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List of works by Elaine Fuchs

A Presenilin-2-ARF4 trafficking axis modulates Notch signaling during epidermal differentiation

scientific article

A breath of fresh air in lung regeneration

scientific article published on October 2011

A decade of molecular cell biology: achievements and challenges

scientific article published on 23 September 2011

A developmental conundrum: a stabilized form of beta-catenin lacking the transcriptional activation domain triggers features of hair cell fate in epidermal cells and epidermal cell fate in hair follicle cells

scientific article

A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis ⬇️

scientific article published on May 15, 2012

A family business: stem cell progeny join the niche to regulate homeostasis ⬇️

scientific article published on January 23, 2012

A matter of life and death: self‐renewal in stem cells ⬇️

scientific article published on December 11, 2012

A miR image of stem cells and their lineages

scientific article published on January 2012

A role for alphabeta1 integrins in focal adhesion function and polarized cytoskeletal dynamics

scientific article published in September 2003

A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

scientific journal article

A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis

scientific article

A skin microRNA promotes differentiation by repressing 'stemness'.

scientific article

A two-step mechanism for stem cell activation during hair regeneration

scientific article

ACF7 is a hair-bundle antecedent, positioned to integrate cuticular plate actin and somatic tubulin

scientific article

ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity

scientific article

ACF7: an essential integrator of microtubule dynamics

scientific article (publication date: 31 October 2003)

AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis

scientific journal article

AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis

scientific article

Alpha-catenin: at the junction of intercellular adhesion and actin dynamics

scientific article published in August 2004

An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration

scientific article published on 4 April 2012

An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis

scientific article published on 25 September 2019

An unconventional route to becoming a cell biologist.

scientific article

Architectural niche organization by LHX2 is linked to hair follicle stem cell function

scientific journal article

Asymmetric cell divisions promote Notch-dependent epidermal differentiation

scientific article

Asymmetric cell divisions promote stratification and differentiation of mammalian skin

scientific article

Author Correction: Extracellular serine controls epidermal stem cell fate and tumour initiation

scientific article published on 12 October 2020

Author Correction: Inflammatory memory sensitizes skin epithelial stem cells to tissue damage

scientific article published in Nature

BMP signaling and its pSMAD1/5 target genes differentially regulate hair follicle stem cell lineages

scientific article published on 9 October 2014

BMP signaling in dermal papilla cells is required for their hair follicle-inductive properties

scientific article

BPAG1n4 is essential for retrograde axonal transport in sensory neurons

scientific article

Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium

scientific article

Beta 1-integrins are required for hippocampal AMPA receptor-dependent synaptic transmission, synaptic plasticity, and working memory

scientific article published on January 2006

Biogenesis and function of mouse mammary epithelium depends on the presence of functional alpha-catenin

scientific article published on January 2004

Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland

scientific journal article

Building confidence: the transition from student to professor

scientific article published on July 2009

CLASP2 interacts with p120-catenin and governs microtubule dynamics at adherens junctions

scientific article

Canonical notch signaling functions as a commitment switch in the epidermal lineage

scientific journal article

Catenins: keeping cells from getting their signals crossed

scientific article published on November 2006

Cell biology: More than skin deep

scientific article published on June 2015

Chronic centrosome amplification without tumorigenesis

scientific article

Comparison of REST cistromes across human cell types reveals common and context-specific functions

scientific article

Complementary DNA sequence of a human cytoplasmic actin

scholarly article

Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses

scholarly article

Coordinating cytoskeletal tracks to polarize cellular movements

scientific article published in October 2004

Corrigendum: Mitotic internalization of planar cell polarity proteins preserves tissue polarity

scientific article published in January 2017

Coupling organelle inheritance with mitosis to balance growth and differentiation

scientific article

Cyfip1 is a putative invasion suppressor in epithelial cancers

scientific article

Cédric Blanpain: ISSCR's Outstanding Young Investigator for 2012 ⬇️

scientific article published on June 14, 2012

DGCR8-dependent microRNA biogenesis is essential for skin development

scholarly article

DNA methylation dynamics during in vivo differentiation of blood and skin stem cells

scientific article published on 26 July 2012

Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA.

scientific article

Defining the epithelial stem cell niche in skin

scientific article (publication date: 16 January 2004)

Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells

scientific article

Desmoplakin: an unexpected regulator of microtubule organization in the epidermis

scientific article

Developmental roles for Srf, cortical cytoskeleton and cell shape in epidermal spindle orientation

scientific article

Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a

scientific journal article

Direct in vivo RNAi screen unveils myosin IIa as a tumor suppressor of squamous cell carcinomas

scientific article published on January 2014

Dissection of a complex enhancer element: maintenance of keratinocyte specificity but loss of differentiation specificity

scientific article

Dynamics between Stem Cells, Niche, and Progeny in the Hair Follicle ⬇️

scientific article published on January 7, 2011

ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomas

scientific article published on 21 November 2015

EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair

scientific article

Elaine Fuchs. Interview by Hannah Stower

scientific article

Elaine Fuchs: A love for science that's more than skin deep. Interviewed by Ben Short

scientific article published on December 2009

Emerging interactions between skin stem cells and their niches

scientific article

Epidermal development, growth control, and homeostasis in the face of centrosome amplification

scientific article

Epidermal homeostasis: a balancing act of stem cells in the skin

scientific article

Epidermal stem cells of the skin

scientific article published on January 2006

Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility

scientific article published on July 2009

Epithelial Skin Biology: Three Decades of Developmental Biology, a Hundred Questions Answered and a Thousand New Ones to Address

scientific article published on 8 February 2016

Epithelial stem cells: turning over new leaves

scientific article published on February 2007

Epithelial-Mesenchymal Micro-niches Govern Stem Cell Lineage Choices

scientific article published on 10 April 2017

Expression of conditional cre recombinase in epithelial tissues of transgenic mice

scientific article published on February 2003

Extracellular serine controls epidermal stem cell fate and tumour initiation

scientific article published on 25 May 2020

Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells

scientific journal article

FOXC1 maintains the hair follicle stem cell niche and governs stem cell quiescence to preserve long-term tissue-regenerating potential

scientific article published on 24 February 2016

Ferreting out stem cells from their niches ⬇️

scientific article published on May 1, 2011

Fibroblast growth factor-10 is a mitogen for urothelial cells

scientific article

Finding one's niche in the skin

scientific article published on June 2009

Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics

scientific article

Forces generated by cell intercalation tow epidermal sheets in mammalian tissue morphogenesis

scientific article

Function of Wnt/β-catenin in counteracting Tcf3 repression through the Tcf3-β-catenin interaction

scientific article

GATA-3: an unexpected regulator of cell lineage determination in skin

scientific journal article

Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage

scientific article

Getting under the skin of epidermal morphogenesis

scientific article

Governing epidermal homeostasis by coupling cell-cell adhesion to integrin and growth factor signaling, proliferation, and apoptosis ⬇️

scientific journal article

Guilt by association: what p120-catenin has to hide

scientific article

HESX1- and TCF3-mediated repression of Wnt/β-catenin targets is required for normal development of the anterior forebrain

scientific article

Hair follicle stem cells are specified and function in early skin morphogenesis

scientific article

Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor

scientific article

High Throughput strategies Aimed at Closing the GAP in Our Knowledge of Rho GTPase Signaling

scientific article published on 09 June 2020

Identification of stem cell populations in sweat glands and ducts reveals roles in homeostasis and wound repair

scientific article

Impaired Epidermal to Dendritic T Cell Signaling Slows Wound Repair in Aged Skin

scientific article

In vivo differentiation potential of tracheal basal cells: evidence for multipotent and unipotent subpopulations

scientific article published on 18 July 2003

Inflammatory memory and tissue adaptation in sickness and in health

scientific article published in 2022

Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor

scientific article published in Nature

Intercellular adhesion, signalling and the cytoskeleton

scientific article (publication date: April 2002)

Interferon-γ links ultraviolet radiation to melanomagenesis in mice

scientific article

In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators

scientific article published on 26 January 2014

Isolation and culture of epithelial stem cells

scientific article published on January 2009

LIM Homeobox Domain 2 Is Required for Corneal Epithelial Homeostasis

scientific article published on 13 December 2015

Lhx2 maintains stem cell character in hair follicles

scientific article published on June 2006

Links between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skin

scientific article

Links between signal transduction, transcription and adhesion in epithelial bud development

scientific article published on March 2003

Liquid-liquid phase separation drives skin barrier formation

scientific article published on 01 March 2020

Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia

scientific article

Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling

scholarly article

Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome

scientific article

Loss of p120 catenin and links to mitotic alterations, inflammation, and skin cancer

scholarly article

Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables

scientific journal article

Mechanics of a multilayer epithelium instruct tumour architecture and function

scientific article published on 02 September 2020

Mice cloned from skin cells

scholarly article

Mice in the world of stem cell biology

scientific article

MicroRNAs and their roles in mammalian stem cells

scientific article published on June 2011

Mitotic internalization of planar cell polarity proteins preserves tissue polarity ⬇️

scientific article published on July 10, 2011

Molecular cloning and characterization of AP-2 epsilon, a fifth member of the AP-2 family

scientific article

Molecular dissection of mesenchymal-epithelial interactions in the hair follicle

scientific article

More than one way to skin . .

scientific article

More than skin deep

scientific article published in Nature

Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs

scientific journal article

NFATc1 balances quiescence and proliferation of skin stem cells

scientific journal article

NFI transcription factors provide chromatin access to maintain stem cell identity while preventing unintended lineage fate choices

scientific article published on 11 May 2020

NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche

scientific article published on 6 February 2013

New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity

scholarly article

Nfatc1 orchestrates aging in hair follicle stem cells

scientific article

Oriented divisions, fate decisions

scientific article

Par3-mInsc and Gαi3 cooperate to promote oriented epidermal cell divisions through LGN.

scientific article

Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation ⬇️

scientific article published on January 6, 2012

Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice

scientific article

Planar cell polarity protein Celsr1 regulates endothelial adherens junctions and directed cell rearrangements during valve morphogenesis

scientific article published on 20 June 2013

Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles

scientific journal article

Progenitors oppositely polarize WNT activators and inhibitors to orchestrate tissue development

scientific article published on 20 April 2020

Protection of the intestinal mucosa by intraepithelial gamma delta T cells

scientific article

Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine

scientific journal article

Publisher Correction: Mechanics of a multilayer epithelium instruct tumour architecture and function

scientific article published on 11 September 2020

RNAi screens in mice identify physiological regulators of oncogenic growth

scientific article published on 14 August 2013

RNAi-mediated gene function analysis in skin

scientific article

Rapid and widespread suppression of self-renewal by microRNA-203 during epidermal differentiation

scientific article published on May 2013

Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos

scientific article

Reflections of an ISSCR President, 2010–2011 ⬇️

scientific article published on June 3, 2011

Regenerative medicine: An eye to treating blindness

scientific article published on July 2010

Reprogramming somatic cells to their embryonic state

scientific article published on 27 July 2007

SOX9: a stem cell transcriptional regulator of secreted niche signaling factors

scientific article published on February 2014

Scratching the surface of skin development

scientific article

Sept4/ ARTS Regulates Stem Cell Apoptosis and Skin Regeneration ⬇️

scientific article published on June 20, 2013

Sgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle

scientific article

Signaling function of alpha-catenin in microtubule regulation

scientific article

Skin Stem Cells Orchestrate Directional Migration by Regulating Microtubule-ACF7 Connections through GSK3β ⬇️

scientific article published on February 4, 2011

Skin Stem Cells in Silence, Action, and Cancer.

scientific article

Skin and Its Regenerative Powers: An Alliance between Stem Cells and Their Niche

scientific article published in November 2017

Skin stem cells: rising to the surface

scientific article

Socializing with the neighbors: stem cells and their niche

scientific article

Spatiotemporal antagonism in mesenchymal-epithelial signaling in sweat versus hair fate decision

scientific article

Specific MicroRNAs Are Preferentially Expressed by Skin Stem Cells To Balance Self-Renewal and Early Lineage Commitment ⬇️

scientific article published on March 4, 2011

Spectraplakins: master orchestrators of cytoskeletal dynamics

scientific article

Spindle orientation and epidermal morphogenesis

scientific article published on 23 September 2013

Stem cell plasticity. Plasticity of epithelial stem cells in tissue regeneration

scientific article

Stem cell-driven lymphatic remodeling coordinates tissue regeneration

scientific article

Stem cells in the skin: waste not, Wnt not.

scientific article

Stem cells of the skin epithelium

scientific article

Stem cells repurpose proliferation to contain a breach in their niche barrier

Stem cells: Aging and transcriptional fingerprints

scientific article

Sticky business: orchestrating cellular signals at adherens junctions

scientific article

Strand-specific in vivo screen of cancer-associated miRNAs unveils a role for miR-21(∗) in SCC progression

scientific article published on 30 November 2015

Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer

scientific article published on 26 February 2018

Structure and transcription of the human m3 muscarinic receptor gene

scientific article published in March 2002

Structure of the ACF7 EF-Hand-GAR Module and Delineation of Microtubule Binding Determinants.

scientific article published on 8 June 2017

Susan Lee Lindquist (1949-2016).

scientific article published in December 2016

Sweat gland progenitors in development, homeostasis, and wound repair

scientific article published on February 2014

TGF-β promotes heterogeneity and drug resistance in squamous cell carcinoma

scientific article published in February 2015

Targeted disruption of the murine zyxin gene

scientific article

Targeted p120-catenin ablation disrupts dental enamel development

scientific article

Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia

scientific journal article

Tcf3 governs stem cell features and represses cell fate determination in skin

scientific article published on October 2006

Tcf3: a transcriptional regulator of axis induction in the early embryo

scientific article (publication date: 2004)

The Harmonies Played by TGF-β in Stem Cell Biology ⬇️

scientific article published on December 7, 2012

The Impact of Cell Culture on Stem Cell Research ⬇️

scientific article published on June 14, 2012

The LEF1/beta -catenin complex activates movo1, a mouse homolog of Drosophila ovo required for epidermal appendage differentiation

scientific article

The Yin and Yang of Chromatin Dynamics In Stem Cell Fate Selection

scientific article published on 12 December 2015

The cellular basis of mechanosensory Merkel-cell innervation during development

scientific article published on 22 February 2019

The hair cycle

scientific article

The tortoise and the hair: slow-cycling cells in the stem cell race

scientific article published on May 2009

Tissue patterning and cellular mechanics

scientific article

Toward a knowledge of causes

scientific article

Transit-amplifying cells orchestrate stem cell activity and tissue regeneration

scientific article published on May 2014

Translation from unconventional 5' start sites drives tumour initiation

scientific article

Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-β and integrin/focal adhesion kinase (FAK) signaling

scientific article

UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling

scientific article published on 08 August 2013

Vitamin A resolves lineage plasticity to orchestrate stem cell lineage choices

scientific article published on 07 March 2024

WNT-SHH Antagonism Specifies and Expands Stem Cells prior to Niche Formation

scientific article

Wdr1-mediated cell shape dynamics and cortical tension are essential for epidermal planar cell polarity

scientific article

What does the concept of the stem cell niche really mean today?

scientific article

Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling

scientific article

Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin ⬇️

scientific article published on January 24, 2011

erratum: Links between signal transduction, transcription and adhesion in epithelial bud development

article

miR-125b can enhance skin tumor initiation and promote malignant progression by repressing differentiation and prolonging cell survival

scientific article

p120-catenin mediates inflammatory responses in the skin

scientific article

p63: revving up epithelial stem-cell potential

scientific article published on 01 July 2007

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