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List of works by Ijeoma Uchegbu

A New Class of Amphiphilic Poly-l-lysine Based Polymers Forms Nanoparticles on Probe Sonication in Aqueous Media

A nano-enabled cancer-specific ITCH RNAi chemotherapy booster for pancreatic cancer.

scientific article published on 6 October 2014

A non-covalently cross-linked chitosan based hydrogel

scientific article

A prodrug nanoparticle approach for the oral delivery of a hydrophilic peptide, leucine(5)-enkephalin, to the brain

scientific article published on 18 May 2012

Abstract 4519: Lomustine nanoparticles are effective brain cancer treatments

article

Abstract 5527: Oral administration of a nano-enabled form of Met-Enkephalin peptide controls pancreatic cancer growth

Abstract 5530: Chitosan amphiphile nanoparticles reduced the myelosuppressive effects of lomustine: Table 1

Adverse drug events related to dosage forms and delivery systems

scientific article published on January 1996

Amphiphilic poly(L-amino acids) - new materials for drug delivery

scientific article published on 18 May 2012

Amphotericin B Formulations – The Possibility of Generic Competition

article

Anticancer drug delivery with transferrin targeted polymeric chitosan vesicles.

scientific article published on January 2004

Cancer and the blood-brain barrier: 'Trojan horses' for courses?

scientific article

Cancer-specific transgene expression mediated by systemic injection of nanoparticles

scientific article

Carbohydrate-based micelle clusters which enhance hydrophobic drug bioavailability by up to 1 order of magnitude

scientific article published in December 2006

Chapter 7.3. Drug Delivery Strategies: Nanostructures for Improved Brain Delivery

Chitosan amphiphile coating of peptide nanofibres reduces liver uptake and delivers the peptide to the brain on intravenous administration.

scientific article published on 5 November 2014

Chitosan amphiphiles provide new drug delivery opportunities

Chitosan based hydrogels for macromolecular drug delivery

scholarly article by L. Martin et al published September 1998 in Journal of Pharmacy and Pharmacology

Claw Amphiphiles with a Dendrimer Core: Nanoparticle Stability and Drug Encapsulation Are Directly Proportional to the Number of Digits

article published in 2013

Controls on Polymer Molecular Weight May Be Used To Control the Size of Palmitoyl Glycol Chitosan Polymeric Vesicles

Delivery of peptides to the blood and brain after oral uptake of quaternary ammonium palmitoyl glycol chitosan nanoparticles.

scientific article published on 21 May 2012

Dendrimer-Based Gene Delivery Systems: Administration Routes andIn VivoEvaluation

article

Dendrimers for gene therapy

article

Dendrimers in gene delivery

scientific article

Designing medical technology for resilience: integrating health economics and human factors approaches

scientific article published on 15 December 2017

Detecting polymeric nanoparticles with coherent anti-stokes Raman scattering microscopy in tissues exhibiting fixative-induced autofluorescence

Dextran-pegylated microparticles for enhanced cellular uptake of hydrophobic drugs

scientific article published on 16 February 2013

Direct in vivo evidence on the mechanism by which nanoparticles facilitate the absorption of a water insoluble, P-gp substrate

scientific article published on November 2016

Distribution, metabolism and tumoricidal activity of doxorubicin administered in sorbitan monostearate (Span 60) niosomes in the mouse

article

Drug Delivery Across the Blood–Brain Barrier

article

Drug delivery gels from palmitoyl glycol chitosan

Drug distribution and a pulmonary adverse effect of intraperitoneally administered doxorubicin niosomes in the mouse

article

EDITORIAL

scientific article published on 01 January 2019

EDITORIAL

EDITORIAL

EDITORIAL: Emerging Bio-inspired and Bio-Compatible Nanomaterials in 21st Century

scientific article published on 01 January 2018

Early Economic Evaluation of Diagnostic Technologies: Experiences of the NIHR Diagnostic Evidence Co-operatives

scientific article published on 26 September 2019

Editorial

Editorial

Editorial

Editorial

Editorial

Efficacy of DOPE/DC-cholesterol liposomes and GCPQ micelles as AZD6244 nanocarriers in a 3D colorectal cancer in vitro model

scientific article published on 20 January 2016

Enhanced Oral Absorption of Hydrophobic and Hydrophilic Drugs Using Quaternary Ammonium Palmitoyl Glycol Chitosan Nanoparticles

Erratum to “Quaternary ammonium palmitoyl glycol chitosan—a new polysoap for drug delivery”

scholarly article published in International Journal of Pharmaceutics

Erratum to: Methods for evaluating medical tests and biomarkers

scientific article published on 30 March 2017

Evaluation of generation 2 and 3 poly(propylenimine) dendrimers for the potential cellular delivery of antisense oligonucleotides targeting the epidermal growth factor receptor.

scientific article

Exploring uptake mechanisms of oral nanomedicines using multimodal nonlinear optical microscopy ⬇️

scholarly article by Natalie L. Garrett et al published 5 March 2012 in Journal of Biophotonics

Gene and Ribonucleic Acid Therapy

article

Gene delivery with synthetic (non viral) carriers.

scientific article

Gene transfer with three amphiphilic glycol chitosans--the degree of polymerisation is the main controller of transfection efficiency.

scientific article

Glucose-receptor MR imaging of tumors: study in mice with PEGylated paramagnetic niosomes

scientific article published on 27 February 2004

Glucose-targeted niosomes deliver vasoactive intestinal peptide (VIP) to the brain.

scientific article published in November 2004

Health economic burden that different wound types impose on the UK's National Health Service

scientific article published on 26 May 2016

Health economic burden that wounds impose on the National Health Service in the UK

scientific article

High-resolution 3D isotropic MR imaging of mouse flank tumours obtained in vivo with solenoid RF micro-coil.

scientific article published on 28 December 2007

Highly Hydrophilic Fused Aggregates (Microsponges) from a C12 Spermine Bolaamphiphile

Hydration forces as a tool for the optimization of core–shell nanoparticle vectors for cancer gene therapy

article

Imaging cortical vasculature with stimulated Raman scattering and two-photon photothermal lensing microscopy

article published in 2012

In silico modelling of drug-polymer interactions for pharmaceutical formulations

scientific article published on 2 June 2010

In vitro and in vivo gene transfer with poly(amino acid) vesicles.

scientific article published on December 2003

In vitro/in vivo characterisation of polyhedral niosomes

scientific article published on 01 June 1999

Introduction

Investigations into the in-vitro/in-vivo behaviour of polyhedral niosomes

Label-free imaging of polymeric nanomedicines using coherent anti-stokes Raman scattering microscopy

scholarly article by N. L. Garrett et al published 27 April 2012 in Journal of Raman Spectroscopy

Limiting the level of tertiary amines on polyamines leads to biocompatible nucleic acid vectors

scientific article

Liposomes encapsulating polymeric chitosan based vesicles — a vesicle in vesicle system for drug delivery

scientific article published on 01 April 2000

Lomustine Nanoparticles Enable Both Bone Marrow Sparing and High Brain Drug Levels - A Strategy for Brain Cancer Treatments

scientific article published on 22 February 2016

Low Molecular Weight Micelles

Methods for Evaluating Medical Tests and Biomarkers

article by Gowri Gopalakrishna et al published February 2017 in Diagnostic and Prognostic Research

Nanofiber-based delivery of therapeutic peptides to the brain

scientific article published on 10 January 2013

Nanomedicines and nanodiagnostics come of age.

scientific article

Nanomedicines in the treatment of brain tumors

scientific article published on 29 January 2018

Nanoparticulate peptide delivery exclusively to the brain produces tolerance free analgesia

scientific article published on 27 November 2017

Nanotechnology in Advanced Drug Delivery ⬇️

scientific article published on October 25, 2011

Niosomes and polymeric chitosan based vesicles bearing transferrin and glucose ligands for drug targeting.

scientific article

Niosomes containing N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin (PK1): effect of method of preparation and choice of surfactant on niosome characteristics and a preliminary study of body distribution

Non-ionic surfactant based vesicles (niosomes) in drug delivery

Non-ionic surfactant vesicle (niosome) phase transitions

Non-ionic surfactant vesicles (niosomes): Physical and pharmaceutical chemistry

Nose to brain delivery in rats: Effect of surface charge of rhodamine B labeled nanocarriers on brain subregion localization.

scientific article published on 18 March 2017

Optimisation of synthetic vector systems for cancer gene therapy - the role of the excess of cationic dendrimer under physiological conditions

scientific article published on January 2014

Oral Particle Uptake and Organ Targeting Drives the Activity of Amphotericin B Nanoparticles

article by Dolores R Serrano et al published 15 January 2015 in Molecular Pharmaceutics

Osmotic Behaviour of Polyhedral Non-ionic Surfactant Vesicles (Niosomes)

scientific article published on 01 June 1999

PEI-based vesicle-polymer hybrid gene delivery system with improved biocompatibility.

scientific article published on April 2004

Pharmaceutical and biological characterisation of a doxorubicin-polymer conjugate (PK1) entrapped in sorbitan monostearate Span 60 niosomes

Pharmaceutical nanotechnology: polymeric vesicles for drug and gene delivery

scientific article published on September 2006

Physical Characterisation and Long-Term Stability Studies on Quaternary Ammonium Palmitoyl Glycol Chitosan (GCPQ)—A New Drug Delivery Polymer

Polyamine aza-cyclic compounds demonstrate anti-proliferative activity in vitro but fail to control tumour growth in vivo

scientific article published on November 2010

Polyelectrolyte Nanoparticles with High Drug Loading Enhance the Oral Uptake of Hydrophobic Compounds

article by Woei Ping Cheng et al published May 2006 in Biomacromolecules

Polyhedral Non-ionic Surfactant Vesicles ⬇️

scientific article published on June 1, 1997

Polymer Based Gene Silencing: In Vitro Delivery of SiRNA.

scientific article published in January 2016

Polymeric Chitosan-based Vesicles for Drug Delivery ⬇️

scientific article published on 01 May 1998

Polymeric Nanoparticles

article from 2013

Polymeric amphiphile branching leads to rare nanodisc shaped planar self-assemblies

scientific article published on 9 August 2008

Polymers in Drug Delivery

Preferential liver gene expression with polypropylenimine dendrimers.

scientific article

Preliminary characterization of amino acid based polymeric vesicles for gene delivery

article

Preliminary characterization of novel amino acid based polymeric vesicles as gene and drug delivery agents

scientific article published on November 2000

Preparation and in vitro/in vivo evaluation of luteinizing hormone releasing hormone (LHRH)-loaded polyhedral and spherical/tubular niosomes.

scientific article published on January 1999

Quantification of beta-galactosidase activity after non-viral transfection in vivo.

scientific article published in August 2003

Quaternary ammonium palmitoyl glycol chitosan--a new polysoap for drug delivery.

scientific article

Self-Assembly of Cetyl Linear Polyethylenimine To Give Micelles, Vesicles, and Dense Nanoparticles

Size-tuneable Nanometric MRI Contrast Agents for the Imaging of Molecular Weight Dependent Transport Processes

Strategies to deliver peptide drugs to the brain

scientific article published on 21 March 2014

Sustained buccal delivery of the hydrophobic drug denbufylline using physically cross-linked palmitoyl glycol chitosan hydrogels

scientific article

Synthetic anticancer gene medicine exploits intrinsic antitumor activity of cationic vector to cure established tumors.

scientific article published on September 2005

T-shaped Peptide Amphiphiles Self Assemble into Nanofiber Networks

The British Pharmaceutical Conference 2009. 6-9 September 2009, Manchester, UK

scientific article published on 01 November 2009

The Effect of Monomers and of Micellar and Vesicular Forms of Non-ionic Surfactants (Solulan C24 and Solulan 16) on Caco-2 Cell Monolayers ⬇️

scientific article published on 01 June 1997

The Encapsulation of Bleomycin Within Chitosan Based Polymeric Vesicles Does Not Alter its Biodistribution

scientific article published on 01 April 2000

The Level of Hydrophobic Substitution and the Molecular Weight of Amphiphilic Poly-L-lysine-Based Polymers Strongly Affects Their Assembly into Polymeric Bilayer Vesicles

scientific article published in May 2001

The activity of doxorubicin niosomes against an ovarian cancer cell line and three in vivo mouse tumour models

scientific article

The complexation between novel comb shaped amphiphilic polyallylamine and insulin: towards oral insulin delivery

scientific article published on 16 April 2009

The effect of polymer architecture on the nano self-assemblies based on novel comb-shaped amphiphilic poly(allylamine)

article

The effect of processing variables on the physical characteristics of non-ionic surfactant vesicles (niosomes) formed from a hexadecyl diglycerol ether

scientific article published on 01 May 2000

The evaluation of crown ether based niosomes as cation containing and cation sensitive drug delivery systems

The lower-generation polypropylenimine dendrimers are effective gene-transfer agents.

scientific article published on July 2002

The molecular shape of poly(propylenimine) dendrimer amphiphiles has a profound effect on their self assembly

scientific article published in February 2010

The oral delivery of amphotericin B

scientific article published on 01 January 2013

The polyacrylic acid/modified chitosan capsules with tunable release of small hydrophobic probe and drug

The release of model macromolecules may be controlled by the hydrophobicity of palmitoyl glycol chitosan hydrogels

scientific article

Tumour gene expression from C12 spermine amphiphile gene delivery systems

scientific article

Unusual Enthalpy Driven Self Assembly at Room Temperature with Chitosan Amphiphiles

scientific article published on 01 January 2019

Vesicles Prepared from Synthetic Amphiphiles — Polymeric Vesicles and Niosomes

article

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