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List of works by Isabel R. Orriss

2-Oxothiazolidine-4-carboxylic acid inhibits vascular calcification via induction of glutathione synthesis

scientific article published on 12 September 2020

Acidosis inhibits bone formation by osteoblasts in vitro by preventing mineralization.

scientific article published on 28 July 2005

Acidosis is a key regulator of osteoblast ecto-nucleotidase pyrophosphatase/phosphodiesterase 1 (NPP1) expression and activity

scientific article

Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release.

scientific article

Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation

scientific article published on 8 March 2016

Chronic administration of Glucagon-like peptide-1 receptor agonists improves trabecular bone mass and architecture in ovariectomised mice.

scientific article published on 24 August 2015

Clopidogrel (Plavix), a P2Y12 receptor antagonist, inhibits bone cell function in vitro and decreases trabecular bone in vivo

scientific article published in November 2012

Design and fabrication of 3D-printed anatomically shaped lumbar cage for intervertebral disc (IVD) degeneration treatment.

scientific article published on 19 July 2016

Editorial overview: Musculoskeletal: Where are we with treating musculoskeletal disorders?

scientific article published on 08 April 2016

Extracellular ATP released by osteoblasts is a key local inhibitor of bone mineralisation.

scientific article

Extracellular Nucleotides Regulate Arterial Calcification by Activating Both Independent and Dependent Purinergic Receptor Signaling Pathways

scientific article published on 15 October 2020

Generation of rodent and human osteoblasts.

scientific article

Hypothermia inhibits osteoblast differentiation and bone formation but stimulates osteoclastogenesis.

scientific article published on 4 July 2012

Hypoxia inhibits the growth, differentiation and bone-forming capacity of rat osteoblasts.

scientific article published on 10 March 2006

Hypoxia is a major stimulator of osteoclast formation and bone resorption.

scientific article published in July 2003

Hypoxia stimulates osteoclast formation from human peripheral blood

scientific article published in July 2010

Hypoxia stimulates vesicular ATP release from rat osteoblasts.

scientific article published on July 2009

Inhibition of arterial medial calcification and bone mineralization by extracellular nucleotides: The same functional effect mediated by different cellular mechanisms

scientific article published on 4 October 2017

Inhibition of osteoblast function in vitro by aminobisphosphonates.

scientific article published in January 2009

Inhibition of vascular smooth muscle cell calcification by ATP analogues

scientific article published on 23 July 2019

Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems.

scientific article published on 3 November 2011

Lack of effect of adenosine on the function of rodent osteoblasts and osteoclasts in vitro.

scientific article published on 10 February 2016

Metabolic properties of the osteoclast

scientific article

Mineralisation of collagen rich soft tissues and osteocyte lacunae in Enpp1(-/-) mice.

scientific article published on 28 September 2014

Optimisation of the differing conditions required for bone formation in vitro by primary osteoblasts from mice and rats

scientific article

Osteoblast responses to nucleotides increase during differentiation

scientific article

Purinergic Signaling in Bone ⬇️

scientific article published on May 16, 2013

Purinergic signalling and bone remodelling.

scientific article

Purinergic signalling in osteoblasts.

scientific article published on January 2012

Purinergic signalling in the musculoskeletal system.

scientific article published on 14 August 2013

Pyrophosphate: a key inhibitor of mineralisation.

scientific article published on 7 April 2016

Rat Osteoblast Cultures ⬇️

scientific article published on January 1, 2012

Rodent osteoclast cultures

scientific article published in January 2012

Role of the P2Y13 receptor in the differentiation of bone marrow stromal cells into osteoblasts and adipocytes

scientific article

Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice.

scientific article published on 20 February 2018

Stable sulforaphane protects against gait anomalies and modifies bone microarchitecture in the spontaneous STR/Ort model of osteoarthritis

scientific article published on August 2017

Strontium and osteoblast function

scientific article published on 15 April 2015

Strontium potently inhibits mineralisation in bone-forming primary rat osteoblast cultures and reduces numbers of osteoclasts in mouse marrow cultures

scientific article

The P2X7 Receptor is an Important Regulator of Extracellular ATP Levels ⬇️

scientific article published on March 19, 2012

The P2Y(6) receptor stimulates bone resorption by osteoclasts.

scientific article published on 9 August 2011

The regulation of osteoblast function and bone mineralisation by extracellular nucleotides: The role of p2x receptors.

scientific article published on 26 June 2012

The role of purinergic signalling in the musculoskeletal system

scientific article published on 07 May 2015

Tumour-derived alkaline phosphatase regulates tumour growth, epithelial plasticity and disease-free survival in metastatic prostate cancer.

scientific article published on 22 December 2016

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