 2013

SNAREpins are functionally resistant to disruption by NSF and alphaSNAP.

scientific article

SNAREpins: minimal machinery for membrane fusion

scientific article (publication date: 20 March 1998)

Successful Transduction with AAV Vectors after Selective Depletion of Anti-AAV Antibodies by Immunoadsorption

scientific article published on 21 January 2020

Syntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction

scientific article

Targeted Gene Delivery through the Respiratory System: Rationale for Intratracheal Gene Transfer

article

The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion

scientific article published on 01 September 1999

The myristoyl moiety of myristoylated alanine-rich C kinase substrate (MARCKS) and MARCKS-related protein is embedded in the membrane

scientific article published on 01 August 1995

Use of Adeno-Associated Virus Vector for Cardiac Gene Delivery in Large-Animal Surgical Models of Heart Failure

scientific article

pH-Dependent lytic peptides discovered by phage display

scientific article published in May 2006

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