List of works - Meir Wilchek

A sensitive colorimetric determination of cyanuric chloride and its activated agarose immobilization resins

scientific article published in April 2017

A spectrophotometric assay for allicin, alliin, and alliinase (alliin lyase) with a chromogenic thiol: reaction of 4-mercaptopyridine with thiosulfinates

scientific article

Allicin inhibits SDF-1alpha-induced T cell interactions with fibronectin and endothelial cells by down-regulating cytoskeleton rearrangement, Pyk-2 phosphorylation and VLA-4 expression

scientific article

Allicin inhibits cell growth and induces apoptosis through the mitochondrial pathway in HL60 and U937 cells

scientific article published on 21 December 2007

Allicin stimulates lymphocytes and elicits an antitumor effect: a possible role of p21ras

scientific article published on 01 February 2004

Allicin up-regulates cellular glutathione level in vascular endothelial cells

scientific article

Allicin-induced decrease in formation of fatty streaks (atherosclerosis) in mice fed a cholesterol-rich diet

scientific article

Alliin lyase (alliinase) from garlic (Allium sativum): crystallization and preliminary X-ray characterization.

scientific article

Allylmercaptocaptopril: a new antihypertensive drug

scientific article

An Overview of Affinity Chromatography

article

Apoptotic killing of B-chronic lymphocytic leukemia tumor cells by allicin generated in situ using a rituximab-alliinase conjugate.

scientific article published in February 2005

Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester

scientific article

Crystal structure of rhizavidin: insights into the enigmatic high-affinity interaction of an innate biotin-binding protein dimer

scientific article

DNA condensation by high-affinity interaction with avidin.

scientific article published in November 2004

Dimer-Tetramer Transition between Solution and Crystalline States of Streptavidin and Avidin Mutants

scientific article

Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis

scientific article published on 24 March 2004

Epitope Identification of Specific Naturally Occurring Human Anti-avidin Antibodies

scientific article published on 22 November 2017

Essentials of biorecognition: the (strept)avidin-biotin system as a model for protein-protein and protein-ligand interaction

scientific article

High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability

scientific article published on 20 April 2005

Inhibition of tumor growth by a novel approach: in situ allicin generation using targeted alliinase delivery.

scientific article

Ligand exchange between proteins. Exchange of biotin and biotin derivatives between avidin and streptavidin

scientific article

Modification of histidine (B10) is the causative agent for a superactive form of insulin

scientific article published in January 2002

Mutation of the important Tyr-33 residue of chicken avidin: functional and structural consequences

scientific article published on January 2003

My life with affinity

scientific article published on November 2004

Oriented versus random protein immobilization

scientific article

Rational design of an active avidin monomer.

scientific article published on 27 November 2002

Reaction mechanisms of allicin and allyl-mixed disulfides with proteins and small thiol molecules

scientific article published on 21 January 2010

Structural elements responsible for conversion of streptavidin to a pseudoenzyme

scientific article

Structure-based rational design of streptavidin mutants with pseudo-catalytic activity

scientific article

The antiatherogenic effect of allicin: possible mode of action.

scientific article

The effects of S-allylmercaptocaptopril, the synthetic product of allicin and captopril, on cardiovascular risk factors associated with the metabolic syndrome

scientific article

The effects of allicin on weight in fructose-induced hyperinsulinemic, hyperlipidemic, hypertensive rats

scientific article

Thiol-disulfide organization in alliin lyase (alliinase) from garlic (Allium sativum)

scientific article

Two structures of alliinase from Alliium sativum L.: apo form and ternary complex with aminoacrylate reaction intermediate covalently bound to the PLP cofactor

scientific article

List of works by Meir Wilchek

A sensitive colorimetric determination of cyanuric chloride and its activated agarose immobilization resins

A spectrophotometric assay for allicin, alliin, and alliinase (alliin lyase) with a chromogenic thiol: reaction of 4-mercaptopyridine with thiosulfinates

Allicin inhibits SDF-1alpha-induced T cell interactions with fibronectin and endothelial cells by down-regulating cytoskeleton rearrangement, Pyk-2 phosphorylation and VLA-4 expression

Allicin inhibits cell growth and induces apoptosis through the mitochondrial pathway in HL60 and U937 cells

Allicin stimulates lymphocytes and elicits an antitumor effect: a possible role of p21ras

Allicin up-regulates cellular glutathione level in vascular endothelial cells

Allicin-induced decrease in formation of fatty streaks (atherosclerosis) in mice fed a cholesterol-rich diet

Alliin lyase (alliinase) from garlic (Allium sativum): crystallization and preliminary X-ray characterization.

Allylmercaptocaptopril: a new antihypertensive drug

An Overview of Affinity Chromatography

Apoptotic killing of B-chronic lymphocytic leukemia tumor cells by allicin generated in situ using a rituximab-alliinase conjugate.

Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester

Crystal structure of rhizavidin: insights into the enigmatic high-affinity interaction of an innate biotin-binding protein dimer

DNA condensation by high-affinity interaction with avidin.

Dimer-Tetramer Transition between Solution and Crystalline States of Streptavidin and Avidin Mutants

Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis

Epitope Identification of Specific Naturally Occurring Human Anti-avidin Antibodies

Essentials of biorecognition: the (strept)avidin-biotin system as a model for protein-protein and protein-ligand interaction

High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability

Inhibition of tumor growth by a novel approach: in situ allicin generation using targeted alliinase delivery.

Ligand exchange between proteins. Exchange of biotin and biotin derivatives between avidin and streptavidin

Modification of histidine (B10) is the causative agent for a superactive form of insulin

Mutation of the important Tyr-33 residue of chicken avidin: functional and structural consequences

My life with affinity

Oriented versus random protein immobilization

Rational design of an active avidin monomer.

Reaction mechanisms of allicin and allyl-mixed disulfides with proteins and small thiol molecules

Structural elements responsible for conversion of streptavidin to a pseudoenzyme

Structure-based rational design of streptavidin mutants with pseudo-catalytic activity

The antiatherogenic effect of allicin: possible mode of action.

The effects of S-allylmercaptocaptopril, the synthetic product of allicin and captopril, on cardiovascular risk factors associated with the metabolic syndrome

The effects of allicin on weight in fructose-induced hyperinsulinemic, hyperlipidemic, hypertensive rats

Thiol-disulfide organization in alliin lyase (alliinase) from garlic (Allium sativum)

Two structures of alliinase from Alliium sativum L.: apo form and ternary complex with aminoacrylate reaction intermediate covalently bound to the PLP cofactor