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List of works by Hajime Karasuyama

Activation of basophils by the double-stranded RNA poly(A:U) exacerbates allergic inflammation.

scientific article published on 27 April 2013

Allergic skin sensitization promotes eosinophilic esophagitis through the IL-33-basophil axis in mice.

scientific article published on 19 April 2016

An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers.

scientific article

Antigen-Specific IgG ameliorates allergic airway inflammation via Fcγ receptor IIB on dendritic cells.

scientific article

BASH-novel PKC-Raf-1 pathway of pre-BCR signaling induces kappa gene rearrangement.

scientific article published on 22 June 2006

Basophil tryptase mMCP-11 plays a crucial role in IgE-mediated, delayed-onset allergic inflammation in mice

scientific article published on 27 October 2016

Basophil-derived IL-4 plays versatile roles in immunity.

scientific article published on 10 May 2016

Basophil-derived mouse mast cell protease 11 induces microvascular leakage and tissue edema in a mast cell-independent manner

scientific article published on 06 November 2011

Basophils Trigger Fibroblast Activation in Cardiac Allograft Fibrosis Development.

scientific article published on 28 March 2016

Basophils amplify type 2 immune responses, but do not serve a protective role, during chronic infection of mice with the filarial nematode Litomosoides sigmodontis

scientific article published on 05 November 2010

Basophils and mast cells in immunity and inflammation.

scientific article

Basophils and mast cells play critical roles for leukocyte recruitment in IgE-mediated cutaneous reverse passive Arthus reaction

scientific article published on 23 June 2012

Basophils are essential initiators of a novel type of chronic allergic inflammation

scientific article published on 04 April 2007

Basophils contribute to pristane-induced Lupus-like nephritis model

scientific article published on 11 August 2017

Basophils have emerged as a key player in immunity

scientific article published on 05 August 2014

Basophils help establish protective immunity induced by irradiated larval vaccination for filariasis

scientific article published on 15 June 2013

Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells

scientific article published on 01 August 2005

Basophils preferentially express mouse Mast Cell Protease 11 among the mast cell tryptase family in contrast to mast cells

scientific article published on 01 December 2009

CD41 is a reliable identification and activation marker for murine basophils in the steady state and during helminth and malarial infections

scientific article published on 10 April 2014

Chronic inflammation of the skin can be induced in IgE transgenic mice by means of a single challenge of multivalent antigen

scientific article published on 01 January 2003

Contribution of mast cell-derived interleukin-1β to uric acid crystal-induced acute arthritis in mice.

scientific article published on October 2014

Critical role of P1-Runx1 in mouse basophil development.

scientific article

Critical role of the neutrophil-associated high-affinity receptor for IgE in the pathogenesis of experimental cerebral malaria

scientific article

Defective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells.

scientific article

Deficiency of BLNK hampers PLC-gamma2 phosphorylation and Ca2+ influx induced by the pre-B-cell receptor in human pre-B cells.

scientific article published on August 2004

Differences in the Importance of Mast Cells, Basophils, IgE, and IgG versus That of CD4+ T Cells and ILC2 Cells in Primary and Secondary Immunity to Strongyloides venezuelensis

scientific article published on 6 March 2017

Dok-1 and Dok-2 are negative regulators of lipopolysaccharide-induced signaling

scientific article published on February 2005

Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome

scientific article published on 5 August 2007

Emerging roles of basophils in allergic inflammation.

scientific article

Emerging roles of basophils in protective immunity against parasites.

scientific article published on 16 December 2010

Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion.

scientific article

Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development

scientific article (publication date: March 2003)

Fc receptor gamma-chain, a constitutive component of the IL-3 receptor, is required for IL-3-induced IL-4 production in basophils

scientific article published on 21 December 2008

GATA-1 regulates the generation and function of basophils

scientific article published on 28 October 2013

Heterogeneity of Igh-linked allotypic determinants expressed on functional T cell subsets as detected by monoclonal antibodies ⬇️

scientific article published on May 1, 1984

Human eosinophils constitutively express a unique serine protease, PRSS33.

scientific article published on 16 February 2017

Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity

scientific article

IL-3 Triggers Chronic Rejection of Cardiac Allografts by Activation of Infiltrating Basophils

scientific article published on 08 May 2019

IgG-mediated systemic anaphylaxis to protein antigen can be induced even under conditions of limited amounts of antibody and antigen

scientific article published on 26 October 2010

Inflammatory monocytes recruited to allergic skin acquire an anti-inflammatory M2 phenotype via basophil-derived interleukin-4.

scientific article published on 21 February 2013

Intravital imaging of Ca(2+) signals in lymphocytes of Ca(2+) biosensor transgenic mice: indication of autoimmune diseases before the pathological onset.

scientific article

LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation

scientific article

Large particulate allergens can elicit mast cell-mediated anaphylaxis without exit from blood vessels as efficiently as do small soluble allergens.

scientific article published on 24 September 2015

MIP-1α/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice

scientific article

Melanocortin receptors 1 and 5 might mediate inhibitory effects of α-melanocyte-stimulating hormone on antigen-induced chronic allergic skin inflammation in IgE transgenic mice

scientific article published on 22 March 2012

Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome

scientific article published on June 2009

Mouse and human neutrophils induce anaphylaxis.

scientific article

NADPH oxidase-independent formation of extracellular DNA traps by basophils

scientific article

NK cell-depleting anti-asialo GM1 antibody exhibits a lethal off-target effect on basophils in vivo

scientific article published on 13 April 2011

Newly discovered roles for basophils: a neglected minority gains new respect.

scientific article published on January 2009

Nonredundant roles of basophils in immunity.

scientific article published on January 2011

Novel CD200 homologues iSEC1 and iSEC2 are gastrointestinal secretory cell-specific ligands of inhibitory receptor CD200R.

scientific article published on 7 November 2016

Ovalbumin-specific IgE modulates ovalbumin-specific T-cell response after repetitive oral antigen administration

scientific article published on 01 April 2005

Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis

scientific article published on 17 July 2016

Peanuts can contribute to anaphylactic shock by activating complement.

scientific article published on 3 January 2009

Pivotal role of STIM2, but not STIM1, in IL-4 production by IL-3-stimulated murine basophils

scientific article published on 09 April 2019

Placental extravillous cytotrophoblasts persistently express class I major histocompatibility complex molecules after human cytomegalovirus infection.

scientific article

Plasmacytic transcription factor Blimp-1 is repressed by Bach2 in B cells

scientific article published on 17 October 2006

Real-time imaging of mast cell degranulation in vitro and in vivo

scientific article published on 21 September 2016

Recent advances in understanding basophil-mediated Th2 immune responses

scientific article published on July 2017

Role of mast cells and basophils in IgE responses and in allergic airway hyperresponsiveness

scientific article

Selection of stereotyped VH81X-{micro}H chains via pre-B cell receptor early in ontogeny and their conservation in adults by marginal zone B cells

scientific article published on 20 May 2005

Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks

scientific article published on 26 July 2010

Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice.

scientific article published on August 2013

Skin CD4+ Memory T Cells Play an Essential Role in Acquired Anti-Tick Immunity through Interleukin-3-Mediated Basophil Recruitment to Tick-Feeding Sites

scientific article published on 16 October 2017

Skin thymic stromal lymphopoietin initiates Th2 responses through an orchestrated immune cascade

scientific article published in January 2013

Th2-inducing cytokines IL-4 and IL-33 synergistically elicit the expression of transmembrane TNF-α on macrophages through the autocrine action of IL-6

scientific article published on 03 March 2012

The ectoenzyme E-NPP3 negatively regulates ATP-dependent chronic allergic responses by basophils and mast cells.

scientific article published in February 2015

The skin is an important bulwark of acquired immunity against intestinal helminths.

scientific article published on 28 October 2013

The transfer of maternal antigen-specific IgG regulates the development of allergic airway inflammation early in life in an FcRn-dependent manner.

scientific article published on April 2010

Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis.

scientific article published on 21 July 2013

Trogocytosis of peptide-MHC class II complexes from dendritic cells confers antigen-presenting ability on basophils.

scientific article published on 17 January 2017

Visualization of Probiotic-Mediated Ca2+ Signaling in Intestinal Epithelial Cells In Vivo

scientific article

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