List of works by Muredach P. Reilly

A Simple Test of Class-Level Genetic Association Can Reveal Novel Cardiometabolic Trait Loci

scientific article published on 9 February 2016

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

scientific article

A functional synonymous coding variant in the IL1RN gene is associated with survival in septic shock.

scientific article

A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex

scientific article published on 7 February 2012

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease

scientific article

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

scientific article

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

scientific article

A guide to genome-wide association analysis and post-analytic interrogation

scientific article published on 6 September 2015

A human model of inflammatory cardio-metabolic dysfunction; a double blind placebo-controlled crossover trial

scientific article

A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis

scientific article published on 03 May 2009

A score test for genetic class-level association with nonlinear biomarker trajectories.

scientific article published on 23 May 2017

A study of aspirin and clopidogrel in idiopathic pulmonary arterial hypertension

scientific article (publication date: March 2006)

ABO Blood Group as a Model for Platelet Glycan Modification in Arterial Thrombosis

scientific article published on 4 June 2015

ABO Blood Groups and Cardiovascular Diseases

scientific article

ABO blood type A is associated with increased risk of ARDS in whites following both major trauma and severe sepsis

scientific article published on April 2014

ASEP: Gene-based detection of allele-specific expression cross individuals in a population by RNA sequencing

scientific article published on 11 May 2020

Abnormal lipoprotein particles and cholesterol efflux capacity in patients with psoriasis

scientific article published on 21 July 2012

Activation of innate immunity modulates insulin sensitivity, glucose effectiveness and pancreatic β-cell function in both African ancestry and European ancestry healthy humans

scientific article

Adipocyte modulation of high-density lipoprotein cholesterol.

scientific article

Adipokines, insulin resistance, and coronary artery calcification

scientific article

Adipose genes down-regulated during experimental endotoxemia are also suppressed in obesity

scientific article

Adipose inflammation, insulin resistance, and cardiovascular disease

scientific article

Adipose modulation of high-density lipoprotein cholesterol: implications for obesity, high-density lipoprotein metabolism, and cardiovascular disease.

scientific article published on October 2011

Adipose tissue RNASeq reveals novel gene-nutrient interactions following n-3 PUFA supplementation and evoked inflammation in humans

scientific article published on 11 January 2016

Adipose tissue modulation of HDL

An inflammatory cascade leading to hyperresistinemia in humans

scientific article

Anti-inflammatory effects of high-density lipoprotein through activating transcription factor 3: benefit beyond cholesterol transport-dependent processes

scientific article published on 17 April 2014

Apolipoprotein B but not LDL cholesterol is associated with coronary artery calcification in type 2 diabetic whites

scientific article published on 02 June 2009

Apolipoprotein E and coronary disease: a puzzling paradox

scientific article

Ascending and descending thoracic aorta calcification in type 2 diabetes mellitus

scientific article published on 16 May 2015

Association between Inflammation and Cardiac Geometry in Chronic Kidney Disease: Findings from the CRIC Study

scientific article published on 24 April 2015

Association between albuminuria, kidney function, and inflammatory biomarker profile in CKD in CRIC.

scientific article

Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis

scientific article published on 23 January 2013

Association of exome sequences with plasma C-reactive protein levels in >9000 participants

scientific article

Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks

scientific article

Association of lower plasma fetuin-a levels with peripheral arterial disease in type 2 diabetes

scientific article

Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification

scientific article

Associations among race/ethnicity, ApoC-III genotypes, and lipids in HIV-1-infected individuals on antiretroviral therapy

scientific article

Atheroprotective lipoprotein effects of a niacin-simvastatin combination compared to low- and high-dose simvastatin monotherapy

scientific article

Atherosclerotic cardiovascular disease risk in the HAART-treated HIV-1 population

scientific article

Balancing the benefits and risks of 2 doses of dabigatran compared with warfarin in atrial fibrillation

scientific article published on 13 June 2013

Bayesian variable selection for post-analytic interrogation of susceptibility loci

scientific article published on 17 November 2016

Bioactive products formed in humans from fish oils

scientific article

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Biosynthesis of 15-deoxy-delta12,14-PGJ2 and the ligation of PPARgamma

scientific article published in September 2003

C-Reactive Protein and Coronary Artery Calcification

scientific article published on 21 August 2003

C-reactive protein modifies the association of plasma leptin with coronary calcium in asymptomatic overweight individuals

scientific article published on 07 July 2011

CRISPR/Cas9-Mediated Gene Editing in Human iPSC-Derived Macrophage Reveals Lysosomal Acid Lipase Function in Human Macrophages-Brief Report

scientific article

CUBN is a gene locus for albuminuria

scientific article

CXCL12: a new player in coronary disease identified through human genetics

scientific article published on August 2010

CXCL16 is a marker of inflammation, atherosclerosis, and acute coronary syndromes in humans

scientific article (publication date: 30 January 2007)

Candidate gene association study of coronary artery calcification in chronic kidney disease: findings from the CRIC study (Chronic Renal Insufficiency Cohort).

scientific article published on 30 May 2013

Cardiac biomarkers are associated with an increased risk of stroke and death in patients with atrial fibrillation: a Randomized Evaluation of Long-term Anticoagulation Therapy (RE-LY) substudy

scientific article published on 28 February 2012

Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease

scientific article

Cardiovascular risk factors and mitral annular calcification in type 2 diabetes

scientific article published on 5 December 2012

Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study

scientific article

Cerebrovascular Emboli Related to Pulmonary Venous Thrombosis After Lung Transplantation

scientific article published on 01 March 1998

Changes in Renal Function in Patients With Atrial Fibrillation: An Analysis From the RE-LY Trial

scientific article published in June 2015

Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1.

scientific article published on 20 May 2015

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

scientific article published on 2 March 2016

Common and Rare Genetic Variation in CCR2, CCR5, or CX3CR1 and Risk of Atherosclerotic Coronary Heart Disease and Glucometabolic Traits

scientific article published on 24 March 2016

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

scientific article

Common variants in HSPB7 and FRMD4B associated with advanced heart failure

scientific article

Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer

scientific article

Comparison of Characteristics and Outcomes of Dabigatran Versus Warfarin in Hypertensive Patients With Atrial Fibrillation (from the RE-LY Trial).

scientific article published on 28 July 2015

Comparison of Coronary Artery Calcium Scores Between Patients With Psoriasis and Type 2 Diabetes

scientific article published on 24 August 2016

Comparison of Dabigatran and Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: The RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulant Therapy).

scientific article published on 05 August 2016

Comparison of high-density lipoprotein cholesterol to apolipoprotein A-I and A-II to predict coronary calcium and the effect of insulin resistance

scientific article

Comparison of matrix metalloproteinase 9 and brain natriuretic peptide as clinical biomarkers in chronic heart failure

scientific article published on 21 February 2008

Computed tomography-defined abdominal adiposity is associated with acute kidney injury in critically ill trauma patients*

scientific article

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

scientific article

Concomitant Oral Anticoagulant and Nonsteroidal Anti-Inflammatory Drug Therapy in Patients With Atrial Fibrillation

scientific article published on 09 July 2018

Concomitant use of antiplatelet therapy with dabigatran or warfarin in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial

scientific article published on 27 December 2012

Coronary Artery Calcification and Risk of Cardiovascular Disease and Death Among Patients With Chronic Kidney Disease

scientific article

Coronary Calcification in Chronic Kidney Disease: Morphology, Mechanisms and Mortality

scientific article published on 19 November 2009

Coronary artery calcification and cardiovascular risk factors: impact of the analytic approach

scientific article published in March 2004

Correcting population stratification in genetic association studies using a phylogenetic approach

scientific article

Cyclooxygenase inhibitors and the antiplatelet effects of aspirin

scientific article (publication date: 20 December 2001)

D-dimer and factor VIIa in atrial fibrillation - prognostic values for cardiovascular events and effects of anticoagulation therapy. A RE-LY substudy.

scientific article published on 28 January 2016

Dabigatran and warfarin in vitamin K antagonist-naive and -experienced cohorts with atrial fibrillation

scientific article

Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial

scientific article published on 6 November 2010

Dabigatran compared with warfarin in patients with atrial fibrillation and symptomatic heart failure: a subgroup analysis of the RE-LY trial

scientific article

Dabigatran etexilate and reduction in serum apolipoprotein B

scientific article published on 09 November 2015

Dabigatran versus warfarin in patients with atrial fibrillation

scientific article

Dabigatran versus warfarin in patients with atrial fibrillation: an analysis of patients undergoing cardioversion

scientific article published on 03 January 2011

Dabigatran versus warfarin: effects on ischemic and hemorrhagic strokes and bleeding in Asians and non-Asians with atrial fibrillation

scientific article published on 06 June 2013

Dabigatran with or without concomitant aspirin compared with warfarin alone in patients with nonvalvular atrial fibrillation (PETRO Study).

scientific article published on 17 August 2007

De novo RNA sequence assembly during in vivo inflammatory stress reveals hundreds of unannotated lincRNAs in human blood CD14+ monocytes and in adipose tissue

scientific article published on 7 April 2017

Deep RNA Sequencing Uncovers a Repertoire of Human Macrophage Long Intergenic Noncoding RNAs Modulated by Macrophage Activation and Associated With Cardiometabolic Diseases

scientific article published on 13 November 2017

Dense genotyping of candidate gene loci identifies variants associated with high-density lipoprotein cholesterol

scientific article published on 8 February 2011

Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls

scientific article

Dietary isoflavone intake is associated with evoked responses to inflammatory cardiometabolic stimuli and improved glucose homeostasis in healthy volunteers

scientific article

Differential association of plasma angiopoietin-like proteins 3 and 4 with lipid and metabolic traits

scientific article

Differential associations of oral glucose tolerance test-derived measures of insulin sensitivity and pancreatic β-cell function with coronary artery calcification and microalbuminuria in type 2 diabetes.

scientific article published on 15 August 2013

Discovery and refinement of loci associated with lipid levels

scientific article

Distinct functions of PPARγ isoforms in regulating adipocyte plasticity

scientific article published on 3 November 2016

Distribution and medical impact of loss-of-function variants in the Finnish founder population

scientific article

Dysfunctional nitric oxide signalling increases risk of myocardial infarction

scientific article published on 10 November 2013

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

Effects of Niacin, Statin, and Fenofibrate on Circulating Proprotein Convertase Subtilisin/Kexin Type 9 Levels in Patients With Dyslipidemia

scientific article published on 31 October 2014

Effects of metformin and leuprolide acetate on insulin resistance and testosterone levels in nondiabetic postmenopausal women: a randomized, placebo-controlled trial

scientific article

Effects of pioglitazone on lipoproteins, inflammatory markers, and adipokines in nondiabetic patients with metabolic syndrome

scientific article

Efficacy and safety of dabigatran compared to warfarin in patients with paroxysmal, persistent, and permanent atrial fibrillation: results from the RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) study

scientific article published on 01 February 2012

Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial

scientific article

Efficacy and safety of dabigatran compared with warfarin in patients with atrial fibrillation in relation to renal function over time-A RE-LY trial analysis

scientific article published on 05 January 2018

Efficacy and safety of dabigatran compared with warfarin in relation to baseline renal function in patients with atrial fibrillation: a RE-LY (Randomized Evaluation of Long-term Anticoagulation Therapy) trial analysis

scientific article published on 09 December 2013

Efficacy and safety of dabigatran vs. warfarin in patients with atrial fibrillation--sub-analysis in Japanese population in RE-LY trial.

scientific article published on 19 March 2011

Emerging diagnostic and therapeutic molecular imaging applications in vascular disease

scientific article

Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis

scientific article

Endothelial lipase is increased in vivo by inflammation in humans

scientific article published on 22 January 2008

Evaluating the association between all components of the metabolic syndrome and pre-eclampsia.

scientific article published in June 2009

Evaluating the impact of sequencing depth on transcriptome profiling in human adipose

scientific article

Exome sequencing and directed clinical phenotyping diagnose cholesterol ester storage disease presenting as autosomal recessive hypercholesterolemia

scientific article published on 26 September 2013

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

scientific article

Experimental endotoxemia induces adipose inflammation and insulin resistance in humans

scientific article

Expression of Calgranulin Genes S100A8, S100A9 and S100A12 Is Modulated by n-3 PUFA during Inflammation in Adipose Tissue and Mononuclear Cells

scientific article

Fibroblast growth factor 23 is not associated with and does not induce arterial calcification

scientific article published on 6 February 2013

Fractalkine is a novel human adipochemokine associated with type 2 diabetes

scientific article published on May 2011

Frequency, risk factors, and clinical outcomes of left ventricular assist device-associated ventricular thrombus

article

From Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary Disease

scientific article published on February 2016

Functional analysis and transcriptomic profiling of iPSC-derived macrophages and their application in modeling Mendelian disease

scientific article

Gender differences in the association of C-reactive protein with coronary artery calcium in type-2 diabetes

scientific article

Gene profiling of human adipose tissue during evoked inflammation in vivo

scientific article published on 06 July 2009

Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations

scientific article published on 17 December 2013

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

scientific article published on 20 February 2014

Genetic association for renal traits among participants of African ancestry reveals new loci for renal function

scientific article

Genetic basis of atherosclerosis: insights from mice and humans

scientific article

Genetic determinants of dabigatran plasma levels and their relation to bleeding

scientific article

Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium

scientific article published on 2 February 2012

Genetic determinants of warfarin maintenance dose and time in therapeutic treatment range: a RE-LY genomics substudy

scientific article published on 4 August 2016

Genetic predisposition to higher blood pressure increases coronary artery disease risk

scientific article published on 11 March 2013

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

scientific article published on 23 September 2010

Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk

scientific article

Genetic variation in the Major Histocompatibility Complex and association with depression

Genetically determined height and coronary artery disease

scientific article

Genetics of coronary artery calcification among African Americans, a meta-analysis

scientific article

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.

scientific article published on 26 April 2018

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

scientific article

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

scientific article

Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele

scientific article published on 18 July 2011

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

scientific journal article

Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease

scientific article

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project

scientific article

Genome-wide interrogation reveals hundreds of long intergenic noncoding RNAs that associate with cardiometabolic traits

scientific article published on 10 June 2016

GlycA Is a Novel Biomarker of Inflammation and Subclinical Cardiovascular Disease in Psoriasis.

scientific article published on 21 September 2016

Growth-differentiation factor 15 and risk of major bleeding in atrial fibrillation: Insights from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial

scientific article

HDL proteomics: pot of gold or Pandora's box?

scientific article published on March 2007

High-Density Lipoprotein Proteomic Composition, and not Efflux Capacity, Reflects Differential Modulation of Reverse Cholesterol Transport by Saturated and Monounsaturated Fat Diets

article

Higher order lipase gene association with plasma triglycerides

article

Higher plasma CXCL12 levels predict incident myocardial infarction and death in chronic kidney disease: findings from the Chronic Renal Insufficiency Cohort study

scientific article

Higher serum testosterone concentration in older women is associated with insulin resistance, metabolic syndrome, and cardiovascular disease

scientific article published on 21 October 2009

Human Induced Pluripotent Stem Cell-Derived Macrophages for Unraveling Human Macrophage Biology

scientific article published on 5 October 2017

Human experimental endotoxemia in modeling the pathophysiology, genomics, and therapeutics of innate immunity in complex cardiometabolic diseases

scientific article published on 30 December 2014

IRF2BP2: A New Player at the Crossroads of Inflammation and Lipid Metabolism

scientific article published on September 2015

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

scientific article

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

scientific article published on 4 September 2017

Identification of seven loci affecting mean telomere length and their association with disease

scientific article published on April 2013

Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk

scientific article

Importance of evaluating cell cholesterol influx with efflux in determining the impact of human serum on cholesterol metabolism and atherosclerosis

scientific article

Importance of persistent elevation of cardiac biomarkers in atrial fibrillation: a RE-LY substudy

scientific article published on 2 May 2014

Improvement in insulin sensitivity after human islet transplantation for type 1 diabetes.

scientific article published on October 2013

Inactivating mutations in NPC1L1 and protection from coronary heart disease

scientific article

Increased formation of distinct F2 isoprostanes in hypercholesterolemia.

scientific article published in December 1998

Inflammation and Arterial Stiffness in Chronic Kidney Disease: Findings From the CRIC Study

scientific article published on April 2017

Inflammation and vascular remodeling

scientific article published on 13 November 2012

Inflammation impairs reverse cholesterol transport in vivo.

scientific article published on 16 February 2009

Inflammation induces fibrinogen nitration in experimental human endotoxemia

scientific article

Inflammation modulates human HDL composition and function in vivo.

scientific article

Innate immunity modulates adipokines in humans.

scientific article published on 20 March 2007

Insulin sensitivity index in type 1 diabetes and following human islet transplantation: comparison of the minimal model to euglycemic clamp measures

scientific article

Integrative genomics identifies 7p11.2 as a novel locus for fever and clinical stress response in humans

scientific article

Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.

scientific article

Interferon gamma attenuates insulin signaling, lipid storage, and differentiation in human adipocytes via activation of the JAK/STAT pathway.

scientific article

Interleukin-6 Is a Risk Factor for Atrial Fibrillation in Chronic Kidney Disease: Findings from the CRIC Study

scientific article published on 3 February 2016

Interleukin-6 and C-reactive protein and risk for death and cardiovascular events in patients with atrial fibrillation

scientific article

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

scientific article published on 14 March 2012

Intracranial hemorrhage in atrial fibrillation patients during anticoagulation with warfarin or dabigatran: the RE-LY trial

scientific article

Knockout of Adamts7, a novel coronary artery disease locus in humans, reduces atherosclerosis in mice

scientific article

LIPA Variants in Genome-Wide Association Studies of Coronary Artery Diseases: Loss-of-Function or Gain-of-Function?

scientific article published in June 2017

Labeling monocytes with gold nanoparticles to track their recruitment in atherosclerosis with computed tomography

scientific article published on 9 February 2016

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

scientific article

Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci.

scientific article

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

scientific article

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

scientific article

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

scientific article

Leptin and incident cardiovascular disease: the Multi-ethnic Study of Atherosclerosis (MESA).

scientific article

Leptin resistance: a possible interface of inflammation and metabolism in obesity-related cardiovascular disease

scientific article

Lipoprotein(a) and Risk of Myocardial Infarction and Death in Chronic Kidney Disease: Findings From the CRIC Study (Chronic Renal Insufficiency Cohort).

scientific article published on 24 August 2017

Lipoprotein(a) is strongly associated with coronary artery calcification in type-2 diabetic women

scientific article

Loci influencing blood pressure identified using a cardiovascular gene-centric array

scientific article published on 8 January 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

scientific article

Long-term evaluation of dabigatran 150 vs. 110 mg twice a day in patients with non-valvular atrial fibrillation

scientific article published on 03 March 2016

Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

scientific article published on May 2017

Loss-of-function DNA sequence variant in the CLCNKA chloride channel implicates the cardio-renal axis in interindividual heart failure risk variation

scientific article

Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans

scientific article published on 16 March 2009

MDR and PRP: A Comparison of Methods for High-Order Genotype-Phenotype Associations

Major Gastrointestinal Bleeding Often Is Caused by Occult Malignancy in Patients Receiving Warfarin or Dabigatran to Prevent Stroke and Systemic Embolism From Atrial Fibrillation

scientific article

Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-analysis.

scientific article published on 19 August 2009

Measurement of waist circumference predicts coronary atherosclerosis beyond plasma adipokines

article

Measures of insulin resistance add incremental value to the clinical diagnosis of metabolic syndrome in association with coronary atherosclerosis

scientific article

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

scientific article

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

scientific article

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

scientific article published on 11 September 2011

Metabolic Effects of CX3CR1 Deficiency in Diet-Induced Obese Mice

scientific article

Metabolic syndrome, components, and cardiovascular disease prevalence in chronic kidney disease: findings from the Chronic Renal Insufficiency Cohort (CRIC) Study

scientific article

Mixed modeling of meta-analysis P-values (MixMAP) suggests multiple novel gene loci for low density lipoprotein cholesterol

scientific article

Mixed modelling to characterize genotype–phenotype associations

article

Monocyte mayhem: do subtypes modulate distinct atherosclerosis phenotypes?

scientific article published in February 2012

MultiGeMS: detection of SNVs from multiple samples using model selection on high-throughput sequencing data.

scientific article

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

scientific article (publication date: 17 September 2013)

Myocardial ischemic events in patients with atrial fibrillation treated with dabigatran or warfarin in the RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) trial

scientific article published on 3 January 2012

Newly identified events in the RE-LY trial

scientific article published on 01 November 2010

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis ⬇️

scientific article published on 12 October 2016

Non-compressible arterial disease and the risk of coronary calcification in type-2 diabetes

scientific article

Novel eicosapentaenoic acid-derived F3-isoprostanes as biomarkers of lipid peroxidation.

scientific article published on 11 June 2009

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Novel mechanistic links between high-protein diets and atherosclerosis

scientific article published on 01 January 2020

Occurrence of death and stroke in patients in 47 countries 1 year after presenting with atrial fibrillation: a cohort study

scientific article

Omega-3 PUFA supplementation and the response to evoked endotoxemia in healthy volunteers

scientific article

Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo

scientific article published on 4 August 2003

Overlap between common genetic polymorphisms underpinning kidney traits and cardiovascular disease phenotypes: the CKDGen consortium

scientific article published on 6 March 2013

PCSK9 is a critical regulator of the innate immune response and septic shock outcome.

scientific article

Pathway-Wide Association Study Implicates Multiple Sterol Transport and Metabolism Genes in HDL Cholesterol Regulation.

scientific article published on 5 July 2011

PennSeq: accurate isoform-specific gene expression quantification in RNA-Seq by modeling non-uniform read distribution

scientific article published on 20 December 2013

Perioperative bridging anticoagulation during dabigatran or warfarin interruption among patients who had an elective surgery or procedure. Substudy of the RE-LY trial.

scientific article published on 4 December 2014

Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) randomized trial

scientific article published on 14 June 2012

Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo

scientific article published on 19 December 2005

Pharmacology of the receptors for the phorbol ester tumor promoters

scientific article published on 01 November 2000

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

scientific article (publication date: 11 August 2012)

Plasma Leptin Levels Are Associated with Coronary Atherosclerosis in Type 2 Diabetes

scientific article published on 01 August 2004

Plasma apolipoprotein C-III levels, triglycerides, and coronary artery calcification in type 2 diabetics

scientific article

Plasma cytokines, metabolic syndrome, and atherosclerosis in humans.

scientific article published in January 2007

Plasma lipoprotein(a) levels are associated with mild renal impairment in type 2 diabetics independent of albuminuria

scientific article

Psoriasis is associated with decreased plasma adiponectin levels independently of cardiometabolic risk factors.

scientific article published on January 2014

Quantitative high performance liquid chromatography/tandem mass spectrometric analysis of the four classes of F(2)-isoprostanes in human urine

scientific article published on November 1999

RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies

scientific article

Race and gender variation in response to evoked inflammation

scientific article published on 12 March 2013

Race modifies the association between adiposity and inflammation in patients with chronic kidney disease: findings from the chronic renal insufficiency cohort study

scientific article

Rationale and design of RE-LY: randomized evaluation of long-term anticoagulant therapy, warfarin, compared with dabigatran

scientific article published in May 2009

Reasons for hospitalization and risk of mortality in patients with atrial fibrillation treated with dabigatran or warfarin in the Randomized Evaluation of Long-term Anticoagulation Therapy (RE-LY) trial

scientific article published on 01 July 2019

Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

article

Relation of atherogenic lipoproteins with estimated glomerular filtration rate decline: a longitudinal study

scientific article published on 4 August 2015

Relation of plasma fatty acid binding proteins 4 and 5 with the metabolic syndrome, inflammation and coronary calcium in patients with type-2 diabetes mellitus

scientific article

Relationship of estimated GFR and coronary artery calcification in the CRIC (Chronic Renal Insufficiency Cohort) Study

scientific article

Reply to Letters Regarding Article, “Risk of Bleeding With 2 Doses of Dabigatran Compared With Warfarin in Older and Younger Patients With Atrial Fibrillation: An Analysis of the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) Tria

Reply: Anticoagulant-Related Nephropathy

scientific article published on 01 December 2015

Reply: regarding the effect of dabigatran plasma concentrations

scientific article published on 07 May 2014

Resistin gene variation is associated with systemic inflammation but not plasma adipokine levels, metabolic syndrome or coronary atherosclerosis in nondiabetic Caucasians

scientific article

Resistin is an inflammatory marker of atherosclerosis in humans.

scientific article published on 14 February 2005

Response to letter regarding article, "Cardiac biomarkers are associated with an increased risk of stroke and death in patients with atrial fibrillation: a randomized evaluation of long-term anticoagulation therapy (RE-LY) substudy".

scientific article

Response to letter regarding article, "Efficacy and safety of dabigatran compared with warfarin in relation to baseline renal function in patients with atrial fibrillation: a RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) trial a

scientific article published on 01 November 2014

Response to letters regarding article, “Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Randomized Trial”.

scientific article published in March 2013

Ridge regression for longitudinal biomarker data.

scientific article published on 27 September 2011

Risk factors for coronary artery calcium among patients with chronic kidney disease (from the Chronic Renal Insufficiency Cohort Study).

scientific article

Risk factors for progression of coronary artery calcification in patients with chronic kidney disease: The CRIC study

scientific article published on 10 February 2018

Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: an analysis of the randomized evaluation of long-term anticoagulant therapy (RE-LY) trial

scientific article published on 16 May 2011

Risks for stroke, bleeding, and death in patients with atrial fibrillation receiving dabigatran or warfarin in relation to the CHADS2 score: a subgroup analysis of the RE-LY trial

scientific article published in November 2011

Runs of Homozygosity: Association with Coronary Artery Disease and Gene Expression in Monocytes and Macrophages

scientific article

Selective PKC beta inhibition with ruboxistaurin and endothelial function in type-2 diabetes mellitus

scientific article

Selective association of electrocardiographic abnormalities with insulin sensitivity and beta-cell function in type 2 diabetes mellitus: a cross-sectional analysis

scientific article published on 18 February 2016

Semiparametric odds ratio model for case-control and matched case-control designs

scientific article published on 11 January 2013

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

scientific article

Serum Fractalkine (CX3CL1) and Cardiovascular Outcomes and Diabetes: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study

scientific article published on 17 March 2015

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants

scientific article

Strong synaptic transmission impact by copy number variations in schizophrenia

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Synergistic Modulation of Inflammatory but not Metabolic Effects of High-Fat Feeding by CCR2 and CX3CR1.

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Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease ⬇️

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Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease

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Tetranor PGDM, an abundant urinary metabolite reflects biosynthesis of prostaglandin D2 in mice and humans.

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The ABO Histo-Blood Group and AKI in Critically Ill Patients with Trauma or Sepsis.

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The addition of niacin to statin therapy improves high-density lipoprotein cholesterol levels but not metrics of functionality

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The effect of dabigatran plasma concentrations and patient characteristics on the frequency of ischemic stroke and major bleeding in atrial fibrillation patients: the RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulation Therapy).

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The effects of nonselective non-aspirin non-steroidal anti-inflammatory medications on the risk of nonfatal myocardial infarction and their interaction with aspirin

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The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels

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The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

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Tobacco-Related Cardiovascular Diseases in the 21st Century

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Transcriptome-Wide Analysis Reveals Modulation of Human Macrophage Inflammatory Phenotype Through Alternative Splicing

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Translational studies of lipoprotein-associated phospholipase A₂ in inflammation and atherosclerosis

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Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies

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Very low density lipoprotein cholesterol associates with coronary artery calcification in type 2 diabetes beyond circulating levels of triglycerides

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