List of works - André G. Loxton

A Subgroup of Latently Mycobacterium tuberculosis Infected Individuals Is Characterized by Consistently Elevated IgA Responses to Several Mycobacterial Antigens.

scientific article

A broad profile of co-dominant epitopes shapes the peripheral Mycobacterium tuberculosis specific CD8+ T-cell immune response in South African patients with active tuberculosis

scientific article

Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa

scientific article

Antimycobacterial activity and molecular docking of methanolic extracts and compounds of marine fungi from Saldanha and False Bays, South Africa

scientific article published in 2022

B Cells Producing Type I Interferon Modulate Macrophage Polarization in Tuberculosis

scientific article published on 21 November 2017

B cells as multi-functional players during Mycobacterium tuberculosis infection and disease.

scientific article

Bifunctional T-cell-derived cytokines for the diagnosis of tuberculosis and treatment monitoring.

scientific article published on 22 August 2014

Combination of gene expression patterns in whole blood discriminate between tuberculosis infection states

scientific article

Complete genome sequencing of a non-syncytium-inducing HIV type 1 subtype D strain from Cape Town, South Africa

scientific article published in December 2007

Detection of a combination of serum IgG and IgA antibodies against selected mycobacterial targets provides promising diagnostic signatures for active TB.

scientific article

Development of a Gene Expression Assay for the Diagnosis of Mycobacterium bovis Infection in African Lions (Panthera leo).

scientific article published on 30 October 2015

Diagnostic Potential of Novel Salivary Host Biomarkers as Candidates for the Immunological Diagnosis of Tuberculosis Disease and Monitoring of Tuberculosis Treatment Response

scientific article

Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB.

scientific article published on 4 May 2016

Differential expression of host biomarkers in saliva and serum samples from individuals with suspected pulmonary tuberculosis.

scientific article

Emergence and diversity of different HIV-1 subtypes in South Africa, 2000-2001.

scientific article published in November 2009

Epigenetics and Proteomics Join Transcriptomics in the Quest for Tuberculosis Biomarkers

scientific article

Evaluation of cytokine responses against novel Mtb antigens as diagnostic markers for TB disease

scientific article published on 13 June 2016

Frequency of Mycobacterium tuberculosis-specific CD8+ T-cells in the course of anti-tuberculosis treatment

scientific article published on March 2015

Heparin-binding hemagglutinin induces IFN-γ(+) IL-2(+) IL-17(+) multifunctional CD4(+) T cells during latent but not active tuberculosis disease

scientific article

Host biomarkers detected in saliva show promise as markers for the diagnosis of pulmonary tuberculosis disease and monitoring of the response to tuberculosis treatment.

scientific article published on 12 February 2016

Host cytokine responses induced after overnight stimulation with novel M. tuberculosis infection phase-dependent antigens show promise as diagnostic candidates for TB disease

scientific article

Identification of novel host biomarkers in plasma as candidates for the immunodiagnosis of tuberculosis disease and monitoring of tuberculosis treatment response

scientific article published on 19 August 2016

Immunoglobulin profile and B-cell frequencies are altered with changes in the cellular microenvironment independent of the stimulation conditions

scientific article published on 08 July 2020

Increased frequency of myeloid-derived suppressor cells during active tuberculosis and after recent mycobacterium tuberculosis infection suppresses T-cell function

scientific article published on September 2013

Isolation of B-cells using Miltenyi MACS bead isolation kits

scientific article published on 20 March 2019

Medroxyprogesterone acetate alters Mycobacterium bovis BCG-induced cytokine production in peripheral blood mononuclear cells of contraceptive users

scientific article

Mycobacterium bovis BCG infection severely delays Trichuris muris expulsion and co-infection suppresses immune responsiveness to both pathogens.

scientific article

P16-01. Regulatory T-cells and high levels of FOXP3 mRNA leads to decreased immune responses in HIV-TB co-infection

scientific article published on 22 October 2009

Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure

scientific article

Phenotypic analysis of peripheral B cell populations during Mycobacterium tuberculosis infection and disease

scientific article published on 29 July 2016

Plasma Level of IL-4 Differs in Patients Infected with Different Modern Lineages of M. tuberculosis

scientific article

Potential of host markers produced by infection phase-dependent antigen-stimulated cells for the diagnosis of tuberculosis in a highly endemic area

scientific article

Potential of novel Mycobacterium tuberculosis infection phase-dependent antigens in the diagnosis of TB disease in a high burden setting

scientific article

Prevalence and Risk Factors for Mycobacterium bovis Infection in African Lions ( Panthera leo ) in the Kruger National Park.

scientific article published on 25 January 2017

QuantiFERON-TB performance enhanced by novel Mycobacterium tuberculosis-specific antigens

scientific article

Regulatory B lymphocytes: development and modulation of the host immune response during disease

scientific article published on 10 April 2019

Safety and Immunogenicity of the Recombinant Mycobacterium bovis BCG Vaccine VPM1002 in HIV-Unexposed Newborn Infants in South Africa

scientific article published on 14 December 2016

Sequence analysis of near full-length HIV type 1 subtype D primary strains isolated in Cape Town, South Africa, from 1984 to 1986.

scientific article published in May 2005

Serologic diagnosis of tuberculosis by combining Ig classes against selected mycobacterial targets.

scientific article

Sputum is a surrogate for bronchoalveolar lavage for monitoring Mycobacterium tuberculosis transcriptional profiles in TB patients

scientific article published on 25 July 2016

Successful TB treatment induces B-cells expressing FASL and IL5RA mRNA.

scientific article published on 22 September 2016

The Functional Response of B Cells to Antigenic Stimulation: A Preliminary Report of Latent Tuberculosis

scientific article

Transcriptomics: the key to biomarker discovery during tuberculosis?

scientific article published on January 2015

List of works by André G. Loxton

A Subgroup of Latently Mycobacterium tuberculosis Infected Individuals Is Characterized by Consistently Elevated IgA Responses to Several Mycobacterial Antigens.

A broad profile of co-dominant epitopes shapes the peripheral Mycobacterium tuberculosis specific CD8+ T-cell immune response in South African patients with active tuberculosis

Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa

Antimycobacterial activity and molecular docking of methanolic extracts and compounds of marine fungi from Saldanha and False Bays, South Africa

B Cells Producing Type I Interferon Modulate Macrophage Polarization in Tuberculosis

B cells as multi-functional players during Mycobacterium tuberculosis infection and disease.

Bifunctional T-cell-derived cytokines for the diagnosis of tuberculosis and treatment monitoring.

Combination of gene expression patterns in whole blood discriminate between tuberculosis infection states

Complete genome sequencing of a non-syncytium-inducing HIV type 1 subtype D strain from Cape Town, South Africa

Detection of a combination of serum IgG and IgA antibodies against selected mycobacterial targets provides promising diagnostic signatures for active TB.

Development of a Gene Expression Assay for the Diagnosis of Mycobacterium bovis Infection in African Lions (Panthera leo).

Diagnostic Potential of Novel Salivary Host Biomarkers as Candidates for the Immunological Diagnosis of Tuberculosis Disease and Monitoring of Tuberculosis Treatment Response

Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB.

Differential expression of host biomarkers in saliva and serum samples from individuals with suspected pulmonary tuberculosis.

Emergence and diversity of different HIV-1 subtypes in South Africa, 2000-2001.

Epigenetics and Proteomics Join Transcriptomics in the Quest for Tuberculosis Biomarkers

Evaluation of cytokine responses against novel Mtb antigens as diagnostic markers for TB disease

Frequency of Mycobacterium tuberculosis-specific CD8+ T-cells in the course of anti-tuberculosis treatment

Heparin-binding hemagglutinin induces IFN-γ(+) IL-2(+) IL-17(+) multifunctional CD4(+) T cells during latent but not active tuberculosis disease

Host biomarkers detected in saliva show promise as markers for the diagnosis of pulmonary tuberculosis disease and monitoring of the response to tuberculosis treatment.

Host cytokine responses induced after overnight stimulation with novel M. tuberculosis infection phase-dependent antigens show promise as diagnostic candidates for TB disease

Identification of novel host biomarkers in plasma as candidates for the immunodiagnosis of tuberculosis disease and monitoring of tuberculosis treatment response

Immunoglobulin profile and B-cell frequencies are altered with changes in the cellular microenvironment independent of the stimulation conditions

Increased frequency of myeloid-derived suppressor cells during active tuberculosis and after recent mycobacterium tuberculosis infection suppresses T-cell function

Isolation of B-cells using Miltenyi MACS bead isolation kits

Medroxyprogesterone acetate alters Mycobacterium bovis BCG-induced cytokine production in peripheral blood mononuclear cells of contraceptive users

Mycobacterium bovis BCG infection severely delays Trichuris muris expulsion and co-infection suppresses immune responsiveness to both pathogens.

P16-01. Regulatory T-cells and high levels of FOXP3 mRNA leads to decreased immune responses in HIV-TB co-infection

Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure

Phenotypic analysis of peripheral B cell populations during Mycobacterium tuberculosis infection and disease

Plasma Level of IL-4 Differs in Patients Infected with Different Modern Lineages of M. tuberculosis

Potential of host markers produced by infection phase-dependent antigen-stimulated cells for the diagnosis of tuberculosis in a highly endemic area

Potential of novel Mycobacterium tuberculosis infection phase-dependent antigens in the diagnosis of TB disease in a high burden setting

Prevalence and Risk Factors for Mycobacterium bovis Infection in African Lions ( Panthera leo ) in the Kruger National Park.

QuantiFERON-TB performance enhanced by novel Mycobacterium tuberculosis-specific antigens

Regulatory B lymphocytes: development and modulation of the host immune response during disease

Safety and Immunogenicity of the Recombinant Mycobacterium bovis BCG Vaccine VPM1002 in HIV-Unexposed Newborn Infants in South Africa

Sequence analysis of near full-length HIV type 1 subtype D primary strains isolated in Cape Town, South Africa, from 1984 to 1986.

Serologic diagnosis of tuberculosis by combining Ig classes against selected mycobacterial targets.

Sputum is a surrogate for bronchoalveolar lavage for monitoring Mycobacterium tuberculosis transcriptional profiles in TB patients

Successful TB treatment induces B-cells expressing FASL and IL5RA mRNA.

The Functional Response of B Cells to Antigenic Stimulation: A Preliminary Report of Latent Tuberculosis

Transcriptomics: the key to biomarker discovery during tuberculosis?