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List of works by Masatsugu Ema

"cDNA cloning and predicted primary structure of scalllop sarcoplasmic reticulum Ca(2+)-ATPase" [Comp Biochem Physiol 119B(1998)777-785].

scientific article published in November 1998

Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells

scientific article published on 2 October 2003

Antitumor effects of 2-oxoglutarate through inhibition of angiogenesis in a murine tumor model

scientific article

Arf6 regulates tumour angiogenesis and growth through HGF-induced endothelial β1 integrin recycling

scientific article published on 4 August 2015

Bioluminescence imaging of β cells and intrahepatic insulin gene activity under normal and pathological conditions

scientific article

C1galt1-deficient mice exhibit thrombocytopenia due to abnormal terminal differentiation of megakaryocytes

scientific article

Cell fate decisions in early blood vessel formation

scientific article

Characterization of GATA-1(+) hemangioblastic cells in the mouse embryo

scientific article published on 7 December 2006

Chondroitin sulfate N-acetylgalactosaminyltransferase 1 is necessary for normal endochondral ossification and aggrecan metabolism

scientific journal article

Chromosomal-scale de novo genome assemblies of Cynomolgus Macaque and Common Marmoset

scientific article published in 2021

Combinatorial effects of Flk1 and Tal1 on vascular and hematopoietic development in the mouse

scientific journal article

Compensatory signalling induced in the yolk sac vasculature by deletion of TGFbeta receptors in mice

scientific article published on 20 November 2007

Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche

article

Comprehensive Identification of Krüppel-Like Factor Family Members Contributing to the Self-Renewal of Mouse Embryonic Stem Cells and Cellular Reprogramming

scientific article

Comprehensive evaluation of ubiquitous promoters suitable for the generation of transgenic cynomolgus monkeys†

scientific article published on 01 June 2019

Defective development of secretory neurones in the hypothalamus of Arnt2-knockout mice

scientific journal article

Delayed cutaneous wound healing in Fam129b/Minerva-deficient mice.

scientific article published on 11 September 2012

Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors

scientific article published on 15 September 2005

Developmental regression of hyaloid vasculature is triggered by neurons

scientific article published on 20 June 2016

Distinct expression patterns of Flk1 and Flt1 in the coronary vascular system during development and after myocardial infarction

scientific article published on 17 November 2017

Establishment of macaque trophoblast stem cell lines derived from cynomolgus monkey blastocysts

scientific article published on 22 April 2020

Flk1-GFP BAC Tg mice: an animal model for the study of blood vessel development

scientific article published in January 2010

Flt-1 haploinsufficiency ameliorates muscular dystrophy phenotype by developmentally increased vasculature in mdx mice

scientific article published on 12 August 2010

Flt1 and Flk1 mediate regulation of intraocular pressure and their double heterozygosity causes the buphthalmia in mice

scientific journal article

Fluorescence and Bioluminescence Imaging of Angiogenesis in Flk1-Nano-lantern Transgenic Mice

scientific article

Fluorescent reporter transgenic mice for in vivo live imaging of angiogenesis and lymphangiogenesis

scientific article published on 03 July 2018

Forced expression of Nanog or Esrrb preserves the ESC status in the absence of nucleostemin expression

scientific article

Functional compensation between Myc and PI3K signaling supports self-renewal of embryonic stem cells

scientific article published in March 2015

Generating Vegfr3 reporter transgenic mouse expressing membrane-tagged Venus for visualization of VEGFR3 expression in vascular and lymphatic endothelial cells

scientific article published in PLoS ONE

Generation and characterization of Ins1-cre-driver C57BL/6N for exclusive pancreatic beta cell-specific Cre-loxP recombination

scientific article

Generation of an OCT3/4 reporter cynomolgus monkey ES cell line using CRISPR/Cas9

scientific article published on 15 April 2019

Generation of naive-like porcine-induced pluripotent stem cells capable of contributing to embryonic and fetal development

scientific article published on 9 October 2012

Generation of transgenic cynomolgus monkeys that express green fluorescent protein throughout the whole body

scientific article published on 25 April 2016

Genetic evidence of PEBP2beta-independent activation of Runx1 in the murine embryo

scientific article published on 2 July 2008

Genome-wide identification of endothelial cell-enriched genes in the mouse embryo

scientific journal article

HLF/HIF-2alpha is a key factor in retinopathy of prematurity in association with erythropoietin

scientific article

Heterodimers of bHLH-PAS protein fragments derived from AhR, AhRR, and Arnt prepared by co-expression in Escherichia coli: characterization of their DNA binding activity and preparation of a DNA complex

scientific article

Highly efficient induction of primate iPS cells by combining RNA transfection and chemical compounds

scientific article published on 17 June 2019

In vivo function and evolution of the eutherian-specific pluripotency marker UTF1.

scientific article

Indefinite self-renewal of ESCs through Myc/Max transcriptional complex-independent mechanisms

scientific article published in July 2011

Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia ⬇️

scientific article published on June 23, 1998

Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice

scientific article published on 12 September 2011

Interaction of the nervous system and vascular system is required for the proper assembly of the neocortex

scientific article published on 29 May 2019

Intersection of regulatory pathways controlling hemostasis and hemochorial placentation

scientific article published on 01 December 2021

Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero

scientific article

Klf5 maintains the balance of primitive endoderm versus epiblast specification during mouse embryonic development by suppression of Fgf4.

scientific article

Klf5 suppresses ERK signaling in mouse pluripotent stem cells

scientific article published in PLoS ONE

Klf9 is necessary and sufficient for Purkinje cell survival in organotypic culture

scientific article published on 29 November 2012

Krüppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs

scientific article published in November 2008

Mild impairment of learning and memory in mice overexpressing the mSim2 gene located on chromosome 16: an animal model of Down's syndrome

scientific article (publication date: August 1999)

Molecular basis for Flk1 expression in hemato-cardiovascular progenitors in the mouse

scientific article

Monkeys mutant for PKD1 recapitulate human autosomal dominant polycystic kidney disease

scientific article published on 11 December 2019

Neural retina-specific Aldh1a1 controls dorsal choroidal vascular development via Sox9 expression in retinal pigment epithelial cells.

scientific article published on 3 April 2018

Neurons limit angiogenesis by titrating VEGF in retina

scientific article published on October 2014

Novel ROSA26 Cre-reporter knock-in C57BL/6N mice exhibiting green emission before and red emission after Cre-mediated recombination

scientific article

Osteogenic capillaries orchestrate growth plate-independent ossification of the malleus.

scientific article

Platelet demand modulates the type of intravascular protrusion of megakaryocytes in bone marrow

scientific article

Poor second ovarian stimulation in cynomolgus monkeys (Macaca fascicularis) is associated with the production of antibodies against human follicle-stimulating hormone

scientific article published on 07 March 2019

Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation.

scientific article published on 27 April 2009

Primitive erythropoiesis from mesodermal precursors expressing VE-cadherin, PECAM-1, Tie2, endoglin, and CD34 in the mouse embryo

scientific article published on 22 August 2006

Prox1-GFP/Flt1-DsRed transgenic mice: an animal model for simultaneous live imaging of angiogenesis and lymphangiogenesis

scientific article published on 9 August 2017

RNA content in the nucleolus alters p53 acetylation via MYBBP1A.

scientific article published on 4 February 2011

Rapid isolation of glomeruli coupled with gene expression profiling identifies downstream targets in Pod1 knockout mice

scientific article published on 05 October 2005

Regulation of the ERK signalling pathway in the developing mouse blastocyst

scientific article published on 25 July 2019

Roles of VEGF-A signalling in development, regeneration, and tumours

scientific article published on 16 May 2014

Runx1 is involved in primitive erythropoiesis in the mouse

scientific article

Spatiotemporally Dependent Vascularization Is Differently Utilized among Neural Progenitor Subtypes during Neocortical Development

scientific article published on 01 October 2019

Study of normal and pathological blood vessel morphogenesis in Flt1-tdsRed BAC Tg mice

scientific article published on 26 May 2012

Subventricular zone-derived neural progenitor cells migrate along a blood vessel scaffold toward the post-stroke striatum

scientific article published in March 2010

Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown

scientific article (publication date: 9 February 2017)

The E3 ubiquitin ligase activity of Trip12 is essential for mouse embryogenesis

scientific journal article

The dynamics of revascularization after white matter infarction monitored in Flt1-tdsRed and Flk1-GFP mice

scientific article published on 31 October 2018

The transcription factor Klf5 is essential for intrahepatic biliary epithelial tissue remodeling after cholestatic liver injury.

scientific article published on 9 March 2018

Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor α1 and krüppel-like factor 9 in Purkinje cells

scientific article

Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-β Signaling in Developing Skin Vasculature

scientific article

Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and clock

scientific article

Vascular Endothelial Growth Factor Directly Inhibits Primitive Neural Stem Cell Survival But Promotes Definitive Neural Stem Cell Survival

scientific article published on 01 June 2006

Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival

scientific article published on 25 January 2006

Visualization of endothelial cell cycle dynamics in mouse using the Flt-1/eGFP-anillin system.

scientific article published on 7 February 2018

Visualization of the Epiblast and Visceral Endodermal Cells Using Fgf5-P2A-Venus BAC Transgenic Mice and Epiblast Stem Cells

scientific article

cDNA cloning and predicted primary structure of scallop sarcoplasmic reticulum Ca2+-ATPase ⬇️

scientific article published on April 1, 1998

cDNA cloning and structure of mouse putative Ah receptor

scientific article (publication date: 15 April 1992)

cDNA cloning of a murine homologue of Drosophila single-minded, its mRNA expression in mouse development, and chromosome localization.

scientific article published on January 1996

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