List of works - Lars E. French

Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape

scientific article published on 01 November 1996

Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin.

scientific article

Activation of the IL-1β-Processing Inflammasome Is Involved in Contact Hypersensitivity

article

The TRAIL to selective tumor death

scientific journal article

TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)

scientific article

Toxic epidermal necrolysis and Stevens-Johnson syndrome

scientific article

Inflammasome activation and IL-1β target IL-1α for secretion as opposed to surface expression

scientific article published on 17 October 2011

The Nlrp3 inflammasome regulates acute graft-versus-host disease

scientific article published on 26 August 2013

Caspase-4 is required for activation of inflammasomes

scientific article published on 13 January 2012

Treatment of toxic epidermal necrolysis with high-dose intravenous immunoglobulins: multicenter retrospective analysis of 48 consecutive cases

scientific article published on 01 January 2003

IL-1β drives inflammatory responses to propionibacterium acnes in vitro and in vivo.

scientific article published on 24 October 2013

BAFF production by antigen-presenting cells provides T cell co-stimulation.

scientific article published in March 2004

Interleukin-1, inflammasomes and the skin

scientific article published on September 2010

Tumor-infiltrating dendritic cells are potent antigen-presenting cells able to activate T cells and mediate tumor rejection.

scientific article published on January 2006

Visualization of lymphotoxin-beta and lymphotoxin-beta receptor expression in mouse embryos

scientific article published in May 2002

Diagnosis and management of nail pigmentations.

scientific article published on 22 February 2007

Cytotoxic Cutaneous Adverse Drug Reactions during Anti-PD-1 Therapy.

scientific article published on 8 March 2016

Myc-transformed epithelial cells down-regulate clusterin, which inhibits their growth in vitro and carcinogenesis in vivo.

scientific article

Diagnostic delay in hidradenitis suppurativa is a global problem

scientific article published on 3 November 2015

Squamous cell carcinoma of the skin shows a distinct microRNA profile modulated by UV radiation

scientific article published on 24 June 2010

Frequent loss of Fas expression and function in human lung tumours with overexpression of FasL in small cell lung carcinoma

scientific article

TNF-α and IFN-γ are potential inducers of Fas-mediated keratinocyte apoptosis through activation of inducible nitric oxide synthase in toxic epidermal necrolysis

scientific article

A randomized, double-blind, placebo-controlled trial of photopheresis in systemic sclerosis

scientific article published on 01 May 2006

Interleukin-1, inflammasomes, autoinflammation and the skin.

scientific article

RASopathic skin eruptions during vemurafenib therapy

scientific article

Interrupting IL-6–receptor signaling improves atopic dermatitis but associates with bacterial superinfection

article

High-throughput mutation profiling of CTCL samples reveals KRAS and NRAS mutations sensitizing tumors toward inhibition of the RAS/RAF/MEK signaling cascade.

scientific article published on 05 January 2011

Metastatic melanoma cell lines do not secrete IL-1β but promote IL-1β production from macrophages.

scientific article published on 24 January 2014

Chronological Order of Appearance of Extraintestinal Manifestations Relative to the Time of IBD Diagnosis in the Swiss Inflammatory Bowel Disease Cohort

scientific article

IL-31 expression by inflammatory cells is preferentially elevated in atopic dermatitis

scientific article published on 01 January 2012

Inhibition of death receptor signaling by FLICE-inhibitory protein as a mechanism for immune escape of tumors

scientific article published on October 1999

Possible neuroprotective role of clusterin in Alzheimer's disease: a quantitative immunocytochemical study

scientific article published on April 1, 1998

Resistance to FasL and tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in Sezary syndrome T-cells associated with impaired death receptor and FLICE-inhibitory protein expression

scientific article published on 26 February 2008

Canakinumab in adults with steroid-refractory pyoderma gangrenosum.

scientific article

Frequent downregulation of Fas (CD95) expression and function in melanoma

scientific article

Resiquimod, a topical drug for viral skin lesions and skin cancer.

scientific article published on 04 December 2012

Mitogen-activated protein/extracellular signal-regulated kinase kinase inhibition results in biphasic alteration of epidermal homeostasis with keratinocytic apoptosis and pigmentation disorders.

scientific article

Characterization of nivolumab-associated skin reactions in patients with metastatic non-small cell lung cancer

scientific article published on 19 September 2016

Intracellular localization of keratinocyte Fas ligand explains lack of cytolytic activity under physiological conditions.

scientific article published on 7 December 2002

Sézary syndrome patients demonstrate a defect in dendritic cell populations: effects of CD40 ligand and treatment with GM-CSF on dendritic cell numbers and the production of cytokines

scientific article published on 01 November 2002

Tumour hypoxia promotes melanoma growth and metastasis via High Mobility Group Box-1 and M2-like macrophages

scientific article

Sustained astrocytic clusterin expression improves remodeling after brain ischemia.

scientific article published on 10 February 2006

Malassezia yeasts activate the NLRP3 inflammasome in antigen-presenting cells via Syk-kinase signalling.

scientific article published on December 2014

Intravenous immunoglobulin: properties, mode of action and practical use in dermatology.

scientific article published on January 2007

Caspase-1 activity is required for UVB-induced apoptosis of human keratinocytes

scientific article published on 06 January 2015

Reversal of UVA skin photosensitivity and DNA damage in kidney transplant recipients by replacing azathioprine

scientific article published on 22 September 2011

Progression of cutaneous squamous cell carcinoma in immunosuppressed patients is associated with reduced CD123+ and FOXP3+ cells in the perineoplastic inflammatory infiltrate.

scientific article published in July 2009

Adverse cutaneous drug eruptions: current understanding.

scientific article

IFN-γ Primes Keratinocytes for HSV-1-Induced Inflammasome Activation

scientific article

Comparison of ixekizumab with ustekinumab in moderate-to-severe psoriasis: 24-week results from IXORA-S, a phase III study.

scientific article published on 19 May 2017

List of works by Lars E. French

Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape

Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin.

Activation of the IL-1β-Processing Inflammasome Is Involved in Contact Hypersensitivity

The TRAIL to selective tumor death

TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)

Toxic epidermal necrolysis and Stevens-Johnson syndrome

Inflammasome activation and IL-1β target IL-1α for secretion as opposed to surface expression

The Nlrp3 inflammasome regulates acute graft-versus-host disease

Caspase-4 is required for activation of inflammasomes

Treatment of toxic epidermal necrolysis with high-dose intravenous immunoglobulins: multicenter retrospective analysis of 48 consecutive cases

IL-1β drives inflammatory responses to propionibacterium acnes in vitro and in vivo.

BAFF production by antigen-presenting cells provides T cell co-stimulation.

Interleukin-1, inflammasomes and the skin

Tumor-infiltrating dendritic cells are potent antigen-presenting cells able to activate T cells and mediate tumor rejection.

Visualization of lymphotoxin-beta and lymphotoxin-beta receptor expression in mouse embryos

Diagnosis and management of nail pigmentations.

Cytotoxic Cutaneous Adverse Drug Reactions during Anti-PD-1 Therapy.

Myc-transformed epithelial cells down-regulate clusterin, which inhibits their growth in vitro and carcinogenesis in vivo.

Diagnostic delay in hidradenitis suppurativa is a global problem

Squamous cell carcinoma of the skin shows a distinct microRNA profile modulated by UV radiation

Frequent loss of Fas expression and function in human lung tumours with overexpression of FasL in small cell lung carcinoma

TNF-α and IFN-γ are potential inducers of Fas-mediated keratinocyte apoptosis through activation of inducible nitric oxide synthase in toxic epidermal necrolysis

A randomized, double-blind, placebo-controlled trial of photopheresis in systemic sclerosis

Interleukin-1, inflammasomes, autoinflammation and the skin.

RASopathic skin eruptions during vemurafenib therapy

Interrupting IL-6–receptor signaling improves atopic dermatitis but associates with bacterial superinfection

High-throughput mutation profiling of CTCL samples reveals KRAS and NRAS mutations sensitizing tumors toward inhibition of the RAS/RAF/MEK signaling cascade.

Metastatic melanoma cell lines do not secrete IL-1β but promote IL-1β production from macrophages.

Chronological Order of Appearance of Extraintestinal Manifestations Relative to the Time of IBD Diagnosis in the Swiss Inflammatory Bowel Disease Cohort

IL-31 expression by inflammatory cells is preferentially elevated in atopic dermatitis

Inhibition of death receptor signaling by FLICE-inhibitory protein as a mechanism for immune escape of tumors

Possible neuroprotective role of clusterin in Alzheimer's disease: a quantitative immunocytochemical study

Resistance to FasL and tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in Sezary syndrome T-cells associated with impaired death receptor and FLICE-inhibitory protein expression

Canakinumab in adults with steroid-refractory pyoderma gangrenosum.

Frequent downregulation of Fas (CD95) expression and function in melanoma

Resiquimod, a topical drug for viral skin lesions and skin cancer.

Mitogen-activated protein/extracellular signal-regulated kinase kinase inhibition results in biphasic alteration of epidermal homeostasis with keratinocytic apoptosis and pigmentation disorders.

Characterization of nivolumab-associated skin reactions in patients with metastatic non-small cell lung cancer

Intracellular localization of keratinocyte Fas ligand explains lack of cytolytic activity under physiological conditions.

Sézary syndrome patients demonstrate a defect in dendritic cell populations: effects of CD40 ligand and treatment with GM-CSF on dendritic cell numbers and the production of cytokines

Tumour hypoxia promotes melanoma growth and metastasis via High Mobility Group Box-1 and M2-like macrophages

Sustained astrocytic clusterin expression improves remodeling after brain ischemia.

Malassezia yeasts activate the NLRP3 inflammasome in antigen-presenting cells via Syk-kinase signalling.

Intravenous immunoglobulin: properties, mode of action and practical use in dermatology.

Caspase-1 activity is required for UVB-induced apoptosis of human keratinocytes

Reversal of UVA skin photosensitivity and DNA damage in kidney transplant recipients by replacing azathioprine

Progression of cutaneous squamous cell carcinoma in immunosuppressed patients is associated with reduced CD123+ and FOXP3+ cells in the perineoplastic inflammatory infiltrate.

Adverse cutaneous drug eruptions: current understanding.

IFN-γ Primes Keratinocytes for HSV-1-Induced Inflammasome Activation

Comparison of ixekizumab with ustekinumab in moderate-to-severe psoriasis: 24-week results from IXORA-S, a phase III study.