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List of works by Isabel Santana

A pan-European study of the C9orf72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats

scientific article published on 4 January 2013

Adaptive visual memory reorganization in right medial temporal lobe epilepsy

scientific article published on 28 April 2008

Addition of the Aβ42/40 ratio to the cerebrospinal fluid biomarker profile increases the predictive value for underlying Alzheimer's disease dementia in mild cognitive impairment

scientific article published on 20 March 2018

Adiponectin and sporadic Alzheimer's disease: Clinical and molecular links.

scientific article published on 13 October 2017

Advanced MRI study of migrainous infarction presenting as cortical laminar necrosis - Case report and literature review

scientific article published on 14 February 2018

Alzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-Cog): Normative Data for the Portuguese Population.

scientific article published on 28 February 2018

Amyloid β-induced ER stress is enhanced under mitochondrial dysfunction conditions.

scientific article published on 25 June 2011

Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies

scientific article published on 29 January 2020

Apolipoprotein E epsilon4 allele is a risk factor for Alzheimer's disease: the central region of portugal (Coimbra) as a case study.

scientific article published in January 1999

Association between butyrylcholinesterase and cerebrospinal fluid biomarkers in Alzheimer's disease patients.

scientific article published on 17 January 2017

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

scientific article published on 29 November 2017

Association of HFE common mutations with Parkinson's disease, Alzheimer's disease and mild cognitive impairment in a Portuguese cohort

scientific article

Biparietal variant of Alzheimer's disease: a rare presentation of a common disease

scientific article

CSF Tau proteins reduce misdiagnosis of sporadic Creutzfeldt-Jakob disease suspected cases with inconclusive 14-3-3 result.

scientific article

Cerebrospinal Fluid Total Prion Protein in the Spectrum of Prion Diseases

scientific article published on 30 July 2018

Cerebrospinal fluid Aβ40 is similarly reduced in patients with Frontotemporal Lobar Degeneration and Alzheimer's Disease.

scientific article

Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases

scientific article

Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia

scientific article published on 30 January 2020

Characterization of an FTLD-PDB family with the coexistence of SQSTM1 mutation and hexanucleotide (G₄C₂) repeat expansion in C9orf72 gene

scientific article published on 30 December 2015

Clinical Reasoning: A 55-year-old man with rapidly progressive dementia and parkinsonism.

scientific article published on 9 October 2017

Clock drawing test in mild cognitive impairment: Correlation with cerebral perfusion in single-photon emission computed tomography

scientific article published on 15 April 2019

Cognitive deficits in middle-aged and older adults with bipolar disorder and cognitive complaints: comparison with mild cognitive impairment

scientific article published in June 2009

Cognitive effects of therapy with topiramate in patients with refractory partial epilepsy

scientific article

Comparison of four verbal memory tests for the diagnosis and predictive value of mild cognitive impairment

scientific article

Construct Validity of the Montreal Cognitive Assessment (MoCA).

scientific article

Construct and diagnostic validities of the Free and Cued Selective Reminding Test in the Alzheimer's disease spectrum.

scientific article published on 17 May 2016

Cytochrome c oxidase is decreased in Alzheimer's disease platelets

scientific article published in January 2004

Data mining methods in the prediction of Dementia: A real-data comparison of the accuracy, sensitivity and specificity of linear discriminant analysis, logistic regression, neural networks, support vector machines, classification trees and random fo

scientific article

Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer's disease

scientific article published on 27 April 2017

Diagnostic value of CSF protein profile in a Portuguese population of sCJD patients

scientific article published on 6 May 2009

Differences between Early and Late-Onset Alzheimer's Disease in Neuropsychological Tests

scientific article

Do MCI patients with vitamin B12 deficiency have distinctive cognitive deficits?

scientific article

Does Caffeine Consumption Modify Cerebrospinal Fluid Amyloid-β Levels in Patients with Alzheimer's Disease?

scientific article published in August 2015

Effects of apolipoprotein E genotype on blood lipid composition and membrane platelet fluidity in Alzheimer’s disease

article

Epigenetic regulation of BACE1 in Alzheimer's disease patients and in transgenic mice.

scientific article published on 21 June 2012

Exome sequencing reveals an unexpected genetic cause of disease: NOTCH3 mutation in a Turkish family with Alzheimer's disease

scientific article

Free and Cued Selective Reminding Test is superior to the Wechsler Memory Scale in discriminating mild cognitive impairment from Alzheimer's disease

scientific article published on 20 September 2014

Frontotemporal dementia and mitochondrial DNA transitions

scientific article published in March 2004

Frontotemporal dementia: neuroanatomical correlates of an atypical presentation

scientific article published on 25 July 2014

Genetic Variation of MT-ND Genes in Frontotemporal Lobar Degeneration: Biochemical Phenotype-Genotype Correlation

scientific article published on 3 April 2015

Genetic basis of Alzheimer's dementia: role of mtDNA mutations.

scientific article

Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP

scientific article

Genetic variability in CLU and its association with Alzheimer's disease

scientific article

Genetic variability in SQSTM1 and risk of early-onset Alzheimer dementia: a European early-onset dementia consortium study

scientific article published on 19 February 2015

Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

scientific article published on 15 February 2021

Heritability and genetic variance of dementia with Lewy bodies

scientific article published on 03 April 2019

Impaired processing of 3D motion-defined faces in mild cognitive impairment and healthy aging: an fMRI study

scientific article published on 9 August 2012

Impairment of social cognition in multiple sclerosis: Amygdala atrophy is the main predictor.

scientific article published in December 2016

Increased CSF tau is associated with a higher risk of seizures in patients with Alzheimer's disease

scientific article published on 02 August 2019

Influence of apolipoprotein E genotype on blood redox status of Alzheimer's disease patients

scientific article published in August 1999

Lower CSF Amyloid-Beta1-42 Predicts a Higher Mortality Rate in Frontotemporal Dementia

scientific article published on 25 October 2019

MicroRNA deregulation and chemotaxis and phagocytosis impairment in Alzheimer's disease

scientific article published on 12 December 2015

Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity

scientific article

Mitochondrial DNA variants in a portuguese population of patients with Alzheimer's disease

scientific article

Montreal Cognitive Assessment (MoCA): Normative study for the Portuguese population

scientific article published on July 4, 2011

Montreal Cognitive Assessment (MoCA): validation study for frontotemporal dementia

scientific article published in August 2012

Montreal Cognitive Assessment (MoCA): validation study for vascular dementia

scientific article published on 8 June 2012

Montreal Cognitive Assessment: Influence of Sociodemographic and Health Variables

scientific article published on January 24, 2012

Montreal cognitive assessment: validation study for mild cognitive impairment and Alzheimer disease.

scientific article published in January 2013

Multiple dural arteriovenous fistulas presenting as rapidly progressive dementia

scientific article published in May 2012

Novel progranulin mutation: Screening for PGRN mutations in a Portuguese series of FTD/CBS cases

article

Obesity as a risk factor for Alzheimer's disease: the role of adipocytokines

scientific article published on 20 February 2014

Oxidative damage and progression to Alzheimer's disease in patients with mild cognitive impairment

scientific article published in January 2010

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

scientific article published on 6 April 2015

Peripheral inflammatory cytokines as biomarkers in Alzheimer's disease and mild cognitive impairment

scientific article

Peripheral oxidative damage in mild cognitive impairment and mild Alzheimer's disease.

scientific article

Predicting progression of mild cognitive impairment to dementia using neuropsychological data: a supervised learning approach using time windows.

scientific article

Prediction of long-term (5 years) conversion to dementia using neuropsychological tests in a memory clinic setting

scientific article published on January 2013

Premorbid IQ Influence on Screening Tests’ Scores in Healthy Patients and Patients With Cognitive Impairment

scientific article published on April 12, 2013

Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage

scientific article published on 17 February 2015

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

scientific article published on May 2015

Primary bilateral thalamic astrocytoma presenting with head tremor, ataxia, and dementia

scientific article

Prodromal metabolic phenotype in MCI cybrids: implications for Alzheimer's disease.

scientific article

Progranulin peripheral levels as a screening tool for the identification of subjects with progranulin mutations in a Portuguese cohort

scientific article published on 6 September 2013

Prosopagnosia as the Presenting Symptom of Whipple Disease

scientific article published on June 2016

Pseudohypoparathyroidism type I-b with neurological involvement is associated with a homozygous PTH1R mutation.

scientific article published on 14 July 2016

Psychometric properties of the Montreal Cognitive Assessment (MoCA): an analysis using the Rasch model

scientific article

Rare Variants in PLD3 Do Not Affect Risk for Early-Onset Alzheimer Disease in a European Consortium Cohort

scientific article published on 28 September 2015

Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration

scientific article

Retinal texture biomarkers may help to discriminate between Alzheimer's, Parkinson's, and healthy controls

scientific article published on 21 June 2019

Scaling Cognitive Domains of the Montreal Cognitive Assessment: An Analysis Using the Partial Credit Model

scientific article published on 4 May 2015

Selective Reminding and Free and Cued Selective Reminding in Mild Cognitive Impairment and Alzheimer Disease

scientific article published on 16 September 2015

Serial position effects in Alzheimer's disease, mild cognitive impairment, and normal aging: predictive value for conversion to dementia

scientific article published on 25 June 2012

Severe post-influenza (H1N1) encephalitis involving pulvinar nuclei in an adult patient

scientific article published on 22 October 2015

Single Word Repetition Predicts Long-Term Outcome of Aphasia Caused by an Ischemic Stroke

scientific article published on 11 December 2019

Sporadic Creutzfeldt-Jakob disease causing a 2-years slowly progressive isolated dementia

scientific article

Sporadic Creutzfeldt–Jakob disease diagnostic accuracy is improved by a new CSF ELISA 14-3-3γ assay

scientific article published on 03 March 2016

TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

scientific article published on 23 December 2016

TeLPI performance in subjects with mild cognitive impairment and Alzheimer disease: a validation study.

scientific article published in October 2013

Temporal Integration of 3D Coherent Motion Cues Defining Visual Objects of Unknown Orientation is Impaired in Amnestic Mild Cognitive Impairment and Alzheimer's Disease

scientific article published on January 1, 2012

The Clock Drawing Test: Portuguese Norms, by Age and Education, for Three Different Scoring Systems

scientific article published on March 21, 2013

The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-Costs

scientific article published on March 2015

The Head Turning Sign in Dementia and Mild Cognitive Impairment: Its Relationship to Cognition, Behavior, and Cerebrospinal Fluid Biomarkers

scientific article published on 09 August 2018

The Influence of Adipose Tissue on Brain Development, Cognition, and Risk of Neurodegenerative Disorders.

scientific article

The Portuguese version of Addenbrooke's Cognitive Examination-Revised (ACE-R) in the diagnosis of subcortical vascular dementia and Alzheimer's disease

scientific article published on 28 November 2014

The Portuguese who could no longer speak French: primary progressive aphasia in a bilingual man.

scientific article

The Quadruple Helix-Based Innovation Model of Reference Sites for Active and Healthy Ageing in Europe: The Ageing@Coimbra Case Study.

scientific article

The Relevance of Sociodemographic and Health Variables on MMSE Normative Data

scientific article

The free and cued selective reminding test distinguishes frontotemporal dementia from Alzheimer's disease

scientific article

The free and cued selective reminding test for predicting progression to Alzheimer's disease in patients with mild cognitive impairment: A prospective longitudinal study

scientific article

The free and cued selective reminding test: Validation for mild cognitive impairment and Alzheimer's disease

scientific article published on 03 June 2014

The impact of automated hippocampal volumetry on diagnostic confidence in patients with suspected Alzheimer's disease: A European Alzheimer's Disease Consortium study

scientific article published on 2 March 2017

The inner fluctuations of the brain in presymptomatic Frontotemporal Dementia: The chronnectome fingerprint

scientific article published on 01 February 2019

The neural basis of fatigue in multiple sclerosis: A multimodal MRI approach

scientific article published on 01 December 2018

The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey

scientific article published on 20 August 2014

Theory of Mind and Executive Functions are Dissociated in Multiple Sclerosis

scientific article

Three-Dimensional Face Recognition in Mild Cognitive Impairment: A Psychophysical and Structural MR Study

scientific article published on 13 July 2016

Transthyretin decrease in plasma of MCI and AD patients: investigation of mechanisms for disease modulation

scientific article published in October 2012

Transthyretin stability is critical in assisting beta amyloid clearance- Relevance of transthyretin stabilization in Alzheimer's disease.

scientific article published in June 2017

Validation studies of the Portuguese experimental version of the Montreal Cognitive Assessment (MoCA): confirmatory factor analysis.

scientific article published on 25 November 2009

Validity and Clinical Utility of Different Clock Drawing Test Scoring Systems in Multiple Forms of Dementia

scientific article published on 09 May 2018

Variant Creutzfeldt-Jakob [corrected] disease: the second case in Portugal and in the same geographical region.

scientific article

Whole-exome sequencing reveals PSEN1 and ATP7B combined variants as a possible cause of early-onset Lewy body dementia: a case study of genotype–phenotype correlation

scientific article published in 2022

[Malformations in cortical development in patients with epilepsy. Neuroimaging of 17 cases]

scientific article published on 01 January 2001