Search filters

List of works by Michiyuki Matsuda

A FRET Biosensor for ROCK Based on a Consensus Substrate Sequence Identified by KISS Technology.

scientific article

A FRET-based probe for epidermal growth factor receptor bound non-covalently to a pair of synthetic amphipathic helixes.

scientific article published on 7 April 2005

A Highly Sensitive FRET Biosensor for AMPK Exhibits Heterogeneous AMPK Responses among Cells and Organs

scientific article published in November 2017

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

scientific article

A clathrin-dependent pathway leads to KRas signaling on late endosomes en route to lysosomes.

scientific article published on 16 March 2009

A family of cAMP-binding proteins that directly activate Rap1

scientific article

A genetically encoded Förster resonance energy transfer biosensor for two-photon excitation microscopy.

scientific article published on 23 February 2011

A glycoprotein in the plasma membrane matrix as a major potential substrate of p60v-src

scientific article published on February 1990

A mammalian two-hybrid screening system for inhibitors of interaction between HIV Nef and the cellular tyrosine kinase Hck.

scientific article

A novel role of nectins in inhibition of the E-cadherin-induced activation of Rac and formation of cell-cell adherens junctions.

scientific article

A pair of fluorescent resonance energy transfer-based probes for tyrosine phosphorylation of the CrkII adaptor protein in vivo.

scientific article published on 13 June 2001

A quantitative model of ERK MAP kinase phosphorylation in crowded media

scientific article published on January 2013

Activation of R-Ras by Ras-Guanine Nucleotide-releasing Factor ⬇️

scientific article published on July 25, 1997

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

scientific article

Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells

scientific article

Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i)

scientific article

Activity of Rho-family GTPases during cell division as visualized with FRET-based probes

scientific article

Adaptor protein Crk is required for ephrin-B1-induced membrane ruffling and focal complex assembly of human aortic endothelial cells.

scientific article

Altered G1 signaling order and commitment point in cells proliferating without CDK4/6 activity

scientific article published on 20 October 2020

An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor-stimulated PC12 cells

scientific journal article

An infectious DNA clone of HIV type 1 subtype C.

scientific article

Analysis of the spatiotemporal activation of rho GTPases using Raichu probes.

scientific article published in January 2006

Both the SH2 and SH3 domains of human CRK protein are required for neuronal differentiation of PC12 cells

scientific article

CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells

scientific article

Cancer-specific mutations in p53 induce the translation of Δ160p53 promoting tumorigenesis

scientific article

Cdc42 and Rac small G proteins activated by trans-interactions of nectins are involved in activation of c-Jun N-terminal kinase, but not in association of nectins and cadherin to form adherens junctions, in fibroblasts.

scientific article published on May 2003

Cdc42 mediates Bmp-induced sprouting angiogenesis through Fmnl3-driven assembly of endothelial filopodia in zebrafish.

scientific article published in January 2015

Cell Density-Dependent Increase in Tyrosine-Monophosphorylated ERK2 in MDCK Cells Expressing Active Ras or Raf.

scientific article

Cell cycle-dependent Rho GTPase activity dynamically regulates cancer cell motility and invasion in vivo

scientific article

Cell type-specific regulation of RhoA activity during cytokinesis.

scientific article published on 12 August 2004

Chimaerin suppresses Rac1 activation at the apical membrane to maintain the cyst structure

scientific article

Chromosomal mapping of the gene encoding DOCK180, a major Crk-binding protein, to 10q26.13-q26.3 by fluorescence in situ hybridization

scientific article

Circuit-dependent striatal PKA and ERK signaling underlies rapid behavioral shift in mating reaction of male mice

scientific article

Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor.

scientific article

Constitutive association of EGF receptor with the CrkII-23 mutant that inhibits transformation of NRK cells by EGF and TGF-beta

scientific article

Crk activation of JNK via C3G and R-Ras

scientific journal article

Cytoplasmic tubular inclusion in ganglioneuroma

scientific article published on 01 January 1984

DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane

scientific article

Development of a FRET biosensor with high specificity for Akt.

scientific article

Development of an optimized backbone of FRET biosensors for kinases and GTPases

scientific article published on 5 October 2011

Differential interaction of CrkII adaptor protein with platelet-derived growth factor alpha- and beta-receptors is determined by its internal tyrosine phosphorylation

scientific article

Distinct predictive performance of Rac1 and Cdc42 in cell migration

scientific article

Dynamic ERK signaling regulation in intestinal tumorigenesis

scientific article published on 11 September 2018

Dynamics of the Ras/ERK MAPK Cascade as Monitored by Fluorescent Probes

scientific article published in Journal of Biological Chemistry

ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization

scientific article published on 27 May 2020

Efficient synthesis of phycocyanobilin in mammalian cells for optogenetic control of cell signaling

scientific article

Emerging components of the Crk oncogene product: the first identified adaptor protein

scientific article

Endogenous tenascin-C enhances glioblastoma invasion with reactive change of surrounding brain tissue.

scientific article

Enhancement of Guanine-Nucleotide Exchange Activity of C3G for Rap1 by the Expression of Crk, CrkL, and Grb2 ⬇️

scientific article published in Journal of Biological Chemistry

Epidermal growth factor-dependent dissociation of CrkII proto-oncogene product from the epidermal growth factor receptor in human glioma cells.

scientific article

Establishment of a MAGI-derived indicator cell line that detects the Nef enhancement of HIV-1 infectivity with high sensitivity.

scientific article published in September 2001

Evidence That DOCK180 Up-regulates Signals from the CrkII-p130Cas Complex ⬇️

scientific article published on September 18, 1998

Experimental pathology by intravital microscopy and genetically encoded fluorescent biosensors

scientific article published on 08 April 2020

FRET imaging and statistical signal processing reveal positive and negative feedback loops regulating the morphology of randomly migrating HT-1080 cells.

scientific article

FRET imaging in nerve growth cones reveals a high level of RhoA activity within the peripheral domain

scientific article published on 01 October 2005

FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics

scientific article published on 09 September 2019

Fluctuation of Rac1 activity is associated with the phenotypic and transcriptional heterogeneity of glioma cells

scientific article published on 12 February 2014

Fluorescence (Förster) resonance energy transfer imaging of oncogene activity in living cells

scientific article

Fluorescence resonance energy transfer based quantitative analysis of feedforward and feedback loops in epidermal growth factor receptor signaling and the sensitivity to molecular targeting drugs

scientific article published on 9 June 2014

Fluorescence resonance energy transfer imaging of cell signaling from in vitro to in vivo: basis of biosensor construction, live imaging, and image processing

scientific article published on 07 February 2013

GDNF and endothelin 3 regulate migration of enteric neural crest-derived cells via protein kinase A and Rac1.

scientific article published on March 2013

GTP hydrolysis by the Rho family GTPase TC10 promotes exocytic vesicle fusion.

scientific article

Genetic characterization of JC virus Tokyo-1 strain, a variant oncogenic in rodents

scientific article

Genetically Encoded Tools for Optical Dissection of the Mammalian Cell Cycle.

scientific article published on 25 October 2017

Heterogeneity in ERK activity as visualized by in vivo FRET imaging of mammary tumor cells developed in MMTV-Neu mice.

scientific article published on 17 March 2014

Heterogeneity of phosphatidic acid levels and distribution at the plasma membrane in living cells as visualized by a Föster resonance energy transfer (FRET) biosensor

scientific article

Host range bias of the JC virus mutant enhancer with DNA rearrangement

scientific article published in May 1989

Human Mena associates with Rac1 small GTPase in glioblastoma cell lines

scientific article

Human immunodeficiency virus type 1 reverse transcriptase: enhancement of activity by interaction with cellular topoisomerase I.

scientific article

Identification of Aging-Associated Gene Expression Signatures That Precede Intestinal Tumorigenesis.

scientific article

Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

scientific article

Identification of domains of the v-crk oncogene product sufficient for association with phosphotyrosine-containing proteins

scientific article

In Vivo FRET Imaging of Tumor Endothelial Cells Highlights a Role of Low PKA Activity in Vascular Hyperpermeability.

scientific article published on 3 August 2016

In vivo fluorescence resonance energy transfer imaging reveals differential activation of Rho-family GTPases in glioblastoma cell invasion

scientific article

In vivo imaging of signal transduction cascades with probes based on Förster Resonance Energy Transfer (FRET).

scientific article

In vivo imaging reveals PKA regulation of ERK activity during neutrophil recruitment to inflamed intestines

scientific article

Inefficient enhancement of viral infectivity and CD4 downregulation by human immunodeficiency virus type 1 Nef from Japanese long-term nonprogressors

scientific article

Infectious DNA clone of HIV type 1 A/G recombinant (CRF02_AG) replicable in peripheral blood mononuclear cells

scientific article published in July 2001

Insufficient ability of Rac1b to perturb cystogenesis ⬇️

scientific article published on January 1, 2013

Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.

scientific article

Interaction between the amino-terminal SH3 domain of CRK and its natural target proteins

scientific article

Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin.

scientific article

Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

scientific journal article

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction

scientific article

Intravital Förster resonance energy transfer imaging reveals osteopontin-mediated polymorphonuclear leukocyte activation by tumor cell emboli

scientific article

Intravital imaging of mouse urothelium reveals activation of extracellular signal-regulated kinase by stretch-induced intravesical release of ATP

scientific article

Intravital imaging reveals cell cycle-dependent myogenic cell migration during muscle regeneration

scientific article published on 01 November 2020

Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling

scientific article

Involvement of the c-Src-Crk-C3G-Rap1 signaling in the nectin-induced activation of Cdc42 and formation of adherens junctions.

scientific article published on 25 October 2004

Lateral propagation of EGF signaling after local stimulation is dependent on receptor density.

scientific article

Live Imaging of Protein Kinase Activities in Transgenic Mice Expressing FRET Biosensors

scientific article published on 24 January 2012

Live imaging of extracellular signal-regulated kinase and protein kinase A activities during thrombus formation in mice expressing biosensors based on Förster resonance energy transfer.

scientific article

Live imaging of transgenic mice expressing FRET biosensors

scientific article published in January 2013

Mapping of the human C3G gene coding a guanine nucleotide releasing protein for Ras family to 9q34.3 by fluorescence in situ hybridization.

scientific article

Mechanism and role of localized activation of Rho-family GTPases in growth factor-stimulated fibroblasts and neuronal cells.

scientific article

Mechanism of the spatio-temporal regulation of Ras and Rap1.

scientific article

Membrane recruitment of DOCK180 by binding to PtdIns(3,4,5)P3

scientific article

Monitoring spatio-temporal regulation of Ras and Rho GTPase with GFP-based FRET probes.

scientific article published in October 2005

Multiple decisive phosphorylation sites for the negative feedback regulation of SOS1 via ERK.

scientific article published on 19 August 2010

Multiplexed Fluorescence Imaging of ERK and Akt Activities and Cell-cycle Progression.

scientific article

Non-adherent cell-specific expression of DOCK2, a member of the human CDM-family proteins

scientific article

Novel function of Chat in controlling cell adhesion via Cas-Crk-C3G-pathway-mediated Rap1 activation.

scientific article published on December 2002

On the Synchrony of Morphological and Molecular Signaling Events in Cell Migration

Osteopontin in Spontaneous Germinal Centers Inhibits Apoptotic Cell Engulfment and Promotes Anti-Nuclear Antibody Production in Lupus-Prone Mice

scientific article

PKA modulation of Rac in neuronal cells

scientific article published on 14 October 2014

Palmitoylated Ras proteins traffic through recycling endosomes to the plasma membrane during exocytosis.

scientific article

Phosphorylation and activation of the Rac1 and Cdc42 GEF Asef in A431 cells stimulated by EGF.

scientific article published on 24 July 2008

Phosphorylation of CrkII adaptor protein at tyrosine 221 by epidermal growth factor receptor

scientific article

Phosphorylation of STEF/Tiam2 by protein kinase A is critical for Rac1 activation and neurite outgrowth in dibutyryl cAMP-treated PC12D cells

scientific article

Processive phosphorylation of ERK MAP kinase in mammalian cells

scientific article

Propagating Wave of ERK Activation Orients Collective Cell Migration.

scientific article published in November 2017

Purification and characterization of Heteroscorpine-1 (HS-1) toxin from Heterometrus laoticus scorpion venom.

scientific article

Quantification of local morphodynamics and local GTPase activity by edge evolution tracking

scientific article

Quantitative analysis of recombination between YFP and CFP genes of FRET biosensors introduced by lentiviral or retroviral gene transfer.

scientific article published on 20 August 2015

Quantitative in vivo fluorescence cross-correlation analyses highlight the importance of competitive effects in the regulation of protein-protein interactions

scientific article

R-Ras regulates exocytosis by Rgl2/Rlf-mediated activation of RalA on endosomes.

scientific article

Rap2 as a slowly responding molecular switch in the Rap1 signaling cascade.

scientific article

Ras and calcium signaling pathways converge at Raf1 via the Shoc2 scaffold protein

scientific article

Ras binding opens c-Raf to expose the docking site for mitogen-activated protein kinase kinase.

scientific article

Real-time fluorescent resonance energy transfer analysis to monitor drug resistance in chronic myelogenous leukemia

scientific article

Regulation of RalA GTPase by phosphatidylinositol 3-kinase as visualized by FRET probes

scientific article published on 01 November 2006

Regulation of focal adhesion and cell migration by ANKRD28-DOCK180 interaction

scientific article

Requirement of Nef for HIV-1 infectivity is biased by the expression levels of Env in the virus-producing cells and CD4 in the target cells ⬇️

scientific article published on January 1, 2001

Retrograde ERK activation waves drive base-to-apex multicellular flow in murine cochlear duct morphogenesis

scientific article published in 2021

Rhodopsin-mediated light-off-induced protein kinase A activation in mouse rod photoreceptor cells

scientific article published on 12 October 2020

Role of Crk oncogene product in physiologic signaling.

scientific article

Role of PKA signaling in D2 receptor-expressing neurons in the core of the nucleus accumbens in aversive learning

scientific article

SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility

scientific article

STAT3 noncell-autonomously controls planar cell polarity during zebrafish convergence and extension.

scientific article published on September 2004

Spatio-temporal images of growth-factor-induced activation of Ras and Rap1.

scientific article published in June 2001

Spatiotemporal regulation of small GTPases as revealed by probes based on the principle of Förster Resonance Energy Transfer (FRET): Implications for signaling and pharmacology

scientific article published on January 2011

Spatiotemporal regulation of the Pak1 kinase

scientific article

Sphingosine 1-phosphate induces membrane ruffling and increases motility of human umbilical vein endothelial cells via vascular endothelial growth factor receptor and CrkII

scientific article (publication date: 28 June 2002)

Stable expression of FRET biosensors: a new light in cancer research

scientific article

Stalling interkinetic nuclear migration in curved pseudostratified epithelium of developing cochlea

scientific article published in 2021

Stochastic ERK activation induced by noise and cell-to-cell propagation regulates cell density-dependent proliferation

scientific article published on 17 October 2013

Structure of 85 kDa subunit of human phosphatidylinositol 3-kinase analyzed by using monoclonal antibodies

scientific article

Suppression of Rac1 activity at the apical membrane of MDCK cells is essential for cyst structure maintenance.

scientific article published on March 2012

Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway.

scientific article

Syndecan 4 regulates FGFR1 signaling in endothelial cells by directing macropinocytosis

scientific article published on 08 May 2012

The DHR1 domain of DOCK180 binds to SNX5 and regulates cation-independent mannose 6-phosphate receptor transport

scientific article

The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src

scientific article

The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway

scientific article

The amino-terminal B-Raf-specific region mediates calcium-dependent homo- and hetero-dimerization of Raf.

scientific article

The cellular kinase binding motifs (PxxP and RR) in human immunodeficiency virus type 1 Nef protein are dispensable for producer-cell-dependent enhancement of viral entry.

scientific article

The scaffold protein Shoc2/SUR-8 accelerates the interaction of Ras and Raf.

scientific article

Two New FRET Imaging Measures: Linearly Proportional to and Highly Contrasting the Fraction of Active Molecules

scientific article

Two species of human CRK cDNA encode proteins with distinct biological activities

scientific article

Visualization of Protein Kinase Activities in Living Cells

scholarly article by Kazuhiro Aoki et al published 2012 in Neuromethods

Visualization of Signaling Molecules During Neutrophil Recruitment in Transgenic Mice Expressing FRET Biosensors

scientific article published in January 2016

Visualization of growth signal transduction cascades in living cells with genetically encoded probes based on Förster resonance energy transfer

scientific article published on June 2008

Visualization of small GTPase activity with fluorescence resonance energy transfer-based biosensors

scientific article published on 15 October 2009

[Dynamics of Rho-family G proteins as visualized with FRET-based probes]

scientific article published on 01 August 2005

[In vivo imaging of intracellular signaling molecules: Come/Stop signals of neutrophils during acute inflammation]

scientific article published on 01 June 2015

mTORC1 upregulation via ERK-dependent gene expression change confers intrinsic resistance to MEK inhibitors in oncogenic KRas-mutant cancer cells.

scientific article

Paulina is supported by:

About Paulina

Help