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List of works by Nicolas Servant

A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis

scientific article

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

article

ACTuDB, a new database for the integrated analysis of array-CGH and clinical data for tumors.

scientific article

Adrenal GIPR expression and chromosome 19q13 microduplications in GIP-dependent Cushing's syndrome

scientific article published on 21 September 2017

Bioinformatics for precision medicine in oncology: principles and application to the SHIVA clinical trial

scientific article

Challenging single- and multi-probesets gene expression signatures of pathological complete response to neoadjuvant chemotherapy in breast cancer: experience of the REMAGUS 02 phase II trial

scientific article published on 2 October 2013

Changes in the organization of the genome during the mammalian cell cycle

scientific article published on 24 December 2013

Combinatorial code governing cellular responses to complex stimuli

scientific article published on 21 April 2015

Combinatorial flexibility of cytokine function during human T helper cell differentiation

scientific article published on 28 May 2014

Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass

scientific article

Correction: RNAi-Dependent and Independent Control of LINE1 Accumulation and Mobility in Mouse Embryonic Stem Cells

scientific article published on 14 May 2015

DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination

scientific article

Deep-sequencing protocols influence the results obtained in small-RNA sequencing

scientific article (publication date: 2012)

Design and statistical principles of the SHIVA trial

scientific article

Designs and challenges for personalized medicine studies in oncology: focus on the SHIVA trial.

scientific article

Developmental dynamics and disease potential of random monoallelic gene expression

scientific article published on February 2014

EMA - A R package for Easy Microarray data analysis

scientific article

EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells

scientific article published on 26 August 2019

Effective normalization for copy number variation in Hi-C data

scientific article published on 06 September 2018

Epigenomic alterations in breast carcinoma from primary tumor to locoregional recurrences.

scientific article

Genetic and epigenetic features direct differential efficiency of Xist-mediated silencing at X-chromosomal and autosomal locations

scientific article published on 25 September 2017

Goulphar: rapid access and expertise for standard two-color microarray normalization methods

scientific article published on 23 October 2006

HiC-Pro: an optimized and flexible pipeline for Hi-C data processing

scientific article

HiTC: exploration of high-throughput 'C' experiments

scientific article published on 24 August 2012

High-Resolution Mapping of DNA Breakpoints to Define True Recurrences Among Ipsilateral Breast Cancers

scientific article published on 25 December 2007

Highly dynamic and sex-specific expression of microRNAs during early ES cell differentiation

scientific article

Impaired PRC2 activity promotes transcriptional instability and favors breast tumorigenesis

scientific article

Importance of pre-analytical steps for transcriptome and RT-qPCR analyses in the context of the phase II randomised multicentre trial REMAGUS02 of neoadjuvant chemotherapy in breast cancer patients

scientific article

Independent transcriptional reprogramming and apoptosis induction by cisplatin

scientific article

Integration of a Radiosensitivity Molecular Signature Into the Assessment of Local Recurrence Risk in Breast Cancer

scientific article

Interactive analysis of single-cell epigenomic landscapes with ChromSCape

scientific article published on 11 November 2020

Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation.

scientific article

LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation

scientific article published in July 2016

LINE-1 activity in facultative heterochromatin formation during X chromosome inactivation

scientific article published on June 2010

Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation

scientific article

Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure.

scientific article

Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial

scientific article published on 02 September 2015

Multi-factor data normalization enables the detection of copy number aberrations in amplicon sequencing data

scientific article

Multiparametric analysis of cytokine-driven human Th17 differentiation reveals a differential regulation of IL-17 and IL-22 production

scientific article

PRC2 is dispensable for HOTAIR-mediated transcriptional repression

scientific article

Parental-to-embryo switch of chromosome organization in early embryogenesis

scientific article published on 25 March 2020

Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer

article

RNAi-dependent and independent control of LINE1 accumulation and mobility in mouse embryonic stem cells

scientific article

Randomised proof-of-concept phase II trial comparing targeted therapy based on tumour molecular profiling vs conventional therapy in patients with refractory cancer: results of the feasibility part of the SHIVA trial

scientific article

Search for a gene expression signature of breast cancer local recurrence in young women

scientific article published on 23 January 2012

Spatial partitioning of the regulatory landscape of the X-inactivation centre ⬇️

scientific article (publication date: 11 April 2012)

The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist

scientific article published on 27 May 2019

The spectrum of clinical trials aiming at personalizing medicine

scientific article published on June 2014

Treatment Algorithms Based on Tumor Molecular Profiling: The Essence of Precision Medicine Trials

scientific article

VAMP: visualization and analysis of array-CGH, transcriptome and other molecular profiles

scientific article published on 4 July 2006

Xist-dependent imprinted X inactivation and the early developmental consequences of its failure

scientific article published on 30 January 2017

[Biological network modelling and precision medicine in oncology]

scientific article published on 01 June 2014

iced: fast and memory efficient normalization of contact maps

scientific article published on 03 April 2019

miR-181a and miR-630 regulate cisplatin-induced cancer cell death

scientific article

ncPRO-seq: a tool for annotation and profiling of ncRNAs in sRNA-seq data

scientific article

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