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List of works by Eduardo Munoz

3-Phenylcoumarins as inhibitors of HIV-1 replication.

scientific article

4-Phenylcoumarins as HIV transcription inhibitors.

scientific article

A Meroterpenoid NF-κB Inhibitor and Drimane Sesquiterpenoids from Asafetida

scientific article published on 01 July 2006

A cannabigerol derivative suppresses immune responses and protects mice from experimental autoimmune encephalomyelitis

scientific article (publication date: 2014)

A cannabigerol quinone alleviates neuroinflammation in a chronic model of multiple sclerosis.

scientific article

A cardiac glucoside with in vitro anti-HIV activity isolated from Elaeodendron croceum

scientific article published on November 2010

A prenylbisabolane with NF-kappaB inhibiting properties from Cascarilla (Croton eluteria).

scientific article published in July 2005

AM404 inhibits NFAT and NF-κB signaling pathways and impairs migration and invasiveness of neuroblastoma cells

scientific article

AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity

scientific article published on 13 December 2017

Alleviation of Microglial Activation Induced by p38 MAPK/MK2/PGE2 Axis by Capsaicin: Potential Involvement of other than TRPV1 Mechanism/s.

scientific article published on 8 March 2017

An aqueous stem bark extract of Mangifera indica (Vimang) inhibits T cell proliferation and TNF-induced activation of nuclear transcription factor NF-kappaB

scientific article published on 01 March 2005

Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway.

scientific article published on February 2003

Anti-HIV activity of some synthetic lignanolides and intermediates.

scientific article published in September 2004

Anti-HIV activity of stilbene-related heterocyclic compounds

scientific article published on 18 May 2006

Anti-Tat and anti-HIV activities of trimers of n-alkylglycines.

scientific article published on 6 January 2006

Anti-inflammatory activity of flavonoids from Eupatorium arnottianum

scientific article

Anti-inflammatory sesquiterpene lactones from Onopordum illyricum L. (Asteraceae), an Italian medicinal plant

scientific article published on 18 November 2016

Antiretroviral drugs do not interfere with bryostatin-mediated HIV-1 latency reversal.

scientific article published on 28 September 2015

Antitumor effects of two novel naturally occurring terpene quinones isolated from the Mediterranean ascidian Aplidium conicum.

scientific article

Arzanol, an anti-inflammatory and anti-HIV-1 phloroglucinol alpha-Pyrone from Helichrysum italicum ssp. microphyllum

scientific article

Ascorbic acid enhances the inhibitory effect of aspirin on neuronal cyclooxygenase-2-mediated prostaglandin E2 production

scientific article (publication date: May 2006)

Azorellane diterpenoids from Laretia acaulis inhibit nuclear factor-kappa B activity

scientific article published on 01 November 2007

Benefits of VCE-003.2, a cannabigerol quinone derivative, against inflammation-driven neuronal deterioration in experimental Parkinson's disease: possible involvement of different binding sites at the PPARγ receptor

scientific article published on 16 January 2018

Bioactive Prenylogous Cannabinoid from Fiber Hemp (Cannabis sativa)

scientific article published on 08 September 2011

Bioactive alkenylphenols from Piper obliquum.

scientific article published on 16 January 2008

Bioguided extraction of polyphenols from grape marc by using an alternative supercritical-fluid extraction method based on a liquid solvent trap

scientific article published on 20 February 2004

Biological characterization of PM226, a chromenoisoxazole, as a selective CB2 receptor agonist with neuroprotective profile.

scientific article published on 21 March 2016

Bryostatin activates HIV-1 latent expression in human astrocytes through a PKC and NF-ĸB-dependent mechanism

scientific article published on 22 July 2015

Bryostatin-1 for latent virus reactivation in HIV-infected patients on antiretroviral therapy

scientific article

Bryostatin-1 synergizes with histone deacetylase inhibitors to reactivate HIV-1 from latency.

scientific article published on September 2010

CHK2 stability is regulated by the E3 ubiquitin ligase SIAH2.

scientific article published on 11 January 2016

Caffeic acid phenethyl ester inhibits T-cell activation by targeting both nuclear factor of activated T-cells and NF-kappaB transcription factors.

scientific article published on 14 November 2003

Cannabinoid derivatives acting as dual PPARγ/CB2 agonists as therapeutic agents for systemic sclerosis

scientific article published on 27 February 2019

Cannabinoids in Metabolic Syndrome and Cardiac Fibrosis

scientific article published on 21 October 2020

Cannabinoquinones: Synthesis and Biological Profile

scientific article published in 2021

Cell death induced by Bothrops asper snake venom metalloproteinase on endothelial and other cell lines.

scientific article published on 26 February 2010

Cellular redox state and activating protein-1 are involved in ascorbate effect on calcitriol-induced differentiation.

scientific article published in January 2001

Clavaminols A-F, novel cytotoxic 2-amino-3-alkanols from the ascidian Clavelina phlegraea.

scientific article

Clinoptilolite in Dextran Sulphate Sodium-Induced Murine Colitis: Efficacy and Safety of a Microparticulate Preparation.

scientific article published in December 2017

Combination of biological screening in a cellular model of viral latency and virtual screening identifies novel compounds that reactivate HIV-1

scientific article

Corrigendum to "Biological characterization of PM226, a chromenoisoxazole, as a selective CB2 receptor agonist with neuroprotective profile" [Pharmacol. Res. 110 (August 2016) (2016) 205-215].

scientific article published on 19 April 2017

Coumarins from Opopanax chironium. New dihydrofuranocoumarins and differential induction of apoptosis by imperatorin and heraclenin.

scientific article published in April 2004

Denbinobin inhibits nuclear factor-kappaB and induces apoptosis via reactive oxygen species generation in human leukemic cells.

scientific article published on 21 January 2009

Detrimental effects of tropisetron on permanent ischemic stroke in the rat.

scientific article

Differential effects of phorbol-13-monoesters on human immunodeficiency virus reactivation.

scientific article published on 23 December 2007

EHP-101, an oral formulation of the cannabidiol aminoquinone VCE-004.8, alleviates bleomycin-induced skin and lung fibrosis

scientific article published on 02 August 2018

Effect of natural and semi-synthetic cadinanes from Heterotheca inuloides on NF-κB, Nrf2 and STAT3 signaling pathways and evaluation of their in vitro cytotoxicity in human cancer cell lines.

scientific article

Electrophilic Triterpenoid Enones: A Comparative Thiol-Trapping and Bioactivity Study.

scientific article published on 28 July 2017

Extracellular HIV type 1 Tat protein induces CD69 expression through NF-kappaB activation: possible correlation with cell surface Tat-binding proteins.

scientific article

From top to bottom: the two faces of HIPK2 for regulation of the hypoxic response.

scientific article published in June 2009

Galiellalactone is a direct inhibitor of the transcription factor STAT3 in prostate cancer cells

scientific article

Human immunodeficiency virus 1 Tat binds to dipeptidyl aminopeptidase IV (CD26): a possible mechanism for Tat's immunosuppressive activity.

scientific article published on July 1994

Human immunodeficiency virus type 1 Tat increases the expression of cleavage and polyadenylation specificity factor 73-kilodalton subunit modulating cellular and viral expression

scientific article

Hypoxia mimetic activity of VCE-004.8, a cannabidiol quinone derivative: implications for multiple sclerosis therapy

scientific article published in March 2018

Hypoximimetic activity of N-acyl-dopamines. N-arachidonoyl-dopamine stabilizes HIF-1α protein through a SIAH2-dependent pathway

scientific article published on 02 August 2014

Imperatorin inhibits T-cell proliferation by targeting the transcription factor NFAT.

scientific article published in November 2004

In vitro anti-HIV-1 properties of ethnobotanically selected South African plants used in the treatment of sexually transmitted diseases.

scientific article published on 2 September 2008

Incensole acetate: a novel neuroprotective agent isolated from Boswellia carterii.

scientific article

Induction of apoptosis in human mitogen-activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3: involvement of the Fas receptor/ligand system.

scientific article

Inhibition of NF-κB activation and expression of inflammatory mediators by polyacetylene spiroketals from Plagius flosculosus

scientific article published on 01 June 2005

Inhibition of dipeptidyl aminopeptidase IV (DP-IV) by Xaa-boroPro dipeptides and use of these inhibitors to examine the role of DP-IV in T-cell function ⬇️

scientific article published on February 15, 1991

Intensification of antiretroviral therapy with a CCR5 antagonist in patients with chronic HIV-1 infection: effect on T cells latently infected

scientific article (publication date: 2011)

Interleukin-1 induces c-fos and c-jun gene expression in T helper type II cells through different signal transmission pathways

scientific article published on August 1, 1992

Interleukin-1 induces protein tyrosine phosphorylation in T cells

scientific article published on June 1, 1992

Involvement of mitochondria and caspase-3 in ET-18-OCH(3)-induced apoptosis of human leukemic cells

scientific article published in April 2000

Involvement of reactive oxygen species in capsaicinoid-induced apoptosis in transformed cells

scientific article published in June 2003

Iodinated N-acylvanillamines: potential "multiple-target" anti-inflammatory agents acting via the inhibition of t-cell activation and antagonism at vanilloid TRPV1 channels.

scientific article published on 4 January 2006

Levels of HBV-DNA and HBsAg after acute liver allograft rejection treatment by corticoids and OKT3

scientific article published on 01 June 2000

Mesuol, a natural occurring 4-phenylcoumarin, inhibits HIV-1 replication by targeting the NF-kappaB pathway.

scientific article published on 20 April 2005

Metabolomic profiling of human lung tumor tissues - nucleotide metabolism as a candidate for therapeutic interventions and biomarkers

scientific article published on 13 September 2018

Molecular targets of the antiinflammatory Harpagophytum procumbens (devil's claw): inhibition of TNFα and COX-2 gene expression by preventing activation of AP-1.

scientific article

Mutual regulation between SIAH2 and DYRK2 controls hypoxic and genotoxic signaling pathways.

scientific article

Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-κB Pathways

scientific article published on 19 February 2017

Neuroactive and Anti-inflammatory Frankincense Cembranes: A Structure-Activity Study.

scientific article published on 28 June 2016

Neuroprotective effects of the cannabigerol quinone derivative VCE-003.2 in SOD1G93A transgenic mice, an experimental model of amyotrophic lateral sclerosis

scientific article published on 01 August 2018

Neuroprotective properties of cannabigerol in Huntington's disease: studies in R6/2 mice and 3-nitropropionate-lesioned mice.

scientific article

Nuclear factor-kappa B activity in T cells from patients with rheumatic diseases: a preliminary report.

scientific article published on December 1998

Opposite effects of anandamide and N-arachidonoyl dopamine in the regulation of prostaglandin E and 8-iso-PGF formation in primary glial cells

scientific article

Phenylpropanoid NF-kappaB inhibitors from Bupleurum fruticosum

scientific article published on 01 October 2004

Physalins from Witheringia solanacea as modulators of the NF-kappaB cascade.

scientific article published on March 2006

Phytocannabinoids: a unified critical inventory

scientific article

Poly-Electrophilic Sesquiterpene Lactones from Vernonia amygdalina: New Members and Differences in Their Mechanism of Thiol Trapping and in Bioactivity

scientific article

Polyomavirus enhancer-binding protein 2/core binding factor/acute myeloid leukemia factors contribute to the cell type-specific activity of the CD11a integrin gene promoter.

scientific article published on September 2000

Production of functional active human growth factors in insects used as living biofactories.

scientific article published on 7 June 2014

Pseudoephedrine inhibits T-cell activation by targeting NF-κB, NFAT and AP-1 signaling pathways

scientific article published on 2 June 2011

Resveratrol potently reduces prostaglandin E2 production and free radical formation in lipopolysaccharide-activated primary rat microglia

scientific article (publication date: 10 October 2007)

SAR Studies on Curcumin’s Pro-inflammatory Targets: Discovery of Prenylated Pyrazolocurcuminoids as Potent and Selective Novel Inhibitors of 5-Lipoxygenase

scientific article published on 24 June 2014

STAT-3 Inhibitory Bisabolanes from Carthamus glaucus

scientific article published on 06 February 2012

SWATH proteomic profiling of prostate cancer cells identifies NUSAP1 as a potential molecular target for Galiellalactone

scientific article published on 25 October 2018

Solution- and solid-phase synthesis and anti-HIV activity of maslinic acid derivatives containing amino acids and peptides.

scientific article

Synergistic Activation of Latent HIV-1 Expression by Novel Histone Deacetylase Inhibitors and Bryostatin-1.

scientific article

Synthesis and biological evaluation of 12-aminoacylphorboids.

scientific article published in March 2010

Synthesis of structurally simplified analogues of aplidinone A, a pro-apoptotic marine thiazinoquinone.

scientific article

TRPV1 (vanilloid receptor, capsaicin receptor) agonists and antagonists

Tetrahydrocannabinolic acid is a potent PPARγ agonist with neuroprotective activity.

scientific article

The 5-HT3 receptor antagonist tropisetron inhibits T cell activation by targeting the calcineurin pathway.

scientific article published in August 2005

The 73 kDa subunit of the CPSF complex binds to the HIV-1 LTR promoter and functions as a negative regulatory factor that is inhibited by the HIV-1 Tat protein.

scientific article

The CB1/VR1 agonist arvanil induces apoptosis through an FADD/caspase-8-dependent pathway

scientific article published on 6 October 2003

The CD26 antigen is coupled to protein tyrosine phosphorylation and implicated in CD16-mediated lysis in natural killer cells

scientific article published on 01 April 1993

The Expression of the Ubiquitin Ligase SIAH2 (Seven In Absentia Homolog 2) Is Increased in Human Lung Cancer

scientific article published on 18 November 2015

The anti-inflammatory effects of the 5-HT₃ receptor antagonist tropisetron are mediated by the inhibition of p38 MAPK activation in primary human monocytes.

scientific article published on June 2012

The cannabinoid quinol VCE-004.8 alleviates bleomycin-induced scleroderma and exerts potent antifibrotic effects through peroxisome proliferator-activated receptor-γ and CB2 pathways

scientific article published on 18 February 2016

The effect of intensification with raltegravir on the HIV-1 reservoir of latently infected memory CD4 T cells in suppressed patients.

scientific article published in September 2012

The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders

scientific article published on 20 August 2018

The fungal metabolite galiellalactone interferes with the nuclear import of NF-κB and inhibits HIV-1 replication

scientific article published on 11 March 2014

The growth inhibitory activity of the Cimicifuga racemosa extract Ze 450 is mediated through estrogen and progesterone receptors-independent pathways.

scientific article published on March 2006

Transmission Electron Microscopy as Key Technique for the Characterization of Telocytes.

scientific article published on 6 March 2015

Tricyclic pyrazoles. Part 8. Synthesis, biological evaluation and modelling of tricyclic pyrazole carboxamides as potential CB2 receptor ligands with antagonist/inverse agonist properties

scientific article published on 6 February 2016

Turmeric Sesquiterpenoids: Expeditious Resolution, Comparative Bioactivity, and a New Bicyclic Turmeronoid

scientific article published on 20 January 2016

Tyrosine protein phosphorylation is required for protein kinase C-mediated proliferation in T cells

scientific article published on February 1991

VCE-003.2, a novel cannabigerol derivative, enhances neuronal progenitor cell survival and alleviates symptomatology in murine models of Huntington's disease.

scientific article published on 19 July 2016

VCE-004.3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPARγ- and CB2 receptor-dependent pathways

scientific article published on 23 August 2018

VCE-004.8, A Multitarget Cannabinoquinone, Attenuates Adipogenesis and Prevents Diet-Induced Obesity

scientific article published in Scientific Reports

Vanilloid receptor-1 regulates neurogenic inflammation in colon and protects mice from colon cancer

scientific article published on 06 March 2012

Δ9-TETRAHYDROCANNABINOLIC ACID ALLEVIATES COLLAGEN-INDUCED ARTHRITIS: ROLE OF PPARγ AND CB1 RECEPTORS

scientific article published on 08 June 2020

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