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List of works by Ralf Weiskirchen

136 ENDOGLIN DEFICIENCY IN HEPATIC STELLATE CELLS HAS A DIFFERENTIAL EFFECT ON LIVER FIBROSIS AND TGF-b SIGNALLING IN TWO EXPERIMENTAL MODELS OF MURINE LIVER FIBROSIS

137 TNF-RECEPTOR 1-DEPENDENT SIGNALLING DETERMINES THE PROGRESSION OF NEMO-MEDIATED HEPATITIS

283 A NON-REDUNDANT ROLE OF THE PLATELET-DERIVED CHEMOKINE CXCL4 (PF4) IN EXPERIMENTAL LIVER FIBROSIS

491 THE BMP-7 PATHWAY IN HEPATIC STELLATE CELLS AND HEPATOCYTES AND ITS ANTAGONISTIC EFFECT ON THE TGF-BETA1 SIGNALING PATHWAY

51 GENE POLYMORPHISMS WITHIN THE CODING REGION OF TGF-BETA1 AFFECT CELLULAR SYNTHESIS, SECRETION AND PROCESSING OF TGF-BETA1 VIA THE LATENT TGF-BETA BINDING PROTEIN-1 (LTBP-1)

article

599 TRANSDUCTION OF ADENOVIRUS ENCODING DOMINANT-NEGATIVE SOLUBLE PDGFRβ IMPROVES SYSTEMIC HEMODYNAMICS, PORTAL PRESSURE AND HEPATIC FIBROSIS IN RATS CHRONICALLY TREATED WITH CCL4

920 ANTIFIBROTIC PROPERTIES OF NOV/CCN3 IN LIVER

962 HEPATIC ENDOGLIN EXPRESSION IS UPREGULATED DURING TRANSDIFFERENTIATION OF HSC TO MFB AND MODULATES PROFIBROGENIC RESPONSES IN MYOFIBROBLAST-LIKE CELLS

article

969 CYCLIN E1 CONTROLS THE CELL CYCLE ACTIVITY OF HEPATIC STELLATE CELLS AND TRIGGERS FIBROGENESIS IN MICE

999 HUMAN MONOCYTE SUBSETS ACCUMULATE INTRAHEPATICALLY IN LIVER CIRRHOSIS AND DIFFERENTIALLY INTERACT WITH HEPATIC STELLATE CELLS

A complex network of intra- and intercellular mediators regulate cellular activation and transdifferentiation of hepatic stellate cells

A functional variation in CHI3L1 is associated with severity of liver fibrosis and YKL-40 serum levels in chronic hepatitis C infection

A novel proximal -13914G>A base replacement in the vicinity of the common-13910T/C lactase gene variation results in an atypical LightCycler melting curve in testing with the MutaREAL Lactase test.

scientific article

A novel, dual role of CCN3 in experimental glomerulonephritis: pro-angiogenic and antimesangioproliferative effects.

scientific article published in May 2012

A yellow bullet against the drivers of hepatic fibrogenesis

scientific article published on 01 August 2008

AMINO-TERMINAL LIM DOMAIN FROM QUAIL CYSTEINE AND GLYCINE-RICH PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE

Aberrant cell cycle progression and endoreplication in regenerating livers of mice that lack a single E-type cyclin

scientific article published on 13 May 2009

Abrogation of both short and long forms of latent transforming growth factor-β binding protein-1 causes defective cardiovascular development and is perinatally lethal

scientific article published on 21 March 2015

Accurate Measurement of Copper Overload in an Experimental Model of Wilson Disease by Laser Ablation Inductively Coupled Plasma Mass Spectrometry

scientific article published on 16 September 2020

Accurate standardization and normalization of hepatic metal contents in Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS)

Activation of TGF-beta within cultured hepatocytes and in liver injury leads to intracrine signaling with expression of connective tissue growth factor

scientific article published on 04 February 2008

Activation of hepatic stellate cells is associated with cytokine expression in thioacetamide-induced hepatic fibrosis in mice

scientific article

Activation of latent TGF-β1 within the hepatocyte contributes to connective tissue growth factor (CTGF/CCN2) expression via entirely intracellular signalling

Activation of latent TGF-β1 within the hepatocyte contributes to connective tissue growth factor (CTGF/CCN2) expression via entirely intracellular signalling

Adenoviral CCN gene transfers induce in vitro and in vivo endoplasmic reticulum stress and unfolded protein response

scientific article published on 21 July 2016

Adenoviral CCN3/NOV gene transfer fails to mitigate liver fibrosis in an experimental bile duct ligation model because of hepatocyte apoptosis

article

Adenoviral dominant-negative soluble PDGFRβ improves hepatic collagen, systemic hemodynamics, and portal pressure in fibrotic rats

scientific article published on 20 July 2012

Adenoviral expression of a transforming growth factor-beta1 antisense mRNA is effective in preventing liver fibrosis in bile-duct ligated rats

scientific article

Adenoviral-mediated transfer of p53 or retinoblastoma protein blocks cell proliferation and induces apoptosis in culture-activated hepatic stellate cells

scientific article

Adiponectin as a modulator of hepatic fibrosis in chronic HCV-Infection

Adiponectin as a putative modulator of hepatitis in chronic HCV-infection

Advances in the clinical use of collagen as biomarker of liver fibrosis

scientific article published on 24 September 2020

Age-independent anti-Müllerian hormone (AMH) standard deviation scores to estimate ovarian function

scientific article published on 18 April 2017

Age-specific reference values improve the diagnostic performance of AMH in polycystic ovary syndrome

scientific article published on 18 February 2020

All You Can Feed: Some Comments on Production of Mouse Diets Used in Biomedical Research with Special Emphasis on Non-Alcoholic Fatty Liver Disease Research

scientific article published on 07 January 2020

Altered factor VII activating protease expression in murine hepatic fibrosis and its influence on hepatic stellate cells

scientific article published on 15 October 2008

Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis

scientific article

An unusual melting curve profile in LightCycler multiplex genotyping of the hemochromatosis H63D/C282Y gene mutations

article

An update on the recent advances in antifibrotic therapy

scientific article published on 03 October 2018

Analysis of antigen-presenting functionality of cultured rat hepatic stellate cells and transdifferentiated myofibroblasts

scientific article

Analysis of antigen-presenting functionality of rat hepatic stellate cells

Analysis of polymorphic TGFB1 codons 10, 25, and 263 in a German patient group with non-syndromic cleft lip, alveolus, and palate compared with healthy adults

scientific article published on 22 June 2004

Analysis of the transforming growth factor-beta1 (TGF-beta1) codon 25 gene polymorphism by LightCycler-analysis in patients with chronic hepatitis C infection

scientific article published in December 2003

Analysis of transforming growth factor-β1 gene polymorphisms in patients with Hepatitis C infection

article

Analytical evaluation of the novel soluble fms-like tyrosine kinase 1 and placental growth factor assays for the diagnosis of preeclampsia

scientific article published on 27 June 2015

Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice

scientific article published on 18 October 2010

Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver

scientific article published on 17 February 2020

Antifibrotic effects of CCN1/CYR61 in primary portal myofibroblasts through induction of reactive oxygen species and resulting apoptosis

article published in 2014

Antifibrotic effects of CXCL9 and its receptor CXCR3 in livers of mice and humans

scientific article

Antigen-presenting function of rat hepatic stellate cells

Antisense strategy against PDGF B-chain proves effective in preventing experimental liver fibrogenesis

scientific journal article

Apoptosis and Pharmacological Therapies for Targeting Thereof for Cancer Therapeutics

scientific article published in 2022

Assignment1 of CSRP1 encoding the LIM domain protein CRP1, to human chromosome 1q32 by fluorescence in situ hybridization.

scientific article

Association of Serum Calprotectin Concentrations with Mortality in Critically Ill and Septic Patients

scientific article published on 23 November 2020

Assoziation von CCBP2, einem Scavenger-Rezeptor für inflammatorische Chemokine, mit der Leberentzündung im Tiermodell und bei Patienten mit chronischer Hepatitis C

Atypical Melting Curve Resulting from Genetic Variation in the 3' Untranslated Region at Position 20218 in the Prothrombin Gene Analyzed with the LightCycler Factor II (Prothrombin) G20210A Assay

article

Auftreten der Gln223Arg-Mutation im Gen des Leptinrezeptors und der Pro12Ala Mutation im Gen des PPARγ bei Patienten mit chronischer Hepatitis C

BMP-7 as antagonist of organ fibrosis

scientific article published on June 2009

BMP-7 counteracting TGF-beta1 activities in organ fibrosis

scientific article published on June 2013

BMP-7/TGF-β1 signalling in myoblasts: components involved in signalling and BMP-7-dependent blockage of TGF-β-mediated CTGF expression

scientific article

Bedeutung der Chemokine CCL5 (RANTES) und CXCL4 (PF4) bei Patienten mit chronischen Lebererkrankungen

Bile duct ligation in mice: induction of inflammatory liver injury and fibrosis by obstructive cholestasis

scientific article

Bioimaging of copper deposition in Wilson's diseases mouse liver by laser ablation inductively coupled plasma mass spectrometry imaging (LA-ICP-MSI)

Biomarkers of hepatic fibrosis, fibrogenesis and genetic pre-disposition pending between fiction and reality

scientific article published on September 2007

Biomarkers of liver fibrosis: clinical translation of molecular pathogenesis or based on liver-dependent malfunction tests

scientific article published on 27 February 2007

Bispheric Coordinative Structuring in a Zinc Finger Protein: NMR Analysis of a Point Mutant of the Carboxy-Terminal LIM Domain of Quail Cysteine- and Glycine-Rich Protein CRP2

article published in 1998

Blockade of NLRP3 expression in primary hepatocytes by inhibitors of NF-κB signalling

scholarly article by SG Boaru et al published 13 January 2014 in Zeitschrift fuer Gastroenterologie

Bone Morphogenetic Protein-8B Expression is Induced in Steatotic Hepatocytes and Promotes Hepatic Steatosis and Inflammation In Vitro.

scientific article published on 15 May 2019

Bone morphogenetic protein-7 in focus: A member of the transforming growth factor-β superfamily is implicated in the maintenance of liver health

article

Bone morphogenetic protein–7 (BMP–7), a neglected player in hepatic fibrosis?

Brain copper storage after genetic long-term correction in a mouse model of Wilson disease.

scientific article

CCN proteins in normal and injured liver ⬇️

scientific article published on January 1, 2011

CCN1/CYR61 overexpression in hepatic stellate cells induces ER stress-related apoptosis

scientific article published on 26 October 2015

CCN3/NOV small interfering RNA enhances fibrogenic gene expression in primary hepatic stellate cells and cirrhotic fat storing cell line CFSC.

scientific article published on 5 July 2011

CSRP2, TIMP-1, and SM22alpha promoter fragments direct hepatic stellate cell-specific transgene expression in vitro, but not in vivo

scientific article published on February 2004

CXC chemokine ligand 4 (Cxcl4) is a platelet-derived mediator of experimental liver fibrosis

scientific article published in April 2010

Ccn1, a molecular switch that imposes a self-limiting control on inflammation and wound healing in a multitude of organs?

scientific article

Cellular and molecular functions of hepatic stellate cells in inflammatory responses and liver immunology

scientific article published on December 2014

Changes of the hepatic proteome in murine models for toxically induced fibrogenesis and sclerosing cholangitis

scientific article

Changing the pathogenetic roadmap of liver fibrosis? Where did it start; where will it go?

scientific article published on 26 May 2008

Characterization of Sno expression in malignant melanoma

scientific article (publication date: May 2005)

Characterization of TGF-β-dependent signaling-pathways for CTGF/CCN2 expression in hepatocytes of normal and injured livers

Chemokine Cxcl9 attenuates liver fibrosis-associated angiogenesis in mice

scientific article published on 01 May 2012

Chronic Carbon Tetrachloride Applications Induced Hepatocyte Apoptosis in Lipocalin 2 Null Mice Through Endoplasmic Reticulum Stress and Unfolded Protein Response

scientific article published on 23 July 2020

Chronic mineral oil administration increases hepatic inflammation in wild type mice compared to lipocalin 2 null mice

scientific article published on 13 September 2021

Circulating factor VII activating protease (FSAP) is associated with clinical outcome in acute coronary syndrome

scientific article

Circulating retinol binding protein 4 in critically ill patients before specific treatment: prognostic impact and correlation with organ function, metabolism and inflammation

scientific article published on 8 October 2010

Clinical features of Wilson disease.

scientific article

Clinical relevance and cellular source of elevated soluble urokinase plasminogen activator receptor (suPAR) in acute liver failure.

scientific article

Clinical relevance of copeptin plasma levels as a biomarker of disease severity and mortality in critically ill patients

scientific article published on 05 July 2018

Combining GP73 with liver stiffness measurements: A proof-of-concept for non-invasive fibrosis assessment in antiviral-naïve HBV patients.

scientific article published in November 2017

Commentary on "Reregulation of hepatic stellate cell contraction and cirrhotic portal hypertension by Wnt/β-catenin signaling via interaction with Gli1"

scientific article published on 21 October 2020

Commentary: Montelukast Prevents Mice Against Acetaminophen-Induced Liver Injury

scientific article published on 25 October 2019

Common heterozygous hemochromatosis gene mutations are risk factors for inflammation and fibrosis in chronic hepatitis C

article

Comparative evaluation of gene delivery devices in primary cultures of rat hepatic stellate cells and rat myofibroblasts

scientific article

Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans

scientific article published on 3 July 2005

Conditional cell transformation by doxycycline-controlled expression of the MC29 v-myc allele.

scientific article published on January 1999

Connective tissue growth factor is a Smad2 regulated amplifier of transforming growth factor beta actions in hepatocytes--but without modulating bone morphogenetic protein 7 signaling

scientific article published in June 2009

Contribution of E-type cyclins to hepatic fibrosis in human and mice

Copy number variation of the CCL3L1 gene in chronic HCV infection: Influence on susceptibility and fibro-inflammatory response

article

Corrigendum to “Factor VII activating protease (FSAP) exerts anti-inflammatory and anti-fibrotic effects in liver fibrosis in mice and men” [J Hepatol 2013;58:104–111]

scholarly article published in Journal of Hepatology

Corrigendum to “Inhibitory effect of soluble PDGF-β receptor in culture-activated hepatic stellate cells” [Biochem. Biophys. Res. Commun. 317 (2004) 451–462]

article

Cross-method comparison of serum androstenedione measurement with respect to the validation of a new fully automated chemiluminescence immunoassay

scientific article published on 24 September 2018

Cryopreservation of Hepatic Stellate Cells: A Valid Method for Banking Progenitor Cells of Liver Fibrogenesis

Cryopreservation of hepatic stellate cells

scientific article published on 2 August 2005

Current Status in Testing for Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH)

scientific article published on 07 August 2019

Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma

scientific article

Cyclin E1 controls proliferation of hepatic stellate cells and is essential for liver fibrogenesis in mice

scientific article published on 12 July 2012

Cyclin E1 is an essential pro-fibrotic factor in the liver

Cystatin C is expressed in hepatic stellate cells (HSC) and upregulated during transdifferentiation to myofibroblasts (MFB)

DIGE (Difference In Gel Electrophoresis) Analyse von BALB-Abcb4-/- Mäusen zeigt eine verminderte Expression von Selenium binding protein 2 in der Leber

Data on Lipocalin 2 and phosphatidylinositol 3-kinase signaling in a methionine- and choline-deficient model of non-alcoholic steatohepatitis

scientific article published on July 2017

Decreased CTRP3 Plasma Concentrations Are Associated with Sepsis and Predict Mortality in Critically Ill Patients

scientific article published on 21 June 2019

Deficiency in four and one half LIM domain protein 2 (FHL2) aggravates liver fibrosis in mice

scientific article

Defining the genetic characteristics of human hepatic stellate cell line LX-2 by spectral karyotyping and short tandem repeat genotyping

Deletion of Perilipin 5 Protects Against Hepatic Injury in Nonalcoholic Fatty Liver Disease via Missing Inflammasome Activation

scientific article published on 28 May 2020

Deletion of the platelet derived chemokine PF4 (CXCL4) limits liver fibrosis in vivo

Der Komplementfaktor 5 (C5) beeinflusst die Fibrose-Suszeptibilität im Inzuchtmausmodell

Der Multiligandenrezeptor Megalin–ein neuer Marker für hepatische Sternzellen

Determination of copper poisoning in Wilson's disease using laser ablation inductively coupled plasma mass spectrometry.

scientific article published in April 2019

Development and evaluation of an open source Delphi-based software for morphometric quantification of liver fibrosis

scientific article published on 17 June 2010

Diagnostic value of the quantitative HBsAg determination in hepatitis B infections

scientific article published on 7 April 2016

Die PDGF-BB-vermittelte Stimulation Hepatischer Sternzellen wird in vitro durch die Plasmaprotease FSAP (Faktor VII Aktivierende Protease) inhibiert

Die genetische Deletion des von Thrombozyten sezernierten Chemokins PF4 (CXCL4) reduziert die Leberfibrose in vivo

Diethylnitrosamine (DEN)-induced carcinogenic liver injury in mice

scientific article published in April 2015

Differential effects of TGF-β on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes

scientific article published on 26 June 2007

Differential regulation of Id1 expression by TGF-β1 in HepG2 cells

Differential regulation of Lipocalin 2 (LCN2) in doxorubicin-resistant 4T1 triple negative breast cancer cells

scientific article published on 03 August 2020

Differentiation and effects of TGF-β1 and IL-3 signaling on primary murine endoglin deficient mast cells

Disorders of the glucose metabolism correlate with the phenotype and the severity in women with polycystic ovary syndrome

scientific article published on 11 March 2020

Disruption of intermolecular disulfide bonds in PDGF-BB dimers by N-acetyl-L-cysteine does not prevent PDGF signaling in cultured hepatic stellate cells

scientific article

Disruption of the latent transforming growth factor-beta binding protein-1 gene causes alteration in facial structure and influences TGF-beta bioavailability

scientific article published on 29 August 2007

Disturbed zinc homeostasis in diabetic patients by in vitro and in vivo analysis of insulinomimetic activity of zinc

scientific article published on 07 March 2012

Diversity of TGF-β-signaling in rat hepatic stellate cells and in myofibroblasts

Does it matter not only how much but also when we eat to induce fatty liver?

scientific article published on 01 September 2011

Dominant-negative soluble PDGF-beta receptor inhibits hepatic stellate cell activation and attenuates liver fibrosis

scientific article published in June 2004

Dual CTLA-4 and PD-L1 Blockade Inhibits Tumor Growth and Liver Metastasis in a Highly Aggressive Orthotopic Mouse Model of Colon Cancer

scientific article published on 11 August 2019

Dysregulated mesenchymal PDGFR-β drives kidney fibrosis

scientific article published on 14 January 2020

ENG

ENG

Editorial for focused issue "Wilson Disease: From Genetics to Management of Disease".

scientific article published in April 2019

Editorial: Liver Myofibroblasts

scientific article published on 5 August 2016

Editorial: Macrophages in Liver Disease

scientific article published on 04 August 2020

Effects of N-acetylcysteine and L-Cysteine on TGF-beta Signaling in Culture-activated Hepatic Stellate Cells

article

Effekt von Endoglin auf die Differenzierung und das Signalling in einer neuen Col-GFP-exprimierenden immortalisierten murinen Sternzell-Linie

Elastin imaging enables noninvasive staging and treatment monitoring of kidney fibrosis

scientific article published on 01 April 2019

Elevated CTRP1 Plasma Concentration Is Associated with Sepsis and Pre-Existing Type 2 Diabetes Mellitus in Critically Ill Patients

scientific article published on 11 May 2019

Elevated MR-proANP plasma concentrations are associated with sepsis and predict mortality in critically ill patients

scientific article published on 12 December 2019

Elevated asymmetric dimethylarginine levels predict short- and long-term mortality risk in critically ill patients

scientific article published on 14 August 2013

Elevated circulating soluble interleukin-2 receptor in patients with chronic liver diseases is associated with non-classical monocytes

scientific article

Endoglin Trafficking/Exosomal Targeting in Liver Cells Depends on N-Glycosylation

scientific article published on 28 August 2019

Endoglin and its involvement in transdifferentiation of hepatic stellate cells

Endoglin differentially modulates antagonistic transforming growth factor-beta1 and BMP-7 signaling

scientific journal article

Endoglin in human liver disease and murine models of liver fibrosis - a protective factor against liver fibrosis

scientific article published on 20 September 2017

Endoglin in liver fibrogenesis: Bridging basic science and clinical practice

scientific article

Endoglin is upregulated and counteracts profibrogenic responses in transdifferentiating hepatic stellate cells

article

Endoglin modulates Smad-dependent and Smad-independent pathways to regulate proliferation, migration and profibrogenic responses in myofibroblasts

article

Endoglin: An 'Accessory' Receptor Regulating Blood Cell Development and Inflammation

scientific article published on 03 December 2020

Erfolgreiche Fibrosetherapie mittels proteolytisch inaktiver MMP–9 Mutanten: ein gentherapeutischer Ansatz

Erratum to “Proteomic tissue profiling for the improvement of grading of noninvasive papillary urothelial neoplasia” [Clinical Biochemistry 45 (2012) 7–11]

scholarly article published in Clinical Biochemistry

Establishment of novel innovative bioimaging techniques of metals by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) for diagnosis of liver damage

Evaluation of a novel reverse-hybridization StripAssay for typing DNA variants useful in diagnosis of adult-type hypolactasia

scientific article

Evidence for a heterodimeric structure of megalin in liver macrophages

article

Evolving concepts of liver fibrogenesis provide new diagnostic and therapeutic options

scientific article

Exercise-Induced Release of Pharmacologically Active Substances and Their Relevance for Therapy of Hepatic Injury

scientific article

Experience with the first fully automated chemiluminescence immunoassay for the quantification of 1α, 25-dihydroxy-vitamin D

scientific article published on 01 April 2015

Experimental liver fibrosis research: update on animal models, legal issues and translational aspects

scientific article published on October 2013

Expression analysis of CCN1/CYR61 in primary liver cells and in models of experimental liver fibrogenesis

Expression analysis of inflammasomes in experimental models of inflammatory and fibrotic liver disease

scientific article published on 28 November 2012

Expression and TGF-beta modulation of connective tissue growth factor (CTGF) in hepatic stellate cells and hepatocytes

Expression and function of S-endoglin, a rat specific splice variant of endoglin, in liver cells

Expression and functional analysis of endoglin in isolated liver cells and its involvement in fibrogenic Smad signalling

scientific journal article

Expression of pleiotrophin and its receptors in hepatic cells and in activated hepatic stellate cells (HSCs)– Pleiotrophin in hepatic stellate cells

Expression of smooth muscle cell markers in activated hepatic stellate cells is connected to MAP kinase regulated transcription levels of serum response factor (SRF)

Expression of the cysteine protease inhibitor cystatin C in hepatic stellate cells is upregulated during transdifferentiation

Expression of the megalin C-terminal fragment by macrophages during liver fibrogenesis in mice.

scientific article

Expression profile and functional activity of Platelet-derived growth factor-C and -D in bile duct-ligated rat livers and transdifferentiating hepatic stellate cells

Expression, Reinigung und quantitative in vitro Charakterisierung proteolytisch inaktiver MMP-9-Mutanten als TIMP-1 Antagonisten

Factor VII activating protease (FSAP) exerts anti-inflammatory and anti-fibrotic effects in liver fibrosis in mice and men

scientific article published on 16 September 2012

Factor VII activating protease (FSAP): a novel protective factor in liver fibrosis

scientific article published on 26 March 2014

Factor seven ativating potease (FSAP) levels during normal pregnancy and in women using oral contraceptives

scientific article

Faculty of 1000 evaluation for 15-deoxy-Delta(12,14)-prostaglandin J(2) inhibits fibrogenic response in human hepatoma cells

Faculty of 1000 evaluation for A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells

Faculty of 1000 evaluation for A gain-of-function mutation in the PDGFR-beta alters the kinetics of injury response in liver and skin

Faculty of 1000 evaluation for A rapid and sensitive bioassay to measure bone morphogenetic protein activity

Faculty of 1000 evaluation for Activation of platelet-derived growth factor receptor alpha contributes to liver fibrosis

Faculty of 1000 evaluation for An unbiased stereological study on subpopulations of rat liver macrophages and on their numerical relation with the hepatocytes and stellate cells

Faculty of 1000 evaluation for Antitumor activity of a novel antisense oligonucleotide against Akt1

Faculty of 1000 evaluation for Autoantibodies in Autoimmune Hepatitis: Can Epitopes Tell Us about the Etiology of the Disease?

Faculty of 1000 evaluation for CD271 identifies functional human hepatic stellate cells, which localize in peri-sinusoidal and portal areas in liver after partial hepatectomy

Faculty of 1000 evaluation for Casticin attenuates liver fibrosis and hepatic stellate cell activation by blocking TGF-β/Smad signaling pathway

Faculty of 1000 evaluation for Cell-type-resolved quantitative proteomics of murine liver

Faculty of 1000 evaluation for Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice

Faculty of 1000 evaluation for Cryptogenic cirrhosis and sitosterolemia: A treatable disease if identified but fatal if missed

Faculty of 1000 evaluation for Current and future pharmacological therapies for NAFLD/NASH

scholarly article published 22 June 2018

Faculty of 1000 evaluation for Current and upcoming pharmacotherapy for non-alcoholic fatty liver disease

Faculty of 1000 evaluation for Depletion of Thymosin β4 Promotes the Proliferation, Migration, and Activation of Human Hepatic Stellate Cells

Faculty of 1000 evaluation for Development of Adenoviral Delivery Systems to Target Hepatic Stellate Cells In Vivo

article

Faculty of 1000 evaluation for Diagnostic autoantibodies for autoimmune liver diseases

Faculty of 1000 evaluation for Diagnostic considerations for cholestatic liver disease

Faculty of 1000 evaluation for Distinct populations of hepatic stellate cells in the mouse liver have different capacities for retinoid and lipid storage

Faculty of 1000 evaluation for Effect of neutralizing sera on factor x-mediated adenovirus serotype 5 gene transfer

article

Faculty of 1000 evaluation for Effect of reversine on cell cycle, apoptosis, and activation of hepatic stellate cells

Faculty of 1000 evaluation for Enoxaparin does not ameliorate liver fibrosis or portal hypertension in rats with advanced cirrhosis

Faculty of 1000 evaluation for Enoxaparin reduces hepatic vascular resistance and portal pressure in cirrhotic rats

Faculty of 1000 evaluation for Epidemiology of hepatitis B virus (HBV) and hepatitis C virus (HCV) related hepatocellular carcinoma

scholarly article published 22 June 2018

Faculty of 1000 evaluation for Fate-determining mechanisms in epithelial-myofibroblast transition: major inhibitory role for Smad3

Faculty of 1000 evaluation for Fecal microbiota manipulation prevents dysbiosis and alcohol-induced liver injury in mice

scholarly article published 22 June 2018

Faculty of 1000 evaluation for Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver

Faculty of 1000 evaluation for Food components with antifibrotic activity and implications in prevention of liver disease

Faculty of 1000 evaluation for Fructose and sugar: A major mediator of non-alcoholic fatty liver disease

scholarly article published 22 June 2018

Faculty of 1000 evaluation for Galectin-3 regulates inflammasome activation in cholestatic liver injury

Faculty of 1000 evaluation for Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure

article

Faculty of 1000 evaluation for Garlic extract attenuating rat liver fibrosis by inhibiting TGF-β1

Faculty of 1000 evaluation for Gene expression profiling and functional assays of activated hepatic stellate cells suggest that myocardin has a role in activation

article

Faculty of 1000 evaluation for Global prevalence, treatment, and prevention of hepatitis B virus infection in 2016: a modelling study

Faculty of 1000 evaluation for Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease

Faculty of 1000 evaluation for Helicobacter pylori accelerates hepatic fibrosis by sensitizing transforming growth factor-β1-induced inflammatory signaling

Faculty of 1000 evaluation for Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin

Faculty of 1000 evaluation for Hepatic metabolism of retinoids and disease associations

article published in 2011

Faculty of 1000 evaluation for Hepatic stellate cells are an important cellular site for β-carotene conversion to retinoid

Faculty of 1000 evaluation for Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver

Faculty of 1000 evaluation for High-yield and high-purity isolation of hepatic stellate cells from normal and fibrotic mouse livers

Faculty of 1000 evaluation for Human antigen R contributes to hepatic stellate cell activation and liver fibrosis

Faculty of 1000 evaluation for Hydatid cyst fluid promotes peri-cystic fibrosis in cystic echinococcosis by suppressing miR-19 expression

Faculty of 1000 evaluation for Identification of genes for hereditary hemochromatosis

article

Faculty of 1000 evaluation for In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses

article

Faculty of 1000 evaluation for Increased Expression of TGF-β1 in Correlation with Liver Fibrosis during Echinococcus granulosus Infection in Mice

Faculty of 1000 evaluation for Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors

Faculty of 1000 evaluation for Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration

Faculty of 1000 evaluation for Lipocalin 2 drives neutrophilic inflammation in alcoholic liver disease

Faculty of 1000 evaluation for Lipocalin-2 mediates non-alcoholic steatohepatitis by promoting neutrophil-macrophage crosstalk via the induction of CXCR2

Faculty of 1000 evaluation for Lipocalin-2 negatively modulates the epithelial-to-mesenchymal transition in hepatocellular carcinoma through the epidermal growth factor (TGF-beta1)/Lcn2/Twist1 pathway

Faculty of 1000 evaluation for Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver

Faculty of 1000 evaluation for Liver Disease in Alpha-1 Antitrypsin Deficiency: Current Approaches and Future Directions

Faculty of 1000 evaluation for Long-term metabolic correction of Wilson's disease in a murine model by gene therapy

article

Faculty of 1000 evaluation for Losartan prevents portal hypertension-induced, redox-mediated endothelial dysfunction in the mesenteric artery in rats

Faculty of 1000 evaluation for Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial-mesenchymal transition in liver injury

Faculty of 1000 evaluation for Mitochondrial uncouplers inhibit hepatic stellate cell activation

Faculty of 1000 evaluation for Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression

Faculty of 1000 evaluation for Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy

Faculty of 1000 evaluation for NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation and fibrosis

Faculty of 1000 evaluation for Neutrophil gelatinase-associated lipocalin is a biomarker of acute-on-chronic liver failure and prognosis in cirrhosis

scholarly article published 20 May 2016

Faculty of 1000 evaluation for Non-Canonical Wnt Predominates in Activated Rat Hepatic Stellate Cells, Influencing HSC Survival and Paracrine Stimulation of Kupffer Cells

Faculty of 1000 evaluation for PPM1A dephosphorylates RanBP3 to enable efficient nuclear export of Smad2 and Smad3

Faculty of 1000 evaluation for Paracrine signalling in colorectal liver metastases involving tumor cell-derived PDGF-C and hepatic stellate cell-derived PAK-2

Faculty of 1000 evaluation for Perilipin 5 restores the formation of lipid droplets in activated hepatic stellate cells and inhibits their activation

Faculty of 1000 evaluation for Platelet-Derived Growth Factor Receptor Alpha Contributes to Human Hepatic Stellate Cell Proliferation and Migration

Faculty of 1000 evaluation for Primary sclerosing cholangitis - a comprehensive review

article

Faculty of 1000 evaluation for Protective effects of thymosin β4 on carbon tetrachloride-induced acute hepatotoxicity in rats

Faculty of 1000 evaluation for Quiescent Hepatic Stellate Cells Functionally Contribute to the Hepatic Innate Immune Response via TLR3

Faculty of 1000 evaluation for RNA interference targeting the platelet-derived growth factor receptor beta subunit ameliorates experimental hepatic fibrosis in rats

Faculty of 1000 evaluation for Recent Insights into the Pathogenesis of Nonalcoholic Fatty Liver Disease

Faculty of 1000 evaluation for Reference gene selection for real-time RT-PCR in eight kinds of rat regenerating hepatic cells

article

Faculty of 1000 evaluation for Restoration of a healthy intestinal microbiota normalizes portal hypertension in a rat model of nonalcoholic steatohepatitis

Faculty of 1000 evaluation for Selective targeting of lysyl oxidase-like 2 (LOXL2) suppresses hepatic fibrosis progression and accelerates its reversal

Faculty of 1000 evaluation for Senescence of activated stellate cells limits liver fibrosis

Faculty of 1000 evaluation for Sorafenib attenuates the portal hypertensive syndrome in partial portal vein ligated rats

Faculty of 1000 evaluation for Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms

Faculty of 1000 evaluation for TLR4 enhances TGF-beta signaling and hepatic fibrosis

article published in 2007

Faculty of 1000 evaluation for Telbivudine versus lamivudine in patients with chronic hepatitis B

Faculty of 1000 evaluation for The ASK1 inhibitor selonsertib in patients with nonalcoholic steatohepatitis: A randomized, phase 2 trial

Faculty of 1000 evaluation for The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway

Faculty of 1000 evaluation for The FLS (Fatty liver Shionogi) mouse reveals local expressions of lipocalin-2, CXCL1 and CXCL9 in the liver with non-alcoholic steatohepatitis

Faculty of 1000 evaluation for The Matricellular Protein CCN1 Promotes Regression of Liver Fibrosis through Induction of Cellular Senescence in Hepatic Myofibroblasts

Faculty of 1000 evaluation for The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

Faculty of 1000 evaluation for The T/G 13915 variant upstream of the lactase gene (LCT) is the founder allele of lactase persistence in an urban Saudi population

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Faculty of 1000 evaluation for The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013

Faculty of 1000 evaluation for The gut microbiota: A new potential driving force in liver cirrhosis and hepatocellular carcinoma

Faculty of 1000 evaluation for The matricellular protein CCN1 suppresses hepatocarcinogenesis by inhibiting compensatory proliferation

Faculty of 1000 evaluation for The niche of stellate cells within rat liver

Faculty of 1000 evaluation for The pentraxins PTX3 and SAP in innate immunity, regulation of inflammation and tissue remodelling

Faculty of 1000 evaluation for Therapeutic strategies for alcoholic liver disease: Focusing on inflammation and fibrosis (Review)

Faculty of 1000 evaluation for Thiazolidinediones and Advanced Liver Fibrosis in Nonalcoholic Steatohepatitis: A Meta-analysis

Faculty of 1000 evaluation for Transcriptional activation of the beta-catenin gene at the invasion front of colorectal liver metastases

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Faculty of 1000 evaluation for Up-regulation of RACK1 by TGF-β1 promotes hepatic fibrosis in mice

Faculty of 1000 evaluation for Vinculin and cellular retinol-binding protein-1 are markers for quiescent and activated hepatic stellate cells in formalin-fixed paraffin embedded human liver

Faculty of 1000 evaluation for Viral hepatitis and liver cancer

Faculty of 1000 evaluation for norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis

Faculty of 1000 evaluation for β-PDGF Receptor Expressed by Hepatic Stellate Cells Regulates Fibrosis in Murine Liver Injury, but Not Carcinogenesis

False-negative results in the immunoassay analysis of drugs of abuse: can adulterants be detected by sample check test?

scientific article published in January 2017

Fast progression of liver damage in lysosomal acid lipase deficiency

scientific article published on 24 May 2017

Fatty acid binding receptors in intestinal physiology and pathophysiology

scientific article published on December 2010

Fetuin-B inhibiert die frühzeitige Zona Pellucida Härtung und erhält so die Fertilität

Fetuin-B, a liver-derived plasma protein is essential for fertilization

scientific journal article

Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury

scientific article published on 19 January 2020

From proteomic multimarker profiling to interesting proteins: thymosin-β(4) and kininogen-1 as new potential biomarkers for inflammatory hepatic lesions

scientific article

Fructose: A Dietary Sugar in Crosstalk with Microbiota Contributing to the Development and Progression of Non-Alcoholic Liver Disease

scientific article published on 19 September 2017

Functional analyses of the new hepatic stellate cell marker protein CRP2

Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis

scientific article

Funktionelle Interaktion der Chemokine CCL5 (RANTES) und CXCL4 (PF4) im Tiermodell und bei Patienten mit chronischen Lebererkrankungen

Gene polymorphisms in the secretory signal peptide of TGF-β1 affect the cellular synthesis, secretion and processing of TGF-β1 and secretion is modulated by the latent TGF-β binding protein-1 (LTBP-1) and furin protease

article

Genetic Characterization of Rat Hepatic Stellate Cell Line HSC-T6 for In Vitro Cell Line Authentication

scientific article published on 29 May 2022

Genetic and Molecular Characterization of the Immortalized Murine Hepatic Stellate Cell Line GRX

scientific article published on 30 April 2022

Genetic characteristics of the human hepatic stellate cell line LX-2.

scientific article

Genetic characteristics of the human hepatic stellate cell line LX–2

Global analysis of host tissue gene expression in the invasive front of colorectal liver metastases

scientific article published on January 2006

Glucocorticoid-loaded liposomes induce a pro-resolution phenotype in human primary macrophages to support chronic wound healing

scientific article published on 05 April 2018

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

article by Daniel J Klionsky et al published January 2021 in Autophagy

HYPERTENSION: EXPERIMENTAL

Has GnRH a direct role in AMH regulation?

scientific article published on 16 April 2019

Hemochromatosis gene sequence deviations in German patients with porphyria cutanea tarda.

scientific article

Hepatic Fibrogenesis

Hepatic Proteome and Lipid Profiling of Wild Type and Lipocalin-2-Deficient Mice in Experimental Steatosis

Hepatic nephroblastoma overexpressed (NOV/CCN3) in experimental liver fibrosis models

Hepatic recruitment of the inflammatory Gr1+monocyte subset upon liver injury promotes hepatic fibrosis

scientific article published on 01 July 2009

Hepatic stellate cell specific endoglin deletion modulates TGF-β signaling and aggravates liver fibrosis in two experimental models of murine liver injury

Hepatic stellate cells down-regulate pro-apoptotic effector abundance and secretion in mast cells

Hepatitis C diagnostics: clinical evaluation of the HCV-core antigen determination

scientific article published on 14 October 2014

Hepatoprotective and Anti-fibrotic Agents: It's Time to Take the Next Step

scientific article

High Circulating Caspase-Cleaved Keratin 18 Fragments (M30) Indicate Short-Term Mortality in Critically Ill Patients

scientific article published on 08 July 2018

High Prevalence of Sticky Platelet Syndrome in Patients with Infertility and Pregnancy Loss

scientific article published on 28 August 2019

High mobility group box 1 as a biomarker in critically ill patients

article

Human intestinal acyl-CoA synthetase 5 is sensitive to the inhibitor triacsin C.

scientific article published on November 2011

Human mesenchymal stem cells towards non-alcoholic steatohepatitis in an immunodeficient mouse model.

scientific article published on 28 April 2014

Hypoxia Induces Astrocyte-Derived Lipocalin-2 in Ischemic Stroke ⬇️

scientific article published on 13 March 2019

IL-13 as Target to Reduce Cholestasis and Dysbiosis in Abcb4 Knockout Mice

scientific article published on 24 August 2020

ITIH5 induces a shift in TGF-β superfamily signaling involving Endoglin and reduces risk for breast cancer metastasis and tumor death

scientific article published on 21 September 2017

ITIH5 mediates epigenetic reprogramming of breast cancer cells

scientific article published on 23 February 2017

Identification of Pparγ-modulated miRNA hubs that target the fibrotic tumor microenvironment

scientific article published on 23 December 2019

Identification of endoglin in rat hepatic stellate cells: new insights into transforming growth factor beta receptor signaling

scientific journal article

Identification of fibrosis-relevant proteins using DIGE (difference in gel electrophoresis) in different models of hepatic fibrosis.

scientific article published in January 2005

Identification of paraxanthine as the most potent caffeine-derived inhibitor of connective tissue growth factor expression in liver parenchymal cells

Identification of platelet-derived growth factor C as a mediator of both renal fibrosis and hypertension

scientific article published on 28 February 2019

Identification of the N-Acetylcysteine Sensitive Receptor Endoglin in Hepatic Stellate Cells

Identification of the chemokine CXCL9 (MIG) as a genetic modifier of liver fibrosis in patients with hepatitis C

Immortal hepatic stellate cell lines: useful tools to study hepatic stellate cell biology and function?

scientific article published on July 2007

Immune surveillance of liver cancer in non-alcoholic fatty liver disease: excess lipids cause CD4 T-cells loss and promote hepatocellular carcinoma development

scientific article

Immunomodulatory effects of transforming growth factor-β in the liver

scientific article

Impact of soluble Endoglin on TGF-β1 mediated immediate early responses in HepG2 cells

article

In search of early events in the development of chronic kidney disease: the emerging role for lipocalin-2/NGAL

article

In vivo Nachweis apoptotischer Hepatischer Sternzellen als Ursache der antifibrotischen Wirkung von TIMP–1 Antagonisten

Inactivation of Cyclin E1 acts pro-apoptotic and anti-proliferative in primary hepatoma cells and protects from hepatocarcinogenesis in mice

Induction of cell death in activated hepatic stellate cells by targeted gene expression of the thymidine kinase/ganciclovir system

scientific article published in April 2004

Induction of experimental obstructive cholestasis in mice

scientific article published on April 2015

Induction of lipocalin-2 expression in acute and chronic experimental liver injury moderated by pro-inflammatory cytokines interleukin-1β through nuclear factor-κB activation

scientific article published on 16 March 2011

Inflammatory Responses of Astrocytes Are Independent from Lipocalin 2

scientific article published on 21 September 2020

Inhibition of hepatic fibrogenesis by matrix metalloproteinase-9 mutants in mice

scientific article published on March 2006

Inhibitory effect of soluble PDGF-beta receptor in culture-activated hepatic stellate cells.

scientific article published in April 2004

Insulin resistance in liver cirrhosis is not associated with circulating Retinol Binding Protein 4

scholarly article by E Yagmur et al published January 2007 in Zeitschrift fuer Gastroenterologie

Insulin resistance in liver cirrhosis is not associated with circulating retinol-binding protein 4.

scientific article published on 2 March 2007

Interleukin-27 acts on hepatic stellate cells and induces signal transducer and activator of transcription 1-dependent responses

scientific article published on 19 August 2010

Interleukin-27 displays interferon-gamma-like functions in human hepatoma cells and hepatocytes

scientific article

Interleukin-33 in the pathogenesis of liver fibrosis: alarming ILC2 and hepatic stellate cells

scientific article published on 26 December 2016

Intracrine signalling of activin A in hepatocytes upregulates connective tissue growth factor (CTGF/CCN2) expression

scientific article published on 7 April 2008

Intrahepatic TH17/TReg Cells in Homeostasis and Disease-It's All About the Balance

scientific article published on 02 October 2020

Intratumor heterogeneity, variability and plasticity: questioning the current concepts in classification and treatment of hepatocellular carcinoma

scientific article

Investigation of soluble anti-Müllerian hormone receptor type 2 as a biomarker for diagnosis of female fertility disorders

scientific article published on 27 August 2019

Isolation and Culture of Primary Murine Hepatic Stellate Cells

scientific article published in January 2017

Isolation and culture of hepatic stellate cells

scientific article published in January 2005

Isolation and time lapse microscopy of highly pure hepatic stellate cells

scientific article published on 16 July 2015

Isolation of Mature (Peritoneum-Derived) Mast Cells and Immature (Bone Marrow-Derived) Mast Cell Precursors from Mice

scientific article

Ito cells are liver-resident antigen-presenting cells for activating T cell responses

scientific article

It’s not all in the cilium, but on the road to it: Genetic interaction network in polycystic kidney and liver diseases and how trafficking and quality control matter

scientific article published on 28 November 2011

IκB kinaseα/β control biliary homeostasis and hepatocarcinogenesis in mice by phosphorylating the cell-death mediator receptor-interacting protein kinase 1.

scientific article published on 11 July 2016

L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men

scientific article published on 29 April 2020

LCN2 null mice are sensitive to endoplasmic reticulum stress and unfolded protein responses

article

LIM-domain protein CRP2 is upregulated in activated hepatic stellate cells by TGFβ1

LIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) is a novel marker of hepatic stellate cells and binding partner of the protein inhibitor of activated STAT1

scientific article

LIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) is a novel marker of hepatic stellate cells and binding partner of the protein inhibitor of activated STAT1

scientific article (publication date: November 2001)

Laser Ablation Inductively Coupled Plasma Mass Spectrometry in Biomedicine and Clinical Diagnosis

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) in trace metal imaging of experimental and clinical metal disorders

Laser ablation inductively coupled plasma mass spectrometry imaging of metals in experimental and clinical Wilson's disease.

scientific article

Latent TGF-β binding protein-1 deficiency decreases female fertility

scientific article published on 9 December 2016

Learning more about the role of Latent transforming growth factor-β binding protein–1 (LTBP–1) – a knockout approach in mice

LightCycler-analysis of the Transforming Growth Factor-beta1 Codon 25 Gene Polymorphism in German Patients with Chronic Hepatitis C Infection

article

Lipid-induced up-regulation of human acyl-CoA synthetase 5 promotes hepatocellular apoptosis.

scientific article published on 12 May 2010

Lipocalin 2 (LCN2) Expression in Hepatic Malfunction and Therapy

scientific article

Lipocalin 2 (LCN2) in experimental liver injury

Lipocalin 2 (LCN2) in hepatic inflammation

Lipocalin 2 (LCN2)-deficient mice are more prone to hepatic steatosis: LCN2 and mitochondrial and peroxisomal integrity

Lipocalin 2 in the pathogenesis of fatty liver disease and nonalcoholic steatohepatitis

Lipocalin 2 und Perilipin 5 in der Pathogenese der durch Fruktose ausgelösten NAFLD

Lipocalin-2 (LCN2) expression during transdifferentiation of rat hepatic stellate cells and its potential impact on liver fibrogenesis

Lipocalin-2 (LCN2) regulates PLIN5 expression and intracellular lipid droplet formation in the liver

scientific article published on 31 July 2014

Lipocalin-2 (NGAL/LCN2), a "help-me" signal in organ inflammation

scientific article published on 5 June 2015

Lipocalin-2 in Fructose-Induced Fatty Liver Disease

scientific article published on 28 November 2017

Lipopolysaccharide-induced acute phase response: New views on trace metal plasticity in hepatic inflammation

scholarly article published 2018

Lipopolysaccharide-induced inflammatory liver injury in mice.

scientific article published in April 2015

Liver Fibrosis: From Pathogenesis to Novel Therapies

scientific article published on 11 May 2016

Liver fibrosis - pathogenesis and novel therapeutic approaches

scientific article published in January 2010

Liver fibrosis: Which mechanisms matter?

scientific article published on 27 October 2016

Liver function critically determines serum retinol-binding protein 4 (RBP4) levels in patients with chronic liver disease and cirrhosis

scientific article published on 01 November 2008

Liver immunology: new perspectives

scientific article published on December 2014

Liver parenchymal cells lacking Lipocalin 2 (LCN2) are prone to endoplasmic reticulum stress and unfolded protein response

scientific article published on 04 January 2019

Low Myostatin Serum Levels Are Associated with Poor Outcome in Critically Ill Patients

scientific article published on 08 August 2020

MAKERGAUL: an innovative MAK2-based model and software for real-time PCR quantification

scientific article published on 30 October 2013

MALDI-MS analysis reveals reliable results in staging HCV induced fibrogenesis

MALDI-TOF mass spectrometry of serum as a promising diagnostic technique to analyze the severity and progression of fibrogenesis in patients suffering from chronic Hepatitis C infection

MUTANT R122A OF QUAIL CYSTEINE AND GLYCINE-RICH PROTEIN, NMR, MINIMIZED STRUCTURE

Magnetic-Assisted Treatment of Liver Fibrosis

scientific article published on 19 October 2019

Mammalian gamete fusion depends on the inhibition of ovastacin by fetuin-B.

scientific article published on October 2014

Mammalian plasma fetuin-B is a selective inhibitor of ovastacin and meprin metalloproteinases

scientific article published in Scientific Reports

Mast Cells in Liver Fibrogenesis

scientific article published on 13 November 2019

Mast cells inhibit activation and profibrogenic activities of hepatic stellate cells

Maternal Factor V Leiden Mutation Is Associated With HELLP Syndrome in Caucasian Women

Maternal factor V Leiden mutation is associated with HELLP syndrome in Caucasian women

scientific article published in January 2008

Maternale und fetale Thrombophilien (Faktor-V-Leiden-Mutation G1691A; Methylterahydrofolatreduktase-Mutation C677T; Prothrombin-Mutation G20210A) zeigen keine Assoziation zum Auftritt eines HELLP-Syndroms

Mechanisms Underlying Cell Therapy in Liver Fibrosis: An Overview

scientific article published on 29 October 2019

Midregional Proadrenomedullin (MRproADM) Serum Levels in Critically Ill Patients Are Associated with Short-Term and Overall Mortality during a Two-Year Follow-Up

scientific article published on 07 August 2020

Milk Exosomes Prevent Intestinal Inflammation in a Genetic Mouse Model of Ulcerative Colitis: A Pilot Experiment

scientific article published on 20 May 2020

Mining the Age-Dependent Reference Intervals of B Vitamins from Routine Laboratory Test Results

scientific article published on 01 January 2019

Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets

scientific article

Modulation of intracellular TGF-beta signalling by different PDGF isoforms and MEK1/2 in a murine hepatic stellate cell line

Molecular details of BMP-7 signaling in hepatic stellate cells and myofibroblasts

Molecular details on BMP-7 activity on TGF-beta1-mediated CTGF expression in myofibroblasts

Molecular imaging of Cyclin E1 represents an indicator of acute and chronic liver disease

Molecular response of liver sinusoidal endothelial cells on hydrogels

scientific article published on 26 February 2015

More than a serum parameter: Functional relevance of soluble endoglin (solEng)

Mouse models of metabolic liver injury

scientific article published on April 2015

Mutational analysis and NMR spectroscopy of quail cysteine and glycine-rich protein CRP2 reveal an intrinsic segmental flexibility of LIM domains

scientific article

N-Glycosylation of Lipocalin 2 Is Not Required for Secretion or Exosome Targeting.

scientific article published on 25 April 2018

N-acetyl-L-cysteine suppresses TGF-beta signaling at distinct molecular steps: the biochemical and biological efficacy of a multifunctional, antifibrotic drug

scientific article published in October 2005

NLRP3 inflammasome expression in cultured hepatocytes is regulated by nuclear factor-κB (NF-κB)

scholarly article by SG Boaru et al published 16 January 2015 in Zeitschrift fuer Gastroenterologie

NLRP3 inflammasome expression is driven by NF-κB in cultured hepatocytes

scientific article published on 14 February 2015

Neue Therapieoptionen für die Leberfibrose

Non-equivalence of anti-Müllerian hormone automated assays-clinical implications for use as a companion diagnostic for individualised gonadotrophin dosing.

scientific article published on August 2017

Non-invasive diagnosis and assessment of patients with chronic hepatitis C (CHC): The importance of serum proteome profiling with SELDI-TOF-MS – preliminary results

Non-synonymous gene polymorphisms in the secretory signal peptide of human TGF-beta1 affect cellular synthesis but not secretion of TGF-beta1.

scientific article

Novel bioimaging techniques of metals by laser ablation inductively coupled plasma mass spectrometry for diagnosis of fibrotic and cirrhotic liver disorders

scientific article

O145 THE REGULATORY INTERPLAY BETWEEN JNK1 AND JNK2 IS A SINE QUA NON CONDITION AGAINST DRUG-INDUCED LIVER TOXICITY

article

Occult celiac disease prevents penetrance of hemochromatosis

scientific article

Optimization purity of isolated primary liver endothelial cells (LSEC) using adenoviral gene transfer

article

Organ and tissue fibrosis: Molecular signals, cellular mechanisms and translational implications

scientific article published on 30 June 2018

Overexpression of endoglin modulates TGF-β1-signalling pathways in a novel immortalized mouse hepatic stellate cell line

scientific article

Overwhelming high quantities of the matricellular protein CCN1/CYR61 induce ER stress-related cellular apoptosis in hepatic stellate cells

P0285 : Inactivation of cyclin E1 acts pro-apoptotic and anti-proliferative in primary hepatoma cells and protects from hepatocarcinogenesis in mice

P0427 : Platelet-derived growth factor-D intensifies fibrogenesis through upregulation of TIMP-1 and signaling via both platelet-derived growth factor receptor type alpha and beta

P0432 : NLRP3 inflammasome expression is regulated by nuclear factor-kappab(NF-κB)in cultured hepatocytes

scholarly article by S.G. Boaru et al published April 2015 in Journal of Hepatology

P0448 : Benefits of isolating HSC using fluorescence-based cell sorting

P593 ANTIFIBROTIC EFFECTS OF CCN1/CYR61 ARE MEDIATED THROUGH INDUCTION OF REACTIVE OXYGEN SPECIES RESULTING IN PMF AND HSC APOPTOSIS AND ATTENUATED TGF BETA SIGNALLING

PDGF isoform expression in carbon tetrachloride induced chronic liver injury

PDGF-D signaling in portal myofibroblasts and hepatic stellate cells proves identical to PDGF-B via both PDGF receptor type α and β.

scientific article published on 27 March 2015

PLGA-Nanospheres: Delivery tools for the treatment of liver fibrosis

PTGS1 compound heterozygosity impairs gene expression and platelet aggregation and is associated with severe bleeding complications

scientific article published on 5 September 2013

Pathogenese der Leberfibrose: Regulation von hepatischen Sternzellen durch Chemokine

scientific article published on 13 January 2010

Performance of the two new fully automated anti-Müllerian hormone immunoassays compared with the clinical standard assay

scientific article published on 20 June 2015

Perilipin 5 and Lipocalin 2 Expression in Hepatocellular Carcinoma

scientific article published on 19 March 2019

Personalized medicine in hepatitis C: From genome-wide association studies to clinical practice

scientific article published on 01 June 2010

Pharmacological Intervention in Hepatic Stellate Cell Activation and Hepatic Fibrosis

scientific article

Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3-dependent pathways

scientific journal article

Phosphatidylcholine Passes by Paracellular Transport to the Apical Side of the Polarized Biliary Tumor Cell Line Mz-ChA-1

scientific article published on 19 August 2019

Pitfalls in LightCycler diagnosis of the single-nucleotide polymorphism 13.9 kb upstream of the lactase gene that is associated with adult-type hypolactasia

scientific article published on 16 June 2007

Platelet Factor 4 Attenuates Experimental Acute Liver Injury in Mice

Platelet-derived growth factor (PDGF)-C neutralization reveals differential roles of PDGF receptors in liver and kidney fibrosis

scientific article published on 7 November 2012

Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury

scientific article published on 28 July 2008

Platelet-derived growth factor-D intensifies fibrogenesis through upregulation of TIMP-1 expression and signalling through both platelet-derived growth factor receptors type α and β

Platelet-derived growth factor-D modulates extracellular matrix homeostasis and remodeling through TIMP-1 induction and attenuation of MMP-2 and MMP-9 gelatinase activities

scientific article

Portal myofibroblasts are sensitive to CCN-mediated endoplasmic reticulum stress-related apoptosis with potential to attenuate biliary fibrogenesis

scientific article published on 22 July 2018

Potential novel diagnostic applications of laser ablation inductively coupled plasma mass spectrometry in trace metal imaging of hepatic metal disorders

Prevention of hepatic stellate cell activation using JQ1- and atorvastatin-loaded chitosan nanoparticles as a promising approach in therapy of liver fibrosis

scientific article published on 22 November 2018

Primary cultures of glomerular parietal epithelial cells or podocytes with proven origin

scientific article

Primary peritoneal mast cells (PMC) reduce the fibrogenic response of hepatic stellate cells while inducing caspase 3 cleavage and activity

Pro-fibrogenic potential of PDGF-D in liver fibrosis

scientific journal article

Proapoptotic effects of the chemokine, CXCL 10 are mediated by the noncognate receptor TLR4 in hepatocytes

scientific article published on 8 January 2013

Protective effects of Lipocalin-2 (LCN2) in acute and chronic liver injury indicate a novel function in liver homeostasis

Protective effects of lipocalin-2 (LCN2) in acute liver injury suggest a novel function in liver homeostasis.

scientific article

Proteolytisch inaktive MMP-9 Mutanten induzieren Apoptose in Hepatischen Sternzellen

Proteomic profiling in Lipocalin 2 deficient mice under normal and inflammatory conditions

scientific article

Proteomic tissue profiling for the improvement of grading of noninvasive papillary urothelial neoplasia

scientific article

QUAIL CYSTEINE AND GLYCINE-RICH PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE

Quantification of hepatic liver iron overload with laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)

Quantification of liver iron overload disease with laser ablation inductively coupled plasma mass spectrometry

Questioning the challenging role of epithelial-to-mesenchymal transition in liver injury

scientific article published on 01 March 2011

Rapid detection of CSRP2 mRNA in mouse, rat, and human using LightCycler-based quantitative real-time polymerase chain reaction

scientific article published on 01 March 2003

Rapid genotyping of the G534E polymorphism (Marburg I) of the gene encoding the factor VII-activating protease (FSAP) by LightCycler PCR

article

Recent Advances in Practical Methods for Liver Cell Biology: A Short Overview

scientific article published on 16 March 2020

Recent advances in understanding liver fibrosis: bridging basic science and individualized treatment concepts.

scientific article published on 27 June 2018

Recombinant expression, purification, and functional characterisation of connective tissue growth factor and nephroblastoma-overexpressed protein

scientific article

Recombinant fetuin-B protein maintains high fertilization rate in cumulus cell-free mouse oocytes

scientific article published on 12 October 2016

Reconstruction of laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) spatial distribution images in Microsoft Excel 2007

Reference change values of M-protein, free light chain and immunoglobulins in monoclonal gammopathy

scientific article published on 14 September 2019

Regulation and profibrogenic effects of TGF-β1 signaling in mast cells, a cell type contributing to the outcome of hepatic injury

Regulation and prognostic relevance of symmetric dimethylarginine serum concentrations in critical illness and sepsis

scientific article published on 27 June 2013

Regulation von Transaktivierungsmarkern einer etablierten HSC-Linie durch Applikation von Fettsäuren

Relevance of Autophagy in Parenchymal and Non-Parenchymal Liver Cells for Health and Disease

article

Relevance of serum leptin and leptin-receptor concentrations in critically ill patients

scientific article

Relevance of serum sclerostin concentrations in critically ill patients

scientific article published on 22 August 2016

Resveratrol: How Much Wine Do You Have to Drink to Stay Healthy?

scientific article published on 15 July 2016

Resveratrol: Is It Really Good for Liver Health?

article

Role of NOV and CTGF in PDGF and TGF-β signaling in hepatic fibrogenesis

Roles of CCR2 and CCR5 for hepatic macrophage polarization in mice with liver parenchymal cell-specific NEMO deletion

scientific article published on 04 September 2020

Roles of TGF-beta in hepatic fibrosis

scientific article

SLC39A14 deficiency alters manganese homeostasis and excretion resulting in brain manganese accumulation and motor deficits in mice.

scientific article published on 7 February 2018

SP277CONSTITUTIVE ACTIVATION OF PDGFR-β IN RENAL MESENCHYMAL CELLS DRIVES RENAL FIBROSIS

Scavenging endogenous PDGF B-chain by adenovirus-mediated PDGFbetaR-Fc gene transfer potentially inhibits HSC activation and attenuates liver fibrosis

article

Schistosoma mansoni Egg-Secreted Antigens Activate Hepatocellular Carcinoma-Associated Transcription Factors c-Jun and STAT3 in Hamster and Human Hepatocytes

article by Martin Roderfeld et al published 27 July 2018 in Hepatology

Serum proteomic profiling in patients with bladder cancer

scientific article

Severity assessment in mice subjected to carbon tetrachloride

scientific article published on 25 September 2020

Severity of Coronavirus Disease 2019 (COVID-19): Does Surfactant Matter?

scientific article published on 26 August 2020

Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease (NAFLD) With Portal Hypertension in TGR(mREN2)27 Rats

scientific article published on 07 May 2020

Simultaneous monitoring of cerebral metal accumulation in an experimental model of Wilson's disease by laser ablation inductively coupled plasma mass spectrometry

scientific article

Single Cell RNA Sequencing Identifies Subsets of Hepatic Stellate Cells and Myofibroblasts in Liver Fibrosis

scientific article published on 24 May 2019

Small heterodimer partner (SHP) links hepatitis C and liver fibrosis: a small protein on the big stage

scientific article published on 2 June 2015

Software solutions for evaluation and visualization of laser ablation inductively coupled plasma mass spectrometry imaging (LA-ICP-MSI) data: a short overview

scientific article published on 18 February 2019

Soluble Endoglin modulates TGF-β1 mediated signaling in isolated hepatocytes

Solution structure of the carboxyl-terminal LIM domain from quail cysteine-rich protein CRP2

scientific article

Special Issue on "Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis"

scientific article published on 29 April 2020

Standard operating procedures in experimental liver research: thioacetamide model in mice and rats.

scientific article published in April 2015

Standard operating procedures in experimental liver research: time to achieve uniformity

scientific article published in April 2015

Standardization and Normalization of Data from Laser Ablation Inductively Coupled Plasma Mass Spectrometry

Structure and intramodular dynamics of the amino-terminal LIM domain from quail cysteine- and glycine-rich protein CRP2

scientific article

Structure of Cysteine- and Glycine-rich Protein CRP2

scientific article published on 01 September 1998

Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition

Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition

scientific article published on 28 February 2019

Suppression in transformed avian fibroblasts of a gene (CO6) encoding a membrane protein related to mammalian potassium channel regulatory subunits.

scientific article published on March 1997

Suppression in transformed avian fibroblasts of a gene (crp) encoding a cysteine-rich protein containing LIM domains

scientific article

Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity

article

Synergistic effects of Platelet-derived growth factor-BB and Transforming growth factor-β1 on profibrogenic activities in hepatic stellate cells

Systemic antigen cross-presented by liver sinusoidal endothelial cells induces liver-specific CD8 T-cell retention and tolerization

scientific article published in May 2009

TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer.

scientific article published in May 2010

TGF-beta1 does not induce senescence of multipotent mesenchymal stromal cells and has similar effects in early and late passages

scientific article

TGF-β induced upregulation of CRP2 and SRF in activated hepatic stellate cells–Involvement in smooth muscle gene expression during liver fibrogenesis?

article

TGF-β stimulation in human and murine cells reveals commonly affected biological processes and pathways at transcription level

scientific article

TGF-β up-regulates serum response factor in activated hepatic stellate cells

scientific article published on 04 November 2007

TGF-β1 mediated Smad1/Smad5 signalling modulates transdifferentiation of hepatic stellate cells

TGF-β1 modulates LPS-induced NLRP3 inflammasome activity

TIMP-1 überexprimierende Leberzellen zeigen mittels DIGE-Technologie ein verändertes Proteinmuster mit Fibrose-relevanten Proteinen

TNF-α controls Lipocalin-2 expression in PC-3 prostate cancer cells

scientific article published on 23 July 2020

TNFR1 determines progression of chronic liver injury in the IKKγ/Nemo genetic model

scientific article published on 9 August 2013

Targeted disruption of the mouse Csrp2 gene encoding the cysteine- and glycine-rich LIM domain protein CRP2 result in subtle alteration of cardiac ultrastructure

scientific article

Targeting Activated Hepatic Stellate Cells Using Collagen-Binding Chitosan Nanoparticles for siRNA Delivery to Fibrotic Livers

scientific article published on 25 June 2020

Technical and diagnostic performance of a new fully automated immunoassay for the determination of intact fibroblast growth factor 23 (FGF23)

article published in 2018

Technical and diagnostic performance of a new fully automated immunoassay for the determination of intact fibroblast growth factor 23 (FGF23)

Tgf-β and the Smad Pathway in Liver Fibrogenesis

The Bile Acid-Phospholipid Conjugate Ursodeoxycholyl-Lysophosphatidylethanolamide (UDCA-LPE) Disintegrates the Lipid Backbone of Raft Plasma Membrane Domains by the Removal of the Membrane Phospholipase A2

scientific article published on 11 November 2019

The CRP/MLP/TLP family of LIM domain proteins: acting by connecting

scientific article

The CSRP2-Promoter: A Tool for Transcriptional Targeting of Hepatic Stellate Cells During Liver Fibrogenesis?

The CSRP2BP histone acetyltransferase drives smooth muscle gene expression

scientific article

The CYR61/CTGF/NOV (CCN) family members induce endoplasmic reticulum stress and unfolded protein response

The Impact of a Nitric Oxide Synthase Inhibitor (L-NAME) on Ischemia⁻Reperfusion Injury of Cholestatic Livers by Pringle Maneuver and Liver Resection after Bile Duct Ligation in Rats. ⬇️

scientific article published on 29 April 2019

The Influence of Different Fat Sources on Steatohepatitis and Fibrosis Development in the Western Diet Mouse Model of Non-alcoholic Steatohepatitis (NASH)

scientific article published on 25 June 2019

The Inhibitory T Cell Receptors PD1 and 2B4 Are Differentially Regulated on CD4 and CD8 T Cells in a Mouse Model of Non-alcoholic Steatohepatitis

scientific article published on 13 March 2019

The Marburg I variant (G534E) of the factor VII-activating protease determines liver fibrosis in hepatitis C infection by reduced proteolysis of platelet-derived growth factor BB.

scientific article

The N-Acetylcysteine sensitive TGF-β receptor endoglin shows a defined expression pattern in liver cells

The N-acetylcysteine sensitive TGF-β receptor endoglin shows a defined expression pattern in liver cells

The PDGF system and its antagonists in liver fibrosis

scientific article published on 30 October 2015

The Role of Radiologic Modalities in Diagnosing Nonalcoholic Steatohepatitis (NASH) and Fibrosis

The absence of latent transforming growth factor-beta binding protein–1 (LTBP–1) inhibits TGF-beta secretion

The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling.

scientific article published on 31 January 2014

The carbon tetrachloride model in mice

scientific article published on April 2015

The concanavalin A model of acute hepatitis in mice

scientific article published on April 2015

The cysteine- and glycine-rich LIM domain protein CRP2 specifically interacts with a novel human protein (CRP2BP)

scientific article

The cysteine-rich protein family of highly related LIM domain proteins

scientific article

The expression and antigenicity identification of recombinant rat TGF-beta1 in bacteria.

scientific article published on June 2001

The expression of CSRP2 encoding the LIM domain protein CRP2 is mediated by TGF-beta in smooth muscle and hepatic stellate cells

scientific article published on 22 May 2006

The fractalkine receptor CX3CR1 is involved in liver fibrosis due to chronic hepatitis C infection

The fraktalkine receptor CX3CR1 is associated with progression of liver fibrosis in patients with chronic hepatitis C

The genes that underlie fatty liver disease: The harvest has begun

article

The hepatic lipidome: From basic science to clinical translation

scientific article published on 29 June 2020

The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma.

scientific article published on 26 October 2017

The hop constituent xanthohumol exhibits hepatoprotective effects and inhibits the activation of hepatic stellate cells at different levels

scientific article

The impact of TGF-β and S1P on the cellular localization of the LIM domain proteins CRP2 and FHL2 in LX-2 cells

The impact of the reactive oxygen species scavenger N-acetyl-L-cysteine for PDGF-BB signaling in cultured hepatic stellate cells

The interesting case-orphan diseases-double trouble

scientific article published on 01 April 2019

The knockout of latent transforming growth factor-β binding protein–1 (LTBP–1) affects the fibrogenic potential in mice liver

The megalin/gp330 receptor is involved in the capability of hepatic stellate cells to bind and internalize vitamin D binding protein (Gc-globulin)

article published in 2008

The miR-371∼373 Cluster Represses Colon Cancer Initiation and Metastatic Colonization by Inhibiting the TGFBR2/ID1 Signaling Axis

The murine latent transforming growth factor-β binding protein (Ltbp-1) is alternatively spliced, and maps to a region syntenic to human chromosome 2p21–22 ⬇️

scientific article published on April 10, 2003

The nucleic acid binding protein YB-1-controlled expression of CXCL-1 modulates kidney damage in liver fibrosis

scientific article published on 09 November 2019

The platelet-derived chemokine CXCL4 mediates experimental liver fibrosis and is associated with HCV and NASH induced fibrosis

The role of PDGF-D in healthy and fibrotic kidneys.

scientific article

The selective induction of apoptosis in HSC by the targeted thymidine kinase/Ganciclovir system

The serum protein fetuin-b increases in vitro fertilization rate in mice by inhibiting premature zona pellucida hardening

The tightrope of therapeutic suppression of active transforming growth factor-β: high enough to fall deeply?

scientific article published on 01 November 2003

The use of marine-derived bioactive compounds as potential hepatoprotective agents

scientific article

The „accessory“ TGF-β pathway is not obligatory to ALK1 expressing cells

Therapeutic Application of Micellar Solubilized Xanthohumol in a Western-Type Diet-Induced Mouse Model of Obesity, Diabetes and Non-Alcoholic Fatty Liver Disease.

scientific article published on 17 April 2019

Therapeutic Inhibition of Inflammatory Monocyte Recruitment Reduces Steatohepatitis and Liver Fibrosis

scientific article published on 21 September 2017

Therapeutic Targeting of Hepatic Macrophages for the Treatment of Liver Diseases

scientific article published on 03 December 2019

Therapeutic targeting of the mitochondrial reactive oxygen species engine prevents portal hypertension and hepatic fibrogenesis

scientific article published in July 2017

Trace metal imaging in diagnostic of hepatic metal disease

scientific article published on 11 February 2015

Transcriptional Targeting of Activated Hepatic Stellate Cells by Modular Promoter Fragments

Transcriptional activity of Serum Response Factor is mediated by the RhoA/Rho kinase pathway during HSC differentiation and influences expression of Smooth Muscle Cell marker genes

article

Transdifferentiation-dependent expression of distinct C5a-receptors C5R1 and C5L2 in cultured hepatic stellate cells and their response to C5a-ligand

Transdifferenzierungsabhängige Expression von Spleißvarianten des Transkriptionsfaktors „Serum Response Factor“ in aktivierten hepatischen Sternzellen

Transforming Growth Factor-β Gene Polymorphisms in Sarcoidosis Patients With and Without Fibrosis

article

Transforming Growth Factor-β induced Expression of Serum Response Factor in Hepatic Stellate Cells during Liver Fibrogenesis

Transforming growth factor beta 1 gene variants increase transcription and are associated with liver cirrhosis in Chinese

scientific article

Transforming growth factor-beta1 gene polymorphisms are associated with progression of liver fibrosis in Caucasians with chronic hepatitis C infection

scientific article

Transiente Proliferation und Aktivierung Hepatischer Sternzellen im Maus-Modell der Thioacetamid induzierten Fibrose

Transkriptionelles targeting hepatischer Sternzellen durch Einsatz Zell-spezifischer Promotoren in adenoviralen Systemen

Tumor Necrosis Factor-α (TNFα) Stimulates Triple-Negative Breast Cancer Stem Cells to Promote Intratumoral Invasion and Neovasculogenesis in the Liver of a Xenograft Model

scientific article published in 2022

Understanding the Role of Perilipin 5 in Non-Alcoholic Fatty Liver Disease and Its Role in Hepatocellular Carcinoma: A Review of Novel Insights ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2021

Untersuchung von Lipocalin 2 und Perilipin 5 in der Fruktose-induzierten Nichtalkoholischen Fettlebererkrankung

Up-regulated expression of the receptor for advanced glycation end products in cultured rat hepatic stellate cells during transdifferentiation to myofibroblasts

scientific article published on 01 November 2001

Update on hepatic stellate cells: pathogenic role in liver fibrosis and novel isolation techniques

scientific article published on February 2012

Upregulation of human acyl-CoA synthetase 5 in fatty liver degeneration sensitizes for hepatocellular apoptosis

Upregulation of smooth muscle cell markers in activated hepatic stellate cells is mediated by serum response factor

Usage of Mitogen-Activated Protein Kinase Small Molecule Inhibitors: More Than Just Inhibition!

scientific article published on 12 February 2018

Validation of connective tissue growth factor (CTGF/CCN2) and its gene polymorphisms as noninvasive biomarkers for the assessment of liver fibrosis

scientific article published on 20 February 2009

Variable expression of cystatin C in cultured trans-differentiating rat hepatic stellate cells

scientific journal article

Verminderte Transgenexpression nach adenoviralem Gentransfer in experimentell geschädigten Rattenlebern

Visfatin Serum Levels Predict Mortality in Critically Ill Patients

scientific article published on 26 August 2018

Visualization of the therapeutic efficacy of a gene correction approach in Wilson's disease by laser-ablation inductively coupled mass spectrometry

scientific article

Vitamin B1 interpretation: Erroneous higher levels in non-anemic populations

scientific article published on 05 September 2018

What Does the "AKT" Stand for in the Name "AKT Kinase"? Some Historical Comments

scientific article published on 11 August 2020

When sleeping beauty wakes up and jumps into a cancer-minded environment

scientific article published on 01 June 2009

Y-box-binding protein (YB-1) in murine models of hepatic and renal fibrosis

Zinc supplementation augments TGF-β1-dependent regulatory T cell induction

scientific article published on 29 October 2016

[104] FUNCTIONAL AND GENETIC INTERACTION OF THE CHEMOKINES CCL (RANTES) AND CXCL (PF) IN CHRONIC LIVER DISEASES IN MICE AND HUMANS

[247] CIRCULATING RETINOL BINDING PROTEIN 4 IS REDUCED IN LIVER CIRRHOSIS AND NOT ASSOCIATED WITH INSULIN RESISTANCE

scholarly article by E. Yagmur et al published April 2007 in Journal of Hepatology

[453] ASSOCIATION OF CCBP2, A SCAVENGER RECEPTOR FOR INFLAMMATORY CC CHEMOKINES, WITH LIVER INFLAMMATION IN MICE AND HUMANS

miR-133a mediates TGF-β-dependent derepression of collagen synthesis in hepatic stellate cells during liver fibrosis

scientific article published on 23 November 2012

α2-Adrenergic Receptor in Liver Fibrosis: Implications for the Adrenoblocker Mesedin

scientific article published on 18 February 2020

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