Search filters

List of works by Gabriela da Silva Xavier

5'-AMP-activated protein kinase controls insulin-containing secretory vesicle dynamics

scientific article published on 7 October 2003

AMP- and stress-activated protein kinases: key regulators of glucose-dependent gene transcription in mammalian cells?

scientific article

ATP depletion inhibits Ca2+ release, influx and extrusion in pancreatic acinar cells but not pathological Ca2+ responses induced by bile

scientific article published on 20 October 2007

Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice

scientific article published on 21 June 2012

Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice

scientific article published on 17 October 2020

An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes ⬇️

scientific article published on September 14, 2011

Animal models of GWAS-identified type 2 diabetes genes

scientific article published on 11 April 2013

Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/HIF-1beta gene expression in pancreatic islet beta-cells

scientific article

Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon production

scientific article published on 24 June 2016

ChREBP binding to fatty acid synthase and L-type pyruvate kinase genes is stimulated by glucose in pancreatic beta-cells

scientific article published on 4 August 2006

ChREBP regulates Pdx-1 and other glucose-sensitive genes in pancreatic β-cells

scientific article

Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells

scientific journal article

Convolutional neural networks for reconstruction of undersampled optical projection tomography data applied to in vivo imaging of zebrafish

scientific article published on 29 August 2019

Correction: Transcription factor-7-like 2 () gene acts downstream of the kinase to control mTOR signaling, β cell growth, and insulin secretion

scientific article published in Journal of Biological Chemistry

Distinct roles for insulin and insulin-like growth factor-1 receptors in pancreatic beta-cell glucose sensing revealed by RNA silencing

scientific article published on January 2004

Divergent effects of liraglutide, exendin-4, and sitagliptin on beta-cell mass and indicators of pancreatitis in a mouse model of hyperglycaemia

scientific article

Down-regulation of vascular GLP-1 receptor expression in human subjects with obesity

scientific article published on 13 July 2018

Dynamic changes in cytosolic and mitochondrial ATP levels in pancreatic acinar cells

scientific article published on 25 January 2010

Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells

scientific article

Glucose is necessary for embryonic pancreatic endocrine cell differentiation.

scientific article published on 21 March 2007

Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells.

scientific article published on 9 September 2004

Imaging glucose-regulated insulin secretion and gene expression in single islet beta-cells: control by AMP-activated protein kinase

scientific article published in January 2004

Importin beta1 mediates the glucose-stimulated nuclear import of pancreatic and duodenal homeobox-1 in pancreatic islet beta-cells (MIN6).

scientific article published on February 2004

Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion

scientific article published on 23 October 2013

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants

scientific article

Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose

scientific article

LKB1 and AMPKα1 are required in pancreatic alpha cells for the normal regulation of glucagon secretion and responses to hypoglycemia

scientific article published on 31 January 2015

Metabolic and Functional Heterogeneity in Pancreatic β Cells

scientific article published on 13 August 2019

Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion

scientific article published on 10 February 2004

Mouse models of peripheral metabolic disease

scientific article published on 31 March 2018

Neuronatin regulates pancreatic β cell insulin content and secretion

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells.

scientific article

Nucleo-cytosolic shuttling of FoxO1 directly regulates mouse Ins2 but not Ins1 gene expression in pancreatic beta cells (MIN6).

scientific article published on 18 February 2011

Pancreatic alpha cell-selective deletion of Tcf7l2 impairs glucagon secretion and counter-regulatory responses to hypoglycaemia in mice.

scientific article published on 25 March 2017

Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization

scientific article

Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion

scientific journal article

Protein Kinases and Pancreatic Islet Function

article published in 2012

Reduced expression of TCF7L2 in adipocyte impairs glucose tolerance associated with decreased insulin secretion, incretins levels and lipid metabolism dysregulation in male mice

scientific article published on 20 May 2020

Regulation by Per-Arnt-Sim (PAS) kinase of pancreatic duodenal homeobox-1 nuclear import in pancreatic β-cells

scientific article published on 01 November 2006

Regulation of gene expression by glucose in pancreatic beta -cells (MIN6) via insulin secretion and activation of phosphatidylinositol 3'-kinase.

scientific article published on November 2000

Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression

scientific article published on May 2003

Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis

scientific article

Sarco(endo)plasmic reticulum ATPase is a molecular partner of Wolfram syndrome 1 protein, which negatively regulates its expression

scientific article published on 30 September 2014

Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.

scientific article published on 29 October 2014

Sodium-potassium ATPase 1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum protein involved in ER stress

scientific article

Stimulation of AMP-activated protein kinase is essential for the induction of drug metabolizing enzymes by phenobarbital in human and mouse liver

scientific article

Stimulation of acetyl-CoA carboxylase gene expression by glucose requires insulin release and sterol regulatory element binding protein 1c in pancreatic MIN6 beta-cells

scientific article published on August 2002

TCF7L2 controls insulin gene expression and insulin secretion in mature pancreatic beta-cells

scientific article published in June 2008

TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells

scientific article

The Cells of the Islets of Langerhans

scientific article published on 12 March 2018

Transcription factor-7-like 2 () gene acts downstream of the / kinase to control mTOR signaling, β cell growth, and insulin secretion

article

miR-29a and miR-29b Contribute to Pancreatic β-Cell-Specific Silencing of Monocarboxylate Transporter 1 (Mct1) ⬇️

scientific article published on June 6, 2011

Paulina is supported by:

About Paulina

Help