Search filters

List of works by Giovanni Gadda

A Reversible, Charge-Induced Intramolecular C4a-S-Cysteinyl-Flavin in Choline Oxidase Variant S101C.

scientific article

A novel activity for fungal nitronate monooxygenase: detoxification of the metabolic inhibitor propionate-3-nitronate

scientific article published on 21 March 2012

A pH switch affects the steady-state kinetic mechanism of pyranose 2-oxidase from Trametes ochracea.

scientific article published on 30 December 2008

Alcohol oxidation by flavoenzymes

scientific article

Amine oxidation by d-arginine dehydrogenase in Pseudomonas aeruginosa

scientific article published on 15 June 2017

An internal equilibrium preorganizes the enzyme-substrate complex for hydride tunneling in choline oxidase.

scientific article

Atomic-resolution structure of an N5 flavin adduct in D-arginine dehydrogenase

scientific article

Biochemical and physical characterization of the active FAD-containing form of nitroalkane oxidase from Fusarium oxysporum.

scientific article published on April 1998

Characterization of 2-oxo-3-pentynoate as an active-site-directed inactivator of flavoprotein oxidases: identification of active-site peptides in tryptophan 2-monooxygenase

scientific article published on 01 May 1999

Cloning of nitroalkane oxidase from Fusarium oxysporum identifies a new member of the acyl-CoA dehydrogenase superfamily.

scientific article

Cofactor assisted enzymatic catalysis

scientific article published on 01 February 2014

Conformational changes and substrate recognition in Pseudomonas aeruginosa D-arginine dehydrogenase

scientific article

Conserved Hydration Sites in Pin1 Reveal a Distinctive Water Recognition Motif in Proteins.

scientific article published on 11 December 2015

Contribution of flavin covalent linkage with histidine 99 to the reaction catalyzed by choline oxidase.

scientific article published on 27 April 2009

Crystal structure of yeast nitronate monooxygenase from Cyberlindnera saturnus.

scientific article published on 31 January 2018

Design and application of a class of sensors to monitor Ca2+ dynamics in high Ca2+ concentration cellular compartments

scientific article

Designing protease sensors for real-time imaging of trypsin activation in pancreatic cancer cells.

scientific article published on April 2009

Effect of a conservative mutation of an active site residue involved in substrate binding on the hydride tunneling reaction catalyzed by choline oxidase.

scientific article published on 3 August 2009

Effect of salt and pH on the reductive half-reaction of Mycobacterium tuberculosis FprA with NADPH.

scientific article

Effects of reversing the protein positive charge in the proximity of the flavin N(1) locus of choline oxidase.

scientific article published in March 2006

Enzyme-Mediated Conversion of Flavin Adenine Dinucleotide (FAD) to 8-Formyl FAD in Formate Oxidase Results in a Modified Cofactor with Enhanced Catalytic Properties.

scientific article published on 22 June 2017

Evidence for proton tunneling and a transient covalent flavin-substrate adduct in choline oxidase S101A.

scientific article published on 23 August 2017

Fluorescence Properties of Flavin Semiquinone Radicals in Nitronate Monooxygenase

scientific article published on 20 May 2019

Functional Annotation of a Presumed Nitronate Monoxygenase Reveals a New Class of NADH:Quinone Reductases

scientific journal article

Guest editor's introduction. Special issue on oxidative enzymes

scientific article published on 01 January 2010

Human choline dehydrogenase: medical promises and biochemical challenges.

scientific article published on 29 July 2013

Hydride transfer made easy in the reaction of alcohol oxidation catalyzed by flavin-dependent oxidases.

scientific article published on December 2008

Identification of a cysteine residue in the active site of nitroalkane oxidase by modification with N-ethylmaleimide.

scientific article

Identification of the catalytic base for alcohol activation in choline oxidase

scientific article published on 18 December 2014

Importance of Loop L1 Dynamics for Substrate Capture and Catalysis in Pseudomonas aeruginosa d-Arginine Dehydrogenase.

scientific article published on 26 April 2017

Importance of a serine proximal to the C(4a) and N(5) flavin atoms for hydride transfer in choline oxidase

scientific article published on 11 January 2011

Importance of glutamate 87 and the substrate α-amine for the reaction catalyzed by D-arginine dehydrogenase

scientific article published on 28 January 2015

Inflated kinetic isotope effects in the branched mechanism of Neurospora crassa 2-nitropropane dioxygenase.

scientific article published in March 2009

Insights on the mechanism of amine oxidation catalyzed by D-arginine dehydrogenase through pH and kinetic isotope effects.

scientific article published on 31 October 2011

Kinetic Characterization of PA1225 from Pseudomonas aeruginosa PAO1 Reveals a New NADPH:Quinone Reductase

scientific article published on 11 May 2018

Kinetic Investigation of a Presumed Nitronate Monooxygenase from Pseudomonas aeruginosa PAO1 Establishes a New Class of NAD(P)H:Quinone Reductases

scientific article published on 22 May 2019

Kinetic Solvent Viscosity Effects as Probes for Studying the Mechanisms of Enzyme Action

scientific article published on 13 June 2018

Kinetic and Bioinformatic Characterization of d-2-Hydroxyglutarate Dehydrogenase from <i>Pseudomonas aeruginosa</i> PAO1

scientific article published on 10 December 2020

Kinetic solvent viscosity effects uncover an internal isomerization of the enzyme-substrate complex in Pseudomonas aeruginosa PAO1 NADH:Quinone oxidoreductase

scientific article published in 2022

Kinetics of heme transfer by the Shr NEAT domains of Group A Streptococcus.

scientific article

Mala s 12 is a major allergen in patients with atopic eczema and has sequence similarities to the GMC oxidoreductase family.

scientific article published on 20 February 2007

Mechanistic and computational studies of the reductive half-reaction of tyrosine to phenylalanine active site variants of D-arginine dehydrogenase

scientific article published on 7 October 2014

Mechanistic studies of choline oxidase with betaine aldehyde and its isosteric analogue 3,3-dimethylbutyraldehyde.

scientific article

Mechanistic studies of formate oxidase from Aspergillus oryzae: A novel member of the glucose-Methanol-choline oxidoreductase enzyme superfamily that oxidizes carbon acids.

scientific article published on 16 February 2018

On the catalytic mechanism of choline oxidase

scientific article (publication date: 23 February 2005)

On the contribution of the positively charged headgroup of choline to substrate binding and catalysis in the reaction catalyzed by choline oxidase

scientific article published on 03 May 2006

Photoirradiation Generates an Ultrastable 8-Formyl FAD Semiquinone Radical with Unusual Properties in Formate Oxidase

scientific article published on 27 September 2018

Probing the chemical steps of nitroalkane oxidation catalyzed by 2-nitropropane dioxygenase with solvent viscosity, pH, and substrate kinetic isotope effects.

scientific article published in November 2006

Relative timing of hydrogen and proton transfers in the reaction of flavin oxidation catalyzed by choline oxidase.

scientific article published on 4 February 2013

Rescuing of the hydride transfer reaction in the Glu312Asp variant of choline oxidase by a substrate analogue.

scientific article published on 4 May 2010

Role of F357 as an Oxygen Gate in the Oxidative Half-Reaction of Choline Oxidase

scientific article published on 03 March 2016

Same Substrate, Many Reactions: Oxygen Activation in Flavoenzymes

scientific article

Spectroscopic and kinetic properties of recombinant choline oxidase from Arthrobacter globiformis.

scientific article published in December 2003

Stabilization of an intermediate in the oxidative half-reaction of human liver glycolate oxidase.

scientific article

Steady-state kinetic mechanism and reductive half-reaction of D-arginine dehydrogenase from Pseudomonas aeruginosa.

scientific article published on November 2010

Stepwise Hydrogen Atom and Proton Transfers in Dioxygen Reduction by Aryl-Alcohol Oxidase.

scientific article published on 27 February 2018

Steric hindrance controls pyridine nucleotide specificity of a flavin-dependent NADH:quinone oxidoreductase

scientific article published on 31 October 2018

Structural and kinetic studies on the Ser101Ala variant of choline oxidase: catalysis by compromise

scientific article

Structural determinants for substrate specificity of flavoenzymes oxidizing d-amino acids

scientific article published on 10 October 2018

Structure of choline oxidase in complex with the reaction product glycine betaine

scientific article

Substitution of an active site valine uncovers a kinetically slow equilibrium between competent and incompetent forms of choline oxidase.

scientific article

Substitutions of S101 decrease proton and hydride transfers in the oxidation of betaine aldehyde by choline oxidase

scientific article published on 10 October 2017

Substrate specificity of a nitroalkane-oxidizing enzyme

scientific article published on 01 March 1999

The COMBREX project: design, methodology, and initial results

scientific article

The Combined Structural and Kinetic Characterization of a Bacterial Nitronate Monooxygenase from Pseudomonas aeruginosa PAO1 Establishes NMO Class I and II

scientific article

The chemistry of escapin: identification and quantification of the components in the complex mixture generated by an L-amino acid oxidase in the defensive secretion of the sea snail Aplysia californica

scientific article

The cluster of hydrophobic residues controls the entrance to the active site of choline oxidase.

scientific article published in October 2009

The nonoxidative conversion of nitroethane to ethylnitronate in Neurospora crassa 2-nitropropane dioxygenase is catalyzed by histidine 196.

scientific article published on 9 August 2008

The trimethylammonium headgroup of choline is a major determinant for substrate binding and specificity in choline oxidase

scientific article

Trapping choline oxidase in a nonfunctional conformation by freezing at low pH

scientific article published on 01 February 2007

Paulina is supported by:

About Paulina

Help