List of works by Aaron Beedle

AAV-mediated transfer of FKRP shows therapeutic efficacy in a murine model but requires control of gene expression.

scientific article published on 3 March 2017

Abnormal Skeletal Muscle Regeneration plus Mild Alterations in Mature Fiber Type Specification in Fktn-Deficient Dystroglycanopathy Muscular Dystrophy Mice

scientific article published on 11 January 2016

Adult stem cell deficits drive Slc29a3 disorders in mice

scientific article published on 03 July 2019

Aggregate mesenchymal stem cell delivery ameliorates the regenerative niche for muscle repair

scholarly article by Marissa A Ruehle et al published August 2018 in Journal of Tissue Engineering and Regenerative Medicine

Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

scientific article

Block of voltage-dependent calcium channels by aliphatic monoamines.

scientific article published on July 2000

Conformationally constrained peptides target the allosteric kinase dimer interface and inhibit EGFR activation.

scientific article published on 5 September 2017

Cryosectioning of Contiguous Regions of a Single Mouse Skeletal Muscle for Gene Expression and Histological Analyses.

scientific article published on 12 December 2016

Defective mucin-type glycosylation on α-dystroglycan in COG-deficient cells increases its susceptibility to bacterial proteases

article published in 2018

Design of a selenylsulfide-bridged EGFR dimerization arm mimic

scientific article published on 20 March 2015

Determinants of inhibition of transiently expressed voltage-gated calcium channels by omega-conotoxins GVIA and MVIIA.

scientific article published on 24 March 2003

Development of rabbit monoclonal antibodies for detection of alpha-dystroglycan in normal and dystrophic tissue

scientific article

Evidence for a role of dystroglycan regulating the membrane architecture of astroglial endfeet

scientific article published on 19 April 2011

Expression of T-type calcium channel splice variants in human glioma.

scientific article published on November 2004

Expression of voltage-gated Ca2+ channel subtypes in cultured astrocytes

scientific journal article

Four-week rapamycin treatment improves muscular dystrophy in a fukutin-deficient mouse model of dystroglycanopathy

scientific article published on 02 June 2016

Fukutin-related protein associates with the sarcolemmal dystrophin-glycoprotein complex

scientific journal article

G protein modulation of N-type calcium channels is facilitated by physical interactions between syntaxin 1A and Gbetagamma.

scientific article

Inhibiting EGFR dimerization using triazolyl-bridged dimerization arm mimics

scientific article

Inhibition of recombinant N-type Ca(V) channels by the gamma 2 subunit involves unfolded protein response (UPR)-dependent and UPR-independent mechanisms.

scientific article published on March 2007

Inhibition of subfornical organ neuronal potassium channels by vasopressin.

scientific article

LARGE2-dependent glycosylation confers laminin-binding ability on proteoglycans.

scientific article published on 22 July 2016

Lysophosphatidic Acid Mediates Activating Transcription Factor 3 Expression Which Is a Target for Post-Transcriptional Silencing by miR-30c-2-3p

scientific article published on 29 September 2015

Mitochondrial dysfunction in skeletal muscle of fukutin deficient mice is resistant to exercise- and AICAR-induced rescue

scientific article published on 24 August 2020

Mitochondrial maintenance via autophagy contributes to functional skeletal muscle regeneration and remodeling.

scientific article published on 8 June 2016

Mouse fukutin deletion impairs dystroglycan processing and recapitulates muscular dystrophy

scientific article

Mutation associated with an autosomal dominant cone-rod dystrophy CORD7 modifies RIM1-mediated modulation of voltage-dependent Ca2+ channels.

scientific article

ORL1 receptor-mediated internalization of N-type calcium channels

scientific article published on 27 November 2005

RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels.

scientific article published on 13 May 2007

Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels

scientific article

Regulator of G-Protein Signaling 5 Reduces HeyA8 Ovarian Cancer Cell Proliferation and Extends Survival in a Murine Tumor Model.

scientific article

Stabilization of the cardiac sarcolemma by sarcospan rescues DMD-associated cardiomyopathy

scientific article published on 30 April 2019

Suppression of the GTPase-activating protein RGS10 increases Rheb-GTP and mTOR signaling in ovarian cancer cells

scientific article

Synthesis and evaluation of a new class of nifedipine analogs with T-type calcium channel blocking activity.

scientific article published in March 2002

The CACNA1F gene encodes an L-type calcium channel with unique biophysical properties and tissue distribution

scientific article (publication date: 18 February 2004)

The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels

scientific article

Transient HIF2A inhibition promotes satellite cell proliferation and muscle regeneration.

scientific article published on 30 April 2018

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