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List of works by Thorsten Hugel

A Multicolor Single-Molecule FRET Approach to Study Protein Dynamics and Interactions Simultaneously

scientific article published on 10 October 2016

A blind benchmark of analysis tools to infer kinetic rate constants from single-molecule FRET trajectories

scientific article published in 2022

AFM Imaging Suggests Receptor-Free Penetration of Lipid Bilayers by Toxins

scientific article published on 02 January 2019

Adhesion property profiles of supported thin polymer films.

scientific article published on 20 June 2013

Adsorption mechanism and valency of catechol-functionalized hyperbranched polyglycerols.

scientific article published on 18 May 2015

Adsorption mechanism of polypeptides and their location at hydrophobic interfaces.

scientific article published in November 2009

Aging of hydrogenated and oxidized diamond

scientific article published on 01 January 2010

Atomic force microscopy spring constant determination in viscous liquids

scientific article published in March 2009

Bio-inspired novel design principles for artificial molecular motors.

scientific article published on 16 July 2010

Comparison of friction and wear of articular cartilage on different length scales

scientific article published on 7 August 2015

Controlling protein function by fine-tuning conformational flexibility

scientific article published on 22 July 2020

Controlling the structure of proteins at surfaces.

scientific article

Cooperative Nucleotide Binding in Hsp90 and Its Regulation by Aha1.

scientific article

Dynamics of heat shock protein 90 C-terminal dimerization is an important part of its conformational cycle

scientific article

Effect of Molecular Architecture on Single Polymer Adhesion

scientific article published on 08 April 2014

Effects of inhibitors on Hsp90's conformational dynamics, cochaperone and client interactions

scientific article published on 20 April 2018

Efficient use of single molecule time traces to resolve kinetic rates, models and uncertainties.

scientific article published in March 2018

Elastin: a representative ideal protein elastomer.

scientific article

Experimental test of connector rotation during DNA packaging into bacteriophage phi29 capsids

scientific article

FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices

scientific article

Folding and Domain Interactions of Three Orthologs of Hsp90 Studied by Single-Molecule Force Spectroscopy

scientific article published on 18 December 2017

Folding and assembly of the large molecular machine Hsp90 studied in single-molecule experiments.

scientific article published on 19 January 2016

Four-colour FRET reveals directionality in the Hsp90 multicomponent machinery

scientific article

From a ratchet mechanism to random fluctuations evolution of Hsp90's mechanochemical cycle

scientific article published on 06 August 2012

From biological towards artificial molecular motors

scientific article published on August 2008

Heat shock protein 90's mechanochemical cycle is dominated by thermal fluctuations

scientific article published on 19 December 2011

Highly hydrated deformable polyethylene glycol-tethered lipid bilayers.

scientific article published on 30 July 2014

Highly stretched single polymers: atomic-force-microscope experiments versus ab-initio theory

scientific article published on 31 January 2005

Hydration Effects Turn a Highly Stretched Polymer from an Entropic into an Energetic Spring.

scientific article published on 15 December 2016

Hydrophobic and Hofmeister effects on the adhesion of spider silk proteins onto solid substrates: an AFM-based single-molecule study

scientific article published on 28 November 2007

Investigating single molecule adhesion by atomic force spectroscopy

scientific article

Kinetics of Transient Protein Complexes Determined via Diffusion-Independent Microfluidic Mixing and Fluorescence Stoichiometry

article

Measuring the interaction between ions, biopolymers and interfaces – one polymer at a time

scientific article published on 01 January 2013

Mechanism of Reversible Peptide-Bilayer Attachment: Combined Simulation and Experimental Single-Molecule Study

scientific article published on 30 December 2015

Multivalent anchored and crosslinked hyperbranched polyglycerol monolayers as antifouling coating for titanium oxide surfaces.

scientific article published on 10 August 2014

Nanoscale friction mechanisms at solid-liquid interfaces

scientific article published on 10 May 2013

Nucleotides and substrates trigger the dynamics of the Toc34 GTPase homodimer involved in chloroplast preprotein translocation

scientific article

On the relationship between peptide adsorption resistance and surface contact angle: a combined experimental and simulation single-molecule study

scientific article published on 19 November 2012

Opposing Temperature Dependence of the Stretching Response of Single PEG and PNiPAM Polymers

scientific article published on 15 July 2019

Peptide adsorption on a hydrophobic surface results from an interplay of solvation, surface, and intrapeptide forces.

scholarly article

Peptide desorption kinetics from single molecule force spectroscopy studies

scientific article published on 03 January 2014

Phase contrast and DIC illumination for AFM hybrids

scientific article published on 01 October 2005

Polymer Carpets

scientific article published on 01 August 2010

Polymer adhesion at the solid-liquid interface probed by a single-molecule force sensor

scientific article published on 01 December 2009

Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study

scientific article published on 31 August 2018

Probing solid surfaces with single polymers

scientific article published on 01 September 2003

Publisher Correction: Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study

scholarly article by Björn Hellenkamp published in October 2018

Pulling a single polymer molecule off a substrate reveals the binding thermodynamics of cosolutes

scientific article published in June 2010

Regulatory Posttranslational Modifications in Hsp90 Can Be Compensated by Cochaperone Aha1

scientific article published on March 18, 2011

Single lipid extraction: the anchoring strength of cholesterol in liquid-ordered and liquid-disordered phases

scientific article

Single molecule force measurements delineate salt, pH and surface effects on biopolymer adhesion

scientific article published in July 2009

Single-Molecule Analysis beyond Dwell Times: Demonstration and Assessment in and out of Equilibrium

scientific article

Single-molecule optomechanical cycle

scientific article

The Hsp90 ensemble: coordinated Hsp90-cochaperone complexes regulate diverse cellular processes

scientific article published on 01 December 2014

The charged linker of the molecular chaperone Hsp90 modulates domain contacts and biological function

scientific article

The effect of temperature on single-polypeptide adsorption

scientific article published on 31 January 2012

The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis

scientific article published on 22 February 2009

The nanomechanical properties of lipid membranes are significantly influenced by the presence of ethanol

scientific article published on March 2013

The structure and mechanical properties of articular cartilage are highly resilient towards transient dehydration

scientific article published on 29 September 2015