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List of works by Luigino Calzetta

A 6MWT index to predict O2 flow correcting exercise induced SpO2 desaturation in ILD.

scientific article published on 10 October 2013

A Systematic Review With Meta-Analysis of Dual Bronchodilation With LAMA/LABA for the Treatment of Stable COPD.

scientific article published on 25 February 2016

A pilot survey on the quality of life in respiratory rehabilitation carried out in COPD patients with severe respiratory failure: preliminary data of a novel Inpatient Respiratory Rehabilitation Questionnaire (IRRQ)

scientific article

A safety comparison of LABA+LAMA vs LABA+ICS combination therapy for COPD.

scientific article published on 5 March 2018

Aclidinium/formoterol fixed-dose combination for the treatment of chronic obstructive pulmonary disease.

scientific article

Adding a Second Bronchodilator in COPD: A Meta-Analysis on the Risk of Specific Cardiovascular Serious Adverse Events of Tiotropium/Olodaterol Fixed-Dose Combination

scientific article published on 06 April 2020

Advances in asthma drug discovery: evaluating the potential of nasal cell sampling and beyond

scientific article published on 22 April 2014

Advances in understanding of mechanisms related to increased cardiovascular risk in COPD

scientific article published on 21 October 2020

Anxiety and asthma in youth. Is a stress-induced increased cholinergic tone the possible link?

scientific article published on 29 November 2017

Assessing the viability of long-acting β2-agonists in paediatric asthma patients: a pharmacokinetic/pharmacodynamic perspective

scientific article published on 12 September 2016

Assessment of pet exposure by questionnaires in epidemiological studies (but also in clinical practice!): Why the questions should be simplified?

scientific article published on 23 June 2016

Asthma and COPD in an Italian adult population: role of BMI considering the smoking habit.

scientific article published on 20 May 2013

Asthma and comorbid medical illness.

scientific article published on 22 December 2010

Beclomethasone dipropionate, formoterol fumarate and glycopyrronium bromide: Synergy of triple combination therapy on human airway smooth muscle ex vivo

scientific article published on 29 January 2020

Brain natriuretic peptide modulates calcium homeostasis and epidermal growth factor receptor gene signalling in asthmatic airways smooth muscle cells

scientific article published on 23 February 2015

Brain natriuretic peptide protects against hyperresponsiveness of human asthmatic airway smooth muscle via an epithelial cell-dependent mechanism

scientific article published in March 2014

Brain natriuretic peptide: Much more than a biomarker.

scientific article

Can bronchial asthma with an highly prevalent airway (and systemic) vagal tone be considered an independent asthma phenotype? Possible role of anticholinergics.

scientific article published on 30 May 2016

Can pet keeping be considered the only criterion of exposure to cat/dog allergens in the first year of life?

scientific article published on 01 December 2015

Canakinumab for the treatment of chronic obstructive pulmonary disease.

scientific article published on 04 February 2015

Cardiovascular disease in asthma and COPD: A population-based retrospective cross-sectional study

scientific article published on 01 February 2012

Change in asthma and COPD prescribing by Italian general practitioners between 2006 and 2008.

scientific article published in September 2011

Chronic cat allergen exposure and low sensitization: Possible limitations in patient selection?

article by Gennaro Liccardi et al published May 2016 in The Journal of Allergy and Clinical Immunology

Chronic obstructive pulmonary disease and coronary disease: COPDCoRi, a simple and effective algorithm for predicting the risk of coronary artery disease in COPD patients

scientific article

Clinical effect of corticosteroids in asthma-affected horses: A quantitative synthesis.

scientific article published on 2 February 2018

Clinical efficacy of bronchodilators in equine asthma: Looking for minimal important difference

scientific article published on 01 July 2019

Combining long-acting bronchodilators with different mechanisms of action: A pharmacological approach to optimize bronchodilation of equine airways.

scientific article published on 26 March 2018

Contribution of sensory nerves to LPS-induced hyperresponsiveness of human isolated bronchi

scientific article published on 24 April 2015

Diabetes mellitus among outpatients with COPD attending a university hospital

scientific article published on 13 April 2014

Dog allergen immunotherapy and allergy to furry animals

scientific article published in June 2016

Dual LABA/LAMA bronchodilators in chronic obstructive pulmonary disease: why, when, and how.

scientific article published on 16 February 2018

Dual bronchodilatory and pulmonary anti-inflammatory activity of RO5024118, a novel agonist at vasoactive intestinal peptide VPAC2 receptors.

scientific article published on November 2010

Dysfunction of small airways and prevalence, airway responsiveness and inflammation in asthma: much more than small particle size of pet animal allergens

scientific article

Effect of the Mixed Phosphodiesterase 3/4 Inhibitor RPL554 on Human Isolated Bronchial Smooth Muscle Tone

scientific article published on 13 June 2013

Effects of chronic treatment with the new ultra-long-acting β2 -adrenoceptor agonist indacaterol alone or in combination with the β1 -adrenoceptor blocker metoprolol on cardiac remodelling

scientific article published on 12 May 2015

Effects of neuraminidase on equine isolated bronchi.

scientific article published on 26 February 2008

Efficacy and safety of RPL554, a dual PDE3 and PDE4 inhibitor, in healthy volunteers and in patients with asthma or chronic obstructive pulmonary disease: findings from four clinical trials

scientific article published on 25 October 2013

Efficacy and safety of triple combination therapy for treating chronic obstructive pulmonary disease: an expert review

scientific article published on 02 November 2020

Efficacy and safety profile of doxofylline compared to theophylline in asthma: a meta-analysis

scientific article published on 03 August 2019

Emerging anti-inflammatory strategies for COPD ⬇️

scientific article published on April 10, 2012

Emerging drugs for chronic obstructive pulmonary disease.

scientific article published on 16 February 2012

Ensifentrine (RPL554): an investigational PDE3/4 inhibitor for the treatment of COPD

scientific article published on 01 September 2019

Evaluating triple ICS/LABA/LAMA therapies for COPD patients: a network meta-analysis of ETHOS, KRONOS, IMPACT, and TRILOGY studies

scientific article published on 28 August 2020

Evaluation of fluticasone propionate/salmeterol for the treatment of COPD: a systematic review

scientific article published on 04 April 2020

Evaluation of the effects of the R- and S-enantiomers of salbutamol on equine isolated bronchi

scientific article published on 31 December 2010

Experimental Glucocorticoid Receptor Agonists for the Treatment of Asthma: A Systematic Review

scientific article published on 06 August 2020

Exploring the neural mechanisms of finasteride: a proteomic analysis in the nucleus accumbens

scientific article published on 06 October 2016

Gastroesophageal reflux and COPD exacerbations: Is cholinergic-mediated oesophago-bronchial reflex a possible link?

scientific article published on 16 September 2016

Glucagon-Like Peptide 1 Receptor: A Novel Pharmacological Target for Treating Human Bronchial Hyperresponsiveness.

scientific article published on 22 July 2016

High glucose enhances responsiveness of human airways smooth muscle via the Rho/ROCK pathway.

scientific article published on 31 May 2012

How does race/ethnicity influence pharmacological response to asthma therapies?

scientific article published on 12 March 2018

How many systemic reactions to skin prick tests could be preventable in defined conditions?

scientific article published on 01 February 2016

Immune sensitization of equine bronchus: glutathione, IL-1beta expression and tissue responsiveness.

scientific article

Influence of N-acetylcysteine on chronic bronchitis or COPD exacerbations: a meta-analysis

scientific article

Inhaled therapies and cardiovascular risk in patients with chronic obstructive pulmonary disease

scientific article published on 01 February 2019

Interaction between corticosteroids and muscarinic antagonists in human airways.

scientific article published on 30 November 2015

Investigational treatments in phase I and II clinical trials: a systematic review in chronic obstructive pulmonary disease (COPD)

scientific article published on 13 May 2020

Is Allergic Sensitization to Siberian Hamster Preventable in High-Risk Individuals Who Are Already Sensitized or Exposed to Furry Animals?

scientific article published in January 2016

LABA/LAMA combination in COPD: a meta-analysis on the duration of treatment

scientific article published on 17 January 2017

Long-Acting Muscarinic Antagonists Under Investigational to Treat Chronic Obstructive Pulmonary Disease

scientific article published on 08 December 2020

Monoclonal antibodies in severe asthma: is it worth it?

scientific article published on 23 May 2019

Multifaceted activity of N-acetyl-l-cysteine in chronic obstructive pulmonary disease

scientific article published on 17 July 2018

Novel and effective balanced intravenous-inhalant anaesthetic protocol in swine by using unrestricted drugs

scientific article

Olodaterol + tiotropium bromide for the treatment of COPD.

scientific article published on 19 February 2016

Onset of action of budesonide/formoterol Spiromax(®) compared with budesonide/formoterol Turbuhaler(®) in patients with COPD.

scientific article published on 22 June 2016

Optimizing de-escalation of inhaled corticosteroids in COPD: a systematic review of real-world findings

scientific article published on 04 September 2020

Optimizing drug delivery in COPD: The role of inhaler devices

scientific article

Optimizing the Development Strategy of Combination Therapy in Respiratory Medicine: From Isolated Airways to Patients

scientific article published on 25 October 2019

Oxidation pathway and exacerbations in COPD: the role of NAC.

scientific article

Partial nephrectomy using radiofrequency incremental bipolar generator with multi electrode probe: experimental study in bench pig kidneys.

scientific article

Pharmacodynamic and pharmacokinetic assessment of fluticasone furoate + vilanterol for the treatment of asthma.

scientific article published on 2 June 2016

Pharmacogenetic and pharmacogenomic considerations of asthma treatment.

scientific article published on 10 October 2017

Pharmacogenomic Response of Inhaled Corticosteroids for the Treatment of Asthma: Considerations for Therapy

scientific article published on 04 August 2020

Pharmacokinetic/pharmacodynamic drug evaluation of benralizumab for the treatment of asthma

scientific article published on 24 July 2017

Pharmacokinetic/pharmacodynamic profile of reslizumab in asthma.

scientific article published on 21 December 2017

Pharmacological assessment of the onset of action of aclidinium and glycopyrronium versus tiotropium in COPD patients and human isolated bronchi

scientific article published on 5 May 2015

Pharmacological characterisation of the interaction between glycopyrronium bromide and indacaterol fumarate in human isolated bronchi, small airways and bronchial epithelial cells

scientific article published on 13 June 2016

Pharmacological characterization of the interaction between aclidinium bromide and formoterol fumarate on human isolated bronchi.

scientific article published on 22 October 2014

Pharmacological characterization of the interaction between the dual phosphodiesterase (PDE) 3/4 inhibitor RPL554 and glycopyrronium on human isolated bronchi and small airways

scientific article published on 18 April 2015

Pharmacological characterization of the interaction between tiotropium and olodaterol administered at 5:5 concentration-ratio in equine bronchi.

scientific article published on 26 July 2017

Pharmacological interaction between LABAs and LAMAs in the airways: optimizing synergy.

scientific article published on 14 May 2015

Pharmacological investigation on the anti-oxidant and anti-inflammatory activity of N-acetylcysteine in an ex vivo model of COPD exacerbation

scientific article published on 24 January 2017

Pharmacological treatments in asthma-affected horses: A pair-wise and network meta-analysis.

scientific article

Pharmacology and Therapeutics of Bronchodilators ⬇️

scientific article published on May 18, 2012

Phosphodiesterase inhibitors for chronic obstructive pulmonary disease: what does the future hold?

scientific article

Pirfenidone, nintedanib and N-acetylcysteine for the treatment of idiopathic pulmonary fibrosis: A systematic review and meta-analysis

scientific article

Preclinical evaluation of an inhibitor of cytosolic phospholipase A2α for the treatment of asthma

scientific article

Propofol protects against opioid-induced hyperresponsiveness of airway smooth muscle in a horse model of target-controlled infusion anaesthesia.

scientific article published on 11 September 2015

Protein prenylation contributes to the effects of LPS on EFS-induced responses in human isolated bronchi

scientific article published on 28 January 2011

Reduced risk of COVID-19 hospitalization in asthmatic and COPD patients: a benefit of inhaled corticosteroids?

scientific article published on 12 November 2020

Safety Considerations with Dual Bronchodilator Therapy in COPD: An Update

scientific article published on 29 February 2016

Searching for the synergistic effect between aclidinium and formoterol: From bench to bedside.

scientific article published on 13 August 2015

Senolytic drugs in respiratory medicine: is it an appropriate therapeutic approach?

scientific article published on 04 July 2018

Severe Asthma and Biological Therapy: When, Which, and for Whom

scientific article published on 26 December 2019

TNF-alpha inhibitors in asthma and COPD: we must not throw the baby out with the bath water

scientific article published on 22 October 2009

The Challenges of Precision Medicine in COPD.

scientific article published on 28 February 2017

The Time Course of Pulmonary Function Tests in COPD Patients with Different Levels of Blood Eosinophils

scientific article published on 16 October 2016

The cardiovascular risk of tiotropium: is it real?

scientific article published on September 2010

The clinical use of regenerative therapy in COPD

scientific article

The discovery of roflumilast for the treatment of chronic obstructive pulmonary disease

scientific article published on 12 May 2016

The effect of indacaterol during an acute exacerbation of COPD

scientific article published on 08 April 2013

The influence of propofol, remifentanil and lidocaine on the tone of human bronchial smooth muscle

scientific article

The prevalence of asthma and COPD in Italy: a practice-based study

scientific article published on 15 October 2010

The role of triple therapy in the management of COPD

scientific article published on 27 June 2020

The safety of dual bronchodilation on cardiovascular serious adverse events in COPD

scientific article published on 14 May 2018

Therapeutic Monoclonal Antibodies for the Treatment of Chronic Obstructive Pulmonary Disease.

scientific article

Tiotropium formulations and safety: a network meta-analysis

scientific article published on 16 September 2016

Translational Study Searching for Synergy between Glycopyrronium and Indacaterol

scientific article published on 15 September 2014

Treatment of COPD: moving beyond the lungs.

scientific article published on 30 April 2012

Umeclidinium for the treatment of chronic obstructive pulmonary disease

scientific article

Use of ICS in COPD: From Blockbuster Medicine to Precision Medicine

scientific article

Use of indacaterol for the treatment of COPD: a pharmacokinetic evaluation.

scientific article published on 03 December 2013

β-Adrenoceptor modulation in chronic obstructive pulmonary disease: present and future perspectives.

scientific article published on October 2013

β2‐adrenoceptor agonists: current and future direction ⬇️

scientific article published on May 1, 2011

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