List of works - Sanjiv A Luther

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

scientific article published on September 2017

ADAMTS18+ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels

scientific article published in 2022

Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts

scientific article published on 15 July 2019

B cell response after MMTV infection: extrafollicular plasmablasts represent the main infected population and can transmit viral infection

article

B cell response and histology of a retroviral infection in vivo

scientific article published on 01 April 1997

BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis.

scientific article published on May 2000

Bimodal Expansion of the Lymphatic Vessels Is Regulated by the Sequential Expression of IL-7 and Lymphotoxin α1β2 in Newly Formed Tertiary Lymphoid Structures

scientific article published on 29 July 2016

CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima

scientific article published on 26 September 2016

CCL21 is sufficient to mediate DC migration, maturation and function in the absence of CCL19

scientific article published on 01 May 2010

CD8 engineered cytotoxic T cells reprogram melanoma tumor environment.

scientific article published on 11 September 2015

Chemokines as regulators of T cell differentiation.

scientific article

Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse

scientific article published in November 2000

Conditional deletion of ferritin h in mice reduces B and T lymphocyte populations

scientific article

Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells.

scientific article published in December 2008

DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport

scientific article

Definition of key variables for the induction of optimal NY-ESO-1-specific T cells in HLA transgene mice.

scientific article published on 23 August 2010

Destruction of lymphoid organ architecture and hepatitis caused by CD4+ T cells.

scientific article

Detection of a sulfotransferase (HEC-GlcNAc6ST) in high endothelial venules of lymph nodes and in high endothelial venule-like vessels within ectopic lymphoid aggregates: relationship to the MECA-79 epitope.

scientific article

Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis.

scientific article published in July 2002

Dynamic modulation of CCR7 expression and function on naive T lymphocytes in vivo

scientific article published on 01 December 2008

Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies

scientific article published on 13 November 2009

Early neutralizing antibody response against mouse mammary tumor virus: critical role of viral infection and superantigen-reactive T cells.

scientific article published in September 1997

Erratum: CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima.

scientific article published on May 2017

Essential role of CCL21 in establishment of central self-tolerance in T cells.

scientific article published on 13 June 2017

Expression and function of interleukin-7 in secondary and tertiary lymphoid organs.

scientific article published on 22 March 2012

FOXC2 controls adult lymphatic endothelial specialization, function, and gut lymphatic barrier preventing multiorgan failure

scientific article published in 2021

Fibroblast-derived IL-33 is dispensable for lymph node homeostasis but critical for CD8 T cell responses to acute and chronic viral infection

scientific article published on 22 July 2020

Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands

scientific article published on 20 March 2017

Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide

scientific article

Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells.

scientific article published on 23 September 2007

Follicular stromal cells and lymphocyte homing to follicles.

scientific article

Formation of the Intrathymic Dendritic Cell Pool Requires CCL21-Mediated Recruitment of CCR7+ Progenitors to the Thymus.

scientific article published on 21 May 2018

Guiding blind T cells and dendritic cells: A closer look at fibroblastic reticular cells found within lymph node T zones ⬇️

scientific article published on February 17, 2011

IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs

scientific article

IL-4Rα-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells

scientific article published on 01 May 2019

Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis.

scientific article published on 2 July 2018

Immune response to mouse mammary tumour virus.

scientific article published on August 1996

Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology

scientific article published on 18 June 2019

Inducible gene expression in fetal thymic epithelium: a new BAC transgenic model.

scientific article published on 7 August 2013

Innate signaling promotes formation of regulatory nitric oxide-producing dendritic cells limiting T-cell expansion in experimental autoimmune myocarditis

scientific article published on 13 May 2013

Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis

scientific article

Interplays between mouse mammary tumor virus and the cellular and humoral immune response.

scientific article

Interstitial dendritic cell guidance by haptotactic chemokine gradients

scientific article

Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy

scientific article published on 08 January 2019

Lack of Adipocytes Alters Hematopoiesis in Lipodystrophic Mice

scientific article published on 13 November 2018

Lymphotoxin-Dependent B Cell-FRC Crosstalk Promotes De Novo Follicle Formation and Antibody Production following Intestinal Helminth Infection.

scientific article published on 4 May 2016

Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity.

scientific article

Manifold Roles of CCR7 and Its Ligands in the Induction and Maintenance of Bronchus-Associated Lymphoid Tissue.

scientific article

Mouse mammary tumor virus: immunological interplays between virus and host

scientific article published on January 1, 1997

Multiple roles of lymphatic vessels in peripheral lymph node development

article

New infectious mammary tumor virus superantigen with V beta-specificity identical to staphylococcal enterotoxin B (SEB).

scientific article published on August 1994

Notch Signaling Regulates the Homeostasis of Tissue-Restricted Innate-like T Cells.

scientific article published on 20 June 2016

Notch signaling regulates follicular helper T cell differentiation

scientific article published on 5 August 2013

Novel function for interleukin-7 in dendritic cell development

scientific article published on 25 February 2009

Overlapping roles of CXCL13, interleukin 7 receptor alpha, and CCR7 ligands in lymph node development

scientific journal article

Perivascular Fibroblasts of the Developing Spleen Act as LTα1β2-Dependent Precursors of Both T and B Zone Organizer Cells

scientific article published in November 2017

Plasma cell precursors: long-distance travelers looking for a home

scientific article published on 01 July 2010

Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes.

scientific article

Preferential infection of immature dendritic cells and B cells by mouse mammary tumor virus.

scientific article published in April 2002

Recirculating CD4 memory T cells mount rapid secondary responses without major contributions from follicular CD4 effectors and B cells

scientific article published in June 2007

Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy.

scientific article

Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone

scientific article published on 20 April 2008

Single-Cell RNA Sequencing of Lymph Node Stromal Cells Reveals Niche-Associated Heterogeneity

scientific article published on 08 May 2018

Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses

scientific article

Stromal Fibroblasts in Tertiary Lymphoid Structures: A Novel Target in Chronic Inflammation

scientific article

T Helper 1 (Th1) and Th2 Characteristics Start to Develop During T Cell Priming and Are Associated with an Immediate Ability to Induce Immunoglobulin Class Switching ⬇️

scientific article published on April 20, 1998

TLR2 Signaling in Skin Nonhematopoietic Cells Induces Early Neutrophil Recruitment in Response to Leishmania major Infection

scientific article published on 27 December 2018

The aged lymphoid tissue environment fails to support naïve T cell homeostasis

scientific article published on 02 August 2016

The role of neutralizing antibodies for mouse mammary tumor virus transmission and mammary cancer development.

scholarly article

Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease

scientific article published on 16 January 2005

Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes

scientific article published on 23 December 2013

Treatment of ongoing autoimmune encephalomyelitis with activated B-cell progenitors maturing into regulatory B cells

scientific article published on 11 July 2016

List of works by Sanjiv A Luther

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

ADAMTS18+ villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels

Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts

B cell response after MMTV infection: extrafollicular plasmablasts represent the main infected population and can transmit viral infection

B cell response and histology of a retroviral infection in vivo

BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis.

Bimodal Expansion of the Lymphatic Vessels Is Regulated by the Sequential Expression of IL-7 and Lymphotoxin α1β2 in Newly Formed Tertiary Lymphoid Structures

CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima

CCL21 is sufficient to mediate DC migration, maturation and function in the absence of CCL19

CD8 engineered cytotoxic T cells reprogram melanoma tumor environment.

Chemokines as regulators of T cell differentiation.

Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse

Conditional deletion of ferritin h in mice reduces B and T lymphocyte populations

Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells.

DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport

Definition of key variables for the induction of optimal NY-ESO-1-specific T cells in HLA transgene mice.

Destruction of lymphoid organ architecture and hepatitis caused by CD4+ T cells.

Detection of a sulfotransferase (HEC-GlcNAc6ST) in high endothelial venules of lymph nodes and in high endothelial venule-like vessels within ectopic lymphoid aggregates: relationship to the MECA-79 epitope.

Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis.

Dynamic modulation of CCR7 expression and function on naive T lymphocytes in vivo

Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies

Early neutralizing antibody response against mouse mammary tumor virus: critical role of viral infection and superantigen-reactive T cells.

Erratum: CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima.

Essential role of CCL21 in establishment of central self-tolerance in T cells.

Expression and function of interleukin-7 in secondary and tertiary lymphoid organs.

FOXC2 controls adult lymphatic endothelial specialization, function, and gut lymphatic barrier preventing multiorgan failure

Fibroblast-derived IL-33 is dispensable for lymph node homeostasis but critical for CD8 T cell responses to acute and chronic viral infection

Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands

Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide

Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells.

Follicular stromal cells and lymphocyte homing to follicles.

Formation of the Intrathymic Dendritic Cell Pool Requires CCL21-Mediated Recruitment of CCR7+ Progenitors to the Thymus.

Guiding blind T cells and dendritic cells: A closer look at fibroblastic reticular cells found within lymph node T zones ⬇️

IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs

IL-4Rα-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells

Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis.

Immune response to mouse mammary tumour virus.

Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology

Inducible gene expression in fetal thymic epithelium: a new BAC transgenic model.

Innate signaling promotes formation of regulatory nitric oxide-producing dendritic cells limiting T-cell expansion in experimental autoimmune myocarditis

Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis

Interplays between mouse mammary tumor virus and the cellular and humoral immune response.

Interstitial dendritic cell guidance by haptotactic chemokine gradients

Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy

Lack of Adipocytes Alters Hematopoiesis in Lipodystrophic Mice

Lymphotoxin-Dependent B Cell-FRC Crosstalk Promotes De Novo Follicle Formation and Antibody Production following Intestinal Helminth Infection.

Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity.

Manifold Roles of CCR7 and Its Ligands in the Induction and Maintenance of Bronchus-Associated Lymphoid Tissue.

Mouse mammary tumor virus: immunological interplays between virus and host

Multiple roles of lymphatic vessels in peripheral lymph node development

New infectious mammary tumor virus superantigen with V beta-specificity identical to staphylococcal enterotoxin B (SEB).

Notch Signaling Regulates the Homeostasis of Tissue-Restricted Innate-like T Cells.

Notch signaling regulates follicular helper T cell differentiation

Novel function for interleukin-7 in dendritic cell development

Overlapping roles of CXCL13, interleukin 7 receptor alpha, and CCR7 ligands in lymph node development

Perivascular Fibroblasts of the Developing Spleen Act as LTα1β2-Dependent Precursors of Both T and B Zone Organizer Cells

Plasma cell precursors: long-distance travelers looking for a home

Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes.

Preferential infection of immature dendritic cells and B cells by mouse mammary tumor virus.

Recirculating CD4 memory T cells mount rapid secondary responses without major contributions from follicular CD4 effectors and B cells

Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy.

Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone

Single-Cell RNA Sequencing of Lymph Node Stromal Cells Reveals Niche-Associated Heterogeneity

Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses

Stromal Fibroblasts in Tertiary Lymphoid Structures: A Novel Target in Chronic Inflammation

T Helper 1 (Th1) and Th2 Characteristics Start to Develop During T Cell Priming and Are Associated with an Immediate Ability to Induce Immunoglobulin Class Switching ⬇️

TLR2 Signaling in Skin Nonhematopoietic Cells Induces Early Neutrophil Recruitment in Response to Leishmania major Infection

The aged lymphoid tissue environment fails to support naïve T cell homeostasis

The role of neutralizing antibodies for mouse mammary tumor virus transmission and mammary cancer development.

Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease

Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes

Treatment of ongoing autoimmune encephalomyelitis with activated B-cell progenitors maturing into regulatory B cells