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List of works by Bo Siesjö

A Method for Determining Blood Flow and Oxygen Consumption in the Rat Brain

scientific article published on January 1, 1976

A Paradoxical EEG Response during Combined Hypoxemia and Unilateral Carotid Artery Ligation in the Rat

scientific article published on December 1, 1972

A catecholamine-mediated increase in cerebral oxygen uptake during immobilisation stress in rats

scientific article published in January 1977

A hypothesis for the regulation of extracellular pH in the brain

scientific article published on May 1969

A metabolic basis for the selective vulnerability of neurons in status epilepticus

scientific article published on 01 July 1979

A mismatch between the abnormalities in diffusion- and susceptibility-weighted magnetic resonance imaging may represent an acute ischemic penumbra with misery perfusion

scientific article published on 12 February 2013

A new perspective on ischemic brain damage?

scientific article

A new theory for the regulation of the extracellular pH in the brain

scientific article published in August 1969

A novel neuroprotective compound FR901459 with dual inhibition of calcineurin and cyclophilins

scientific article published in January 2006

A technique for brain temperature control during ischemia, suitable for measurements with ion-sensitive microelectrodes.

scientific article published in October 1992

A venous outflow method for measurement of rapid changes of the cerebral blood flow and oxygen consumption in the rat.

scientific article

ADAMTS13 gene deletion enhances plasma high-mobility group box1 elevation and neuroinflammation in brain ischemia–reperfusion injury

scientific article published on January 3, 2012

Accumulation of calcium and loss of potassium in the hippocampus following transient cerebral ischemia: a proton microprobe study

scientific article published on 01 August 1988

Accumulation of calcium in substantia nigra lesions induced by status epilepticus. A microprobe analysis

scientific article published in April 1990

Acid-Base Relations in Arterial Blood and Cerebrospinal Fluid of the Unanesthetized Rat

scientific article published on 01 September 1967

Acid-base and lactate-pyruvate changes in brain and CSF in asphyxia and stagnant hypoxia

scientific article published in January 1968

Acid-base changes during complete brain ischemia

scientific article

Acid-base changes in the brain in nonrespiratory acidosis and alkalosis

scientific article published in January 1966

Acid-base homeostasis in the brain: physiology, chemistry, and neurochemical pathology

scientific article

Acidosis and ischemic brain damage.

scientific article published on July 1988

Acidosis enhances translocation of protein kinase C but not Ca2+/calmodulin-dependent protein kinase II to cell membranes during complete cerebral ischemia

scientific article published on 01 December 1999

Acidosis induced by hypercapnia exaggerates ischemic brain damage

scientific article

Acidosis promotes the permeability transition in energized mitochondria: implications for reperfusion injury

scientific article published in October 2001

Acidosis-induced ischemic brain damage: are free radicals involved?

scientific article published in July 1991

Acidosis-related brain damage.

scientific article

Acidosis-related damage.

scientific article published on January 1996

Activity of mitochondrial respiratory chain enzymes after transient focal ischemia in the rat

scientific article published on 01 November 1997

Adenosine and cyclic AMP in cerebral cortex of rats in hypoxia, status epilepticus and hypercapnia

scientific article published on December 1, 1978

Adenosine in Rat Cerebral Cortex: Its Determination, Normal Values, and Correlation to AMP and Cyclic AMP during Shortlasting Ischemia

scientific article published on September 1, 1977

Adenosine in rat cerebral cortex during hypoxia and bicuculline-induced seizures

scientific article published on January 1, 1977

Alfred Benson symposium 3, Copenhagen and Lund May 20-23, 1970

scientific article published on October 15, 1970

Alteration of cyclic adenosine monophosphate response element binding protein in rat brain after hypoglycemic coma.

scientific article published in November 2000

Alterations in lipid and calcium metabolism associated with seizure activity in the postischemic brain

scientific article published on 01 December 2000

Alterations of Akt1 (PKBalpha) and p70(S6K) in transient focal ischemia

scientific article

Amelioration by cyclosporin A of brain damage following 5 or 10 min of ischemia in rats subjected to preischemic hyperglycemia

scientific article

Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat.

scientific article published in November 1998

Anaesthesia and brain metabolism

scientific article

Arachidonic acid metabolism in seizures

scientific article published on January 1989

Are H+ and K+ factors for the adjustment of cerebral blood flow to changes in functional state: a microelectrode study

scientific article published on January 1, 1977

Arterial acid-base changes in unanaesthetized rats in acute hypoxia.

scientific article

Astrocytes fail to regulate intracellular pH at moderately reduced extracellular pH

scientific article published on November 1, 1991

Barbiturates as protective agents in brain ischemia and as free radical scavengers in vitro

scientific article published on January 1980

Basic mechanisms of traumatic brain damage

scientific article

Bicuculline-induced epileptic brain injury. Transient and persistent cell changes in rat cerebral cortex in the early recovery period

scientific article published in January 1983

Bilirubin-Induced Changes in Brain Energy Metabolism after Osmotic Opening of the Blood-Brain Barrier

scientific article published on November 1, 1991

Biochemical basis of tissue acidosis

scientific article published on 01 January 1968

Biochemical events in cerebral ischaemia

scientific article published on July 1, 1975

Biological differences between ischemia, hypoglycemia, and epilepsy

scientific article published on December 1988

Blood Flow and Metabolic Rate for Oxygen in the Cerebral Cortex of the Rat

scientific article published on August 1, 1973

Blood flow and oxygen consumption in the rat brain in dilutional anemia

scientific article published in May 1974

Blood flow and oxygen consumption of the rat brain in profound hypoxia

scientific article published in January 1974

Brain Energy Metabolism in Anesthetized Rats in Acute Anemia

scientific article published on April 1, 1975

Brain Energy Metabolism in Hypoxemia

scientific article published on October 1, 1972

Brain Lactic Acidosis and Ischemic Cell Damage: 1. Biochemistry and Neurophysiology

scientific article published on January 1, 1981

Brain Lactic Acidosis and Ischemic Cell Damage: 2. Histopathology

scientific article published on 01 January 1981

Brain Tryptophan Hydroxylation: Dependence on Arterial Oxygen Tension

scientific article published on October 5, 1973

Brain acidosis in experimental pneumococcal meningitis

scientific article

Brain calcium metabolism in hypoglycemic coma

scientific article published on 01 November 1993

Brain cell death in ischemia and aging: are free radicals involved?

scientific article published on 01 January 1984

Brain cortical fatty acids and phospholipids during and following complete and severe incomplete ischemia

scientific article published in January 1982

Brain dysfunction in cerebral hypoxia and ischemia.

scientific article published in January 1974

Brain energy metabolism and catecholaminergic activity in hypoxia, hypercapnia and ischemia

scientific article published on January 1, 1978

Brain energy metabolism in angiotensin-induced acute hypertension in rats

scientific article published on June 1, 1977

Brain insults in rats induce increased expression of the BDNF gene through differential use of multiple promoters

scientific article

Brain ischemia alters the density of binding sites for glibenclamide, a specific blocker of ATP-sensitive K+ channels

scientific article published in August 1990

Brain metabolism and anaesthesia

scientific article published on January 1, 1978

Brain metabolism and ischemia: mechanism of cell damage and principles of protection.

scientific article published in January 1982

Brain metabolism in the critically ill.

scientific article published on November 1976

Brain tissue carbon dioxide changes and cerebral blood flow measurements

scientific article published in January 1965

Buffer capacity of rat cortical tissue as well as of cultured neurons and astrocytes

scientific article published in August 1993

Calcium accumulation and neuronal damage in the rat hippocampus following cerebral ischemia

scientific article published in February 1987

Calcium and cell death.

scientific article published on January 1989

Calcium and ischemic brain damage

scientific article

Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: a unifying hypothesis

scientific article

Calcium in Ischemic Cell Death

scientific article published on March 1, 1998

Calcium in the brain under physiological and pathological conditions

scientific article published on January 1990

Calcium metabolism of focal and penumbral tissues in rats subjected to transient middle cerebral artery occlusion

scientific article published on June 1, 1998

Calcium, excitotoxins, and neuronal death in the brain

scientific article published on January 1989

Calcium-induced neuronal cell death in vivo and in vitro: are the pathophysiologic mechanisms different?

scientific article published on 01 January 1996

Calcium-mediated processes in neuronal degeneration

scientific article published on December 1994

Calcium-related damage in ischemia

scientific article

Capillary patency after transient middle cerebral artery occlusion of 2 h duration

scientific article published on September 11, 1998

Carbohydrate and amino acid metabolism in rat cerebral cortex in moderate and extreme hypercapnia

scientific article published on October 1, 1975

Cell Damage in the Brain: A Speculative Synthesis

scientific article published on 01 January 1984

Cell damage in the brain: a speculative synthesis

scientific article

Cellular and molecular events underlying epileptic brain damage.

scientific article

Cellular calcium metabolism, seizures, and ischemia

scientific article published in April 1986

Cerebral Blood Flow and Cerebral Energy State

scientific article published on July 1, 1971

Cerebral Blood Flow and Cerebral Metabolic Rate for Oxygen in Rats with Porta-Caval Anastomosis

scientific article published on February 1, 1974

Cerebral Blood Flow and Oxygen Consumption in the Rat Brain during Extreme Hypercarbia

scientific article published on April 1, 1979

Cerebral Blood Flow and Oxygen Consumption in the Rat in Hypoxic Hypoxia

scientific article published on February 1, 1975

Cerebral Blood Flow in Ischemia Caused by Carotid Artery Ligation in the Rat

scientific article published on 01 January 1973

Cerebral Effects of Acute Ammonia Intoxication I. The Influence on Intracellular and Extracellular Acid-Base Parameters

scientific article published on November 1, 1971

Cerebral Energy Metabolism in Hypoxemia

scientific article published on January 1, 1971

Cerebral Energy State and Cerebral Venous Po2in Experimental Hypotension Caused by Bleeding

scientific article published on December 1, 1972

Cerebral Oxygenation in Arterial Hypoxia

scientific article published on January 1, 1976

Cerebral blood flow and cerebral metabolic rate in arterial hypoxia and in immobilization stress

scientific article published on January 1, 1977

Cerebral blood flow and oxygen consumption in normocapnia and hypercapnia: modulating influence of paravertebral sympathetic blockade at the low thoracic level

scientific article published in December 1981

Cerebral blood flow and oxygen consumption in the rat brain after lesions of the noradrenergic locus coeruleus system

scientific article published on 01 March 1981

Cerebral blood flow and oxygen utilization in rats during bicuculline-induced seizures. Effects of substrate depletion

scientific article published on January 1, 1977

Cerebral blood flow during intracranial hypertension related to tissue hypoxia and to acidosis in cerebral extracellular fluids.

scientific article published in January 1968

Cerebral circulation and metabolism

scientific article published on May 1984

Cerebral circulatory responses to hypercapnia and hypoxia in the recovery period following complete and incomplete cerebral ischemia in the rat

scientific article published on 01 July 1983

Cerebral effects of acute ammonia intoxication. II. The effect upon energy metabolism

scientific article published in November 1971

Cerebral energy metabolism in normoxia and in hypoxia

scientific article published on January 1, 1971

Cerebral energy reserves after prolonged hypoxia and ischemia

scientific article published in December 1973

Cerebral energy state in insulin-induced hypoglycemia, related to blood glucose and to EEG.

scientific article

Cerebral extracellular calcium activity in severe hypoglycemia: relation to extracellular potassium and energy state.

scientific article published in June 1984

Cerebral function and energy metabolism at critical thresholds of oxygen availability: a study in rats during status epilepticus induced by bicuculline

scientific article published on January 1, 1977

Cerebral functional, metabolic and circulatory effects of intravenous infusion of adrenaline in the rat

scientific article published on 01 February 1980

Cerebral metabolic and circulatory changes in the rat during sustained seizures induced bydl-homocysteine

scientific article published on December 21, 1979

Cerebral metabolic and circulatory changes induced by hypoxia in starved rats

scientific article published on November 1, 1978

Cerebral metabolic and circulatory effects of 1,1,1-trichloroethane, a neurotoxic industrial solvent. 1. Effects on local cerebral glucose consumption and blood flow during acute exposure.

scientific article published in January 1984

Cerebral metabolic and circulatory effects of 1,1,1-trichloroethane, a neurotoxic industrial solvent. 2. Tissue concentrations of labile phosphates, glycolytic metabolites, citric acid cycle intermediates, amino acids, and cyclic nucleotides

scientific article published on 01 January 1984

Cerebral metabolic changes during and following fluorothyl-induced seizures in ventilated rats

scientific article published in May 1985

Cerebral metabolic changes during prolonged epileptic seizures in rats

scientific article published on May 1, 1977

Cerebral metabolic changes in arterial hypocapnia of short duration

scientific article published in January 1974

Cerebral metabolic changes in profound, insulin-induced hypoglycemia, and in the recovery period following glucose administration

scientific article

Cerebral metabolic rate in hypercarbia--a controversy.

scientific article published on June 1980

Cerebral metabolic state after discontinuation of nitrous oxide supply in artificially ventilated rats

scientific article published in October 1976

Cerebral metabolic state following complete compression ischemia

scientific article published on June 20, 1974

Cerebral metabolism in hypoxic hypoxia. I. Pattern of activation of glycolysis: a re-evaluation

scientific article published on March 14, 1975

Cerebral metabolism in ischaemia: neurochemical basis for therapy

scientific article

Cerebral oxygen consumption and blood flow in hypoxia: influence of sympathoadrenal activation

scientific article published on January 1, 1979

Cerebral oxygen consumption and glucose consumption during status epilepticus

scientific article published on 01 January 1981

Cerebral polyamine metabolism in reversible hypoglycemia of rat: relationship to energy metabolites and calcium

scientific article published in July 1991

Cerebral protein synthesis during long-term recovery from severe hypoglycemia

scientific article published in February 1986

Cerebrospinal fluid lactate-pyruvate ratio in normal and asphyxiated neonates

scientific article published on March 1, 1972

Cerebrovascular response during and following severe insulin-induced hypoglycemia: CO2-sensitivity, autoregulation, and influence of prostaglandin synthesis inhibition

scientific article published on 01 April 1981

Changes in Pyruvate Dehydrogenase Complex Activity during and following Severe Insulin-Induced Hypoglycemia

scientific article published on 01 January 1991

Changes in carbohydrate substrates, amino acids and ammonia in the brain during insulin-induced hypoglycemia

scientific article published in October 1974

Changes in energy state and acid-base parameters of the rat brain during complete compression ischemia

scientific article published on June 20, 1974

Changes in extra- and intracellular pH in the brain during and following ischemia in hyperglycemic and in moderately hypoglycemic rats

scientific article

Changes in ionic fluxes during cerebral ischaemia

scientific article

Changes in labile energy metabolites, redox state and intracellular pH in postischemic brain of normo- and hyperglycemic rats

scientific article published in July 1996

Changes in the bioenergetic state of rat hippocampus during 2.5 min of ischemia, and prevention of cell damage by cyclosporin A in hyperglycemic subjects

scientific article published in March 1997

Changes of labile metabolites during anoxia in moderately hypo- and hyperthermic rats: correlation to membrane fluxes of K+

scientific article published on September 11, 1992

Characteristics of postischemic seizures in hyperglycemic rats

scientific article published in July 1996

Characteristics of the calcium-triggered mitochondrial permeability transition in nonsynaptic brain mitochondria: effect of cyclosporin A and ubiquinone O

scientific article published on 01 May 2000

Chronic dexamethasone pretreatment aggravates ischemic neuronal necrosis

scientific article published in August 1986

Circulating catecholamines modulate ischemic brain damage.

scientific article

Circulatory and metabolic effects in the brain induced by amphetamine sulphate

scientific article published on March 1, 1978

Cortical and cerebrospinal fluid concentrations of reduced and oxidized glutathione during and after cerebral ischemia

scientific article published on January 1, 1979

Coupling among changes in energy metabolism, acid-base homeostasis, and ion fluxes in ischemia

scientific article published on January 1, 1992

Coupling among energy failure, loss of ion homeostasis, and phospholipase A2 and C activation during ischemia

scientific article published on 01 November 1993

Coupling of Cerebral Metabolism and Blood Flow in Epileptic Seizures, Hypoxia and Hypoglycaemia

scientific article published on March 1, 1978

Coupling of cellular energy state and ion homeostasis during recovery following brain ischemia

scientific article published in February 1993

Coupling of energy failure and dissipative K+ flux during ischemia: role of preischemic plasma glucose concentration

scientific article published in March 1993

Critical Oxygen Tensions in the Brain

scientific article published on July 1, 1971

Critical values for plasma glucose in aggravating ischaemic brain damage: correlation to extracellular pH

scientific article published on 01 April 1995

Cyclo-oxygenase inhibition by indomethacin and recirculation following cerebral ischemia

scientific article

Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat.

scientific article

Cyclosporin A enhances survival, ameliorates brain damage, and prevents secondary mitochondrial dysfunction after a 30-minute period of transient cerebral ischemia

scientific article published in September 2000

Cyclosporin A, but not FK506, prevents the downregulation of phosphorylated Akt after transient focal ischemia in the rat.

scientific article published in April 2001

Cytoplasmic and mitochondrial redox changes in the brain during hypoxia

scientific article published on January 1, 1979

Decrease of glutamate decarboxylase activity in substantia nigra and caudoputamen following transient hyperglycemic ischemia in the rat

scientific article published on 01 December 1989

Delayed hypoperfusion in the cerebral cortex of the rat in the recovery period following severe hypoglycemia

scientific article published on 01 July 1979

Delayed treatment with alpha-phenyl-N-tert-butyl nitrone (PBN) attenuates secondary mitochondrial dysfunction after transient focal cerebral ischemia in the rat.

scientific article published in April 1996

Delayed treatment with the spin trap alpha-phenyl-N-tert-butyl nitrone (PBN) reduces infarct size following transient middle cerebral artery occlusion in rats

scientific article published in November 1994

Differential neuroprotection by cyclosporin A and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition

scientific article published in August 2002

Differential phosphorylation at Ser473 and Thr308 of Akt-1 in rat brain following hypoglycemic coma

scientific article published on 01 September 2000

Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma

scientific article published on January 1992

Does ischemia with reperfusion lead to oxidative damage to proteins in the brain?

scientific article published in January 1993

Does long-term glucose infusion reduce brain damage after transient cerebral ischemia?

scientific article

Early axonal lesion and preserved microvasculature in epilepsy-induced hypermetabolic necrosis of the substantia nigra

scientific article published in January 1986

Early release of cytochrome C and activation of caspase-3 in hyperglycemic rats subjected to transient forebrain ischemia

scientific article published in March 2001

Editorial: Metabolic control of intracellular pH.

scientific article published on October 1973

Effect of Hypercapnia and Hypocapnia on Tryptophan and Tyrosine Hydroxylation in Rat Brain

scientific article published on April 1, 1977

Effect of Ischemia on Monoamine Metabolism in the Brain

scientific article published on April 1, 1974

Effect of NXY-059 on secondary mitochondrial dysfunction after transient focal ischemia; comparison with cyclosporin A.

scientific article published in April 2002

Effect of alpha-phenyl-N-tert-butyl nitrone (PBN) on fetal cerebral energy metabolism during intrauterine ischemia and reperfusion in rats

scientific article published on 01 April 2000

Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat.

scientific article published in May 1982

Effect of hypothermia upon organic phosphates, glycolytic metabolites, citric acid cycle intermediates and associated amino acids in rat cerebral cortex

scientific article published on April 1, 1975

Effect of hypoxia on blood flow and metabolic flux in the brain

scientific article published on January 1, 1979

Effect of indomethacin on local cerebral blood flow in awake, minimally restrained rats.

scientific article published in January 1981

Effect of nitrous oxide on local cerebral glucose utilization in rats

scientific article

Effect of propranolol on local cerebral blood flow under normocapnic and hypercapnic conditions

scientific article published on 01 January 1981

Effect of the calcium antagonist nimodipine on the delayed hypoperfusion following incomplete ischemia in the rat

scientific article published on 01 December 1983

Effect of transient focal ischemia on blood-brain barrier permeability in the rat: correlation to cell injury

scientific article published on August 1, 1997

Effects of Hypoxia of 10-45 Seconds Duration on Energy Metabolism in the Cerebral Cortex of Unanesthetized and Anesthetized Rats

scientific article published on November 1, 1975

Effects of Increased Intracranial Pressure on Cerebral Blood Flow and on Cerebral Venous pO2, pCO2, pH, Lactate and Pyruvate in Dogs

scientific article published in March 1969

Effects of Indomethacin on Cerebral Blood Flow and Oxygen Consumption in Barbiturate-Anesthetized Normocapnic and Hypercapnic Rats

scientific article published on January 1, 1981

Effects of Streptozotocin-Induced Hyperglycemia on Brain Damage Following Transient Ischemia

scientific article published on August 1, 1998

Effects of bicuculline-induced seizures on cerebral metabolism and circulation of rats rendered hypoglycemic by starvation

scientific article published on February 1, 1979

Effects of cyclosporin A administration on gene expression in rat brain

article

Effects of dimethylthiourea on ischemic brain damage in hyperglycemic rats

scientific article published on December 1, 1992

Effects of dimethylthiourea on selective neuronal vulnerability in forebrain ischemia in rats

scientific article

Effects of hyperglycemia and hypercapnia on lipid metabolism during complete brain ischemia

scientific article published in December 2004

Effects of increased cerebrospinal fluid pressure upon adenine nucleotides and upon lactate and pyruvate in rat brain tissue

scientific article published in January 1970

Effects of increased intracranial pressure on cerebral blood flow and on cerebrospinal fluid HCO3, pH, lactate and pyruvate in dogs

scientific article published in March 1969

Effects of insulin-induced hypoglycemia on intracellular pH and impedance in the cerebral cortex of the rat.

scientific article published in September 1981

Effects of intracarotid arterial injection of cyclosporin A and spontaneous hypothermia on brain damage incurred after a long period of global ischemia

scientific article

Effects of phenobarbital anaesthesia on postischemic cerebral blood flow and oxygen consumption in the rat

scientific article published on January 1, 1977

Effects of phenobarbital in cerebral ischemia. Part I: cerebral energy metabolism during pronounced incomplete ischemia

scientific article published on July 1, 1978

Effects of phenobarbital in cerebral ischemia. Part II: restitution of cerebral energy state, as well as of glycolytic metabolites, citric acid cycle intermediates and associated amino acids after pronounced incomplete ischemia

scientific article

Effects of the spin trap-alpha-phenyl-N-tert-butyl nitrone (PBN) in transient forebrain ischaemia in the rat

scientific article published on 01 May 1996

Effects on cerebral energy state of arterial hypotension in rats with porta-caval anastomosis

scientific article published in February 1974

Electrolyte shifts between brain and plasma in hypoglycemic coma

scientific article

Elimination of autoregulation following a period of pronounced intracranial hypertension: is hypoxia involved?

scientific article published in January 1968

Endogenous Substrates Utilized by Rat Brain in Severe Insulin-Induced Hypoglycemia

scientific article published on 01 February 1981

Energy Metabolism and Histology in the Brain during Combined Hypoxemia and Ischemia

scientific article published on January 1, 1971

Energy flux and lactate production in rat cerebral cortex during the first 5-10 s of bicuculline-induced seizures

scientific article published on December 1, 1978

Energy metabolism, ion homeostasis, and cell damage in the brain

scientific article published on November 1, 1994

Enhancement of iron-catalyzed free radical formation by acidosis in brain homogenates: differences in effect by lactic acid and CO2

scientific article published on 01 February 1989

Epileptic brain damage: pathophysiology and neurochemical pathology

scientific article

Epileptic brain damage: the role of systemic factors that modify cerebral energy metabolism

scientific article

Evidence Against H+and K+as main Factors for the Control of Cerebral Blood Flow: A Microelectrode Study

scientific article published on March 1, 1978

Evidence against major compartmentalization of H+ in ischemic rat brain tissue

scientific article

Evidence of Cerebral Hypoxia in Pronounced Hyperventilation

scientific article published in January 1968

Excessive cellular acidosis: an important mechanism of neuronal damage in the brain?

scientific article published on 01 December 1980

Excessive increase in oxygen uptake and blood flow in the brain during amphetamine intoxication

scientific article published in June 1976

Extra- and Intracellular pH in the Brain During Ischaemia, Related to Tissue Lactate Content in Normo- and Hypercapnic rats

scientific article published in January 1992

Extra- and intracellular pH during near-complete forebrain ischemia in the rat.

scientific article published in February 1986

Extra- and intracellular pH in the brain during seizures and in the recovery period following the arrest of seizure activity

scientific article

Extra-and intracellular acid-base relations in the brain.

scientific article published in January 1968

Extracellular pH in the Brain and Cerebral Blood Flow

scientific article

Extracellular pH in the brain during ischemia: relationship to the severity of lactic acidosis

scientific article published in July 1991

Extracellular pH in the rat brain during hypoglycemic coma and recovery

scientific article published in March 1990

Extracellular potassium in a neocortical core area after transient focal ischemia

scientific article published in January 1997

Factors affecting H+ and HCO3- in the cerebrospinal fluid

scientific article published in January 1968

Factors affecting the cerebrospinal fluid (CSF) bicarbonate concentration

scientific article published on 01 September 1966

Focal and Perifocal Changes in Tissue Energy State during Middle Cerebral Artery Occlusion in Normo- and Hyperglycemic Rats

scientific article published on January 1, 1992

Free Fatty Acids in the Rat Brain in Moderate and Severe Hypoxia

scientific article published on April 1, 1981

Free fatty acids in the brain in bicuculline-induced status epilepticus

scientific article published on 01 November 1980

Free radical production and ischemic brain damage: influence of postischemic oxygen tension

scientific article

Free radicals and brain damage due to transient middle cerebral artery occlusion: the effect of dimethylthiourea

scientific article published on January 1, 1993

Free radicals and brain damage.

scientific article published on January 1989

Frontal cortex lesion prior to hyperglycemic ischemia: no decrease in ensuing substantia nigra pars reticulata damage or fatal post-ischemic seizures

scientific article published on January 1, 1992

Functional, metabolic, and circulatory changes associated with seizure activity in the postischemic brain

scientific article

Glucose Consumption in Rat Cerebral Cortex in Normoxia, Hypoxia and Hypercapnia

scientific article published on April 1, 1976

Glucose consumption in the cerebral cortex of rat during bicuculline-induced status epilipticus

scientific article published in October 1976

Glutamate, calcium, and free radicals as mediators of ischemic brain damage

scientific article published on 01 May 1995

Glycogen accumulated in the brain following insults is not degraded during a subsequent period of ischemia

scientific article published in April 1996

Graded hypoxia-oligemia in rat brain. I. Biochemical alterations and their implications

scientific article published in October 1973

Gradients of CO2 tension in the brain

scientific article published in June 1966

Histopathological changes in the rat brain during bicuculline-induced status epilepticus.

scientific article published in January 1983

Historical overview. Calcium, ischemia, and death of brain cells

scientific article published on January 1988

Homeostatic regulation of brain energy metabolism in hypoxia

scientific article published in June 1973

Hyperglycemia and Hypercapnia Suppress BDNF Gene Expression in Vulnerable Regions after Transient Forebrain Ischemia in the Rat

scientific article published on December 1, 1997

Hyperglycemia and focal brain ischemia

scientific article published in March 1999

Hyperglycemia and hypercapnia differently affect post-ischemic changes in protein kinases and protein phosphorylation in the rat cingulate cortex

scientific article published in January 2004

Hyperglycemia enhances DNA fragmentation after transient cerebral ischemia

scientific article published in May 2001

Hyperglycemia enhances extracellular glutamate accumulation in rats subjected to forebrain ischemia

scientific article published on 01 January 2000

Hyperglycemia-exaggerated ischemic brain damage following 30 min of middle cerebral artery occlusion is not due to capillary obstruction

scientific article published on August 31, 1998

Hyperthermia aggravates and hypothermia ameliorates epileptic brain damage

scientific article published on January 1994

Hyperthermia complicates middle cerebral artery occlusion induced by an intraluminal filament

scientific article published on June 1994

Hyperthermia nullifies the ameliorating effect of dizocilpine maleate (MK-801) in focal cerebral ischemia

scientific article published on January 1995

Hypoglycaemia: brain neurochemistry and neuropathology.

scientific article

Hypoglycemia, brain metabolism, and brain damage.

scientific article published on March 1988

Hypoglycemia-Elicited Immediate Early Gene Expression in Neurons and Glia of the Hippocampus: Novel Patterns of FOS, JUN, and KROX Expression following Excitotoxic Injury

scientific article published on November 1, 1995

Hypoglycemic Brain Injury: Phospholipids, Free Fatty Acids, and Cyclic Nucleotides in the Cerebellum of the Rat after 30 and 60 Minutes of Severe Insulin-Induced Hypoglycemia

scientific article published on 01 January 1981

Hypoglycemic brain injury in the rat. Correlation of density of brain damage with the EEG isoelectric time: a quantitative study

scientific article published in November 1984

Hypoglycemic brain injury. I. Metabolic and light microscopic findings in rat cerebral cortex during profound insulin-induced hypoglycemia and in the recovery period following glucose administration

scientific article published on 01 January 1980

Hypoglycemic brain injury. II. Electron-microscopic findings in rat cerebral cortical neurons during profound insulin-induced hypoglycemia and in the recovery period following glucose administration

scientific article published on 01 January 1980

Hypoglycemic brain injury: metabolic and structural findings in rat cerebellar cortex during profound insulin-induced hypoglycemia and in the recovery period following glucose administration

scientific article published on 01 January 1981

Hypotension as a complication of hypoglycemia leads to enhanced energy failure but no increase in neuronal necrosis

scientific article published on May 1986

Hypothermia ameliorates ischemic brain damage and suppresses the release of extracellular amino acids in both normo- and hyperglycemic subjects

scientific article published in July 1999

Increase in Cerebral Oxygen Uptake and Blood Flow in Immobilization Stress

scientific article published on October 1, 1975

Increase in local cerebral blood flow induced by circulating adrenaline: involvement of blood-brain barrier dysfunction

scientific article published on November 1, 1979

Increased production of the TrkB protein tyrosine kinase receptor after brain insults

scientific article published in February 1993

Induced spreading depressions in energy-compromised neocortical tissue: calcium transients and histopathological correlates

scientific article published on 01 November 1994

Influence of Amphetamine Sulphate on Cerebral Blood Flow and Metabolism

scientific article published on May 1, 1975

Influence of Changes in Arterial PCO2on Cerebral Blood Flow and Cerebral Energy State during Hypothermia in the Rat

scientific article published on January 1, 1975

Influence of Phenobarbital Anesthesia on Carbohydrate and Amino Acid Metabolism in Rat Brain

scientific article published on March 1, 1978

Influence of acid-base changes on the intracellular calcium concentration of neurons in primary culture

scientific article published on January 1994

Influence of acidosis on lipid peroxidation in brain tissues in vitro.

scientific article published in June 1985

Influence of anaesthetics on the balance between production and utilization of energy in the brain

scientific article

Influence of blood glucose concentration on brain lactate accumulation during severe hypoxia and subsequent recovery of brain energy metabolism

scientific article

Influence of complete and pronounced incomplete cerebral ischemia and subsequent recirculation on cortical concentrations of oxidized and reduced glutathione in the rat

scientific article published on 01 March 1980

Influence of complete ischemia on glycolytic metabolites, citric acid cycle intermediates, and associated amino acids in the rat cerebral cortex

scientific article published in November 1974

Influence of hyperglycemia and of hypercapnia on cellular calcium transients during reversible brain ischemia

scientific article published on 01 January 1995

Influence of hypoglycemic coma on brain water and osmolality

scientific article published on June 1, 1998

Influence of hypoxia on cerebral energy state in rats with porta-caval anastomosis

scientific article

Influence of in vitro lactic acidosis and hypercapnia on respiratory activity of isolated rat brain mitochondria

scientific article published in September 1984

Influence of intravenously administered catecholamines on cerebral oxygen consumption and blood flow in the rat.

scientific article

Influence of ischemia on blood-brain and blood-CSF calcium transport

scientific article published on May 1, 1992

Influence of lesions of the noradrenergic locus coeruleus system on the cerebral metabolic response to bicuculline-induced seizures

scientific article published on 01 April 1983

Influence of moderate hypothermia on ischemic brain damage incurred under hyperglycemic conditions

scientific article published on 01 January 1991

Influence of nitrous oxide on local cerebral blood flow in awake, minimally restrained rats.

scientific article published in January 1981

Influence of phenobarbital on changes in the metabolites of the energy reserve of the cerebral cortex following complete ischemia

scientific article

Influence of plasma glucose concentration on rat brain extracellular calcium transients during spreading depression

scientific article published in January 1993

Influence of preischemic hyperglycemia on osmolality and early postischemic edema in the rat brain

scientific article published on September 1, 1992

Influence of propranolol on cerebral metabolism and blood flow in the rat brain

scientific article published on July 28, 1978

Influence of reduced oxygen availability on cerebral metabolic changes during bicuculline-induced seizures in rats

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Influence of severe hypoglycemia on brain extracellular calcium and potassium activities, energy, and phospholipid metabolism.

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Influence of severe hypoglycemia on mitochondrial and plasma membrane function in rat brain

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Influence of systemic factors on experimental epileptic brain injury. Structural changes accompanying bicuculline-induced seizures in rats following manipulations of tissue oxygenation or alpha-tocopherol levels

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Influence of tissue acidosis upon restitution of brain energy metabolism following total ischemia

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Intracellular pH in the brain following transient ischemia

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Intracellular pH of the brain in arterial hypoxemia, evaluated with the CO 2 method and from the creatine phosphokinase equilibrium

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Intracellular pH regulation in cultured rat astrocytes in CO2/HCO3(-)-containing media

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Ischemic brain damage: focus on lipids and lipid mediators

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Ischemic penumbra in a model of reversible middle cerebral artery occlusion in the rat

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Labile metabolites and phosphorylase a in rapidly frozen rat cerebral cortex

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Lactate and pyruvate levels in blood, cerebrospinal fluid and brain tissue.

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Lactic Acidosis in the Brain: Occurrence, Triggering Mechanisms and Pathophysiological Importance

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Lactic acidosis and recovery of mitochondrial function following forebrain ischemia in the rat.

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Local cerebral blood flow in the recovery period following complete cerebral ischemia in the rat.

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Metabolic state and blood flow in rat cerebral cortex, cerebellum and brainstem in hypoxic hypoxia

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Metabolism and Flow in the Hypoxic Brain

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NXY-059, a nitrone with free radical trapping properties inhibits release of cytochrome c after focal cerebral ischemia.

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Prostaglandins and the cerebral circulation.

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Proton microprobe and particle induced X-ray emission (PIXE) analysis for studies of pathological brain tissue.

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Rate of Energy Utilization in the Cerebral Cortex of Rats

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Recent Advances in CSF Physiology

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Recirculation in the rat brain following incomplete ischemia

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Regional Cerebral Blood Flow during and after 2 Hours of Middle Cerebral Artery Occlusion in the Rat

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Regional brain-derived neurotrophic factor mRNA and protein levels following transient forebrain ischemia in the rat.

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Regional cerebral blood flow in the rat measured by the tissue sampling technique; a critical evaluation using four indicators C14-antipyrine, C14-ethanol H3-water and xenon

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Regional differences in brain glucose content in graded hypoglycemia

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Regional differences in vascular autoregulation in the rat brain in severe insulin-induced hypoglycemia

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Regulation of CSF pH - Influence of the CSF/Plasma Potential

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Regulation of Intracellular pH in the Rat Brain in Chronic Hypercapnia

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Regulation of brain-derived neurotrophic factor gene expression after transient middle cerebral artery occlusion with and without brain damage

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Regulation of extra- and intracellular pH in the brain in severe hypoglycemia

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Regulation of lactate and pyruvate levels in the CSF.

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Regulation of microcirculation in the brain

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Regulation of the CSF pH in Acute and Sustained Respiratory Acidosis

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Regulatory mechanisms affecting carbohydrate substrates in the brain in hypercapnic acidosis

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Relationship between intra- and extracellular pH in primary cultures of rat astrocytes

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Reply to the remarks by J. B. Brierley and A. W. Brown

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Restitution of cerebral energy state, as well as of glycolytic metabolites, citric acid cycle intermediates and associated amino acids after 30 minutes of complete ischemia in rats anaesthetized with nitrous oxide or phenobarbital

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Restoration of oxygen uptake and blood flow in the rat cerebral cortex after halothane anaesthesia

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Reversible ischemia of the brain: biochemical factors influencing restitution

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Role and mechanisms of secondary mitochondrial failure.

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Role of hyperglycaemia‐related acidosis in ischaemic brain damage

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Secondary bioenergetic failure after transient focal ischaemia is due to mitochondrial injury

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Seizure-induced damage to substantia nigra and globus pallidus is accompanied by pronounced intra- and extracellular acidosis

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Selective lesions of mesostriatal dopamine neurons ameliorate hypoglycemic damage in the caudate-putamen

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Severe hypoglycemia leads to accumulation of arachidonic acid in brain tissue

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Signs of cerebral hypoxia in hyperventilation

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Signs of tissue hypoxia in infantile hydrocephalus

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Status epilepticus in well-oxygenated rats causes neuronal necrosis

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Substantia nigra damage induced by ischemia in hyperglycemic rats. A light and electron microscopic study

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Survival- and death-promoting events after transient cerebral ischemia: phosphorylation of Akt, release of cytochrome C and Activation of caspase-like proteases

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Sustained epileptic seizures complicated by hypoxia, arterial hypotension or hyperthermia: effects on celebral energy state

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Symposium on acid-base homeostasis. The regulation of cerebrospinal fluid pH.

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The CSF lactate/pyruvate ratio in cerebral hypoxia

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The CSF/Blood Potential in Sustained Acidosis and Alkalosis in the Rat

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The DC Potential between CSF and Plasma in Respiratory Acidosis

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The Effect of Acute and Chronic Hypercapnia upon the Lactate, Pyruvate, α‐ketoglutarate, Glutamate and Phosphocreatine Contents of the Rat Brain

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The Effect of Anesthetics on the Tissue Lactate, Pyruvate, Phosphocreatine, ATP and AMP Concentrations, and on Intracellular pH‘ in the Rat Brain

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The Effect of Anesthetics upon Labile Phosphates and upon Extra- and Intracellular Lactate, Pyruvate and Bicarbonate Concentrations in the Rat Brain

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The Effect of Arterial Hypoxemia upon Acid‐Base Parameters in Arterial Blood and Cisternal Gerebrospinal Fluid of the Rat

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The Effect of Asphyxia upon the Lactate, Pyruvate and Bicarbonate Concentrations of Brain Tissue and Cisternal CSF, and upon the Tissue Concentrations of Phosphocreatine and Adenine Nucleotides in Anesthetized Rats

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The Effect of Bilateral Carotid Artery Ligation upon Acid-Base Parameters and Substrate Levels in the Rat Brain

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The Effect of Deep Halothane Hypotension upon Labile Phosphates and upon Extra‐ and Intracellular Lactate and Pyruvate Concentrations in the Rat Brain

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The Effect of Halothane Anaesthesia upon Cerebral Oxygen Consumption in the Rat

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The Effect of Hypercapnia upon the Energy Metabolism of the Brain during Arterial Hypoxemia

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The Effect of Hypovolemic Hypotension on Extra- and Intracellular Acid-Base Parameters and Energy Metabolites in the Rat Brain

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The Effect of Ischemia upon the Energy State of the Brain

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The Effect of Nitrous Oxide on Oxygen Consumption and Blood Flow in the Cerebral Cortex of the Rat

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The Effect of Pronounced Hypoglycemia on Monoamine Metabolism in Rat Brain

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The Effects of Hypercapnia and Hypocapnia upon the Cerebrospinal Fluid Lactate and Pyruvate Concentrations and upon the Lactate, Pyruvate, ATP, ADP, Phosphocreatine and Creatine Concentrations of Cat Brain Tissue

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The Immunosuppressant Drug FK506 Ameliorates Secondary Mitochondrial Dysfunction Following Transient Focal Cerebral Ischemia in the Rat

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The In Vivo CO2Buffer Capacity of Rat Brain Tissue under Carbonic Anhydrase Inhibition

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The Influence of Acute Normovolemic Anemia on Cerebral Blood Flow and Oxygen Consumption of Anesthetized Rats

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The Influence of Arterial Hypoxemia upon Labile Phosphates and upon Extracellular and Intracellular Lactate and Pyruvate Concentrations in the Rat Brain

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The Influence of Hypoxia on the Concentrations of Cyclic Nucleotides in the Rat Brain

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The Intracellular pH‘ in the Brain in Acute and Sustained Hypercapnia

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The Lactate/Pyruvate Ratios of Cerebrospinal Fluid of Rats and Cats Related to the Lactate/Pyruvate, the ATP/ADP, and the Phosphocreatine/Creatine Ratios of Brain Tissue

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The Regulation of Extra- and Intracellular Acid-Base Parameters in the Rat Brain during Hyper- and Hypocapnia

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The Relationship between Arterial PO2and Cerebral Blood Flow in Hypoxic Hypoxia

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The bicarbonate/carbonic acid buffer system of the cerebral cortex of cats, as studied in tissue homogenates. 1. The amount of carbon dioxide bound at different carbon dioxide tensions. With a critique of the application of chloride space measuremen

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The biochemical basis of cerebral ischemic damage

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The biochemical basis of ischemic brain lesions

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The brain in extreme respiratory acidosis. A light- and electron-microscopic study in the rat.

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The buffer capacity of brain tissue and of equivalent systems

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The calmodulin antagonist trifluoperazine in transient focal brain ischemia in rats. Anti-ischemic effect and therapeutic window

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The density and distribution of ischemic brain injury in the rat following 2?10 min of forebrain ischemia

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The distribution of hypoglycemic brain damage

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The effect of a dihydropyridine calcium antagonist (isradipine) on selective neuronal necrosis

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The effect of acetazolamide upon tissue concentrations of bicarbonate, lactate, and pyruvate in the rat brain

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The effect of alpha-phenyl-N-tert-butyl nitrone on bioenergetic state in substantia nigra following flurothyl-induced status epilepticus in rats

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The effect of ammonia on the energy metabolism of the rat brain

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The effect of arterial hypotension upon the lactate, pyruvate and bicarbonate concentrations of brain tissue and cisternal CSF, and upon the tissue concentrations of phosphocreatine and adenine nucleotides in anesthetized rats

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The effect of bilateral carotid artery ligation upon the blood flow and the energy state of the rat brain

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The effect of combined respiratory and nonrespiratory alkalosis on energy metabolites and acid-base parameters in the rat brain

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The effect of hypercapnia upon intracellular pH in the brain, evaluated by the bicarbonate-carbonic acid method and from the creatine phosphokinase equilibrium

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The effect of hypercapnic acidosis upon some glycolytic and Krebs cycle-associated intermediates in the rat brain

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The effect of hypercapnic acidosis upon the energy metabolism of the brain in arterial hypotension caused by bleeding

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The effect of hyperthermia upon oxygen consumption and upon organic phosphates, glycolytic metabolites, citric and cycle intermediates and associated amino acids in rat cerebral cortes

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The effect of indomethacin on cerebral blood flow and oxygen consumption in the rat at normal and increased carbon dioxide tensions

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The effect of indomethacin on the blood flow-metabolism couple in the brain under normal, hypercapnic and hypoxic conditions

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The effect of induced hypothermia upon oxygen consumption in the rat brain

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The effect of marked hyperventilation upon tissue levels of NADH, lactate, pyruvate, phosphocreatine, and adenosine phosphates of rat brain

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The effect of mild hyperthermia and hypothermia on brain damage following 5, 10, and 15 minutes of forebrain ischemia

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The effect of moderate and marked hypercapnia upon the energy state and upon the cytoplasmic NADH-NAD+ ratio of the rat brain

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The effect of phenobarbitone anaesthesia on blood flow and oxygen consumption in the rat brain

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The effect of phenobarbitone anaesthesia upon some organic phosphates, glycolytic metabolites and citric acid cycle-associated intermediates of the rat brain

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The effect of porta-caval anastomosis upon the energy state and upon acid-base parameters of the rat brain

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The effects of diazepam on cerebral blood flow and oxygen consumption in rats and its synergistic interaction with nitrous oxide

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The immunosuppressants cyclosporin A and FK506 equally ameliorate brain damage due to 30-min middle cerebral artery occlusion in hyperglycemic rats

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The increase in extracellular potassium concentration in the ischemic brain in relation to the preischemic functional activity and cerebral metabolic rate

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The influence of acidosis on hypoglycemic brain damage

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The influence of arterial hypoxia and unilateral carotid artery occlusion upon regional blood flow and metabolism in the rat brain

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The influence of bicuculline-induced seizures on free fatty acid concentrations in cerebral cortex, hippocampus, and cerebellum.

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The influence of calcium transients on intracellular pH in cortical neurons in primary culture

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The influence of circulating adrenaline on extracellular fluid potassium concentration in the brain

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The influence of deep barbiturate anesthesia upon the regulation of extra- and intracellular pH in the rat brain during hypercapnia

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The influence of hypocapnia upon intracellular pH and upon some carbohydrate substrates, amino acids and organic phosphates in the brain

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The influence of hypothermia on hypoglycemia-induced brain damage in the rat

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The influence of insulin-induced hypoglycemia on the calcium transients accompanying reversible forebrain ischemia in the rat

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The influence of mild body and brain hypothermia on ischemic brain damage

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The influence of moderate hypothermia on cellular calcium uptake in complete ischaemia: implications for the excitotoxic hypothesis

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The influence of nitrous oxide and barbiturate anaesthesia upon the energy and the acid-base metabolism of the brain in normoxia and hypoxia

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The influence of pH on cellular calcium influx during ischemia

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The influence of pH on glutamate- and depolarization-induced increases of intracellular calcium concentration in cortical neurons in primary culture

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The influence of plasma glucose concentrations on ischemic brain damage is a threshold function

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The influence of repeated spreading depression-induced calcium transients on neuronal viability in moderately hypoglycemic rats

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The influence of respiratory disturbances on acid-base and energy metabolism of the brain

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The ionic basis of neurocytotoxic damage

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The metabolism of purine and pyrimidine nucleotides in rat cortex during insulin-induced hypoglycemia and recovery

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The omega-conopeptide SNX-111, an N-type calcium channel blocker, dramatically ameliorates brain damage due to transient focal ischaemia

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The rate of incorporation of gaseous14CO2 into brain tissue constituents

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The regulation of intracellular pH in cultured astrocytes and neuroblastoma cells, and its dependence on extracellular pH in a HCO3-free solution

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The regulation of intracellular pH is strongly dependent on extracellular pH in cultured rat astrocytes and neurons

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The relation between the bicarbonate concentration in blood plasma and in brain tissue

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The temporal evolution of hypoglycemic brain damage. II. Light- and electron-microscopic findings in the hippocampal gyrus and subiculum of the rat.

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The temporal evolution of hypoglycemic brain damage. III. Light and electron microscopic findings in the rat caudoputamen

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Thresholds in cerebral ischemia - the ischemic penumbra

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Time course of early brain edema following reversible forebrain ischemia in rats

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Tissue NADH levels in the rat brain during pronounced hyperventilation

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Tissue PCO2 in brain ischemia related to lactate content in normo- and hypercapnic rats

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Tissue lactate content and tissuePCO2in complete brain ischaemia: implications for compartmentation of H+

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Transient ischemia leads to intracellular alkalosis in the brain

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Variation of extracellular fluid pH: effect on CBF.

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[Future treatment of stroke. Brain damage in stroke can be reduced by drugs]

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[Future treatment of stroke. Brain injury can be reduced with drugs]

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[Mechanisms of brain cell damage in hypoxia and ischemia]

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[Theoretical and practical aspects of liver coma]

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