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List of works by Lai Guan Ng

"Cloaking" on Time: A Cover-Up Act by Resident Tissue Macrophages

scientific article published on 01 April 2019

3-Dimensional Optical Clearing and Imaging of Pruritic Atopic Dermatitis and Psoriasis Skin Reveals Downregulation of Epidermal Innervation

scientific article published on 22 November 2018

A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment

scientific article published on August 2017

A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart

scientific article published on 09 September 2020

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection

scientific article published on 29 January 2019

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection

scientific article published on 01 November 2019

A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils

scientific article published on 27 March 2019

A quantitative approach to histopathological dissection of elastin-related disorders using multiphoton microscopy.

scientific article published in October 2013

A small-molecule FRET reporter for the real-time visualization of cell-surface proteolytic enzyme functions.

scientific article

A three-dimensional atlas of human dermal leukocytes, lymphatics, and blood vessels

scientific article

Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages

scientific article

Anti-Allergic Inflammatory Activity of Interleukin-37 Is Mediated by Novel Signaling Cascades in Human Eosinophils.

scientific article published on 22 June 2018

Author Correction: Lung endothelial cell antigen cross-presentation to CD8+T cells drives malaria-associated lung injury

scientific article published on 04 November 2019

B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation.

scientific article

BAFF augments certain Th1-associated inflammatory responses.

scientific article published in May 2005

Biocompatible Green and Red Fluorescent Organic Dots with Remarkably Large Two-Photon Action Cross Sections for Targeted Cellular Imaging and Real-Time Intravital Blood Vascular Visualization

scientific article published on 2 July 2015

C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages

scientific article

CD41 is a reliable identification and activation marker for murine basophils in the steady state and during helminth and malarial infections

scientific article published on 10 April 2014

CD44 mediates successful interstitial navigation by killer T cells and enables efficient antitumor immunity

scientific article

CD8 T cells regulate allergic contact dermatitis by modulating CCR2-dependent TNF/iNOS-expressing Ly6C+ CD11b+ monocytic cells

scientific article published on 23 September 2013

CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses.

scientific article published on 10 October 2016

Capturing the Fantastic Voyage of Monocytes Through Time and Space

scientific article published on 16 April 2019

Co-option of Neutrophil Fates by Tissue Environments

scientific article published on 20 October 2020

Combinatorial Single-Cell Analyses of Granulocyte-Monocyte Progenitor Heterogeneity Reveals an Early Uni-potent Neutrophil Progenitor

scientific article published on 22 June 2020

Cutaneous immunosurveillance by self-renewing dermal gammadelta T cells

scientific article

DC mobilization from the skin requires docking to immobilized CCL21 on lymphatic endothelium and intralymphatic crawling

scientific article

Deciphering human macrophage development at single-cell resolution

scientific article published on 20 May 2020

Deterministic reprogramming of neutrophils within tumors

scientific article published on 11 January 2024

Development of nephritis but not sialadenitis in autoimmune-prone BAFF transgenic mice lacking marginal zone B cells.

scientific article published in September 2006

Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions

scientific article published in February 2018

Dimensionality reduction for visualizing single-cell data using UMAP

scientific article published on 03 December 2018

Dual modal ultra-bright nanodots with aggregation-induced emission and gadolinium-chelation for vascular integrity and leakage detection

scientific article published on 20 October 2017

Dynamic Imaging of CD8(+) T cells and dendritic cells during infection with Toxoplasma gondii

scientific article

Efficient aortic lymphatic drainage is necessary for atherosclerosis regression induced by ezetimibe

scientific article published on 11 December 2020

Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19

scientific article published on 05 August 2020

Evaluation of UMAP as an alternative to t-SNE for single-cell data

scholarly article published 10 April 2018

Ezh2 Controls Skin Tolerance through Distinct Mechanisms in Different Subsets of Skin Dendritic Cells

scientific article published on 14 November 2018

Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells

scientific article published on 01 September 2019

Fate mapping analysis reveals that adult microglia derive from primitive macrophages

scientific article (publication date: 5 November 2010)

Glycopeptide antibiotic analogs for selective inactivation and two-photon imaging of vancomycin-resistant strains.

scientific article published on 8 March 2016

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

scientific article published on 01 October 2019

Heterogeneity of neutrophils

scientific article published on 01 April 2019

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen

scholarly article by Hwee Ying Lim et al published August 2018 in Immunity

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen

scientific article published on 01 December 2018

IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses

scientific article published on May 2013

Identification of a novel lymphoid population in the murine epidermis

scientific article published on 30 July 2015

Illuminating the covert mission of mononuclear phagocytes in their regional niches

scientific article

Imaging of Inflammatory Responses in the Mouse Ear Skin

scientific article published in January 2018

In silico modeling of cancer cell dissemination and metastasis.

scientific article published in May 2013

In vivo imaging of cutaneous T-cell lymphoma migration to the skin

scientific article published on 24 March 2009

Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function

scientific article published on 01 February 2020

Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.

scientific article published on July 2017

Inducing Ischemia-reperfusion Injury in the Mouse Ear Skin for Intravital Multiphoton Imaging of Immune Responses

scientific article published on 22 December 2016

Intravital multiphoton imaging of immune responses in the mouse ear skin

article

Intravital multiphoton imaging of mouse tibialis anterior muscle

scientific article

Langerhans cells are precommitted to immune tolerance induction

scientific article published on 17 October 2011

Lights, camera, and action: vertebrate skin sets the stage for immune cell interaction with arthropod-vectored pathogens

scientific article published in 2013

Lung endothelial cell antigen cross-presentation to CD8+T cells drives malaria-associated lung injury

scientific article published on 18 September 2019

Micelle/Silica Co-protected Conjugated Polymer Nanoparticles for Two-Photon Excited Brain Vascular Imaging

Multi-modal image cytometry approach - From dynamic to whole organ imaging

scientific article published on 02 July 2019

NIR-II-Excited Intravital Two-Photon Microscopy Distinguishes Deep Cerebral and Tumor Vasculatures with an Ultrabright NIR-I AIE Luminogen

scientific article published on 15 September 2019

Nanocrystallization: A Unique Approach to Yield Bright Organic Nanocrystals for Biological Applications

scientific article published on 2 November 2016

Nanostring Analysis of Skin Biopsies from Patients with Henoch-Schönlein Purpura Reveals Genes Associated with Pathology and Heterogeneity in the Disease Process

article

Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow

scientific article

Neutrophil: A mobile fertilizer

scientific article published on 19 December 2018

Neutrophils Self-Regulate Immune Complex-Mediated Cutaneous Inflammation through CXCL2.

scientific article published on February 2016

Neutrophils contribute to inflammatory lymphangiogenesis by increasing VEGF-A bioavailability and secreting VEGF-D.

scientific article

Neutrophils instruct homeostatic and pathological states in naive tissues

scientific article published on 03 October 2018

Organic nanoparticles with ultrahigh quantum yield and aggregation-induced emission characteristics for cellular imaging and real-time two-photon lung vasculature imaging

scientific article published on 23 April 2018

PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function

scientific article published on 01 June 2019

Peeking into the secret life of neutrophils.

scientific article published on September 2012

Perivascular leukocyte clusters are essential for efficient activation of effector T cells in the skin

scientific article published on 21 September 2014

Perivascular macrophages mediate neutrophil recruitment during bacterial skin infection

scientific article

Plasmodium vivax: restricted tropism and rapid remodeling of CD71-positive reticulocytes

scientific article

Polymeric nanorods with aggregation-induced emission characteristics for enhanced cancer targeting and imaging

scientific article published on 01 March 2018

Polymerization-Enhanced Two-Photon Photosensitization for Precise Photodynamic Therapy

scientific article published on 18 February 2019

Random migration precedes stable target cell interactions of tumor-infiltrating T cells.

scientific article

Real-Time Imaging of Dendritic Cell Responses to Sterile Tissue Injury

article

Red Emissive Biocompatible Nanoparticles from Tetraphenylethene-Decorated BODIPY Luminogens for Two-Photon Excited Fluorescence Cellular Imaging and Mouse Brain Blood Vascular Visualization

scholarly article by Zujin Zhao et al published 21 October 2013 in Particle & Particle Systems Characterization

Reprint of "Multi-modal image cytometry approach - From dynamic to whole organ imaging"

scientific article published on 10 March 2020

Research Techniques Made Simple: Optical Clearing and Three-Dimensional Volumetric Imaging of Skin Biopsies

scientific article published on 01 July 2020

Resident macrophages restrain pathological adipose tissue remodeling and protect vascular integrity in obese mice

scientific article published on 01 July 2021

Reverse-engineering flow-cytometry gating strategies for phenotypic labelling and high-performance cell sorting

scientific article published on 01 January 2019

Rodent Plasmodium-infected red blood cells: imaging their fates and interactions within their hosts

scientific article published on 25 July 2013

Silica shelled and block copolymer encapsulated red-emissive AIE nanoparticles with 50% quantum yield for two-photon excited vascular imaging

scientific article published on 27 July 2015

Streamlining volumetric multi-channel image cytometry using hue-saturation-brightness-based surface creation

scientific article published on 06 September 2018

TNF Deficiency Fails to Protect BAFF Transgenic Mice against Autoimmunity and Reveals a Predisposition to B Cell Lymphoma

scientific article published on 01 January 2004

Targeted induction of antigen expression within dendritic cells modulates antigen-specific immunity afforded by recombinant BCG

scientific article published on 04 January 2011

The BAFF/APRIL system: life beyond B lymphocytes.

scientific article

The gut microbiota influences blood-brain barrier permeability in mice

scientific article

The impact of ischemia-reperfusion injuries on skin resident murine dendritic cells.

scientific article published on 6 March 2018

The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin

scientific article

Transitional premonocytes emerge in the periphery for host defense against bacterial infections

scientific article published on 04 March 2022

Tumor stroma and chemokines control T-cell migration into melanoma following Temozolomide treatment.

scientific article published on 25 February 2015

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

scientific article

Two-photon imaging of effector T-cell behavior: lessons from a tumor model.

scientific article published on February 2008

Ultrabright organic dots with aggregation-induced emission characteristics for real-time two-photon intravital vasculature imaging

scientific article published on 19 August 2013

Understanding the murine cutaneous dendritic cell network to improve intradermal vaccination strategies.

scientific article published on January 2012

Visualization of bone marrow monocyte mobilization using Cx3cr1gfp/+Flt3L-/- reporter mouse by multiphoton intravital microscopy.

scientific article published on 16 December 2014

Visualizing dendritic cell migration within the skin

scientific article

Visualizing the neutrophil response to sterile tissue injury in mouse dermis reveals a three-phase cascade of events.

scientific article published on 23 June 2011

Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19

scientific article published on 16 October 2020

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