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List of works by Scott Kopetz

"Right drug for the right patient": hurdles and the path forward in colorectal cancer.

scientific article published on January 2013

5-fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits

scientific article published on 21 October 2015

A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer.

scientific article

A feasibility study of returning clinically actionable somatic genomic alterations identified in a research laboratory.

scientific article published on 8 March 2017

A multicenter, multinational analysis of mitomycin C in refractory metastatic colorectal cancer.

scientific article published on 11 February 2012

A novel patient derived orthotopic xenograft model of gastro-esophageal junction cancer: Key platform for translational discoveries

scientific article published on 01 June 2018

A novel patient-derived orthotopic xenograft model of esophageal adenocarcinoma provides a platform for translational discoveries

scientific article published on 17 December 2019

A phase II study of UFT with leucovorin administered as a twice daily schedule in the treatment of patients with metastatic colorectal cancer.

scientific article published on 12 August 2008

A population-based comparison of adenocarcinoma of the large and small intestine: insights into a rare disease

scientific article published on 21 December 2011

A retrospective study of ampullary adenocarcinomas: overall survival and responsiveness to fluoropyrimidine-based chemotherapy ⬇️

scientific article published on May 22, 2013

ALDH Activity Selectively Defines an Enhanced Tumor-Initiating Cell Population Relative to CD133 Expression in Human Pancreatic Adenocarcinoma ⬇️

scientific article published on June 13, 2011

APC and PIK3CA Mutational Cooperativity Predicts Pathologic Response and Survival in Patients Undergoing Resection for Colorectal Liver Metastases

scientific article published on 4 April 2017

Accelerating Therapeutic Development through Innovative Trial Design in Colorectal Cancer.

scientific article published on 27 February 2018

Adjuvant chemotherapy with FOLFOX for primary colorectal cancer is associated with increased somatic gene mutations and inferior survival in patients undergoing hepatectomy for metachronous liver metastases

scientific article published on October 2012

Aggressive combined modality therapy for recurrent colorectal cancer involving the duodenum and pancreas: a report of 5 cases

scientific article published on 01 September 2008

Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA

scientific article published on 16 October 2015

Antitumor Activity of BRAF Inhibitor Vemurafenib in Preclinical Models of BRAF-Mutant Colorectal Cancer ⬇️

scientific article published on December 16, 2011

Antitumor effects of cyclin dependent kinase 9 inhibition in esophageal adenocarcinoma

scientific article

Applying Precision to the Management of BRAF-Mutant Metastatic Colorectal Cancer

scientific article published on 05 September 2020

Arginine methylation of EGFR: a new biomarker for predicting resistance to anti-EGFR treatment

scientific article published in December 2017

Association between KRAS mutation and lung metastasis in advanced colorectal cancer

scientific article published on 23 December 2014

Association of CpG island methylator phenotype and EREG/AREG methylation and expression in colorectal cancer.

scientific article

Association of SMAD4 mutation with patient demographics, tumor characteristics, and clinical outcomes in colorectal cancer

scientific article

BRAF inhibitors in clinical oncology ⬇️

scientific article published on April 2, 2013

BRAF inhibitors: experience in thyroid cancer and general review of toxicity

scientific article

BRAF mutant colorectal cancer as a distinct subset of colorectal cancer: clinical characteristics, clinical behavior, and response to targeted therapies

scientific article

BRAF-Directed Therapy in Metastatic Colorectal Cancer

scientific article published on May 2016

Barriers to Integrating Gene Profiling for Stage II Colon Cancer

scientific article published on 01 December 2009

Bevacizumab combined with capecitabine and oxaliplatin in patients with advanced adenocarcinoma of the small bowel or ampulla of vater: A single-center, open-label, phase 2 study.

scientific article

Beyond VEGF: inhibition of the fibroblast growth factor pathway and antiangiogenesis

scientific article

Bioactive lipid metabolism in platelet "first responder" and cancer biology

scientific article published on 01 September 2018

Biomarkers in colorectal liver metastases

scientific article published on 26 March 2018

Blood neutrophil-to-lymphocyte ratio predicts survival in patients with colorectal liver metastases treated with systemic chemotherapy.

scientific article published on 8 January 2009

Blood-based tests for colorectal cancer screening: do they threaten the survival of the FIT test?

scientific article

CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer

scientific article published on 24 June 2013

CT findings of response and recurrence, independent of change in tumor size, in colorectal liver metastasis treated with bevacizumab.

scientific article published on December 2011

Can Microsatellite Status of Colorectal Cancer Be Reliably Assessed after Neoadjuvant Therapy?

scientific article published on 18 May 2017

Cancer classification using the Immunoscore: a worldwide task force

scientific article

Cancer in silico drug discovery: a systems biology tool for identifying candidate drugs to target specific molecular tumor subtypes

scientific article

Challenges and strategies for identifying biomarkers for colorectal cancer

scientific article published on January 2013

Characterizing the patterns of clonal selection in circulating tumor DNA from patients with colorectal cancer refractory to anti-EGFR treatment

scientific article

Chemotherapy with 5-fluorouracil and a platinum compound improves outcomes in metastatic small bowel adenocarcinoma.

scientific article published in October 2008

Circulating DNA Demonstrates Convergent Evolution and Common Resistance Mechanisms during Treatment of Colorectal Cancer.

scientific article

Circulating Tumor DNA-Defined Minimal Residual Disease in Solid Tumors: Opportunities to Accelerate the Development of Adjuvant Therapies

article

Circulating tumor markers: harmonizing the yin and yang of CTCs and ctDNA for precision medicine.

scientific article published on 19 December 2016

Classifying colorectal cancer by tumor location rather than sidedness highlights a continuum in mutation profiles and Consensus Molecular Subtypes

scientific article published on 27 November 2017

Clinical utility of circulating cell-free DNA in advanced colorectal cancer

scientific article published on 29 August 2017

Clinical, Pathological, and Molecular Characteristics of CpG Island Methylator Phenotype in Colorectal Cancer: A Systematic Review and Meta-analysis

scientific article published on 30 July 2018

Clinicopathologic characteristics and gene expression analyses of non-KRAS 12/13, RAS-mutated metastatic colorectal cancer

scientific article

Colorectal premalignancy is associated with consensus molecular subtypes 1 and 2

scientific article published on 01 October 2018

Combined BRAF and MEK Inhibition With Dabrafenib and Trametinib in BRAF V600-Mutant Colorectal Cancer.

scientific article

Combined targeting of STAT3/NF-κB/COX-2/EP4 for effective management of pancreatic cancer.

scientific article published on 11 February 2014

Commentary: Practice Patterns and Potential Impact on Quality Measures for a Practicing Physician ⬇️

scientific article published on September 1, 2009

Comparison of early radiological predictors of outcome in patients with colorectal cancer with unresectable hepatic metastases treated with bevacizumab.

scientific article published on 30 October 2017

Comparison of prognostic genomic predictors in colorectal cancer.

scientific article

Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer

scientific article published on 4 January 2017

Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer

scientific article published on 01 March 2017

Consensus statement on essential patient characteristics in systemic treatment trials for metastatic colorectal cancer: Supported by the ARCAD Group

scientific article published on 22 June 2018

Convergence of nanotechnology and cancer prevention: are we there yet?

scientific article

Coordination of care in colon cancer

scientific article published on 04 June 2015

Correction to: Accelerating Therapeutic Development through Innovative Trial Design in Colorectal Cancer

scientific article published on 23 April 2018

Current and Future Approaches to Target the Epidermal Growth Factor Receptor and Its Downstream Signaling in Metastatic Colorectal Cancer.

scientific article published on 29 May 2015

Current companion diagnostics in advanced colorectal cancer; getting a bigger and better piece of the pie

scientific article published on February 2017

Cytokine profile and prognostic significance of high neutrophil-lymphocyte ratio in colorectal cancer.

scientific article

Deep sequencing of circulating tumor DNA detects molecular residual disease and predicts recurrence in gastric cancer

scientific article published on 11 May 2020

Don’t blame the messenger: lessons learned for cancer mRNA vaccines during the COVID-19 pandemic

scientific article published in 2022

Dual Inhibition of EGFR and c-Src by Cetuximab and Dasatinib Combined with FOLFOX Chemotherapy in Patients with Metastatic Colorectal Cancer

scientific article

Durable Clinical Benefit With Nivolumab Plus Ipilimumab in DNA Mismatch Repair-Deficient/Microsatellite Instability-High Metastatic Colorectal Cancer

scientific article

Durable complete responses in metastatic colorectal cancer treated with chemotherapy alone.

scientific article published on 24 April 2011

Early-Onset Signet-Ring Cell Adenocarcinoma of the Colon: A Case Report and Review of the Literature.

scientific article published on 23 February 2017

Efficacy of Sym004 in Patients With Metastatic Colorectal Cancer With Acquired Resistance to Anti-EGFR Therapy and Molecularly Selected by Circulating Tumor DNA Analyses: A Phase 2 Randomized Clinical Trial

scientific article published on 8 February 2018

Embryonic origin of primary colon cancer predicts survival in patients undergoing ablation for colorectal liver metastases.

scientific article published on 29 January 2017

Emerging drugs for colorectal cancer

scientific article published on 01 December 2008

Endothelial function, oxidative stress and inflammatory studies in chronic coronary slow flow phenomenon patients

scientific article published on 13 April 2012

Epithelial-mesenchymal transitioned circulating tumor cells capture for detecting tumor progression

scientific article

Evaluating for Pseudoprogression in Colorectal and Pancreatic Tumors Treated With Immunotherapy

scientific article published on 17 April 2018

Examining plasma microRNA markers for colorectal cancer at different stages.

scientific article published on 04 February 2016

Expanded RAS: refining the patient population

scientific article

FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma.

scientific article

FXR silencing in human colon cancer by DNA methylation and KRAS signaling.

scientific article published on 31 October 2013

Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials

scientific article

From multidisciplinary to personalized treatment of colorectal liver metastases: 4 reasons to consider RAS.

scientific article published on 19 September 2013

Gene expression profiling of ampullary carcinomas classifies ampullary carcinomas into biliary-like and intestinal-like subtypes that are prognostic of outcome

scientific article published on 11 June 2013

Genome-wide discovery and identification of a novel miRNA signature for recurrence prediction in stage II and III colorectal cancer.

scientific article published on 7 March 2018

Genomic analysis of exceptional responder to regorafenib in treatment-refractory metastatic rectal cancer: a case report and review of the literature

scientific article published on 3 June 2017

Genomic classifier ColoPrint predicts recurrence in stage II colorectal cancer patients more accurately than clinical factors

scientific article

Genomic landscape associated with potential response to anti-CTLA-4 treatment in cancers.

scientific article published on 19 October 2017

Genomic landscape of cell-free DNA in patients with colorectal cancer.

scientific article

Global and targeted serum metabolic profiling of colorectal cancer progression.

scientific article published on 22 June 2017

Hidden biases in an observational study of bevacizumab beyond progression

scientific article published on 2 March 2009

High survival rate after two-stage resection of advanced colorectal liver metastases: response-based selection and complete resection define outcome

scientific article

High-Grade Neuroendocrine Colorectal Carcinomas: A Retrospective Study of 100 Patients

scientific article published on 29 December 2015

Hurdles and complexities of codon 13 KRAS mutations

scientific article published on 27 August 2012

Hyperfractionated accelerated reirradiation for rectal cancer: An analysis of outcomes and toxicity

scientific article published on 03 January 2017

Immune Profiling of Premalignant Lesions in Patients With Lynch Syndrome.

scientific article

Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancer

scientific article

Impact of Prior Hepatectomy History on Local Tumor Progression after Percutaneous Ablation of Colorectal Liver Metastases

scientific article published on 27 January 2018

Impact of RAS Mutations in Metastatic Colorectal Cancer After Potentially Curative Resection: Does Site of Metastases Matter?

scientific article published on 25 October 2017

Impact of Recurrence and Salvage Surgery on Survival After Multidisciplinary Treatment of Rectal Cancer.

scientific article published on 28 June 2017

Impact of multimodal therapy in locally recurrent rectal cancer

scientific article

Incidental germline variants in 1000 advanced cancers on a prospective somatic genomic profiling protocol

scientific article published on 19 January 2016

Individualized Treatment Sequencing Selection Contributes to Optimized Survival in Patients with Rectal Cancer and Synchronous Liver Metastases

scientific article published on 19 September 2017

Integrated safety summary for trifluridine/tipiracil (TAS-102).

scientific article published on 24 November 2017

Intratumoral heterogeneity: Role of differentiation in a potentially lethal phenotype of testicular cancer

scientific article

Is complete liver resection without resection of synchronous lung metastases justified?

scientific article published on 06 November 2014

Is resection of colorectal liver metastases after a second-line chemotherapy regimen justified?

scientific article

Is there a role for adjuvant therapy in resected adenocarcinoma of the small intestine.

scientific article published in May 2010

Joint prognostic effect of obesity and chronic systemic inflammation in patients with metastatic colorectal cancer.

scientific article published on 14 May 2015

KRAS mutation in colorectal cancer metastases after adjuvant FOLFOX for the primary.

scientific article published on 27 September 2012

Local tumour progression after percutaneous ablation of colorectal liver metastases according to RAS mutation status.

scientific article published on 27 February 2017

Long-term survival and recurrence outcomes following surgery for distal rectal cancer.

scientific article

Loss of muscle mass during preoperative chemotherapy as a prognosticator for poor survival in patients with colorectal liver metastases

scientific article published on 06 September 2018

Margin Status Remains an Important Determinant of Survival After Surgical Resection of Colorectal Liver Metastases in the Era of Modern Chemotherapy ⬇️

scientific article published on June 1, 2013

Meta-analysis of KRAS mutations and survival after resection of colorectal liver metastases

scientific article published on 21 July 2015

Metastasis of cancer: when and how?

scientific article published in September 2017

Metastasis regulation by PPARD expression in cancer cells.

scientific article published on 12 January 2017

Molecular Biomarkers for the Evaluation of Colorectal Cancer.

scientific article published on 3 February 2017

Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology.

scientific article published on 6 February 2017

Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology.

scientific article published on 2 February 2017

Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and the American Society of Clinical Oncology.

scientific article

Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline Summary From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology.

scientific article published on 28 March 2017

Molecular profiling of patient-matched brain and extracranial melanoma metastases implicates the PI3K pathway as a therapeutic target

scientific article

Molecular spectrum of KRAS, NRAS, BRAF, PIK3CA, TP53, and APC somatic gene mutations in Arab patients with colorectal cancer: determination of frequency and distribution pattern.

scientific article published on December 2016

Multicenter retrospective analysis of metastatic colorectal cancer (CRC) with high-level microsatellite instability (MSI-H).

scientific article

Multicenter validation study of pathologic response and tumor thickness at the tumor‐normal liver interface as independent predictors of disease‐free survival after preoperative chemotherapy and surgery for colorectal liver metastases ⬇️

scientific article published on April 23, 2013

Multiplex KRASG12/G13 mutation testing of unamplified cell-free DNA from the plasma of patients with advanced cancers using droplet digital polymerase chain reaction

scientific article published on 19 December 2016

N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration

scientific article

Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study.

scientific article published on 19 July 2017

Nivolumab in the treatment of microsatellite instability high metastatic colorectal cancer

scientific article published on 23 February 2018

Non-V600 BRAF Mutations Define a Clinically Distinct Molecular Subtype of Metastatic Colorectal Cancer.

scientific article published on 9 May 2017

Non-coding RNAs in GI cancers: from cancer hallmarks to clinical utility

scientific article published on 07 February 2020

Oncogenic Kras drives invasion and maintains metastases in colorectal cancer.

scientific article published on 13 March 2017

Oncologic and Functional Hazards of Obesity Among Patients With Locally Advanced Rectal Cancer Following Neoadjuvant Chemoradiation Therapy.

scientific article

Ongoing and future directions in the management of metastatic colorectal cancer: Update on clinical trials

scientific article published on 10 March 2019

Optimal morphologic response to preoperative chemotherapy: an alternate outcome end point before resection of hepatic colorectal metastases

scientific article

Overcoming resistance to MAPK pathway inhibitors.

scientific article

Oxaliplatin-mediated increase in spleen size as a biomarker for the development of hepatic sinusoidal injury

scientific article

PI-3-Kinase inhibitors in colorectal cancer.

scientific article published on February 2011

PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response

scientific article published on 16 November 2015

Pan-Asian adapted ESMO consensus guidelines for the management of patients with metastatic colorectal cancer: a JSMO-ESMO initiative endorsed by CSCO, KACO, MOS, SSO and TOS.

scientific article published on 16 November 2017

Partial splenic embolization for cancer patients with thrombocytopenia requiring systemic chemotherapy

scientific article

Pathologic response to preoperative chemotherapy: a new outcome end point after resection of hepatic colorectal metastases.

scientific article published on 20 October 2008

Phase 1 study of TAS-102 administered once daily on a 5-day-per-week schedule in patients with solid tumors.

scientific article published on 5 June 2008

Phase I clinical study of three times a day oral administration of TAS-102 in patients with solid tumors.

scientific article

Phase I/II study of azacitidine and capecitabine/oxaliplatin (CAPOX) in refractory CIMP-high metastatic colorectal cancer: evaluation of circulating methylated vimentin

scientific article published on 16 August 2016

Phase II study of DFP-10917, a deoxycytidine analog, given by 14-day continuous intravenous infusion for chemotherapy-refractory advanced colorectal cancer

scientific article published on 13 June 2018

Phase II study of capecitabine and oxaliplatin for advanced adenocarcinoma of the small bowel and ampulla of Vater.

scientific article

Phase II study of nab-paclitaxel in refractory small bowel adenocarcinoma and CpG island methylator phenotype (CIMP)-high colorectal cancer.

scientific article published on 23 October 2017

Phase II study of saracatinib (AZD0530) in patients with previously treated metastatic colorectal cancer.

scientific article

Phase II trial of infusional fluorouracil, irinotecan, and bevacizumab for metastatic colorectal cancer: efficacy and circulating angiogenic biomarkers associated with therapeutic resistance

scientific article

Platelet "first responders" in wound response, cancer, and metastasis

scientific article

Platelet Metabolism and Other Targeted Drugs; Potential Impact on Immunotherapy.

scientific article

Platelet microparticles: small payloads with profound effects on tumor growth

scientific article published on 17 November 2017

Platelets and cancer: a casual or causal relationship: revisited.

scientific article

Platelets, circulating tumor cells, and the circulome.

scientific article published on 30 June 2017

Population pharmacokinetics and covariate analysis of Sym004, an antibody mixture against the epidermal growth factor receptor, in subjects with metastatic colorectal cancer and other solid tumors

scientific article published on 02 November 2019

Portal hypertension associated with oxaliplatin administration: clinical manifestations of hepatic sinusoidal injury

scientific article

Postoperative chemotherapy use after neoadjuvant chemoradiotherapy for rectal cancer: Analysis of Surveillance, Epidemiology, and End Results-Medicare data, 1998-2007

scientific article

Potential role of nuclear PD-L1 expression in cell-surface vimentin positive circulating tumor cells as a prognostic marker in cancer patients.

scientific article published on July 2016

Predictive and prognostic markers in colorectal cancer

scientific article published on 01 June 2011

Predictors of health-related quality of life and association with survival may identify colorectal cancer patients at high risk of poor prognosis.

scientific article published on 4 August 2016

Preoperative bevacizumab does not significantly increase postoperative complication rates in patients undergoing hepatic surgery for colorectal cancer liver metastases

scientific article published on 14 October 2008

Preoperative radiation dose escalation for rectal cancer using a concomitant boost strategy improves tumor downstaging without increasing toxicity: A matched-pair analysis

scientific article

Preoperative radiation therapy with concurrent capecitabine, bevacizumab, and erlotinib for rectal cancer: a phase 1 trial

scientific article published on 5 December 2013

Prognostic Implications of Mucinous Differentiation in Metastatic Colorectal Carcinoma Can Be Explained by Distinct Molecular and Clinicopathologic Characteristics

scientific article published on 17 July 2018

Prognostic factors after resection of colorectal liver metastases following preoperative second-line chemotherapy: Impact of RAS mutations

scientific article published on 5 March 2016

Prognostic gene expression signature associated with two molecularly distinct subtypes of colorectal cancer

scientific article

Prognostic impact of perihepatic lymph node metastases in patients with resectable colorectal liver metastases

scientific article published on 17 April 2018

Progression-free survival remains poor over sequential lines of systemic therapy in patients with BRAF-mutated colorectal cancer

scientific article

Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival.

scientific article

Pulmonary arteriovenous fistula in a patient with renal cell carcinoma

scientific article published in April 2007

Quantified pathologic response assessed as residual tumor burden is a predictor of recurrence-free survival in patients with rectal cancer who undergo resection after neoadjuvant chemoradiotherapy

scientific article published in October 2013

RAS Mutation is Associated with Unsalvageable Recurrence Following Hepatectomy for Colorectal Cancer Liver Metastases

scientific article published on 21 May 2018

RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases

scientific article published on October 2013

RAS mutations predict radiologic and pathologic response in patients treated with chemotherapy before resection of colorectal liver metastases.

scientific article

Recent developments in the treatment of metastatic colorectal cancer.

scientific article published on 29 June 2017

Relative Abundance of SARS-CoV-2 Entry Genes in the Enterocytes of the Lower Gastrointestinal Tract

scientific article published on 10 April 2020

Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents ⬇️

scientific article published on December 18, 2012

Retreatment with anti-EGFR based therapies in metastatic colorectal cancer: impact of intervening time interval and prior anti-EGFR response

scientific article published on 16 October 2015

Return to intended oncologic treatment (RIOT): a novel metric for evaluating the quality of oncosurgical therapy for malignancy.

scientific article published on 21 May 2014

Right Versus Left Colon Cancer Biology: Integrating the Consensus Molecular Subtypes

scientific article

SMAD4 gene mutation predicts poor prognosis in patients undergoing resection for colorectal liver metastases

scientific article published on 07 March 2018

Sacral insufficiency fractures after preoperative chemoradiation for rectal cancer: incidence, risk factors, and clinical course.

scientific article

Second-line chemotherapy use in metastatic colon cancer varies by disease responsiveness.

scientific article published on January 2008

Sequenced chemotherapy and surgery for potentially resectable colorectal liver metastases: a debate over goals of research and an approach while the jury remains out

scientific article published on 16 March 2010

Severe obesity prior to diagnosis limits survival in colorectal cancer patients evaluated at a large cancer centre

scientific article published on 17 December 2015

Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer.

scientific article published on 25 May 2017

Src activity is modulated by oxaliplatin and correlates with outcomes after hepatectomy for metastatic colorectal cancer.

scientific article

Src continues aging: current and future clinical directions.

scientific article published on December 2007

Streptococcus gallolyticus subsp. gallolyticus promotes colorectal tumor development.

scientific article published on 13 July 2017

Surgical strategies for synchronous colorectal liver metastases in 156 consecutive patients: classic, combined or reverse strategy?

scientific article

Survival benefit associated with surgical oophorectomy in patients with colorectal cancer metastatic to the ovary.

scientific article published on 26 January 2012

Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress

scientific article published on 21 April 2009

Systemic chemotherapy and two-stage hepatectomy for extensive bilateral colorectal liver metastases: perioperative safety and survival

scientific article published on 11 September 2007

Systemic cytotoxic and biologic therapies for colorectal cancer liver metastases: expert consensus statement.

scientific article published in February 2013

TMEM9 promotes intestinal tumorigenesis through vacuolar-ATPase-activated Wnt/β-catenin signalling

scientific article published on 29 October 2018

Targeting BRAF-Mutant Colorectal Cancer: Progress in Combination Strategies.

scientific article

Targeting CDK9 and MCL-1 by a new CDK9/p-TEFb inhibitor with and without 5-fluorouracil in esophageal adenocarcinoma

scientific article published on 25 July 2019

Targeting cyclin-dependent kinase 9 by a novel inhibitor enhances radiosensitization and identifies Axl as a novel downstream target in esophageal adenocarcinoma

scientific article published on 23 July 2019

The Addition of Bevacizumab to Oxaliplatin-Based Chemotherapy: Impact Upon Hepatic Sinusoidal Injury and Thrombocytopenia

scientific article published on 15 January 2018

The Promise of Patient-Derived Xenografts: The Best Laid Plans of Mice and Men ⬇️

scientific article published on August 21, 2012

The SRC family of protein tyrosine kinases: a new and promising target for colorectal cancer therapy.

scientific article

The association of alternate VEGF ligands with resistance to anti-VEGF therapy in metastatic colorectal cancer

scientific article

The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis

scientific article

The consensus molecular subtypes of colorectal cancer

scientific article

The potential role of platelets in the consensus molecular subtypes of colorectal cancer.

scientific article published on 6 July 2017

The requirement for freshly isolated human colorectal cancer (CRC) cells in isolating CRC stem cells

scientific article published on 23 December 2014

The somatic mutation landscape of premalignant colorectal adenoma.

scientific article

Topoisomerase IIα in chromosome instability and personalized cancer therapy.

scientific article

Towards the introduction of the 'Immunoscore' in the classification of malignant tumours

scientific article

Tumor Microenvironment in Gene Signatures: Critical Biology or Confounding Noise?

scientific article published on 22 June 2016

Two phase I, pharmacokinetic, and pharmacodynamic studies of DFP-10917, a novel nucleoside analog with 14-day and 7-day continuous infusion schedules

scientific article published on 18 April 2018

Untying the gordion knot of targeting MET in cancer

scientific article published on 26 April 2018

Use of Research Biopsies in Clinical Trials: Are Risks and Benefits Adequately Discussed? ⬇️

scientific article published on November 5, 2012

Utility of a molecular prescreening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials.

scientific article

Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers

scientific article published on 21 October 2020

Why a One Size Fits All Approach to RAS Might Not Fit Colorectal Cancer

scientific article published in April 2017

ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal-Anal Task Forces whitepaper

scientific article published on 06 July 2020

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