List of works by Mony J de Leon

(18)F-FDG PET database of longitudinally confirmed healthy elderly individuals improves detection of mild cognitive impairment and Alzheimer's disease.

scientific article published on 15 June 2007

18F-2-deoxy-2-fluoro-D-glucose as a tracer in the positron emission tomographic study of senile dementia.

scientific article

A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease

scientific article

A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice

scientific article published on 08 February 2007

APOE-by-sex interactions on brain structure and metabolism in healthy elderly controls

scientific article

Abnormal cortisol response in Alzheimer's disease linked to hippocampal atrophy

scientific article published in The Lancet

Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders

scientific article

Abnormal temporal lobe response in Alzheimer's disease during cognitive processing as measured by 11C-2-deoxy-D-glucose and PET.

scientific article published in April 1987

Absence of hippocampal volume differences in survivors of the Nazi Holocaust with and without posttraumatic stress disorder

scientific article

Age and diagnostic performance of Alzheimer disease CSF biomarkers.

scientific article published on February 2012

Age-related changes in brain: II. Positron emission tomography of frontal and temporal lobe glucose metabolism in normal subjects

scientific article published on 01 January 1995

Altered glucose metabolism in microvessels from patients with Alzheimer's disease

scientific article published on 01 July 1989

Altered patterns of positron-emission tomography glucose metabolism in Alzheimer patients with microvascular white matter disease.

scientific article

Alternative normalization methods demonstrate widespread cortical hypometabolism in untreated de novo Parkinson's disease.

scientific article published on June 2012

Alzheimer disease: measuring loss of cerebral gray matter with MR imaging.

scientific article

Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects

scientific article

Alzheimer's disease markers, hypertension, and gray matter damage in normal elderly

scientific article

Amyloid and metabolic positron emission tomography imaging of cognitively normal adults with Alzheimer's parents

scientific article

An entorhinal cortex sulcal pattern is associated with Alzheimer's disease

scientific article published on March 2009

Anteroposterior hippocampal metabolic heterogeneity: three-dimensional multivoxel proton 1H MR spectroscopic imaging--initial findings

scientific article

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans

scientific article published on 16 February 2012

Associations of lifestyle and vascular risk factors with Alzheimer's brain biomarker changes during middle age: a 3-year longitudinal study in the broader New York City area

scientific article published on 25 November 2018

Atrophy of hippocampal formation subdivisions correlates with stage and duration of Alzheimer disease.

scientific article published in July 1995

Atrophy rate in medial temporal lobe during progression of Alzheimer disease.

scientific article published in December 2004

Basal forebrain septal nuclei are enlarged in healthy subjects prior to the development of Alzheimer's disease.

scientific article published on 2 February 2018

Bayesian applications to longitudinal analysis on medical data with discrete outcomes

scientific article

Biomarkers for the early diagnosis of Alzheimer's disease.

scientific article published in March 2006

Blood pressure decrease correlates with tau pathology and memory decline in hypertensive elderly

scientific article published on 19 August 2013

Brain Atrophy of Secondary REM-Sleep Behavior Disorder in Neurodegenerative Disease

scientific article published on 05 April 2015

Brain glucose hypometabolism and oxidative stress in preclinical Alzheimer's disease

scientific article published on December 2008

Brain imaging of cognitively normal individuals with 2 parents affected by late-onset AD.

scientific article published on 12 February 2014

CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment.

scientific article published in July 2009

CT prognostic criteria of survival after malignant glioma surgery ⬇️

scientific article published on May 1, 1983

Carbonic anhydrase inhibition selectively prevents amyloid β neurovascular mitochondrial toxicity

scientific article published on 05 June 2018

Central amine metabolism in Alzheimer's disease: in vivo relationship to cognitive deficit

scientific article published on 01 January 1981

Cerebellar atrophy in Alzheimer's disease-clinicopathological correlations.

scientific article

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

scientific article published on 27 October 2017

Cerebrovascular reactivity to carbon dioxide in Alzheimer's disease

scientific article

Challenges associated with biomarker-based classification systems for Alzheimer's disease

scientific article published on 21 April 2018

Changes in brain functional homogeneity in subjects with Alzheimer's disease.

scientific article published on February 2002

Cholesterol in neurologic disorders of the elderly: stroke and Alzheimer's disease

scientific article published on September 2004

Clearance systems in the brain--implications for Alzheimer diseaser.

scientific article

Clearance systems in the brain-implications for Alzheimer disease

scientific article

Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer's disease

scientific article

Combining early markers strongly predicts conversion from mild cognitive impairment to Alzheimer's disease

scientific article published on 23 August 2008

Comparison of the Brain Volume in Essential Tremor and Parkinson's Disease Tremor Using an Automated Segmentation Method

scientific article published on 29 April 2015

Computed tomography and positron emission transaxial tomography evaluations of normal aging and Alzheimer's disease.

scientific article published in September 1983

Computed tomography evaluations of brain-behavior relationships in senile dementia of the Alzheimer's type.

scientific article published in January 1980

Computed tomography in aging and senile dementia of the Alzheimer type.

scientific article published in January 1983

Computed tomography scans and negative symptoms in schizophrenia: chronic schizophrenics with negative symptoms and nonenlarged lateral ventricles.

scientific article

Correction: Perimenopause and emergence of an Alzheimer's bioenergetic phenotype in brain and periphery

scientific article published on 15 February 2018

Correlations between computerised tomographic changes and behavioural deficits in senile dementia ⬇️

scientific article published on October 20, 1979

Cortical laminar binding of PET amyloid and tau tracers in Alzheimer disease

scientific article

Cortisol levels during human aging predict hippocampal atrophy and memory deficits.

scientific article published on May 1998

Current Challenges for the Early Detection of Alzheimer's Disease: Brain Imaging and CSF Studies

scientific article

Declining brain glucose metabolism in normal individuals with a maternal history of Alzheimer disease

scientific article

Detection of amyloid plaques targeted by USPIO-Aβ1-42 in Alzheimer's disease transgenic mice using magnetic resonance microimaging

scientific article published on 19 January 2011

Detection of amyloid plaques targeted by bifunctional USPIO in Alzheimer's disease transgenic mice using magnetic resonance microimaging

scientific article

Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010.

scientific article published in March 2011

Different Relationship Between Systolic Blood Pressure and Cerebral Perfusion in Subjects With and Without Hypertension

scientific article published on 01 January 2019

Dilatation of the lateral part of the transverse fissure of the brain in Alzheimer's disease.

scientific article published in January 1993

Does mild cognitive impairment increase the risk of developing postoperative cognitive dysfunction?

scientific article

Early detection of Alzheimer's disease using neuroimaging

scientific article

Early detection of Alzheimer's disease with PET imaging.

scientific article published on 03 March 2010

Early marker for Alzheimer's disease: the atrophic hippocampus.

scientific article published in September 1989

Effects of memantine on cerebrospinal fluid biomarkers of neurofibrillary pathology

scientific article

Effects of naloxone in senile dementia: a double-blind trial.

scientific article published in March 1983

Effects of vascular risk factors, statins, and antihypertensive drugs on PiB deposition in cognitively normal subjects

scientific article published on 19 April 2016

Evaluation of Early Dementia (Mild Cognitive Impairment).

scientific article published on January 2010

FDG and Amyloid PET in Cognitively Normal Individuals at Risk for Late-Onset Alzheimer's Disease

scientific article

FDG-PET changes in brain glucose metabolism from normal cognition to pathologically verified Alzheimer's disease

scientific article published on 14 January 2009

Familial nature of Alzheimer's disease?

scientific article published in November 1984

Fibrillar amyloid-beta affects neurofibrillary changes but only in neurons already involved in neurofibrillary degeneration.

scientific article published in June 2001

Framingham cardiovascular risk profile correlates with impaired hippocampal and cortical vasoreactivity to hypercapnia

scientific article

Global Deterioration Scale (GDS).

scientific article published in January 1988

Greater risk of Alzheimer's disease in older adults with insomnia

scientific article

Greater specificity for cerebrospinal fluid P-tau231 over P-tau181 in the differentiation of healthy controls from Alzheimer's disease

scientific article

Hippocampal atrophy in early Alzheimer's disease: anatomic specificity and validation.

scientific article published on January 1993

Hippocampal atrophy in normal aging. An association with recent memory impairment.

scientific article

Hippocampal blood flow in normal aging measured with arterial spin labeling at 3T

scientific article

Hippocampal cerebrospinal fluid spaces on MR imaging: Relationship to aging and Alzheimer disease.

scientific article

Hippocampal hypometabolism predicts cognitive decline from normal aging

scientific article published on 11 January 2007

Hippocampal volume losses in minimally impaired elderly.

scientific article published in January 1995

Hypometabolism and altered cerebrospinal fluid markers in normal apolipoprotein E E4 carriers with subjective memory complaints

scientific article published on 27 August 2007

Hypometabolism exceeds atrophy in presymptomatic early-onset familial Alzheimer's disease.

scientific article published in November 2006

Imaging and CSF studies in the preclinical diagnosis of Alzheimer's disease.

scientific article

Imaging and cerebrospinal fluid biomarkers in the search for Alzheimer's disease mechanisms

scientific article

Imaging markers for Alzheimer disease: which vs how

scientific article

Imaging the brain in dementia: expensive and futile?

scientific article published on November 1997

In vivo structural studies of the hippocampus in normal aging and in incipient Alzheimer's disease.

scientific article published on January 1996

Increased Alzheimer's risk during the menopause transition: A 3-year longitudinal brain imaging study

scientific article published in PLoS ONE

Increased fibrillar amyloid-{beta} burden in normal individuals with a family history of late-onset Alzheimer's

scientific article

Induction of c-fos immunoreactivity in tyrosine hydroxylase and phenylethanolamine-N-methyltransferase immunoreactive neurons of the medulla oblongata of the rat after phosphate-buffered saline load in the urethane-anaesthetized rat.

scientific article published in February 1993

Inflammation and Alzheimer's disease: possible role of periodontal diseases

scientific article published on 21 December 2007

Interaction between sleep-disordered breathing and apolipoprotein E genotype on cerebrospinal fluid biomarkers for Alzheimer's disease in cognitively normal elderly individuals

scientific article

Letter to the editor regarding: Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective

scientific article

Lifestyle and vascular risk effects on MRI-based biomarkers of Alzheimer's disease: a cross-sectional study of middle-aged adults from the broader New York City area.

scientific article published on 23 March 2018

Link between DYRK1A overexpression and several-fold enhancement of neurofibrillary degeneration with 3-repeat tau protein in Down syndrome

scientific article

Longitudinal CSF and MRI biomarkers improve the diagnosis of mild cognitive impairment.

scientific article published on 26 August 2005

Longitudinal CSF isoprostane and MRI atrophy in the progression to AD.

scientific article published on 14 November 2007

Longitudinal CT study of parenchymal brain changes in glioma survivors.

scientific article published in May 1988

Longitudinal course of normal aging and progressive dementia of the Alzheimer's type: a prospective study of 106 subjects over a 3.6 year mean interval.

scientific article published in January 1986

MR differential diagnosis of normal-pressure hydrocephalus and Alzheimer disease: significance of perihippocampal fissures.

scientific article published in May 1998

MRI assessment of neuropathology in a transgenic mouse model of Alzheimer's disease.

scientific article published in April 2004

MRI volume of the amygdala: a reliable method allowing separation from the hippocampal formation.

scientific article

Magnetic resonance and PET studies in the early diagnosis of Alzheimer's disease

scientific article

Magnetic resonance imaging improves cerebrospinal fluid biomarkers in the early detection of Alzheimer's disease

scientific article published on January 2009

Maternal age affects brain metabolism in adult children of mothers affected by Alzheimer's disease

scientific article

Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism

scholarly article

Maternal transmission of Alzheimer's disease: prodromal metabolic phenotype and the search for genes.

scientific article

Mediterranean Diet and Magnetic Resonance Imaging-Assessed Brain Atrophy in Cognitively Normal Individuals at Risk for Alzheimer's Disease.

scientific article

Mediterranean diet and 3-year Alzheimer brain biomarker changes in middle-aged adults.

scientific article published on 13 April 2018

Memantine decreases hippocampal glutamate levels: a magnetic resonance spectroscopy study

scientific article published on 07 February 2008

Midbrain atrophy in vascular Parkinsonism

scientific article

Mild cognitive impairment

scientific article published in The Lancet

Mild cognitive impairment (MCI): a historical perspective

scientific article published on 22 November 2007

Military-related risk factors for dementia

article published in 2018

Multicenter standardized 18F-FDG PET diagnosis of mild cognitive impairment, Alzheimer's disease, and other dementias

scientific article published on 20 February 2008

Novel pharmacologic approaches to the treatment of senile dementia of the Alzheimer's type (SDAT).

scientific article published on January 1983

Nutrient intake and brain biomarkers of Alzheimer's disease in at-risk cognitively normal individuals: a cross-sectional neuroimaging pilot study

scientific article

Nutrient patterns and brain biomarkers of Alzheimer's disease in cognitively normal individuals

scientific article

Obstructive Sleep Apnea Severity Affects Amyloid Burden in Cognitively Normal Elderly: A Longitudinal Study

scientific article published on 10 November 2017

Ordering of Alzheimer disease biomarkers

scientific article published in March 2012

Orexin-A is Associated with Increases in Cerebrospinal Fluid Phosphorylated-Tau in Cognitively Normal Elderly Subjects

scientific article published on 29 February 2016

Oxidative stress and amyloid-beta pathology in normal individuals with a maternal history of Alzheimer's

scientific article

Parenchymal CT correlates of senile dementia (Alzheimer disease): loss of gray-white matter discriminability.

scientific article published in May 1981

Perimenopause and emergence of an Alzheimer's bioenergetic phenotype in brain and periphery.

scientific article published on 10 October 2017

Periodontal disease associates with higher brain amyloid load in normal elderly

scientific article

Periodontal disease's contribution to Alzheimer's disease progression in Down syndrome

scientific article

Phosphorylated tau 231, memory decline and medial temporal atrophy in normal elders

scientific article

Physical Activity, Mediterranean Diet and Biomarkers-Assessed Risk of Alzheimer's: A Multi-Modality Brain Imaging Study

scientific article

Plasma and CSF biomarkers for the diagnosis of Alzheimer's disease in adults with Down syndrome: a cross-sectional study

scientific article published on 29 August 2018

Plasma tau complements CSF tau and P-tau in the diagnosis of Alzheimer's disease

scientific article published on 28 June 2019

Positron Emission Tomography in the Study of Aging and Senile Dementia

article

Positron emission tomographic studies of aging and Alzheimer disease.

scientific article published on May 1983

Positron emission tomography and computed tomography assessments of the aging human brain.

scientific article published in February 1984

Positron emission tomography in dementia

scientific article published on 01 January 1983

Positron emission tomography studies of normal aging: a replication of PET III and 18-FDG using PET VI and 11-CDG

scientific article published on 01 July 1987

Positron emission tomography with the deoxyglucose technique and the diagnosis of Alzheimer's disease.

scientific article

Posterior cingulate glucose metabolism, hippocampal glucose metabolism, and hippocampal volume in cognitively normal, late-middle-aged persons at 3 levels of genetic risk for Alzheimer disease

scientific article published on March 2013

Pre-clinical detection of Alzheimer's disease using FDG-PET, with or without amyloid imaging

scientific article published on January 2010

Precisely-Measured Hydration Status Correlates with Hippocampal Volume in Healthy Older Adults

scientific article published on 11 February 2019

Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment

scientific article published on 24 September 2007

Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/positron-emission tomography (FDG/PET).

scientific article

Prefrontal N-acetylaspartate and poststroke recovery: a longitudinal proton spectroscopy study.

scientific article published on March 2007

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

scientific article published on May 2015

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.

scientific article published on 27 March 2018

Principal axes and surface fitting methods for three-dimensional image registration

scientific article published on 01 November 1993

Quantitation, regional vulnerability, and kinetic modeling of brain glucose metabolism in mild Alzheimer's disease

scientific article published on 4 April 2007

Quantitative evaluation of tau PET tracers F-THK5351 and F-AV-1451 in Alzheimer's disease with standardized uptake value peak-alignment (SUVP) normalization

scholarly article by Jingyun Chen et al published July 2018 in European Journal of Nuclear Medicine and Molecular Imaging

Reduced Slow-Wave Sleep Is Associated with High Cerebrospinal Fluid Aβ42 Levels in Cognitively Normal Elderly.

scientific article published on 19 August 2016

Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly

scholarly article

Reduced glucose uptake and Aβ in brain regions with hyperintensities in connected white matter

scientific article

Reduced hippocampal metabolism in MCI and AD: automated FDG-PET image analysis.

scientific article published in June 2005

Reduced incidence of left-handedness in clinically diagnosed dementia of the Alzheimer type.

scientific article published in May 1986

Reduced mitochondria cytochrome oxidase activity in adult children of mothers with Alzheimer's disease

scientific article published on January 2011

Reduced retention of Pittsburgh compound B in white matter lesions

scientific article published on 21 October 2014

Regional analysis of FDG and PIB-PET images in normal aging, mild cognitive impairment, and Alzheimer's disease

scientific article published on 20 June 2008

Regional brain atrophy rate predicts future cognitive decline: 6-year longitudinal MR imaging study of normal aging

scientific article published on December 2003

Regional correlation of PET and CT in senile dementia of the Alzheimer type

scientific article published on 01 May 1983

Reply: Cerebrospinal Fluid, Hyposmia and Dementia in Alzheimer Disease: Insights from Dynamic PET and a Hypothesis

scientific article published on 9 February 2018

Resting-state glucose metabolism level is associated with the regional pattern of amyloid pathology in Alzheimer's disease

scientific article published on 17 March 2011

Robust and conventional neuropsychological norms: diagnosis and prediction of age-related cognitive decline

scientific article published on July 2008

Salivary cortisol day profiles in elderly with mild cognitive impairment.

scientific article published on October 2002

Seeing what Alzheimer saw.

scientific article published in February 2007

Self-reported obstructive sleep apnea, amyloid and tau burden, and Alzheimer's disease time-dependent progression

scientific article published on 08 October 2020

Sex differences in Alzheimer risk: Brain imaging of endocrine vs chronologic aging

scientific article published on 30 August 2017

Significance of age-related white matter lesions ⬇️

scientific article published on August 1, 1988

Sleep oscillation-specific associations with Alzheimer's disease CSF biomarkers: novel roles for sleep spindles and tau

scientific article published on 21 February 2019

Sleep-disordered breathing advances cognitive decline in the elderly

scientific article published on 15 April 2015

Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease.

scientific article

Structural brain changes in normal individuals with a maternal history of Alzheimer's

scientific article

Subjective memory complaints in aging are associated with elevated cortisol levels

scientific article published on November 2005

Subjective memory complaints: presence, severity and future outcome in normal older subjects

scientific article published on 17 July 2007

Subregional hippocampal atrophy predicts Alzheimer's dementia in the cognitively normal

scientific article

Survey of protocols for the manual segmentation of the hippocampus: preparatory steps towards a joint EADC-ADNI harmonized protocol

scientific article published on January 2011

TNF-alpha and antibodies to periodontal bacteria discriminate between Alzheimer's disease patients and normal subjects

scientific article published on 19 September 2009

The Global Deterioration Scale for assessment of primary degenerative dementia

article

The cerebrospinal fluid "Alzheimer profile": easily said, but what does it mean?

scientific article published on 8 April 2014

The concept of FDG-PET endophenotype in Alzheimer's disease.

scientific article published on June 2011

The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease

scientific article published on 24 October 2007

The histological validation of post mortem magnetic resonance imaging-determined hippocampal volume in Alzheimer's disease.

scientific article published in January 2000

The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes

scientific article

The nonlinear relationship between cerebrospinal fluid Aβ42 and tau in preclinical Alzheimer's disease

scientific article published on 7 February 2018

The pre-mild cognitive impairment, subjective cognitive impairment stage of Alzheimer's disease

scientific article published on January 2008

The radiologic prediction of Alzheimer disease: the atrophic hippocampal formation.

scientific article

The relationship between psychiatric assessments and cognitive test measures in mild to moderately cognitively impaired elderly [proceedings]

scientific article published in January 1981

The role of quantitative structural imaging in the early diagnosis of Alzheimer's disease

scientific article

The stage specific temporal course of Alzheimer's disease: functional and behavioral concomitants based upon cross-sectional and longitudinal observation.

scientific article published on January 1989

Therapeutic potential for peripheral clearance of misfolded brain proteins

scientific article published on 01 November 2018

Traumatic Brain Injury and Alzheimer's Disease: The Cerebrovascular Link

scientific article published on 30 January 2018

Twelve-month metabolic declines in probable Alzheimer's disease and amnestic mild cognitive impairment assessed using an empirically pre-defined statistical region-of-interest: findings from the Alzheimer's Disease Neuroimaging Initiative

scientific article

Two Year Outcomes, Cognitive and Behavioral Markers of Decline in Healthy, Cognitively Normal Older Persons with Global Deterioration Scale Stage 2 (Subjective Cognitive Decline with Impairment)

scientific article published on 01 January 2019

Vascular fibrosis and calcification in the hippocampus in aging, Alzheimer disease, and Down syndrome.

scientific article published on 28 November 2001

Visual rating of medial temporal lobe metabolism in mild cognitive impairment and Alzheimer's disease using FDG-PET.

scientific article published on 26 November 2005

Volumetric analysis of the pre-frontal regions: findings in aging and schizophrenia.

scientific article

Wandering and parietal signs in senile dementia of Alzheimer's type.

scientific article published in January 1984

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