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List of works by David H. Raulet

A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated repression.

scientific article

A differentiation factor required for the expression of cytotoxic T-cell function

scientific article published in Nature

A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells

scientific article

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity

scientific journal article

A selective role of NKG2D in inflammatory and autoimmune diseases

scientific article published on 14 September 2013

A sense of something missing

scientific article published in Nature

A simple and effective method for differentiating GFP and YFP by flow cytometry using the violet laser

scientific article

A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules

scientific article published on 22 February 2005

ATM-dependent spontaneous regression of early Eμ-myc-induced murine B-cell leukemia depends on natural killer and T cells

scientific article

Acquisition of Ly49 Receptor Expression by Developing Natural Killer Cells ⬇️

scientific article published on February 16, 1998

Activation and self-tolerance of natural killer cells

scientific article published on December 2006

Allelic exclusion of Ly49-family genes encoding class I MHC-specific receptors on NK cells.

scientific article

Amelioration of acute graft-versus-host disease by NKG2A engagement on donor T cells

scientific article published on 01 August 2005

An RNA-Based Fluorescent Biosensor for High-Throughput Analysis of the cGAS-cGAMP-STING Pathway

scientific article

Antitumor immunity. A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection

scientific article published on 5 March 2015

Author Correction: SLC19A1 transports immunoreactive cyclic dinucleotides

scientific article published on 01 March 2020

Bacterial Manipulation of NK Cell Regulatory Activity Increases Susceptibility to Listeria monocytogenes Infection.

scientific article

Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells. 1990.

scientific article published in May 2010

Binding of diverse peptides to MHC class I molecules inhibits target cell lysis by activated natural killer cells

scientific article published on January 1995

Blastocyst MHC, a putative murine homologue of HLA-G, protects TAP-deficient tumor cells from natural killer cell-mediated rejection in vivo

scientific journal article

Bone Marrow Cell Rejection, MHC, NK Cells, and Missing Self Recognition: Ain't That Peculiar (with Apologies to Marvin Gaye).

scientific article published on October 2015

Characterization of a novel NKG2D and NKp46 double-mutant mouse reveals subtle variations in the NK cell repertoire

scientific article published on 06 May 2013

Chemotherapy-induced genotoxic stress promotes sensitivity to natural killer cell cytotoxicity by enabling missing-self recognition

scientific article

Clonal acquisition of inhibitory Ly49 receptors on developing NK cells is successively restricted and regulated by stromal class I MHC.

scientific article published on July 2000

Cloning of a mouse homolog of CD94 extends the family of C‐type lectins on murine natural killer cells ⬇️

scientific article published on December 1, 1997

Comparative analysis of human NK cell activation induced by NKG2D and natural cytotoxicity receptors

scientific article

Contrasting roles of DAP10 and KARAP/DAP12 signaling adaptors in activation of the RBL-2H3 leukemic mast cell line

scientific article published on December 2003

Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade.

scientific article published on 10 September 2018

Control of gamma delta T-cell development.

scientific article

Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease

scientific article published in September 2004

Costimulation of dendritic epidermal gammadelta T cells by a new NKG2D ligand expressed specifically in the skin

scientific article

Cutting edge: tumor rejection mediated by NKG2D receptor-ligand interaction is dependent upon perforin

scientific article published in November 2002

Cytokine therapy restores antitumor responses of NK cells rendered anergic in MHC I-deficient tumors

scientific article published on 05 June 2015

Cytokine therapy reverses NK cell anergy in MHC-deficient tumors

scientific article

Cytokine treatment in cancer immunotherapy

scientific article published on August 2015

DNA mismanagement leads to immune system oversight

scientific article published on November 2007

Development and selection of gammadelta T cells

scientific article published on February 2007

Development and tolerance of natural killer cells.

scientific article

Developmental potential and dynamic behavior of hematopoietic stem cells

scientific article published in June 1986

Developmental regulation of T-cell receptor gene expression

scientific article published in Nature

Differential Role of Hematopoietic and Nonhematopoietic Cell Types in the Regulation of NK Cell Tolerance and Responsiveness

scientific article published on 19 October 2016

Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors.

scientific article published on July 1999

Diversity, rearrangement, and expression of murine T cell gamma genes

scientific article

Does a Low Level of Expression of HLA Molecules Engender Autoimmunity?

scientific article published on 01 January 1999

Dysregulated cellular functions and cell stress pathways provide critical cues for activating and targeting natural killer cells to transformed and infected cells

scientific article published in November 2017

Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells

scientific article

Endothelial cells express NKG2D ligands and desensitize anti-tumor NK responses.

scientific article published on 12 December 2017

Events that regulate differentiation of alpha beta TCR+ and gamma delta TCR+ T cells from a common precursor.

scientific article published on June 1997

Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes.

scientific article published in April 1993

Evidence for natural killer cell memory

scientific article published on September 2013

Evidence that gammadelta versus alphabeta T cell fate determination is initiated independently of T cell receptor signaling.

scientific article

Evidence that productive rearrangements of TCR gamma genes influence the commitment of progenitor cells to differentiate into alpha beta or gamma delta T cells.

scientific article published on September 1995

Expansion and function of CD8+ T cells expressing Ly49 inhibitory receptors specific for MHC class I molecules

scientific article published in September 2004

Expression and function of NK cell receptors in CD8+ T cells

scientific article

Expression and function of interleukin-2 receptors on immature thymocytes

scientific article published in March 1985

Expression of natural killer receptor alleles at different Ly49 loci occurs independently and is regulated by major histocompatibility complex class I molecules.

scientific article

Expression of the Ly49A gene in murine natural killer cell clones is predominantly but not exclusively mono‐allelic ⬇️

scientific article published on November 1, 1997

Expression of the RAE-1 family of stimulatory NK-cell ligands requires activation of the PI3K pathway during viral infection and transformation

scientific article

Functionally conformed free class I heavy chains exist on the surface of beta 2 microglobulin negative cells

scientific article

Gene placement and competition control T cell receptor gamma variable region gene rearrangement

scientific article published on 31 March 2008

Genomic Ly49A transgenes: basis of variegated Ly49A gene expression and identification of a critical regulatory element

scientific article published in January 2004

HLA reduces killer cell Ig-like receptor expression level and frequency in a humanized mouse model

scientific article published on 6 February 2013

IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2.

scientific article published on 3 March 2005

Immune activation resulting from NKG2D/ligand interaction promotes atherosclerosis

scientific article published on 21 November 2011

Immune surveillance of unhealthy cells by natural killer cells

scientific article

Immunobiology of MHC Class I-Deficient Mice

Immunosurveillance and immunotherapy of tumors by innate immune cells

scientific article

Immunosurveillance of senescent cancer cells by natural killer cells

scientific article

Impaired natural killer cell self-education and "missing-self" responses in Ly49-deficient mice

scientific article

Implications of CD94 deficiency and monoallelic NKG2A expression for natural killer cell development and repertoire formation

scientific article

Infection-induced regulation of natural killer cells by macrophages and collagen at the lymph node subcapsular sinus

scientific article

Inhibition of MHC class I is a virulence factor in herpes simplex virus infection of mice

scientific article

Inhibitory effects of class I molecules on murine NK cells: speculations on function, specificity and self-tolerance ⬇️

scientific article published on April 1, 1995

Innate immune recognition by stimulatory immunoreceptors

scientific article

Innate or adaptive immunity? The example of natural killer cells

scientific article (publication date: 7 January 2011)

Interplay of natural killer cells and their receptors with the adaptive immune response

scientific article published in October 2004

Killer cells add fire to fuel immunotherapy

scientific article published on 01 May 2020

Listening to each other: Infectious disease and cancer immunology

scientific article

Ly49A transgenic mice provide evidence for a major histocompatibility complex-dependent education process in natural killer cell development.

scientific article

Lymphocyte development

article

MHC class I-deficient mice

scientific article published on January 1994

MICA-Expressing Monocytes Enhance Natural Killer Cell Fc Receptor-Mediated Antitumor Functions

scientific article published on 19 July 2017

Major histocompatibility complex class I-dependent skewing of the natural killer cell Ly49 receptor repertoire.

scientific article

Major histocompatibility complex genes determine natural killer cell tolerance.

scientific article

Mature natural killer cells reset their responsiveness when exposed to an altered MHC environment

scientific article

Millikelvin-resolved ambient thermography

scientific article published on 09 December 2020

Missing self recognition and self tolerance of natural killer (NK) cells

scientific article published in June 2006

Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors

scientific article

Multiple natural killer cell-activating signals are inhibited by major histocompatibility complex class I expression in target cells.

scientific article published in June 1994

Multiplicity and plasticity of natural killer cell signaling pathways

scientific article published on 15 November 2005

Murine cytomegalovirus interference with antigen presentation has little effect on the size or the effector memory phenotype of the CD8 T cell response

scientific article published on June 2004

NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model

scientific article published on April 2009

NK cell self tolerance, responsiveness and missing self recognition

scientific article published on 12 March 2014

NK cells developing in vitro from fetal mouse progenitors express at least one member of the Ly49 family that is acquired in a time-dependent and stochastic manner independently of CD94 and NKG2.

scientific article published in March 2002

NK cells mediate clearance of CD8+ T cell-resistant tumors in response to STING agonists

scientific article published on 01 March 2020

NK cells respond to pulmonary infection with Mycobacterium tuberculosis, but play a minimal role in protection

scientific article published in December 2003

NK1.1+ T cells in the liver arise in the thymus and are selected by interactions with class I molecules on CD4+CD8+ cells.

scientific article published on March 2000

NKG2A inhibits invariant NKT cell activation in hepatic injury

scientific article

NKG2D expression by CD8+ T cells contributes to GVHD and GVT effects in a murine model of allogeneic HSCT

scientific article published on 18 March 2015

NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease

scientific article published on 30 March 2012

NKG2D-Deficient Mice Are Defective in Tumor Surveillance in Models of Spontaneous Malignancy

scholarly article by Nadia Guerra et al published May 2008 in Immunity

NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy

scientific article

Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases

scientific journal article

Natural killer cell receptors: the offs and ons of NK cell recognition.

scientific article

Natural killer cells: remembrances of things past

scientific article published on April 2009

Natural-Killer-like B Cells Display the Phenotypic and Functional Characteristics of Conventional B Cells

scientific article

Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells

scientific article published on 12 April 2016

Oncogenic stress sensed by the immune system: role of natural killer cell receptors

scientific article

Ordered rearrangement of variable region genes of the T cell receptor gamma locus correlates with transcription of the unrearranged genes.

scientific article

Orderly and nonstochastic acquisition of CD94/NKG2 receptors by developing NK cells derived from embryonic stem cells in vitro

scientific article published in May 2002

Positive selection of V beta 8+ CD4-8- thymocytes by class I molecules expressed by hematopoietic cells

scientific article

Positive selection of dendritic epidermal gammadelta T cell precursors in the fetal thymus determines expression of skin-homing receptors

scientific journal article

Posttranslational regulation of the NKG2D ligand Mult1 in response to cell stress

scientific article published on 26 January 2009

RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry

scientific article

RAE1 ligands for the NKG2D receptor are regulated by STING-dependent DNA sensor pathways in lymphoma

scientific article

Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity

scientific article published on September 2001

Recognition events that inhibit and activate natural killer cells

scientific article published on June 1996

Recognition of tumors by the innate immune system and natural killer cells

scientific article

Recombination signal sequence-associated restriction on TCRdelta gene rearrangement affects the development of tissue-specific gammadelta T cells

scientific article

Redundant and unique roles of two enhancer elements in the TCRgamma locus in gene regulation and gammadelta T cell development

scientific article published in March 2002

Regulation of NK cell responsiveness to achieve self-tolerance and maximal responses to diseased target cells

scientific article published on August 2008

Regulation of ligands for the NKG2D activating receptor

scientific article

Roles of the NKG2D immunoreceptor and its ligands ⬇️

scientific article published on October 1, 2003

SLC19A1 transports immunoreactive cyclic dinucleotides

scientific article published on 11 September 2019

Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D

scientific article (publication date: December 2002)

Selective expression of Vδ6 genes by B2A2− CD4− CD− T cell receptor γ/δ thymocytes

article

Self-tolerance of natural killer cells

scientific article published on July 2006

Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase

scientific article

Stromal-cell regulation of natural killer cell differentiation

scientific article published on 11 April 2007

T cell gamma receptor

scientific article published on January 1987

T cell receptor gamma gene regulatory sequences prevent the function of a novel TCRgamma/pTalpha pre-T cell receptor

scientific article published in June 1998

T-cell immunity. How gamma delta T cells make a living

scientific article published on March 1994

Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging

scientific article published on 11 June 2019

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor ⬇️

scientific article

The DNA damage response arouses the immune system

scientific article

The DNA damage response, immunity and cancer

scientific article published on 7 July 2006

The MHC reactivity of the T cell repertoire prior to positive and negative selection.

scientific article

The combined actions of NK and T lymphocytes are necessary to reject an EGFP+ mesenchymal tumor through mechanisms dependent on NKG2D and IFN gamma.

scientific article published on September 2007

The developmental fate of T cells is critically influenced by TCRgammadelta expression.

scientific article published in April 1998

The genomic arrangement of T cell receptor variable genes is a determinant of the developmental rearrangement pattern

scholarly article

The innate immune response to tumors and its role in the induction of T-cell immunity

scientific article

The lymphoproliferative defect in CTLA-4-deficient mice is ameliorated by an inhibitory NK cell receptor

The mechanistic study behind suppression of GVHD while retaining GVL activities by myeloid-derived suppressor cells

scientific article published on 08 February 2019

The role of NKG2D signaling in inhibition of cytotoxic T-lymphocyte lysis by the Murine cytomegalovirus immunoevasin m152/gp40

scientific article

The role of innate immunity in autoimmunity.

scientific article published on December 2004

The role of short homology repeats and TdT in generation of the invariant gamma delta antigen receptor repertoire in the fetal thymus.

scientific article published in October 1995

The role of the NKG2D immunoreceptor in immune cell activation and natural killing

scientific article

Tolerance, and more

scientific article published on 01 April 1987

Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response

article

Tumor-derived CSF-1 induces the NKG2D ligand RAE-1δ on tumor-infiltrating macrophages.

scientific article

Turnover and proliferation of NK cells in steady state and lymphopenic conditions

scientific article published in January 2004

Upregulation of CD94/NKG2A receptors and Qa-1b ligand during murine cytomegalovirus infection of salivary glands

scientific article published in May 2007

Viral and bacterial infections induce expression of multiple NK cell receptors in responding CD8(+) T cells

scientific article published in August 2002

Viral infections induce abundant numbers of senescent CD8 T cells

scientific article

p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells

scientific article published on 16 September 2013

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