List of works - Richard J. Servatius

A chronic stress state in rats: effects of repeated stress on basal corticosterone and behavior

scientific article published on 01 April 1992

A comparison of the effects of repeated stressor exposures and corticosterone injections on plasma cholesterol, thyroid hormones and corticosterone levels in rats

scientific article published on 01 January 1994

A model of amygdala-hippocampal-prefrontal interaction in fear conditioning and extinction in animals

scientific article

A stress-induced anxious state in male rats: corticotropin-releasing hormone induces persistent changes in associative learning and startle reactivity.

scientific article published in April 2005

Absence of "Warm-Up" during Active Avoidance Learning in a Rat Model of Anxiety Vulnerability: Insights from Computational Modeling.

scientific article

Acquired equivalence in U.S. veterans with symptoms of posttraumatic stress: reexperiencing symptoms are associated with greater generalization

scientific article

Acquisition and extinction of human avoidance behavior: attenuating effect of safety signals and associations with anxiety vulnerabilities

scientific article

Altered activity of the medial prefrontal cortex and amygdala during acquisition and extinction of an active avoidance task.

scientific article published on 15 September 2015

Avoidance as expectancy in rats: sex and strain differences in acquisition

scientific article

Avoidance perseveration during extinction training in Wistar-Kyoto rats: an interaction of innate vulnerability and stressor intensity.

scientific article published on 2 March 2011

Behavioral inhibition and PTSD symptoms in veterans.

scientific article

Behaviorally inhibited individuals demonstrate significantly enhanced conditioned response acquisition under non-optimal learning conditions.

scientific article published on 23 November 2013

Behaviorally inhibited temperament is associated with severity of post-traumatic stress disorder symptoms and faster eyeblink conditioning in veterans

scientific article

Behaviourally inhibited temperament and female sex, two vulnerability factors for anxiety disorders, facilitate conditioned avoidance (also) in humans.

scientific article published on 09 January 2014

Blocking cholesterol synthesis impairs acquisition of the classically conditioned eyeblink response

scientific article published in April 2000

Brain and Serum Androsterone Is Elevated in Response to Stress in Rats with Mild Traumatic Brain Injury.

scientific article

Brief intermittent light stimulation disrupts saccadic oculomotor control.

scientific article

Cardiovascular evaluation of electronic control device exposure in law enforcement trainees: a multisite study.

scientific article published in February 2010

Cerebellar response to familiar and novel stimuli: An fMRI study.

scientific article published in December 2016

Cholinergic overstimulation supports conditioned-facilitated startle but not conditioned hyperalgesia.

scientific article published on 17 July 2006

Classical and instrumental conditioning of eyeblink responses in Wistar-Kyoto and Sprague-Dawley rats.

scientific article

Cytokine levels during pregnancy influence immunological profiles and neurobehavioral patterns of the offspring.

scientific article published in June 2007

Damage of GABAergic neurons in the medial septum impairs spatial working memory and extinction of active avoidance: effects on proactive interference.

scientific article

Deficient proactive interference of eyeblink conditioning in Wistar-Kyoto rats.

scientific article

Delayed startle sensitization distinguishes rats exposed to one or three stress sessions: further evidence toward an animal model of PTSD

scientific article published on 01 October 1995

Developmental sensitivity of associative learning to cholesterol synthesis inhibitors.

scientific article published in February 2002

Differential effects of progesterone and medroxyprogesterone on delay eyeblink conditioning in ovariectomized rats.

scientific article published on 26 November 2011

Dysfunction in amygdala-prefrontal plasticity and extinction-resistant avoidance: A model for anxiety disorder vulnerability

scientific article published on 4 November 2015

Editorial: Avoidance: From Basic Science to Psychopathology.

scientific article

Effect of life in a constant light environment on the course of hypertension in Dahl rats

scientific article published on 01 June 1993

Effects of inescapable stress and treatment with pyridostigmine bromide on plasma butyrylcholinesterase and the acoustic startle response in rats

scientific article published on 01 May 2000

Effects of psychotropic agents on extinction of lever-press avoidance in a rat model of anxiety vulnerability.

scientific article

Effects of stress on nonassociative learning processes in male and female rats

scientific article published in April 2002

Enhanced avoidance learning in behaviorally inhibited young men and women

scientific article published on 16 January 2013

Enhanced conditioned eyeblink response acquisition and proactive interference in anxiety vulnerable individuals ⬇️

scientific article published on November 16, 2012

Enhanced glutamatergic neurotransmission facilitates classical conditioning in the freely moving rat.

scientific article published in February 1995

Exaggerated acquisition and resistance to extinction of avoidance behavior in treated heroin-dependent men

scientific article published on March 2016

Exposure to morphine-associated cues increases mu opioid receptor mRNA expression in the nucleus accumbens of Wistar Kyoto rats

scientific article published on 12 July 2016

Eyeblink conditioning in the freely moving rat: square-wave stimulation as the unconditioned stimulus

scientific article published in October 2000

Facilitated acquisition of eyeblink conditioning in those vulnerable to anxiety disorders.

scientific article published on 05 July 2013

Facilitated acquisition of standard but not long delay classical eyeblink conditioning in behaviorally inhibited adolescents

scientific article published on 30 October 2014

Facilitated acquisition of the classically conditioned eyeblink response in active duty military expressing posttraumatic stress disorder symptoms

scientific article published on 14 November 2017

Facilitated acquisition of the classically conditioned eyeblink response in females is augmented in those taking oral contraceptives

scientific article published on 17 August 2010

Facilitated acquisition of the classically conditioned eyeblink response in male rats after systemic IL-1beta.

scientific article published on July 2003

Facilitated acquisition of the classically conditioned eyeblink response in women taking oral contraceptives.

scientific article published in December 2008

GABAergic neurons in the medial septum-diagonal band of Broca (MSDB) are important for acquisition of the classically conditioned eyeblink response

scientific article

ITI-Signals and Prelimbic Cortex Facilitate Avoidance Acquisition and Reduce Avoidance Latencies, Respectively, in Male WKY Rats

scientific article

Impaired associative learning in chronic fatigue syndrome ⬇️

scientific article published on April 20, 1998

Increased generalization of learned associations is related to re-experiencing symptoms in veterans with symptoms of post-traumatic stress.

scientific article

Individual differences in resting-state functional connectivity with the executive network: support for a cerebellar role in anxiety vulnerability

scientific article

Individuals with posttraumatic stress disorder show a selective deficit in generalization of associative learning.

scientific article published on 30 July 2012

Interleukin-1beta as a mechanism for stress-induced startle suppression in females

scientific article published in July 2006

Investigating the Role of Hippocampal BDNF in Anxiety Vulnerability Using Classical Eyeblink Conditioning

scientific article published on 24 July 2015

Learning to obtain reward, but not avoid punishment, is affected by presence of PTSD symptoms in male veterans: empirical data and computational model

scientific article

Long-lasting suppression of acoustic startle response after mild traumatic brain injury.

scientific article

Low doses of interleukin-1beta improve the leverpress avoidance performance of Sprague-Dawley rats

scientific article published in September 2003

Medial septum-diagonal band of Broca (MSDB) GABAergic regulation of hippocampal acetylcholine efflux is dependent on cognitive demands

scientific article published on January 2014

Mild interoceptive stressors affect learning and reactivity to contextual cues: toward understanding the development of unexplained illnesses.

scientific article published in August 2005

Noncholinergic lesions of the medial septum impair sequential learning of different spatial locations.

scientific article published on January 2007

Paired-housing selectively facilitates within-session extinction of avoidance behavior, and increases c-Fos expression in the medial prefrontal cortex, in anxiety vulnerable Wistar-Kyoto rats.

scientific article published on 24 May 2016

Persistent neuroendocrine changes in multiple hormonal axes after a single or repeated stressor exposures

scientific article published on 01 November 2000

Persistent plasma cholesterol elevations are produced by one or three stressor exposures in rats fed a normal laboratory diet

scientific article published on 01 June 1993

Persistent stress-induced sensitization of adrenocortical and startle responses

scientific article published on 01 November 1994

Preclinical investigation of the functional effects of memantine and memantine combined with galantamine or donepezil.

scientific article published on 22 November 2006

Proinflammatory cytokines differentially affect leverpress avoidance acquisition in rats

scientific article published in August 2004

Rapid avoidance acquisition in Wistar-Kyoto rats.

scientific article published on 18 April 2008

Relationship between abnormal cholesterol synthesis and retarded learning in rats ⬇️

scientific article published on July 1, 1998

Repeated stress persistently elevates morning, but not evening, plasma corticosterone levels in male rats

scientific article published in February 1994

Startle suppression after mild traumatic brain injury is associated with an increase in pro-inflammatory cytokines, reactive gliosis and neuronal loss in the caudal pontine reticular nucleus

scientific article published on 9 January 2017

Stress interacts with peripheral cholinesterase inhibitors to cause central nervous system effects.

scientific article published in May 2003

Stress-Related Mental Health Symptoms in Coast Guard: Incidence, Vulnerability, and Neurocognitive Performance

scientific article published on 14 September 2017

Stress-induced reductions of sensory reactivity in female rats depend on ovarian hormones and the application of a painful stressor.

scientific article published in May 2005

Testing the role of reward and punishment sensitivity in avoidance behavior: a computational modeling approach

scientific article

The contribution of stressor intensity, duration, and context to the stress-induced facilitation of associative learning

scientific article published in July 1997

US alone trials presented during acquisition do not disrupt classical eyeblink conditioning: Empirical and computational findings.

scientific article published on 17 October 2017

Uncertainty of trial timing enhances acquisition of conditioned eyeblinks in anxiety vulnerable individuals.

scientific article published on 9 February 2016

Vagal activity predicts eyeblink conditioning in human subjects

scientific article published in March 1997

Vulnerability factors in anxiety determined through differences in active-avoidance behavior.

scientific article published on 9 April 2010

Vulnerability factors in anxiety: Strain and sex differences in the use of signals associated with non-threat during the acquisition and extinction of active-avoidance behavior.

scientific article

Watch what I do, not what I say I do: Computer-based avatars to assess behavioral inhibition, a vulnerability factor for anxiety disorders.

scientific article

Why trace and delay conditioning are sometimes (but not always) hippocampal dependent: a computational model

scientific article published on 23 November 2012

Wistar-Kyoto rats as an animal model of anxiety vulnerability: support for a hypervigilance hypothesis

scientific article

List of works by Richard J. Servatius

A chronic stress state in rats: effects of repeated stress on basal corticosterone and behavior

A comparison of the effects of repeated stressor exposures and corticosterone injections on plasma cholesterol, thyroid hormones and corticosterone levels in rats

A model of amygdala-hippocampal-prefrontal interaction in fear conditioning and extinction in animals

A stress-induced anxious state in male rats: corticotropin-releasing hormone induces persistent changes in associative learning and startle reactivity.

Absence of "Warm-Up" during Active Avoidance Learning in a Rat Model of Anxiety Vulnerability: Insights from Computational Modeling.

Acquired equivalence in U.S. veterans with symptoms of posttraumatic stress: reexperiencing symptoms are associated with greater generalization

Acquisition and extinction of human avoidance behavior: attenuating effect of safety signals and associations with anxiety vulnerabilities

Altered activity of the medial prefrontal cortex and amygdala during acquisition and extinction of an active avoidance task.

Avoidance as expectancy in rats: sex and strain differences in acquisition

Avoidance perseveration during extinction training in Wistar-Kyoto rats: an interaction of innate vulnerability and stressor intensity.

Behavioral inhibition and PTSD symptoms in veterans.

Behaviorally inhibited individuals demonstrate significantly enhanced conditioned response acquisition under non-optimal learning conditions.

Behaviorally inhibited temperament is associated with severity of post-traumatic stress disorder symptoms and faster eyeblink conditioning in veterans

Behaviourally inhibited temperament and female sex, two vulnerability factors for anxiety disorders, facilitate conditioned avoidance (also) in humans.

Blocking cholesterol synthesis impairs acquisition of the classically conditioned eyeblink response

Brain and Serum Androsterone Is Elevated in Response to Stress in Rats with Mild Traumatic Brain Injury.

Brief intermittent light stimulation disrupts saccadic oculomotor control.

Cardiovascular evaluation of electronic control device exposure in law enforcement trainees: a multisite study.

Cerebellar response to familiar and novel stimuli: An fMRI study.

Cholinergic overstimulation supports conditioned-facilitated startle but not conditioned hyperalgesia.

Classical and instrumental conditioning of eyeblink responses in Wistar-Kyoto and Sprague-Dawley rats.

Cytokine levels during pregnancy influence immunological profiles and neurobehavioral patterns of the offspring.

Damage of GABAergic neurons in the medial septum impairs spatial working memory and extinction of active avoidance: effects on proactive interference.

Deficient proactive interference of eyeblink conditioning in Wistar-Kyoto rats.

Delayed startle sensitization distinguishes rats exposed to one or three stress sessions: further evidence toward an animal model of PTSD

Developmental sensitivity of associative learning to cholesterol synthesis inhibitors.

Differential effects of progesterone and medroxyprogesterone on delay eyeblink conditioning in ovariectomized rats.

Dysfunction in amygdala-prefrontal plasticity and extinction-resistant avoidance: A model for anxiety disorder vulnerability

Editorial: Avoidance: From Basic Science to Psychopathology.

Effect of life in a constant light environment on the course of hypertension in Dahl rats

Effects of inescapable stress and treatment with pyridostigmine bromide on plasma butyrylcholinesterase and the acoustic startle response in rats

Effects of psychotropic agents on extinction of lever-press avoidance in a rat model of anxiety vulnerability.

Effects of stress on nonassociative learning processes in male and female rats

Enhanced avoidance learning in behaviorally inhibited young men and women

Enhanced conditioned eyeblink response acquisition and proactive interference in anxiety vulnerable individuals ⬇️

Enhanced glutamatergic neurotransmission facilitates classical conditioning in the freely moving rat.

Exaggerated acquisition and resistance to extinction of avoidance behavior in treated heroin-dependent men

Exposure to morphine-associated cues increases mu opioid receptor mRNA expression in the nucleus accumbens of Wistar Kyoto rats

Eyeblink conditioning in the freely moving rat: square-wave stimulation as the unconditioned stimulus

Facilitated acquisition of eyeblink conditioning in those vulnerable to anxiety disorders.

Facilitated acquisition of standard but not long delay classical eyeblink conditioning in behaviorally inhibited adolescents

Facilitated acquisition of the classically conditioned eyeblink response in active duty military expressing posttraumatic stress disorder symptoms

Facilitated acquisition of the classically conditioned eyeblink response in females is augmented in those taking oral contraceptives

Facilitated acquisition of the classically conditioned eyeblink response in male rats after systemic IL-1beta.

Facilitated acquisition of the classically conditioned eyeblink response in women taking oral contraceptives.

GABAergic neurons in the medial septum-diagonal band of Broca (MSDB) are important for acquisition of the classically conditioned eyeblink response

ITI-Signals and Prelimbic Cortex Facilitate Avoidance Acquisition and Reduce Avoidance Latencies, Respectively, in Male WKY Rats

Impaired associative learning in chronic fatigue syndrome ⬇️

Increased generalization of learned associations is related to re-experiencing symptoms in veterans with symptoms of post-traumatic stress.

Individual differences in resting-state functional connectivity with the executive network: support for a cerebellar role in anxiety vulnerability

Individuals with posttraumatic stress disorder show a selective deficit in generalization of associative learning.

Interleukin-1beta as a mechanism for stress-induced startle suppression in females

Investigating the Role of Hippocampal BDNF in Anxiety Vulnerability Using Classical Eyeblink Conditioning

Learning to obtain reward, but not avoid punishment, is affected by presence of PTSD symptoms in male veterans: empirical data and computational model

Long-lasting suppression of acoustic startle response after mild traumatic brain injury.

Low doses of interleukin-1beta improve the leverpress avoidance performance of Sprague-Dawley rats

Medial septum-diagonal band of Broca (MSDB) GABAergic regulation of hippocampal acetylcholine efflux is dependent on cognitive demands

Mild interoceptive stressors affect learning and reactivity to contextual cues: toward understanding the development of unexplained illnesses.

Noncholinergic lesions of the medial septum impair sequential learning of different spatial locations.

Paired-housing selectively facilitates within-session extinction of avoidance behavior, and increases c-Fos expression in the medial prefrontal cortex, in anxiety vulnerable Wistar-Kyoto rats.

Persistent neuroendocrine changes in multiple hormonal axes after a single or repeated stressor exposures

Persistent plasma cholesterol elevations are produced by one or three stressor exposures in rats fed a normal laboratory diet

Persistent stress-induced sensitization of adrenocortical and startle responses

Preclinical investigation of the functional effects of memantine and memantine combined with galantamine or donepezil.

Proinflammatory cytokines differentially affect leverpress avoidance acquisition in rats

Rapid avoidance acquisition in Wistar-Kyoto rats.

Relationship between abnormal cholesterol synthesis and retarded learning in rats ⬇️

Repeated stress persistently elevates morning, but not evening, plasma corticosterone levels in male rats

Startle suppression after mild traumatic brain injury is associated with an increase in pro-inflammatory cytokines, reactive gliosis and neuronal loss in the caudal pontine reticular nucleus

Stress interacts with peripheral cholinesterase inhibitors to cause central nervous system effects.

Stress-Related Mental Health Symptoms in Coast Guard: Incidence, Vulnerability, and Neurocognitive Performance

Stress-induced reductions of sensory reactivity in female rats depend on ovarian hormones and the application of a painful stressor.

Testing the role of reward and punishment sensitivity in avoidance behavior: a computational modeling approach

The contribution of stressor intensity, duration, and context to the stress-induced facilitation of associative learning

US alone trials presented during acquisition do not disrupt classical eyeblink conditioning: Empirical and computational findings.

Uncertainty of trial timing enhances acquisition of conditioned eyeblinks in anxiety vulnerable individuals.

Vagal activity predicts eyeblink conditioning in human subjects

Vulnerability factors in anxiety determined through differences in active-avoidance behavior.

Vulnerability factors in anxiety: Strain and sex differences in the use of signals associated with non-threat during the acquisition and extinction of active-avoidance behavior.