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List of works by Alejandro P. Comellas

Ambient particulate matter affects occludin distribution and increases alveolar transepithelial electrical conductance

scientific article

An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup

article

Association of Long-term Ambient Ozone Exposure With Respiratory Morbidity in Smokers

scientific article published on 09 December 2019

Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort

scientific article published on 13 February 2020

Beta-adrenergic agonists regulate Na-K-ATPase via p70S6k.

scientific article published on 18 April 2003

CFTR is required for maximal transepithelial liquid transport in pig alveolar epithelia

scientific article

COPDGene® 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease

scientific article published on 01 November 2019

Characterizing Subjects Exposed to Humidifier Disinfectants Using Computed-Tomography-Based Latent Traits: A Deep Learning Approach

scientific article published in 2022

Clinical and computed tomographic predictors of chronic bronchitis in COPD: a cross sectional analysis of the COPDGene study

scientific article

Clinical phenotypes of atopy and asthma in COPD: a meta-analysis of SPIROMICS and COPDGene

scientific article published on 22 May 2020

Combined Forced Expiratory Volume in 1 Second and Forced Vital Capacity Bronchodilator Response, Exacerbations, and Mortality in Chronic Obstructive Pulmonary Disease

scientific article published on 01 July 2019

Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.

scientific article

Comparison between an alternative and the classic definition of chronic bronchitis in COPDGene

scientific article published on March 2015

Contribution of Individual and Neighborhood Factors to Racial Disparities in Respiratory Outcomes

scientific article published on 02 October 2020

Cortisol levels and mortality in severe sepsis.

scientific article published in January 2004

Defining Chronic Mucus Hypersecretion Using the CAT in the SPIROMICS Cohort

scientific article published on 13 October 2020

Design of the Subpopulations and Intermediate Outcome Measures in COPD (SPIROMICS) AIR Study

scientific article published on 18 May 2017

Differentiation of quantitative CT imaging phenotypes in asthma versus COPD.

scientific article published on 9 November 2017

Disproportionate contribution of right middle lobe to emphysema and gas trapping on computed tomography

scientific article

Dopamine increases lung liquid clearance during mechanical ventilation.

scientific article

Dopamine restores lung ability to clear edema in rats exposed to hyperoxia

scientific article published in February 1999

Effect of Fenoterol on PAF-induced lung edema in isolated and perfused rabbit lungs

scientific article published on 01 November 1998

Effect of hydrocortisone on platelet activating factor induced lung edema in isolated rabbit lungs

scientific article published on 01 March 2000

Effect of platelet activating factor (PAF) on pulmonary circulation in isolated rabbit lung

scientific article published on 01 March 1999

Effects of Eyjafjallajökull volcanic ash on innate immune system responses and bacterial growth in vitro

scientific article published on 11 March 2013

Electrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense

scientific article published on 22 January 2016

Epidermal growth factor receptor and claudin-2 participate in A549 permeability and remodeling: implications for non-small cell lung cancer tumor colonization

scientific article published on June 2009

Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort

scientific article

Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease

scientific article

Hypoxia increases transepithelial electrical conductance and reduces occludin at the plasma membrane in alveolar epithelial cells via PKC-ζ and PP2A pathway.

scientific article

Hypoxia-mediated degradation of Na,K-ATPase via mitochondrial reactive oxygen species and the ubiquitin-conjugating system

scientific article published on 13 April 2006

Imaging-based clusters in current smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)

scientific article published on 18 September 2018

Imaging-based clusters in former smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and intermediate outcome measures in COPD study (SPIROMICS)

scientific article published on 15 July 2019

Increased airway iron parameters and risk for exacerbation in COPD: an analysis from SPIROMICS

scientific article published on 29 June 2020

Iron oxide nanoparticles induce Pseudomonas aeruginosa growth, induce biofilm formation, and inhibit antimicrobial peptide function

scientific article

Isoproterenol improves ability of lung to clear edema in rats exposed to hyperoxia

scientific article published in July 1999

Lower serum IgA is associated with COPD exacerbation risk in SPIROMICS.

scientific article published on 12 April 2018

Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers

scientific article published on 12 November 2020

Occupational Exposures Influence CT Imaging Characteristics in the SPIROMICS Cohort

scientific article published on 01 December 2018

Persistent and Newly Developed Chronic Bronchitis Are Associated with Worse Outcomes in Chronic Obstructive Pulmonary Disease

scientific article published on 09 May 2016

Post–COVID-19 Vocal Cord Dysfunction

scientific article published in 2022

Prediction of acute respiratory disease in current and former smokers with and without COPD

scientific article

Protein Kinase C–ζ Mediates Lung Injury Induced by Diesel Exhaust Particles ⬇️

scientific article published on December 6, 2012

Radiographic lung volumes predict progression to COPD in smokers with preserved spirometry in SPIROMICS

scientific article published on 31 October 2019

Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort

scientific article published on May 2017

Reversible Airflow Obstruction Predicts Future Chronic Obstructive Pulmonary Disease Development in the SPIROMICS Cohort: An Observational Cohort Study

scientific article published in 2022

Role of PON in anoxia-reoxygenation injury: a Drosophila melanogaster transgenic model

scientific article published on 06 January 2014

Role of endothelin-1 in acute lung injury.

scientific article

Rural Residence and COPD Exacerbations: Analysis of the SPIROMICS Cohort

scientific article published on 27 March 2018

Satellite-based PM concentrations and their application to COPD in Cleveland, OH

scientific article published on 18 September 2013

Scorpion venom decreases lung liquid clearance in rats.

scientific article published on 24 January 2003

Serum amino acid concentrations and clinical outcomes in smokers: SPIROMICS metabolomics study

scientific article published on 06 August 2019

Systemic Markers of Inflammation in Smokers With Symptoms Despite Preserved Spirometry in SPIROMICS

scientific article published on 23 January 2019

The Association Between Neighborhood Socioeconomic Disadvantage and Chronic Obstructive Pulmonary Disease

scientific article published on 05 May 2020

The Association Between Technology Use and Health Status in a Chronic Obstructive Pulmonary Disease Cohort: Multi-Method Study.

scientific article published on 2 April 2018

The association of plasma biomarkers with computed tomography-assessed emphysema phenotypes

scientific article

Time course of active and passive liquid and solute movement in the isolated perfused rat lung model

scientific article published in October 1998

Ventilator-associated lung injury decreases lung ability to clear edema and downregulates alveolar epithelial cell Na,K-adenosine triphosphatase function

scientific article published on 01 July 1999

Ventilator-associated lung injury decreases lung ability to clear edema in rats

scientific article published on 01 February 1999

[Comparison of the sensitivity and specificity of the electrocardiography criteria for left ventricular hypertrophy according to the methods of Romhilt-Estes, Sokolow-Lyon, Cornell and Rodríguez Padial]

scientific article published on 01 January 1997

beta-adrenergic stimulation restores rat lung ability to clear edema in ventilator-associated lung injury.

scientific article published in July 2000

beta-agonists regulate Na,K-ATPase via novel MAPK/ERK and rapamycin-sensitive pathways

scientific article published on 01 December 2000

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