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List of works by Pedro P López-Casas

A Tricin Derivative from Deschampsia antarctica Desv. Inhibits Colorectal Carcinoma Growth and Liver Metastasis through the Induction of a Specific Immune Response.

scientific article published on 26 February 2018

A first-in-human phase I trial of LY2780301, a dual p70 S6 kinase and Akt Inhibitor, in patients with advanced or metastatic cancer

scientific article published on 24 April 2015

A multifunctional drug nanocarrier for efficient anticancer therapy

scientific article published on 08 December 2018

Afatinib restrains K-RAS–driven lung tumorigenesis

scientific article published on 01 June 2018

An improved quantitative mass spectrometry analysis of tumor specific mutant proteins at high sensitivity

scientific article published on 01 May 2012

Changes in vinexin expression patterns in the mouse testis induced by developmental exposure to 17beta-estradiol.

scientific article

Clinical validation of prospective liquid biopsy monitoring in patients with wild-type RAS metastatic colorectal cancer treated with FOLFIRI-cetuximab

scientific article

Colorectal cancer classification based on gene expression is not associated with FOLFIRI response

Developmental regulation of expression of Ran/M1 and Ran/M2 isoforms of Ran-GTPase in mouse testis.

scientific article published in May 2003

Discovery of new targets to control metastasis in pancreatic cancer by single cell transcriptomics analysis of circulating tumor cells

scientific article published on 04 June 2020

Expression of stress inducible protein 1 (Stip1) in the mouse testis

scientific article published in November 2006

Gene silencing by RNAi in mouse Sertoli cells

scientific article

Genetic aberrations in DNA repair pathways: a cornerstone of precision oncology in prostate cancer

scientific article published on 27 October 2020

Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring MET Exon 14 Mutations and Overcomes Mutation-Mediated Resistance to Type I MET Inhibitors in Nonclinical Models.

scientific article

Immunotherapeutic effects of intratumoral nanoplexed poly I:C

scientific article published on 02 May 2019

Integrated next-generation sequencing and avatar mouse models for personalized cancer treatment

scientific article

Intratumoral nanoplexed poly I:C BO-112 in combination with systemic anti-PD-1 for patients with anti-PD-1-refractory tumors

scientific article published on 01 October 2020

Lurbinectedin induces depletion of tumor-associated macrophages, an essential component of its in vivo synergism with gemcitabine, in pancreatic adenocarcinoma mouse models.

scientific article published on 20 October 2016

MT1-MMP as a PET Imaging Biomarker for Pancreas Cancer Management

scientific article published on 26 August 2018

Metabolomic evaluation of Mitomycin C and rapamycin in a personalized treatment of pancreatic cancer.

scientific article

Monitoring vascular normalization induced by antiangiogenic treatment with (18)F-fluoromisonidazole-PET.

scientific article published on 22 December 2015

New scaffolds for the design of selective estrogen receptor modulators

scientific article

OMTX705, a Novel FAP-Targeting ADC demonstrates Activity in Chemotherapy and PD1-Resistant Solid Tumors Models

scientific article published on 11 March 2020

PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data.

scientific article

Pancreas Cancer Precision Treatment Using Avatar Mice from a Bioinformatics Perspective

scientific article published in September 2017

Personalized RNA-medicine for pancreatic cancer

scientific article published on 12 January 2018

Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumors

scientific article published in April 2015

Phase II pilot study of the prednisone to dexamethasone switch in metastatic castration-resistant prostate cancer (mCRPC) patients with limited progression on abiraterone plus prednisone (SWITCH study)

scientific article published on 21 August 2018

Phosphoprotein enriched in astrocytes-15 is expressed in mouse testis and protects spermatocytes from apoptosis.

scientific article published on April 2007

Prioritizing Phase I Treatment Options Through Preclinical Testing on Personalized Tumorgraft

scientific article published on December 19, 2011

Ran GTPase expression during early development of the mouse embryo.

scientific article published in April 2002

Regulation of flotillin-1 in the establishment of NIH-3T3 cell-cell interactions.

scientific article published on December 2003

Reply: 'Comments on Stromal disrupting effects of nab-paclitaxel in pancreatic cancer'.

scientific article published on 18 March 2014

SPARC Expression Did Not Predict Efficacy of nab-Paclitaxel plus Gemcitabine or Gemcitabine Alone for Metastatic Pancreatic Cancer in an Exploratory Analysis of the Phase III MPACT Trial

scientific article published on 13 July 2015

SPARC-Independent Delivery of Nab-Paclitaxel without Depleting Tumor Stroma in Patient-Derived Pancreatic Cancer Xenografts

scientific article published on February 2016

Stromal disrupting effects of nab-paclitaxel in pancreatic cancer

scientific article

The effects of different endocrine disruptors defining compound-specific alterations of gene expression profiles in the developing testis.

scientific article published on 5 January 2012

The expression patterns of genes involved in the RNAi pathways are tissue-dependent and differ in the germ and somatic cells of mouse testis.

scientific article published on 14 February 2008

Transcriptional dissection of pancreatic tumors engrafted in mice.

scientific article

Uncoupling interferon signaling and antigen presentation to overcome immunotherapy resistance due to JAK1 loss in melanoma

scientific article published on 01 October 2020

Whole Exome Sequencing of Rapid Autopsy Tumors and Xenograft Models Reveals Possible Driver Mutations Underlying Tumor Progression

scientific article published on 10 November 2015

c-RAF Ablation Induces Regression of Advanced Kras/Trp53 Mutant Lung Adenocarcinomas by a Mechanism Independent of MAPK Signaling.

scientific article