List of works - Charlotte Manisty

'Splenic switch-off' to detect adenosine understress; a novel method to improve test sensitivity.

scientific article

A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study

scientific article published in 2022

A novel fully automated method for mitral regurgitant orifice area quantification

scientific article published on 2 January 2012

Abnormal septal convexity into the left ventricle occurs in subclinical hypertrophic cardiomyopathy ⬇️

scientific article published on 30 July 2015

Applicability of the iterative technique for cardiac resynchronization therapy optimization: full-disclosure, 50-sequential-patient dataset of transmitral Doppler traces, with implications for future research design and guidelines

scientific article published on 25 September 2013

Assessing for Cardiotoxicity from Metal-on-Metal Hip Implants with Advanced Multimodality Imaging Techniques.

scientific article published in November 2017

Atorvastatin treatment is associated with less augmentation of the carotid pressure waveform in hypertension: a substudy of the Anglo-Scandinavian Cardiac Outcome Trial (ASCOT).

scientific article published on 31 August 2009

Attenuation of wave reflection by wave entrapment creates a "horizon effect" in the human aorta

scientific article

Automated Extracellular Volume Fraction Mapping Provides Insights Into the Pathophysiology of Left Ventricular Remodeling Post-Reperfused ST-Elevation Myocardial Infarction

scientific article published on 11 July 2016

Automated speckle tracking algorithm to aid on-axis imaging in echocardiography

scientific article published on October 2014

Automatic Measurement of the Myocardial Interstitium: Synthetic Extracellular Volume Quantification Without Hematocrit Sampling

scientific article published on January 2016

Automatic left ventricular analysis with Inline VF performs well compared to manual analysis: results from Barts Cardiovascular Registry.

scientific article published on 27 January 2016

CMR myocardial texture analysis tracks different etiologies of left ventricular hypertrophy.

scientific article published on 27 January 2016

Can left ventricular endocardial surface roughness be measured by fractal dimension on fast gradient echo sequences?

scientific article published on 27 January 2016

Cardiac MRI evaluation of myocardial disease

scientific article published on 27 June 2016

Choosing between velocity-time-integral ratio and peak velocity ratio for calculation of the dimensionless index (or aortic valve area) in serial follow-up of aortic stenosis

scientific article

Chronic iron deposit and left ventricular remodeling in reperfused STEMI patients

scientific article published on 27 January 2016

Clinical application of MOLLI T1* for extracellular volume calculation in healthy volunteers and aortic stenosis

scientific article published on 3 February 2015

Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study

Current provision for MRI scanning of patients with cardiac implantable electronic devices - a national survey of hospitals in England.

scientific article published on 27 January 2016

Defining left ventricular remodeling following acute ST-segment elevation myocardial infarction using cardiovascular magnetic resonance

scientific article published on 13 March 2017

Definitions of Outcome, Response and Effect in Imaging Research to Avoid Confusion

scientific article published on 01 January 2014

Detection of metallic cobalt and chromium liver deposition following failed hip replacement using T2* and R2 magnetic resonance

scientific article published on 6 May 2016

Development of respiratory control instability in heart failure: a novel approach to dissect the pathophysiological mechanisms

scientific article

Diagnosis and Prognosis in Sudden Cardiac Arrest Survivors Without Coronary Artery Disease: Utility of a Clinical Approach Using Cardiac Magnetic Resonance Imaging.

scientific article published in December 2017

Diagnostic performance of T1 and T2 mapping to detect intramyocardial hemorrhage in reperfused ST-segment elevation myocardial infarction (STEMI) patients

scientific article published on 15 February 2017

Differences in the magnitude of wave reflection account for differential effects of amlodipine- versus atenolol-based regimens on central blood pressure: an Anglo-Scandinavian Cardiac Outcome Trial substudy

scientific article published on 24 August 2009

Diffuse myocardial fibrosis - a therapeutic target? Proof of regression at 1-year following aortic valve replacement: the RELIEF-AS study.

scientific article

Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection

scientific article published on 01 December 2020

Doctors should not discuss resuscitation with terminally ill patients: FOR.

scientific article

Dynamic CO2 therapy in periodic breathing: a modeling study to determine optimal timing and dosage regimes

scientific article published on 23 July 2009

ECG, LVH and T1 changes in Fabry disease - implications for screening and understanding of the disease model.

scientific article published on 27 January 2016

Effect of study design on the reported effect of cardiac resynchronization therapy (CRT) on quantitative physiological measures: stratified meta-analysis in narrow-QRS heart failure and implications for planning future studies

scientific article

Efficiency, reproducibility and agreement of five different hemodynamic measures for optimization of cardiac resynchronization therapy

scientific article published on 18 September 2007

Ejection fraction: a measure of desperation?

scientific article published on 01 April 2008

Evaluation of splenic switch off in a tertiary imaging centre: validation and assessment of utility

scientific article published on 06 October 2016

Evidence of a dominant backward-propagating "suction" wave responsible for diastolic coronary filling in humans, attenuated in left ventricular hypertrophy

scientific article published on 3 April 2006

Evidence that conflict regarding size of haemodynamic response to interventricular delay optimization of cardiac resynchronization therapy may arise from differences in how atrioventricular delay is kept constant

scientific article

Evidence-based recommendations for PISA measurements in mitral regurgitation: systematic review, clinical and in-vitro study

scientific article

First-in-man safety evaluation of renal denervation for chronic systolic heart failure: primary outcome from REACH-Pilot study

scientific article published on 29 September 2012

Graft-versus-host disease: a case report of a rare but reversible cause of constrictive pericarditis

scientific article published on 04 March 2020

Guidance for accurate and consistent tissue Doppler velocity measurement: comparison of echocardiographic methods using a simple vendor-independent method for local validation

scientific article

Haemodynamic effects of changes in atrioventricular and interventricular delay in cardiac resynchronisation therapy show a consistent pattern: analysis of shape, magnitude and relative importance of atrioventricular and interventricular delay

scientific article published on 18 May 2006

Hematocrit, iron and HDL-cholesterol explain 90% of variation in native blood T1.

scientific article published on 27 January 2016

Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure

scientific article published on 14 June 2022

Impact of microvascular obstruction on semiautomated techniques for quantifying acute and chronic myocardial infarction by cardiovascular magnetic resonance.

scientific article published on 12 December 2016

Improved Exercise-Related Skeletal Muscle Oxygen Consumption Following Uptake of Endurance Training Measured Using Near-Infrared Spectroscopy

scientific article published on 12 December 2017

Incidence of left ventricular thrombi in reperfused STEMI patients detected by contrast-enhanced CMR.

scientific article published on 3 February 2015

Induction of oscillatory ventilation pattern using dynamic modulation of heart rate through a pacemaker

scientific article published on 7 May 2008

Insight into hypertrophied hearts: a cardiovascular magnetic resonance study of papillary muscle mass and T1 mapping

scientific article published on 02 September 2016

It's not just the mitral valve - abnormal motion of the whole aorto-mitral apparatus occurs in both overt and subclinical hypertrophic cardiomyopathy.

scientific article

LGE-PSIR is an independent predictor of mortality in cardiac amyloidosis: a 250 patient prospective study

scientific article published on 3 February 2015

Late Anthracycline-Related Cardiotoxicity in Low-Risk Breast Cancer Patients

scientific article published on 01 May 2017

Left ventricular remodeling after reperfused acute myocardial infarction: insights from automated ECV mapping.

scientific article published on 27 January 2016

Limitations of the New York Heart Association functional classification system and self-reported walking distances in chronic heart failure

scientific article

Maximizing efficiency of alternation algorithms for hemodynamic optimization of the AV delay of cardiac resynchronization therapy.

scientific article published on 4 October 2010

Meta-analysis of symptomatic response attributable to the pacing component of cardiac resynchronization therapy.

scientific article published in December 2013

Meta-analysis of the comparative effects of different classes of antihypertensive agents on brachial and central systolic blood pressure, and augmentation index

scientific article

Myocardial T1 mapping

scientific article

Myocardial iron quantification using T2* and native T1mapping - a 250 patient study

Native myocardial T1 and ECV with age and gender developing normal reference ranges - a 94 healthy volunteer study.

scientific article published on 27 January 2016

Normalidad estructural con arritmia ventricular: el efecto horizonte

Novel cardiac pacemaker-based human model of periodic breathing to develop real-time, pre-emptive technology for carbon dioxide stabilisation

scientific article

Novel use of cardiac pacemakers in heart failure to dynamically manipulate the respiratory system through algorithmic changes in cardiac output

scientific article published on 23 March 2009

Organisation & models of cardio-oncology clinics.

scientific article

Patient-accessible tool for shared decision making in cardiovascular primary prevention: balancing longevity benefits against medication disutility

scientific article

Performance of automated ECV maps versus conventionally calculated ECV.

scientific article published on 3 February 2015

Precision and reproducibility of blood T1 estimation: implications of T1 star on ECV calculation.

scientific article

Prognostic Value of Late Gadolinium Enhancement Cardiovascular Magnetic Resonance in Cardiac Amyloidosis

scientific article

Provision of magnetic resonance imaging for patients with 'MR-conditional' cardiac implantable electronic devices: an unmet clinical need.

scientific article published on 02 June 2016

Pulmonary artery wave propagation and reservoir function in conscious man: impact of pulmonary vascular disease, respiration and dynamic stress tests.

scientific article

Quantification of both the area-at-risk and acute myocardial infarct size in ST-segment elevation myocardial infarction using T1-mapping

scientific article published on August 2017

Quantification of the area-at-risk by T1 and T2 mapping CMR at 3T.

scientific article published on 3 February 2015

Quantifying the paradoxical effect of higher systolic blood pressure on mortality in chronic heart failure.

scientific article published on 24 July 2008

Real-time dynamic carbon dioxide administration: a novel treatment strategy for stabilization of periodic breathing with potential application to central sleep apnea

scientific article published in November 2010

Redefining viability by cardiovascular magnetic resonance in acute ST-segment elevation myocardial infarction

scientific article published on 7 November 2017

Reproducibility of native T1 mapping using ShMOLLI and MOLLI - implications for sample size calculation.

scientific article published on 27 January 2016

Residual Myocardial Iron Following Intramyocardial Hemorrhage During the Convalescent Phase of Reperfused ST-Segment-Elevation Myocardial Infarction and Adverse Left Ventricular Remodeling.

scientific article published on October 2016

Resonance as the Mechanism of Daytime Periodic Breathing in Patients with Heart Failure.

scientific article

Response

Response to Letters Regarding Article, "Prognostic Value of Late Gadolinium Enhancement Cardiovascular Magnetic Resonance in Cardiac Amyloidosis".

scientific article published on March 2016

Reverse Myocardial Remodeling Following Valve Replacement in Patients With Aortic Stenosis.

scientific article published in February 2018

Safe use of MRI in people with cardiac implantable electronic devices

scientific article published on 29 September 2015

Serum albumin changes and multivariate dynamic risk modelling in chronic heart failure.

scientific article published in August 2014

Splenic Switch-off: A Tool to Assess Stress Adequacy in Adenosine Perfusion Cardiac MR Imaging

scientific article published on 29 April 2015

Splenic switch-off, a potential novel marker of lack of adenosine response: prevalence and measurement reproducibility.

scientific article published on 3 February 2015

Splenic switch-off, a potential novel marker of lack of adenosine response: relationship to heart rate response and demographic factors.

scientific article published on 3 February 2015

T1 mapping and T2 mapping at 3T for quantifying the area-at-risk in reperfused STEMI patients

scientific article

T1 mapping in severe aortic stenosis: insights into LV remodeling.

scientific article

T1 mapping: non-invasive evaluation of myocardial tissue composition by cardiovascular magnetic resonance

scientific article

The Right ventricle and cardiac surgery - more resilient than thought: multiparametric quantification shows altered rather than reduced function.

scientific article

The acute effects of changes to AV delay on BP and stroke volume: potential implications for design of pacemaker optimization protocols

scientific article

The arterial reservoir pressure increases with aging and is the major determinant of the aortic augmentation index

scientific article

The atrioventricular delay of cardiac resynchronization can be optimized hemodynamically during exercise and predicted from resting measurements

scientific article published on 4 December 2007

The risk of cardiac failure following metal-on-metal hip arthroplasty

scientific article published in January 2018

Ultrafast Magnetic Resonance Imaging for Iron Quantification in Thalassemia Participants in the Developing World: The TIC-TOC Study (Thailand and UK International Collaboration in Thalassaemia Optimising Ultrafast CMR).

scientific article published on August 2016

Wave Intensity Analysis Provides Novel Insights Into Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension.

scientific article published on 31 October 2017

Wave reflection predicts cardiovascular events in hypertensive individuals independent of blood pressure and other cardiovascular risk factors: an ASCOT (Anglo-Scandinavian Cardiac Outcome Trial) substudy

scientific article published on June 2010

What proportion of symptomatic side effects in patients taking statins are genuinely caused by the drug? Systematic review of randomized placebo-controlled trials to aid individual patient choice

scientific article

When is a "free" registrar in clinic not free?

scientific article published in the British Medical Journal

List of works by Charlotte Manisty

'Splenic switch-off' to detect adenosine understress; a novel method to improve test sensitivity.

A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study

A novel fully automated method for mitral regurgitant orifice area quantification

Abnormal septal convexity into the left ventricle occurs in subclinical hypertrophic cardiomyopathy ⬇️

Applicability of the iterative technique for cardiac resynchronization therapy optimization: full-disclosure, 50-sequential-patient dataset of transmitral Doppler traces, with implications for future research design and guidelines

Assessing for Cardiotoxicity from Metal-on-Metal Hip Implants with Advanced Multimodality Imaging Techniques.

Atorvastatin treatment is associated with less augmentation of the carotid pressure waveform in hypertension: a substudy of the Anglo-Scandinavian Cardiac Outcome Trial (ASCOT).

Attenuation of wave reflection by wave entrapment creates a "horizon effect" in the human aorta

Automated Extracellular Volume Fraction Mapping Provides Insights Into the Pathophysiology of Left Ventricular Remodeling Post-Reperfused ST-Elevation Myocardial Infarction

Automated speckle tracking algorithm to aid on-axis imaging in echocardiography

Automatic Measurement of the Myocardial Interstitium: Synthetic Extracellular Volume Quantification Without Hematocrit Sampling

Automatic left ventricular analysis with Inline VF performs well compared to manual analysis: results from Barts Cardiovascular Registry.

CMR myocardial texture analysis tracks different etiologies of left ventricular hypertrophy.

Can left ventricular endocardial surface roughness be measured by fractal dimension on fast gradient echo sequences?

Cardiac MRI evaluation of myocardial disease

Choosing between velocity-time-integral ratio and peak velocity ratio for calculation of the dimensionless index (or aortic valve area) in serial follow-up of aortic stenosis

Chronic iron deposit and left ventricular remodeling in reperfused STEMI patients

Clinical application of MOLLI T1* for extracellular volume calculation in healthy volunteers and aortic stenosis

Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study

Current provision for MRI scanning of patients with cardiac implantable electronic devices - a national survey of hospitals in England.

Defining left ventricular remodeling following acute ST-segment elevation myocardial infarction using cardiovascular magnetic resonance

Definitions of Outcome, Response and Effect in Imaging Research to Avoid Confusion

Detection of metallic cobalt and chromium liver deposition following failed hip replacement using T2* and R2 magnetic resonance

Development of respiratory control instability in heart failure: a novel approach to dissect the pathophysiological mechanisms

Diagnosis and Prognosis in Sudden Cardiac Arrest Survivors Without Coronary Artery Disease: Utility of a Clinical Approach Using Cardiac Magnetic Resonance Imaging.

Diagnostic performance of T1 and T2 mapping to detect intramyocardial hemorrhage in reperfused ST-segment elevation myocardial infarction (STEMI) patients

Differences in the magnitude of wave reflection account for differential effects of amlodipine- versus atenolol-based regimens on central blood pressure: an Anglo-Scandinavian Cardiac Outcome Trial substudy

Diffuse myocardial fibrosis - a therapeutic target? Proof of regression at 1-year following aortic valve replacement: the RELIEF-AS study.

Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection

Doctors should not discuss resuscitation with terminally ill patients: FOR.

Dynamic CO2 therapy in periodic breathing: a modeling study to determine optimal timing and dosage regimes

ECG, LVH and T1 changes in Fabry disease - implications for screening and understanding of the disease model.

Effect of study design on the reported effect of cardiac resynchronization therapy (CRT) on quantitative physiological measures: stratified meta-analysis in narrow-QRS heart failure and implications for planning future studies

Efficiency, reproducibility and agreement of five different hemodynamic measures for optimization of cardiac resynchronization therapy

Ejection fraction: a measure of desperation?

Evaluation of splenic switch off in a tertiary imaging centre: validation and assessment of utility

Evidence of a dominant backward-propagating "suction" wave responsible for diastolic coronary filling in humans, attenuated in left ventricular hypertrophy

Evidence that conflict regarding size of haemodynamic response to interventricular delay optimization of cardiac resynchronization therapy may arise from differences in how atrioventricular delay is kept constant

Evidence-based recommendations for PISA measurements in mitral regurgitation: systematic review, clinical and in-vitro study

First-in-man safety evaluation of renal denervation for chronic systolic heart failure: primary outcome from REACH-Pilot study

Graft-versus-host disease: a case report of a rare but reversible cause of constrictive pericarditis

Guidance for accurate and consistent tissue Doppler velocity measurement: comparison of echocardiographic methods using a simple vendor-independent method for local validation

Haemodynamic effects of changes in atrioventricular and interventricular delay in cardiac resynchronisation therapy show a consistent pattern: analysis of shape, magnitude and relative importance of atrioventricular and interventricular delay

Hematocrit, iron and HDL-cholesterol explain 90% of variation in native blood T1.

Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure

Impact of microvascular obstruction on semiautomated techniques for quantifying acute and chronic myocardial infarction by cardiovascular magnetic resonance.

Improved Exercise-Related Skeletal Muscle Oxygen Consumption Following Uptake of Endurance Training Measured Using Near-Infrared Spectroscopy

Incidence of left ventricular thrombi in reperfused STEMI patients detected by contrast-enhanced CMR.

Induction of oscillatory ventilation pattern using dynamic modulation of heart rate through a pacemaker

Insight into hypertrophied hearts: a cardiovascular magnetic resonance study of papillary muscle mass and T1 mapping

It's not just the mitral valve - abnormal motion of the whole aorto-mitral apparatus occurs in both overt and subclinical hypertrophic cardiomyopathy.

LGE-PSIR is an independent predictor of mortality in cardiac amyloidosis: a 250 patient prospective study

Late Anthracycline-Related Cardiotoxicity in Low-Risk Breast Cancer Patients

Left ventricular remodeling after reperfused acute myocardial infarction: insights from automated ECV mapping.

Limitations of the New York Heart Association functional classification system and self-reported walking distances in chronic heart failure

Maximizing efficiency of alternation algorithms for hemodynamic optimization of the AV delay of cardiac resynchronization therapy.

Meta-analysis of symptomatic response attributable to the pacing component of cardiac resynchronization therapy.

Meta-analysis of the comparative effects of different classes of antihypertensive agents on brachial and central systolic blood pressure, and augmentation index

Myocardial T1 mapping

Myocardial iron quantification using T2* and native T1mapping - a 250 patient study

Native myocardial T1 and ECV with age and gender developing normal reference ranges - a 94 healthy volunteer study.

Normalidad estructural con arritmia ventricular: el efecto horizonte

Novel cardiac pacemaker-based human model of periodic breathing to develop real-time, pre-emptive technology for carbon dioxide stabilisation

Novel use of cardiac pacemakers in heart failure to dynamically manipulate the respiratory system through algorithmic changes in cardiac output

Organisation & models of cardio-oncology clinics.

Patient-accessible tool for shared decision making in cardiovascular primary prevention: balancing longevity benefits against medication disutility

Performance of automated ECV maps versus conventionally calculated ECV.

Precision and reproducibility of blood T1 estimation: implications of T1 star on ECV calculation.

Prognostic Value of Late Gadolinium Enhancement Cardiovascular Magnetic Resonance in Cardiac Amyloidosis

Provision of magnetic resonance imaging for patients with 'MR-conditional' cardiac implantable electronic devices: an unmet clinical need.

Pulmonary artery wave propagation and reservoir function in conscious man: impact of pulmonary vascular disease, respiration and dynamic stress tests.

Quantification of both the area-at-risk and acute myocardial infarct size in ST-segment elevation myocardial infarction using T1-mapping

Quantification of the area-at-risk by T1 and T2 mapping CMR at 3T.

Quantifying the paradoxical effect of higher systolic blood pressure on mortality in chronic heart failure.

Real-time dynamic carbon dioxide administration: a novel treatment strategy for stabilization of periodic breathing with potential application to central sleep apnea

Redefining viability by cardiovascular magnetic resonance in acute ST-segment elevation myocardial infarction

Reproducibility of native T1 mapping using ShMOLLI and MOLLI - implications for sample size calculation.

Residual Myocardial Iron Following Intramyocardial Hemorrhage During the Convalescent Phase of Reperfused ST-Segment-Elevation Myocardial Infarction and Adverse Left Ventricular Remodeling.

Resonance as the Mechanism of Daytime Periodic Breathing in Patients with Heart Failure.