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List of works by Robert N Jorissen

A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data

scientific article

BRAF V600E Mutant Colorectal Cancer Subtypes Based on Gene Expression

scientific article published on 27 June 2016

BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities

scientific article

CR1/CR2 interactions modulate the functions of the cell surface epidermal growth factor receptor.

scientific article published on 11 March 2004

Colorectal Cancer Cell Line Proteomes are Representative of Primary Tumors and Predict Drug Sensitivity

scientific article

Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer

scientific article published on 22 April 2014

DNA copy-number alterations underlie gene expression differences between microsatellite stable and unstable colorectal cancers

scientific article published on December 2008

Defective Myb Function Ablates Cyclin E1 Expression and Perturbs Intestinal Carcinogenesis.

scientific article published on May 2015

Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis.

scientific article published on 22 October 2012

Epidermal growth factor receptor: mechanisms of activation and signalling.

scientific article

Evaluation of the transferability of survival calculators for stage II/III colon cancer across healthcare systems

scientific article published on 20 January 2019

Identification of a determinant of epidermal growth factor receptor ligand-binding specificity using a truncated, high-affinity form of the ectodomain.

scientific article

Immunoscore-has it scored for colon cancer precision medicine?

scientific article published on 01 November 2018

Impact of regular aspirin use on overall and cancer-specific survival in patients with colorectal cancer harboring a PIK3CA mutation

scientific article published on 31 December 2014

Incidence and predictors of common bile duct stones in patients with acute cholecystitis: a systematic literature review and meta-analysis

scientific article published on 19 November 2019

KRAS Mutation Is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer

scientific article published on 14 January 2011

Lymphocytic response to tumour and deficient DNA mismatch repair identify subtypes of stage II/III colorectal cancer associated with patient outcomes.

scientific article

MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors

scientific article published on 07 June 2018

Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer

scientific article

Modeling the epidermal growth factor -- epidermal growth factor receptor l2 domain interaction: implications for the ligand binding process

scientific article published in June 2002

Nonsense mediated decay resistant mutations are a source of expressed mutant proteins in colon cancer cell lines with microsatellite instability

scientific article

Optimizing targeted therapeutic development: analysis of a colorectal cancer patient population with the BRAF(V600E) mutation

scientific article published in May 2011

PHLDA1 expression marks the putative epithelial stem cells and contributes to intestinal tumorigenesis.

scientific article

PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in colorectal cancer

scientific article published on 30 April 2013

Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.

scientific article published on 30 September 2014

Quantitative threefold allele-specific PCR (QuanTAS-PCR) for highly sensitive JAK2 V617F mutant allele detection

scientific article

Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer

scientific article published on 26 April 2016

SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer

scientific article

Stoichiometry, kinetic and binding analysis of the interaction between epidermal growth factor (EGF) and the extracellular domain of the EGF receptor

scientific article published on 01 January 2000

Structural elements and allosteric mechanisms governing regulation and catalysis of CSK-family kinases and their inhibition of Src-family kinases

scientific article published on October 2010

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations

scientific article published on 17 September 2013

The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors

scientific article (publication date: February 2003)

The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma

scientific article published on 18 August 2015

Virtual screening of molecular databases using a support vector machine.

scientific article published in May 2005

Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer

scientific article

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