List of works by Carl Kirkpatrick

1063Estimating Health Outcomes of Antiviral Use in Influenza (flu) Outbreaks by Linking PK/PD and Epidemiology via Transmission Dynamic Model: A Novel Approach.

scientific article published in December 2014

1715Oseltamivir use in an Influenza Outbreak: Linking Pharmacology to Pharmacoeconomics.

scientific article published in December 2014

A Regression Approach to Visual Predictive Checks for Population Pharmacometric Models

scientific article published on 10 September 2018

A call for the appropriate application of clinical pharmacological principles in the search for safe and efficacious COVID-19 (SARS-COV-2) treatments

scientific article published on 08 June 2020

A dosing algorithm for metformin based on the relationships between exposure and renal clearance of metformin in patients with varying degrees of kidney function.

scientific article published on 28 April 2017

A systematic review of medication exposure assessment in prospective cohort studies of community dwelling older australians

scientific article published on 24 April 2015

A time-to-event pharmacodynamic model describing treatment response in patients with pulmonary tuberculosis using days to positivity in automated liquid mycobacterial culture

scientific article published on 26 November 2012

Adverse Drug Reactions Associated With Cholinesterase Inhibitors-Sequence Symmetry Analyses Using Prescription Claims Data

scientific article published on 31 December 2016

Aminoglycoside dosage regimens after therapeutic drug monitoring

scientific article published on 01 January 2002

An Observational Analysis of Medication Use During 5,727 Medical Emergency Team Activations at a Tertiary Referral Hospital

scientific article published on 23 April 2019

An analysis of allele, genotype and phenotype frequencies, actionable pharmacogenomic (PGx) variants and phenoconversion in 5408 Australian patients genotyped for CYP2D6, CYP2C19, CYP2C9 and VKORC1 genes

scientific article published on 06 September 2018

An educational intervention to improve vancomycin prescribing and monitoring

scientific article published on 10 January 2013

An extended interval dosing method for gentamicin in neonates

scientific article published on 01 December 2001

Analgesic use before and after oral anticoagulant initiation--a population-based study in Finland

scientific article published on 26 April 2015

Analysis of population pharmacokinetic data using NONMEM and WinBUGS.

scientific article

Antibiotic dosing in the 'at risk' critically ill patient: Linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients

scientific article

Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?

scientific article published on 21 October 2014

Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?

scientific article

Balancing evidence and social responsibility when targeting clinical pharmacy services: the example of people with intellectual disabilities

scientific article published on 24 April 2015

Beneficial hemodynamic, endocrine, and renal effects of urocortin in experimental heart failure: comparison with normal sheep

scientific article published in October 2002

Beta-lactam allergy in adults with cystic fibrosis.

scientific article published on 19 December 2006

Characterising the Transmission Dynamics of Acinetobacter baumannii in Intensive Care Units Using Hidden Markov Models

scientific article published on July 2015

Cimetidine does not appear to influence the distribution of metformin into human milk

scientific article published on 9 June 2008

Clinical Challenges of Tacrolimus for Maintenance Immunosuppression Post-Lung Transplantation

scientific article published in November 2017

Clinical Pharmacokinetics of Metformin

scientific article

Clinical medication review in Australia: A systematic review

scientific article published on 9 July 2015

Clinically relevant concentrations of fosfomycin combined with polymyxin B, tobramycin or ciprofloxacin enhance bacterial killing of Pseudomonas aeruginosa, but do not suppress the emergence of fosfomycin resistance.

scientific article published on 26 April 2016

Comparative Plasma and Cerebrospinal Fluid Pharmacokinetics of Paracetamol After Intravenous and Oral Administration

scientific article published on September 2016

Comparing 3 methods of monitoring gentamicin concentrations in patients with febrile neutropenia.

scientific article published in October 2011

Comparison of 2 weight-based heparin dosing nomograms in neurology and vascular surgical patients.

scientific article published on February 2015

Comparison of the probability of target attainment of anidulafungin against Candida spp. in patients with acute leukaemia.

scientific article published on 6 September 2014

Comparison of two Bayesian approaches to dose-individualization for once-daily aminoglycoside regimens

scientific article published on February 1997

Cost-Utility Analysis of Optimal Dosing of Oseltamivir Under Pandemic Influenza Using a Novel Approach: Linking Health Economics and Transmission Dynamic Models

scientific article

Cost-utility analysis of antiviral use under pandemic influenza using a novel approach - linking pharmacology, epidemiology and heath economics.

scientific article published on 15 February 2018

Defibrotide for the management of sinusoidal obstruction syndrome in patients who undergo haemopoietic stem cell transplantation

scientific article

Defibrotide for the treatment of sinusoidal obstruction syndrome: evaluation of response to therapy and patient outcomes.

scientific article published on 11 October 2017

Determination of para-aminohippuric acid (PAH) in human plasma and urine by liquid chromatography-tandem mass spectrometry.

scientific article published on 29 August 2009

Developing a Framework for Objective Structured Clinical Examinations Using the Nominal Group Technique

scientific article

Development of a sufficient design for estimation of fluconazole pharmacokinetics in people with HIV infection.

scientific article published on 28 June 2008

Diagnostic accuracy of cystatin C compared to serum creatinine for the estimation of renal dysfunction in adults and children--a meta-analysis

scientific article

Differences in suppression of regrowth and resistance despite similar initial bacterial killing for meropenem and piperacillin/tazobactam against Pseudomonas aeruginosa and Escherichia coli.

scientific article published on 3 January 2018

Disruptive innovation in community pharmacy - Impact of automation on the pharmacist workforce.

scientific article published on 14 May 2016

Dosing in obesity: a simple solution to a big problem.

scientific article published in November 2007

Drug-induced QT prolongation and torsades de pointes: evaluation of a QT nomogram.

scientific article published on 19 September 2007

Effect of Perioperative Opioids on Cancer-Relevant Circulating Parameters: Mu Opioid Receptor and Toll-Like Receptor 4 Activation Potential, and Proteolytic Profile.

scientific article published on 6 March 2018

Effect of different renal function on antibacterial effects of piperacillin against Pseudomonas aeruginosa evaluated via the hollow-fibre infection model and mechanism-based modelling.

scientific article published on 26 May 2016

Effects of Changes in Number of Medications and Drug Burden Index Exposure on Transitions Between Frailty States and Death: The Concord Health and Ageing in Men Project Cohort Study.

scientific article published on January 2016

Eight years' experience of an extended-interval dosing protocol for gentamicin in neonates.

scientific article published on 19 March 2009

Encouraging the move towards predictive population models for the obese using propofol as a motivating example

scientific article

Estimation of lean body weight in older women with hip fracture.

scientific article published in February 2012

Evaluation of a pharmacist-led penicillin allergy de-labelling ward round: a novel antimicrobial stewardship intervention

scientific article published on 01 June 2019

Evaluation of limited sampling methods for estimation of tacrolimus exposure in adult kidney transplant recipients

scientific article

Fifteen years of drug information in Christchurch Hospital

scientific article published on 01 September 2001

First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis

scientific article published on 16 December 2009

Free mycophenolic acid should be monitored in renal transplant recipients with hypoalbuminemia.

scientific article

Genetic polymorphism and outcomes with azathioprine and 6-mercaptopurine

scientific article published on 01 December 2000

Identification of major factors in Australian primary care pharmacists.

scientific article published on 16 September 2016

Impact of a Virtual Dementia Experience on Medical and Pharmacy Students’ Knowledge and Attitudes Toward People with Dementia: A Controlled Study

scientific article published on 01 January 2018

Impact of high-flux haemodialysis on the probability of target attainment for oral amoxicillin/clavulanic acid combination therapy.

scientific article published on 11 May 2017

Improving vancomycin prescription in critical illness through a drug use evaluation process: a weight-based dosing intervention study.

scientific article

In vitro pharmacodynamics of fosfomycin against clinical isolates of Pseudomonas aeruginosa.

scientific article published on 24 July 2015

Informative study designs to identify true parameter-covariate relationships.

scientific article published on 27 March 2009

Inhibition of flucloxacillin tubular renal secretion by piperacillin

scientific article

Interdisciplinary pharmacometrics linking oseltamivir pharmacology, influenza epidemiology and health economics to inform antiviral use in pandemics.

scientific article published on 20 February 2017

Lean body mass normalizes the effect of obesity on renal function.

scientific article published on 15 February 2008

Lithium in Paediatric Patients with Bipolar Disorder: Implications for Selection of Dosage Regimens via Population Pharmacokinetics/Pharmacodynamics.

scientific article published in January 2017

Measurement of total phospholipids in urine of patients treated with gentamicin

scientific article

Mechanism-based model of parasite growth and dihydroartemisinin pharmacodynamics in murine malaria

scientific article published on 12 November 2012

Medication Use and Fall-Related Hospital Admissions from Long-Term Care Facilities: A Hospital-Based Case-Control Study

scientific article published on June 2017

Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution.

scientific article published on 27 April 2009

Metformin therapy and diabetes in pregnancy

scientific article published on 01 August 2004

Metformin therapy in patients with chronic kidney disease.

scientific article

Modeling the impact of interventions against Acinetobacter baumannii transmission in intensive care units.

scientific article published on 07 August 2015

Modelling the time course of antimalarial parasite killing: a tour of animal and human models, translation and challenges

scientific article

Monte Carlo simulations: maximizing antibiotic pharmacokinetic data to optimize clinical practice for critically ill patients.

scientific article

Nurse-initiated pre-prescribed antibiotic orders to facilitate prompt and appropriate antibiotic administration in febrile neutropenia

scientific article published on 07 January 2020

Once daily aminoglycoside therapy. Is it less toxic than multiple daily doses and how should it be monitored?

scientific article

Once-daily aminoglycoside therapy: potential ototoxicity

scientific article published on 01 April 1997

Optimization and evaluation of piperacillin plus tobramycin combination dosage regimens against Pseudomonas aeruginosa for patients with altered pharmacokinetics via the hollow-fiber infection model and mechanism-based modeling

scientific article published on 20 February 2018

Optimizing hospital infection control: the role of mathematical modeling.

scientific article

Optimizing vancomycin dosage regimens in relation to high-flux haemodialysis

scientific article published on 01 January 2019

Oral Paracetamol Versus Combination Oral Analgesics for Acute Musculoskeletal Injuries

scientific article published on 02 August 2019

Patterns of use and appropriateness of antibiotics prescribed to patients receiving haemodialysis: an observational study

scientific article

Pharmacist-led medication review in community settings: An overview of systematic reviews.

scientific article published on 28 August 2016

Pharmacokinetic modeling and simulation of biweekly subcutaneous immunoglobulin dosing in primary immunodeficiency.

scientific article

Pharmacokinetic-pharmacodynamic rationale for cefepime dosing regimens in intensive care units.

scientific article

Pharmacokinetics and safety of oseltamivir in patients with end-stage renal disease treated with automated peritoneal dialysis

scientific article

Pharmacokinetics of gentamicin in 957 patients with varying renal function dosed once daily.

scientific article

Pharmacokinetics of piperacillin and tazobactam in plasma and subcutaneous interstitial fluid in critically ill patients receiving continuous venovenous haemodiafiltration

scientific article published on 10 February 2014

Pharmacometrics in Australasia-Twenty Years of Population Approach Group of Australia and New Zealand

scientific article published on 16 September 2019

Physiologically based pharmacokinetic modeling at the extremes of age.

scientific article published on 21 November 2012

Pilot study to determine the ability of health-care professionals to undertake drug dose calculations.

scientific article published in June 2004

Pitfalls of using estimations of glomerular filtration rate in an intensive care population

scientific article published on 01 July 2011

Plan S: A threat to quality of science?

scientific article published in Science

Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients

scientific article published on 20 January 2015

Population pharmacokinetics and pharmacodynamics of cefpirome in critically ill patients against Gram-negative bacteria

scientific article published on 07 March 2007

Population pharmacokinetics and pharmacodynamics of ofloxacin in South African patients with multidrug-resistant tuberculosis

scientific article

Population pharmacokinetics of fluconazole in critically ill patients receiving continuous venovenous hemodiafiltration: using Monte Carlo simulations to predict doses for specified pharmacodynamic targets

scientific article published on 19 September 2011

Population pharmacokinetics of metformin in healthy subjects and patients with type 2 diabetes mellitus: simulation of doses according to renal function

scientific article published in May 2013

Predicting the parasite killing effect of artemisinin combination therapy in a murine malaria model

scientific article published on 28 April 2014

Prevalence and Variability in Medications Contributing to Polypharmacy in Long-Term Care Facilities

scientific article published on 6 November 2017

Prevalence and factors associated with polypharmacy in long-term care facilities: a systematic review.

scientific article published on 11 April 2015

Primary antifungal prophylaxis in adult patients with acute lymphoblastic leukaemia: a multicentre audit.

scientific article

Principles and clinical application of assessing alterations in renal elimination pathways.

scientific article published on January 2003

Prioritizing interventions to manage polypharmacy in Australian aged care facilities

scientific article published on 15 June 2016

Qualitative evaluation of how a virtual dementia experience impacts medical and pharmacy students' self-reported knowledge and attitudes towards people with dementia

scientific article published on 16 April 2018

Quality Use of Medicines--medication safety issues in naming; look-alike, sound-alike medicine names.

scientific article published on 18 May 2012

Quantitative justification for target concentration intervention--parameter variability and predictive performance using population pharmacokinetic models for aminoglycosides.

scientific article published in July 2004

Rapid and simple high-performance liquid chromatographic assay for the determination of metformin in human plasma and breast milk

scientific article published in January 2002

Rates of PRN Medication Administration in Australian Residential Aged Care

scientific article published on 28 June 2020

Reducing Medical Admissions into Hospital through Optimising Medicines (REMAIN HOME) Study: protocol for a stepped-wedge, cluster-randomised trial

scientific article published on 13 April 2017

Respiratory syncytial virus-A dynamics and the effects of lumicitabine, a nucleoside viral replication inhibitor, in experimentally infected humans

scientific article published on 01 February 2019

Resveratrol Does Not Benefit Patients With Nonalcoholic Fatty Liver Disease

scientific article published on 25 February 2014

Resveratrol--pills to replace a healthy diet?

scientific article

Safe disposal of prescribed medicines

scientific article

Science fiction has become reality: Best practice for future viral pandemics

scientific article published on 23 July 2021

Single or multiple daily doses of aminoglycosides. Exposure to aminoglycosides should be monitored during treatment

scientific article published in August 1996

Spontaneously reported haemorrhagic adverse events associated with rivaroxaban and dabigatran in Australia

scientific article

Stability of benzylpenicillin during continuous home intravenous therapy

scientific article published on 10 March 2004

Substantial Impact of Altered Pharmacokinetics in Critically Ill Patients on the Antibacterial Effects of Meropenem Evaluated via the Dynamic Hollow-Fiber Infection Model

scientific article published on 6 March 2017

Systematic review and meta-analysis of oral paracetamol versus combination oral analgesics for acute musculoskeletal injuries

scientific article published on 31 August 2020

Target concentration intervention in oncology: where are we at?

scientific article published on June 2012

The Reporting Of MEdication use in Observational studies (ROMEO) Statement

scientific article published on 9 May 2015

The dosing and monitoring of vancomycin: what is the best way forward?

scientific article published on 29 December 2018

The frequency and nature of clinician identified medication-related rapid response system calls

scientific article published on 11 October 2019

The impact of frailty on pharmacokinetics in older people: using gentamicin population pharmacokinetic modeling to investigate changes in renal drug clearance by glomerular filtration

scientific article published on 14 February 2014

The pharmacokinetics of metformin and concentrations of haemoglobin A1C and lactate in Indigenous and non-Indigenous Australians with type 2 diabetes mellitus

scientific article

The pharmacokinetics of oxypurinol in people with gout

scientific article

The role of medication advisory committees in residential aged care services

scientific article published on 28 January 2020

The therapeutic monitoring of antimicrobial agents

scientific article

The use of a change in gentamicin clearance as an early predictor of gentamicin-induced nephrotoxicity

scientific article published in October 2003

Therapeutic value of orally administered silibinin in renal cell carcinoma: manipulation of insulin-like growth factor binding protein-3 levels

scientific article published on 01 August 2007

Transfer of metformin into human milk

scientific article

Understanding how medications contribute to clinical deterioration and are used in rapid response systems: A comprehensive scoping review

scientific article published on 11 July 2018

Unifying a profession and a health care system: Building the case for a "one pharmacy" global community

scientific article published on 25 April 2019

Using in silico viral kinetic models to guide therapeutic strategies during a pandemic: An example in SARS-CoV-2

scientific article published on 29 December 2020

Using population pharmacokinetics to determine gentamicin dosing during extended daily diafiltration in critically ill patients with acute kidney injury

scientific article

Vancomycin dosing in chronic high-flux haemodialysis - a systematic review.

scientific article published on 25 December 2017

Why is polypharmacy increasing in aged care facilities? The views of Australian health care professionals.

scientific article