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List of works by Manuel Morales-Ruiz

A small population of liver endothelial cells undergoes endothelial-to-mesenchymal transition in response to chronic liver injury.

scientific article published on 10 August 2017

Adenoviral dominant-negative soluble PDGFRβ improves hepatic collagen, systemic hemodynamics, and portal pressure in fibrotic rats

scientific article published on 20 July 2012

Adipocyte Fatty-Acid Binding Protein is Overexpressed in Cirrhosis and Correlates with Clinical Outcomes

scientific article published on 12 May 2017

Admission B-type natriuretic peptide retains prognostic value in patients with acute coronary syndrome and preserved left ventricular ejection fraction

scientific article published on 26 May 2012

Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells.

scientific article published on 31 May 2001

Akt-mediated foxo1 inhibition is required for liver regeneration.

scientific article published on 16 October 2015

Analysis of a urinary biomarker panel for clinical outcomes assessment in cirrhosis.

scientific article published on 4 June 2015

Antiangiogenic treatment with sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats.

scientific article

Apelin Mediates the Induction of Profibrogenic Genes in Human Hepatic Stellate Cells ⬇️

scientific article published on September 15, 2010

Ascites from cirrhotic patients induces angiogenesis through the phosphoinositide 3-kinase/Akt signaling pathway

scientific article published on 12 April 2005

Cerium Oxide Nanoparticles: Advances in Biodistribution, Toxicity, and Preclinical Exploration

scientific article published on 24 April 2020

Cerium oxide nanoparticles improve liver regeneration after acetaminophen-induced liver injury and partial hepatectomy in rats

scientific article published on 31 October 2019

Characterization of Inflammatory Response in Acute-on-Chronic Liver Failure and Relationship with Prognosis.

scientific article published on 31 August 2016

Chronic blockade of endothelin receptors in cirrhotic rats: Hepatic and hemodynamic effects

scientific article published on 01 January 1999

Circulating CO3-610, a degradation product of collagen III, closely reflects liver collagen and portal pressure in rats with fibrosis.

scientific article

Down the liver sinusoidal endothelial cell (LSEC) hole. Is there a role for lipid rafts in LSEC fenestration?

scientific article published on 21 February 2013

Effect of bacterial lipopolysaccharide on endothelin-1 production in human vascular endothelial cells

scientific article published on 01 January 1997

Effects of alfapump™ system on kidney and circulatory function in patients with cirrhosis and refractory ascites.

scientific article published on 20 March 2017

Enalapril and carvedilol for preventing chemotherapy-induced left ventricular systolic dysfunction in patients with malignant hemopathies: the OVERCOME trial (preventiOn of left Ventricular dysfunction with Enalapril and caRvedilol in patients submi

scientific article published on 10 April 2013

Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates

scientific article

Factors involved in extracellular matrix turnover in human derived cardiomyocytes.

scientific article

Functionalized cerium oxide nanoparticles mitigate the oxidative stress and pro-inflammatory activity associated to the portal vein endothelium of cirrhotic rats

scientific article published on 24 June 2019

Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease

article

Glucocorticoid alternative effects on proliferating and differentiated mammary epithelium are associated to opposite regulation of cell-cycle inhibitor expression.

scientific article published in April 2012

Hepatocarcinoma cells stimulate the growth, migration and expression of pro-angiogenic genes in human hepatic stellate cells

scientific article

Hypoxia and proinflammatory factors upregulate apelin receptor expression in human stellate cells and hepatocytes

scientific article published on 29 March 2011

Hypoxia is an inducer of vasodilator agents in peritoneal macrophages of cirrhotic patients

scientific article published on 01 November 2002

Identification of the potentially arrhythmogenic substrate in the acute phase of ST-segment elevation myocardial infarction.

scientific article published on 16 January 2017

Impaired extracellular matrix degradation in aortic vessels of cirrhotic rats

scientific article published on 13 November 2006

Inactivation of extrahepatic vascular Akt improves systemic hemodynamics and sodium excretion in cirrhotic rats.

scientific article published on 3 August 2010

Increased nitric oxide production in lymphatic endothelial cells causes impairment of lymphatic drainage in cirrhotic rats.

scientific article published on 20 January 2012

Increased renal expression of nitric oxide synthase type III in cirrhotic rats with ascites

scientific article published on 01 May 1998

Influence of caveolin on constitutively activated recombinant eNOS: insights into eNOS dysfunction in BDL rat liver.

scientific article published on 26 June 2003

Inhibition of placental growth factor activity reduces the severity of fibrosis, inflammation, and portal hypertension in cirrhotic mice

scientific article

Lack of a 5.9 kDa peptide C-terminal fragment of fibrinogen α chain precedes fibrosis progression in patients with liver disease

scientific article

Microarray Analysis of Endothelial Differentially Expressed Genes in Liver of Cirrhotic Rats

article

Mir-33 regulates cell proliferation and cell cycle progression.

scientific article published in March 2012

Neutrophil gelatinase-associated lipocalin is a biomarker of acute-on-chronic liver failure and prognosis in cirrhosis

scientific article

Nitric oxide production and inducible nitric oxide synthase expression in peritoneal macrophages of cirrhotic patients

scientific article published on 01 September 1999

Nitric oxide production by peritoneal macrophages of cirrhotic rats: A host response against bacterial peritonitis

scientific article published on 01 June 1997

Nitric oxide synthase 3-dependent vascular remodeling and circulatory dysfunction in cirrhosis

scientific article published on June 2003

Nitric oxide synthase II mRNA expression in cardiac tissue of patients with heart failure undergoing cardiac transplantation

scientific article published on 01 February 2000

Overexpression of angiopoietin-2 in rats and patients with liver fibrosis. Therapeutic consequences of its inhibition

scientific article published on 11 March 2014

Plasma copeptin as biomarker of disease progression and prognosis in cirrhosis.

scientific article published on 12 July 2016

Plasma tissue inhibitor of matrix metalloproteinase-1 (TIMP-1): an independent predictor of poor response to cardiac resynchronization therapy

scientific article

Prevention of chemotherapy-induced left ventricular dysfunction with enalapril and carvedilol: rationale and design of the OVERCOME trial

scientific article published on 06 May 2011

Prevention of fibrosis progression in CCl4-treated rats: role of the hepatic endocannabinoid and apelin systems.

scientific article

Prognosis of new-onset heart failure outpatients and collagen biomarkers

scientific article published on 14 July 2015

Prognostic value of plasma apelin concentrations at admission in patients with ST-segment elevation acute myocardial infarction

scientific article published on 23 November 2016

Regression of fibrosis after chronic stimulation of cannabinoid CB2 receptor in cirrhotic rats.

scientific article

Sipa1l1 is an early biomarker of liver fibrosis in CCl4-treated rats

scientific article

Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting.

scientific article published in May 2001

Systemic inflammation in decompensated cirrhosis: Characterization and role in acute-on-chronic liver failure

scientific article published on 2 August 2016

The Role of Akt in Chronic Liver Disease and Liver Regeneration.

scientific article published on 15 February 2017

The hepatic apelin system: a new therapeutic target for liver disease

scientific article

The loss of DHX15 impairs endothelial energy metabolism, lymphatic drainage and tumor metastasis in mice

scientific article published on 15 October 2021

Urinary neutrophil gelatinase-associated lipocalin predicts kidney outcome and death in patients with cirrhosis and bacterial infections

scientific article published on 5 March 2014

Urine Monocyte Chemoattractant Protein-1 Is an Independent Predictive Factor of Hospital Readmission and Survival in Cirrhosis.

scientific article

Utility of galectin-3 in predicting post-infarct remodeling after acute myocardial infarction based on extracellular volume fraction mapping.

scientific article published on 8 August 2016

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