List of works - Clare Joanna Strachan

A minitablet formulation made from electrospun nanofibers.

scientific article

A theoretical and spectroscopic study of co-amorphous naproxen and indomethacin

scientific article

A theoretical and spectroscopic study of γ-crystalline and amorphous indometacin

scientific article published on 01 February 2007

Amino Acids as Co-amorphous Excipients for Simvastatin and Glibenclamide: Physical Properties and Stability

scientific article published on 04 June 2014

Amino acids as co-amorphous stabilizers for poorly water soluble drugs--Part 1: preparation, stability and dissolution enhancement

scientific article published on 26 March 2013

Amino acids as co-amorphous stabilizers for poorly water-soluble drugs--Part 2: molecular interactions.

scientific article published on 6 April 2013

Amorphous solid dispersions of piroxicam and Soluplus(®): Qualitative and quantitative analysis of piroxicam recrystallization during storage

article

Analysis of matrix dosage forms during dissolution testing using raman microscopy

scientific article published on 10 May 2011

Analysis of sustained-release tablet film coats using terahertz pulsed imaging

article

Application of terahertz pulsed imaging to analyse film coating characteristics of sustained-release coated pellets

scientific article published on 27 May 2013

Assessment of crystalline disorder in cryo-milled samples of indomethacin using atomic pair-wise distribution functions.

scientific article

Characterization of Temperature-Induced Phase Transitions in Five Polymorphic Forms of Sulfathiazole by Terahertz Pulsed Spectroscopy and Differential Scanning Calorimetry

article

Characterization of chitosan–magnesium aluminum silicate nanocomposite films for buccal delivery of nicotine

scientific article published on 05 January 2013

Characterization of the bulk properties of pharmaceutical solids using nonlinear optics--a review

scientific article

Characterizing the conversion kinetics of carbamazepine polymorphs to the dihydrate in aqueous suspension using Raman spectroscopy.

scientific article

Chemical imaging of oral solid dosage forms and changes upon dissolution using coherent anti-Stokes Raman scattering microscopy.

scientific article published in March 2009

Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions

article

Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen.

scientific article published on 15 August 2011

Coherent anti-Stokes Raman scattering (CARS) microscopy visualizes pharmaceutical tablets during dissolution.

scientific article published on 4 July 2014

Coherent anti-Stokes Raman scattering microscopy driving the future of loaded mesoporous silica imaging

scientific article published on 24 July 2014

Crystallization Kinetics of an Amorphous Pharmaceutical Compound Using Fluorescence-Lifetime-Imaging Microscopy

scientific article published on 04 April 2018

Determination of amorphous content in the pharmaceutical process environment

scientific article published on 01 February 2007

Differential scanning calorimetry predicts the critical quality attributes of amorphous glibenclamide

scientific article published on 18 August 2015

Direct Measurement of Amorphous Solubility

scientific article published on 14 May 2019

Direct comparison of low- and mid-frequency Raman spectroscopy for quantitative solid-state pharmaceutical analysis.

scientific article

Distribution of binder in granules produced by means of twin screw granulation.

scientific article published on 19 December 2013

Drug hydrate systems and dehydration processes studied by terahertz pulsed spectroscopy

scientific article published on 21 October 2006

Effect of different preparation methods on the dissolution behaviour of amorphous indomethacin

scientific article published on 14 October 2011

Elucidation of Compression-Induced Surface Crystallization in Amorphous Tablets Using Sum Frequency Generation (SFG) Microscopy

scientific article published on 13 October 2016

Emerging trends in the stabilization of amorphous drugs.

scientific article published on 28 April 2012

Establishing quantitative in-line analysis of multiple solid-state transformations during dehydration.

scientific article

Evaluating the effect of coating equipment on tablet film quality using terahertz pulsed imaging

scientific article published on 4 April 2013

Evaluation of vibrational spectroscopic methods to identify and quantify multiple adulterants in herbal medicines.

scientific article published on 16 February 2015

Fluorescence-suppressed time-resolved Raman spectroscopy of pharmaceuticals using complementary metal-oxide semiconductor (CMOS) single-photon avalanche diode (SPAD) detector.

scientific article published on 9 November 2015

Hyphenated spectroscopy as a polymorph screening tool

scientific article published on 13 February 2007

Image-Based Investigation: Biorelevant Solubility of α and γ Indomethacin

scientific article published on 04 March 2019

In situ amorphisation of indomethacin with Eudragit® E during dissolution

scientific article published on 18 September 2013

In situ dissolution analysis using coherent anti-Stokes Raman scattering (CARS) and hyperspectral CARS microscopy

article

Indomethacin: new polymorphs of an old drug

scientific article published on 30 October 2013

Influence of Polymorphic Form, Morphology, and Excipient Interactions on the Dissolution of Carbamazepine Compacts

scientific article published on 01 March 2007

Influence of postharvest processing and storage conditions on key antioxidants in pūhā (Sonchus oleraceusL.)

scientific article published on 12 February 2014

Influence of sample characteristics on quantification of carbamazepine hydrate formation by X-ray powder diffraction and Raman spectroscopy

scientific article published on 13 December 2006

Influence of structural variations on drug release from lipid/polyethylene glycol matrices.

scientific article published on 3 May 2009

Inhibition of surface crystallisation of amorphous indomethacin particles in physical drug–polymer mixtures

scientific article published on 03 September 2013

Insights into Caco-2 cell culture structure using coherent anti-Stokes Raman scattering (CARS) microscopy.

scientific article published on 11 March 2017

Interdependence of particle properties and bulk powder behavior of indomethacin in quench-cooled molten two-phase solid dispersions.

scientific article published on 24 February 2018

Investigating dehydration from compacts using terahertz pulsed, Raman, and near-infrared spectroscopy

scientific article

Investigating the principles of recrystallization from glyceride melts.

scientific article

Investigating the relationship between drug distribution in solid lipid matrices and dissolution behaviour using Raman spectroscopy and mapping.

scientific article published in March 2010

Investigation of properties and recrystallisation behaviour of amorphous indomethacin samples prepared by different methods

scientific article published on 21 December 2010

Investigation of protein distribution in solid lipid particles and its impact on protein release using coherent anti-Stokes Raman scattering microscopy

scientific article published on 3 November 2014

Investigation of the Formation Process of Two Piracetam Cocrystals during Grinding

scientific article published on 12 October 2011

Investigation of the phase separation of PNIPAM using infrared spectroscopy together with multivariate data analysis

Isomalt and its Diastereomer Mixtures as Stabilizing Excipients With Freeze-Dried Lactate Dehydrogenase.

scientific article published on 13 January 2018

Multimodal Nonlinear Optical Imaging for Sensitive Detection of Multiple Pharmaceutical Solid-State Forms and Surface Transformations.

scientific article published on 26 September 2017

Multimodal non-linear optical imaging for the investigation of drug nano-/microcrystal-cell interactions

scientific article published on 5 September 2015

Pharmaceutical applications of non-linear imaging.

scientific article published on 21 December 2010

Physical Stability of Freeze-Dried Isomalt Diastereomer Mixtures

scientific article

Polymer incorporation method affects the physical stability of amorphous indomethacin in aqueous suspension

scientific article published on 16 June 2015

Prediction of tablet film-coating thickness using a rotating plate coating system and NIR spectroscopy

scientific article published on 8 October 2008

Probing Pharmaceutical Mixtures during Milling: The Potency of Low-Frequency Raman Spectroscopy in Identifying Disorder.

scientific article published in November 2017

Qualitative in situ analysis of multiple solid-state forms using spectroscopy and partial least squares discriminant modeling

scientific article published on 01 July 2007

Quantification of binary polymorphic mixtures of ranitidine hydrochloride using NIR spectroscopy

Quantifying ternary mixtures of different solid-state forms of indomethacin by Raman and near-infrared spectroscopy.

scientific article published on 17 July 2007

Raman spectroscopy for quantitative analysis of pharmaceutical solids.

scientific article published on February 2007

Rational formulation development and in vitro assessment of SMEDDS for oral delivery of poorly water soluble drugs

scientific article published on 10 April 2012

Screening for differences in the amorphous state of indomethacin using multivariate visualization

scientific article published on 11 November 2006

Solid lipid extrudates as sustained-release matrices: the effect of surface structure on drug release properties.

scientific article published on 14 August 2008

Spectroscopic investigation and quantitation of polymorphism and crystallinity of pharmaceutical compounds ⬇️

2005 doctoral thesis by Clare Joanna Strachan at University of Otago

Studies on the lipase-induced degradation of lipid-based drug delivery systems. Part II - Investigations on the mechanisms leading to collapse of the lipid structure.

scientific article

Supersaturating drug delivery systems: The potential of co-amorphous drug formulations.

scientific article

Surface Stabilization and Dissolution Rate Improvement of Amorphous Compacts with Thin Polymer Coatings: Can We Have It All?

scientific article published on 25 February 2020

Tailor-made dissolution profiles by extruded matrices based on lipid polyethylene glycol mixtures.

scientific article

Temperature dependent terahertz pulsed spectroscopy of carbamazepine

Terahertz pulsed imaging as an advanced characterisation tool for film coatings--a review.

scientific article published on 06 April 2013

The Influence of Milling on the Dissolution Performance of Simvastatin.

scientific article published on 17 December 2010

The effect of surfactants on the dissolution behavior of amorphous formulations

scientific article published on 05 March 2016

The formation and physical stability of two-phase solid dispersion systems of indomethacin in supercooled molten mixtures with different matrix formers

scientific article published on 23 November 2016

The impact of surface- and nano-crystallisation on the detected amorphous content and the dissolution behaviour of amorphous indomethacin

scientific article published on 06 June 2012

The influence of various excipients on the conversion kinetics of carbamazepine polymorphs in aqueous suspension

article

Time-Gated Raman Spectroscopy for Quantitative Determination of Solid-State Forms of Fluorescent Pharmaceuticals

scientific article published on 19 March 2018

Tissue-specific study across the stem reveals the chemistry and transcriptome dynamics of birch bark

scientific article published on 07 March 2019

Towards characterization and identification of solid state pharmaceutical mixtures through second harmonic generation

scientific article published in April 2006

Two-step solid lipid extrusion as a process to modify dissolution behavior.

scientific article

Understanding Critical Quality Attributes for Nanocrystals from Preparation to Delivery

scientific article

Understanding dissolution and crystallization with imaging: a surface point of view

scholarly article by Dunja Novakovic et al published 24 September 2018 in Molecular Pharmaceutics

Understanding the solid-state behaviour of triglyceride solid lipid extrudates and its influence on dissolution.

scientific article published on 6 June 2008

Understanding the solid-state forms of fenofibrate--a spectroscopic and computational study

scientific article published on 12 June 2008

Unravelling the relationship between degree of disorder and the dissolution behavior of milled glibenclamide

scientific article published on 17 December 2013

Using terahertz pulsed spectroscopy to quantify pharmaceutical polymorphism and crystallinity

scientific article published in April 2005

Using terahertz pulsed spectroscopy to study crystallinity of pharmaceutical materials

Visualizing the conversion of carbamazepine in aqueous suspension with and without the presence of excipients: A single crystal study using SEM and Raman microscopy

scientific article published on 03 June 2006

List of works by Clare Joanna Strachan

A minitablet formulation made from electrospun nanofibers.

A theoretical and spectroscopic study of co-amorphous naproxen and indomethacin

A theoretical and spectroscopic study of γ-crystalline and amorphous indometacin

Amino Acids as Co-amorphous Excipients for Simvastatin and Glibenclamide: Physical Properties and Stability

Amino acids as co-amorphous stabilizers for poorly water soluble drugs--Part 1: preparation, stability and dissolution enhancement

Amino acids as co-amorphous stabilizers for poorly water-soluble drugs--Part 2: molecular interactions.

Amorphous solid dispersions of piroxicam and Soluplus(®): Qualitative and quantitative analysis of piroxicam recrystallization during storage

Analysis of matrix dosage forms during dissolution testing using raman microscopy

Analysis of sustained-release tablet film coats using terahertz pulsed imaging

Application of terahertz pulsed imaging to analyse film coating characteristics of sustained-release coated pellets

Assessment of crystalline disorder in cryo-milled samples of indomethacin using atomic pair-wise distribution functions.

Characterization of Temperature-Induced Phase Transitions in Five Polymorphic Forms of Sulfathiazole by Terahertz Pulsed Spectroscopy and Differential Scanning Calorimetry

Characterization of chitosan–magnesium aluminum silicate nanocomposite films for buccal delivery of nicotine

Characterization of the bulk properties of pharmaceutical solids using nonlinear optics--a review

Characterizing the conversion kinetics of carbamazepine polymorphs to the dihydrate in aqueous suspension using Raman spectroscopy.

Chemical imaging of oral solid dosage forms and changes upon dissolution using coherent anti-Stokes Raman scattering microscopy.

Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions

Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen.

Coherent anti-Stokes Raman scattering (CARS) microscopy visualizes pharmaceutical tablets during dissolution.

Coherent anti-Stokes Raman scattering microscopy driving the future of loaded mesoporous silica imaging

Crystallization Kinetics of an Amorphous Pharmaceutical Compound Using Fluorescence-Lifetime-Imaging Microscopy

Determination of amorphous content in the pharmaceutical process environment

Differential scanning calorimetry predicts the critical quality attributes of amorphous glibenclamide

Direct Measurement of Amorphous Solubility

Direct comparison of low- and mid-frequency Raman spectroscopy for quantitative solid-state pharmaceutical analysis.

Distribution of binder in granules produced by means of twin screw granulation.

Drug hydrate systems and dehydration processes studied by terahertz pulsed spectroscopy

Effect of different preparation methods on the dissolution behaviour of amorphous indomethacin

Elucidation of Compression-Induced Surface Crystallization in Amorphous Tablets Using Sum Frequency Generation (SFG) Microscopy

Emerging trends in the stabilization of amorphous drugs.

Establishing quantitative in-line analysis of multiple solid-state transformations during dehydration.

Evaluating the effect of coating equipment on tablet film quality using terahertz pulsed imaging

Evaluation of vibrational spectroscopic methods to identify and quantify multiple adulterants in herbal medicines.

Fluorescence-suppressed time-resolved Raman spectroscopy of pharmaceuticals using complementary metal-oxide semiconductor (CMOS) single-photon avalanche diode (SPAD) detector.

Hyphenated spectroscopy as a polymorph screening tool

Image-Based Investigation: Biorelevant Solubility of α and γ Indomethacin

In situ amorphisation of indomethacin with Eudragit® E during dissolution

In situ dissolution analysis using coherent anti-Stokes Raman scattering (CARS) and hyperspectral CARS microscopy

Indomethacin: new polymorphs of an old drug

Influence of Polymorphic Form, Morphology, and Excipient Interactions on the Dissolution of Carbamazepine Compacts

Influence of postharvest processing and storage conditions on key antioxidants in pūhā (Sonchus oleraceusL.)

Influence of sample characteristics on quantification of carbamazepine hydrate formation by X-ray powder diffraction and Raman spectroscopy

Influence of structural variations on drug release from lipid/polyethylene glycol matrices.

Inhibition of surface crystallisation of amorphous indomethacin particles in physical drug–polymer mixtures

Insights into Caco-2 cell culture structure using coherent anti-Stokes Raman scattering (CARS) microscopy.

Interdependence of particle properties and bulk powder behavior of indomethacin in quench-cooled molten two-phase solid dispersions.

Investigating dehydration from compacts using terahertz pulsed, Raman, and near-infrared spectroscopy

Investigating the principles of recrystallization from glyceride melts.

Investigating the relationship between drug distribution in solid lipid matrices and dissolution behaviour using Raman spectroscopy and mapping.

Investigation of properties and recrystallisation behaviour of amorphous indomethacin samples prepared by different methods

Investigation of protein distribution in solid lipid particles and its impact on protein release using coherent anti-Stokes Raman scattering microscopy

Investigation of the Formation Process of Two Piracetam Cocrystals during Grinding

Investigation of the phase separation of PNIPAM using infrared spectroscopy together with multivariate data analysis

Isomalt and its Diastereomer Mixtures as Stabilizing Excipients With Freeze-Dried Lactate Dehydrogenase.

Multimodal Nonlinear Optical Imaging for Sensitive Detection of Multiple Pharmaceutical Solid-State Forms and Surface Transformations.

Multimodal non-linear optical imaging for the investigation of drug nano-/microcrystal-cell interactions

Pharmaceutical applications of non-linear imaging.

Physical Stability of Freeze-Dried Isomalt Diastereomer Mixtures

Polymer incorporation method affects the physical stability of amorphous indomethacin in aqueous suspension

Prediction of tablet film-coating thickness using a rotating plate coating system and NIR spectroscopy

Probing Pharmaceutical Mixtures during Milling: The Potency of Low-Frequency Raman Spectroscopy in Identifying Disorder.

Qualitative in situ analysis of multiple solid-state forms using spectroscopy and partial least squares discriminant modeling

Quantification of binary polymorphic mixtures of ranitidine hydrochloride using NIR spectroscopy

Quantifying ternary mixtures of different solid-state forms of indomethacin by Raman and near-infrared spectroscopy.

Raman spectroscopy for quantitative analysis of pharmaceutical solids.

Rational formulation development and in vitro assessment of SMEDDS for oral delivery of poorly water soluble drugs

Screening for differences in the amorphous state of indomethacin using multivariate visualization

Solid lipid extrudates as sustained-release matrices: the effect of surface structure on drug release properties.

Spectroscopic investigation and quantitation of polymorphism and crystallinity of pharmaceutical compounds ⬇️

Studies on the lipase-induced degradation of lipid-based drug delivery systems. Part II - Investigations on the mechanisms leading to collapse of the lipid structure.

Supersaturating drug delivery systems: The potential of co-amorphous drug formulations.

Surface Stabilization and Dissolution Rate Improvement of Amorphous Compacts with Thin Polymer Coatings: Can We Have It All?

Tailor-made dissolution profiles by extruded matrices based on lipid polyethylene glycol mixtures.

Temperature dependent terahertz pulsed spectroscopy of carbamazepine

Terahertz pulsed imaging as an advanced characterisation tool for film coatings--a review.

The Influence of Milling on the Dissolution Performance of Simvastatin.

The effect of surfactants on the dissolution behavior of amorphous formulations

The formation and physical stability of two-phase solid dispersion systems of indomethacin in supercooled molten mixtures with different matrix formers

The impact of surface- and nano-crystallisation on the detected amorphous content and the dissolution behaviour of amorphous indomethacin