List of works - Sabine Middendorp

Adult stem cells in the small intestine are intrinsically programmed with their location-specific function

scientific article

An inducible mouse model for microvillus inclusion disease reveals a role for myosin Vb in apical and basolateral trafficking

scientific article

Bruton's Tyrosine Kinase and Phospholipase Cγ2 Mediate Chemokine-Controlled B Cell Migration and Homing

scientific article published on 01 January 2007

Bruton's tyrosine kinase and SLP-65 regulate pre-B cell differentiation and the induction of Ig light chain gene rearrangement.

scientific article

Bruton's tyrosine kinase cooperates with the B cell linker protein SLP-65 as a tumor suppressor in Pre-B cells.

scientific article published on 30 June 2003

Bruton's tyrosine kinase regulates the activation of gene rearrangements at the lambda light chain locus in precursor B cells in the mouse

scientific article

Cellular maturation defects in Bruton's tyrosine kinase-deficient immature B cells are amplified by premature B cell receptor expression and reduced by receptor editing

scientific journal article

Constitutive activation of Bruton's tyrosine kinase induces the formation of autoreactive IgM plasma cells.

scientific article

DGAT2 partially compensates for lipid-induced ER stress in human DGAT1-deficient intestinal stem cells

scientific article published on 17 July 2019

Enhanced Collagen Deposition in the Duodenum of Patients with Hyaline Fibromatosis Syndrome and Protein Losing Enteropathy

scientific article published on 02 November 2020

Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway

scientific article

Function of Bruton's tyrosine kinase during B cell development is partially independent of its catalytic activity.

scientific article published in December 2003

Gene expression analysis of peripheral cells for subclassification of pediatric inflammatory bowel disease in remission

scientific article

Impaired hematopoiesis in mice lacking the transcription factor Sp3

scientific journal article

Impaired precursor B cell differentiation in Bruton's tyrosine kinase-deficient mice.

scientific article published in March 2002

Intestinal epithelial cell polarity defects in disease: lessons from microvillus inclusion disease.

scientific article published on 13 February 2018

Loss of syntaxin 3 causes variant microvillus inclusion disease

scientific article

Many inflammatory bowel disease risk loci include regions that regulate gene expression in immune cells and the intestinal epithelium.

scientific article published on 12 December 2013

Mice deficient for CD137 ligand are predisposed to develop germinal center-derived B-cell lymphoma.

scientific article published on 16 July 2009

Naive T cells in the gut of newly diagnosed, untreated adult patients with inflammatory bowel disease.

scientific article published in November 2014

Novel approaches: Tissue engineering and stem cells--In vitro modelling of the gut.

scientific article published on 15 March 2016

On naivety of T cells in inflammatory bowel disease: a review

scientific article published on January 2015

T cell-derived interferon-γ programs stem cell death in immune-mediated intestinal damage

scientific article published on 01 December 2019

The B cell antigen receptor controls integrin activity through Btk and PLCgamma2.

scientific article published on 10 November 2003

The pre-BCR checkpoint as a cell-autonomous proliferation switch

scientific article published on May 2004

Tumor suppressor function of Bruton tyrosine kinase is independent of its catalytic activity.

scientific article

List of works by Sabine Middendorp

Adult stem cells in the small intestine are intrinsically programmed with their location-specific function

An inducible mouse model for microvillus inclusion disease reveals a role for myosin Vb in apical and basolateral trafficking

Bruton's Tyrosine Kinase and Phospholipase Cγ2 Mediate Chemokine-Controlled B Cell Migration and Homing

Bruton's tyrosine kinase and SLP-65 regulate pre-B cell differentiation and the induction of Ig light chain gene rearrangement.

Bruton's tyrosine kinase cooperates with the B cell linker protein SLP-65 as a tumor suppressor in Pre-B cells.

Bruton's tyrosine kinase regulates the activation of gene rearrangements at the lambda light chain locus in precursor B cells in the mouse

Cellular maturation defects in Bruton's tyrosine kinase-deficient immature B cells are amplified by premature B cell receptor expression and reduced by receptor editing

Constitutive activation of Bruton's tyrosine kinase induces the formation of autoreactive IgM plasma cells.

DGAT2 partially compensates for lipid-induced ER stress in human DGAT1-deficient intestinal stem cells

Enhanced Collagen Deposition in the Duodenum of Patients with Hyaline Fibromatosis Syndrome and Protein Losing Enteropathy

Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway

Function of Bruton's tyrosine kinase during B cell development is partially independent of its catalytic activity.

Gene expression analysis of peripheral cells for subclassification of pediatric inflammatory bowel disease in remission

Impaired hematopoiesis in mice lacking the transcription factor Sp3

Impaired precursor B cell differentiation in Bruton's tyrosine kinase-deficient mice.

Intestinal epithelial cell polarity defects in disease: lessons from microvillus inclusion disease.

Loss of syntaxin 3 causes variant microvillus inclusion disease

Many inflammatory bowel disease risk loci include regions that regulate gene expression in immune cells and the intestinal epithelium.

Mice deficient for CD137 ligand are predisposed to develop germinal center-derived B-cell lymphoma.

Naive T cells in the gut of newly diagnosed, untreated adult patients with inflammatory bowel disease.

Novel approaches: Tissue engineering and stem cells--In vitro modelling of the gut.

On naivety of T cells in inflammatory bowel disease: a review

T cell-derived interferon-γ programs stem cell death in immune-mediated intestinal damage

The B cell antigen receptor controls integrin activity through Btk and PLCgamma2.

The pre-BCR checkpoint as a cell-autonomous proliferation switch

Tumor suppressor function of Bruton tyrosine kinase is independent of its catalytic activity.