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List of works by Carsten Hopf

4-Phenyl-α-cyanocinnamic acid amide: screening for a negative ion matrix for MALDI-MS imaging of multiple lipid classes.

scientific article

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

scientific article

A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation

scientific article

Affinity profiling of the cellular kinome for the nucleotide cofactors ATP, ADP, and GTP.

scientific article published on 7 January 2013

Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis

scientific article

Alzheimer's-Causing Mutations Shift Aβ Length by Destabilizing γ-Secretase-Aβn Interactions

scientific article

Calcium-dependent maintenance of agrin-induced postsynaptic specializations.

scientific article published in January 2003

Chemical and pathway proteomics: powerful tools for oncology drug discovery and personalized health care.

scientific article published on August 2008

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

scientific article

Chemoproteomics reveals time-dependent binding of histone deacetylase inhibitors to endogenous repressor complexes

scientific article published on 6 June 2014

Chronic treatment with a novel γ-secretase modulator, JNJ-40418677, inhibits amyloid plaque formation in a mouse model of Alzheimer's disease.

scientific article

Computational Analysis of Alzheimer Amyloid Plaque Composition in 2D- and Elastically Reconstructed 3D-MALDI MS Images

scientific article published on 14 October 2020

DMSO-enhanced MALDI MS imaging with normalization against a deuterated standard for relative quantification of dasatinib in serial mouse pharmacology studies.

scientific article

Determination of kinase inhibitor potencies in cell extracts by competition binding assays and isobaric mass tags

scientific article published in January 2012

Dimerization of the muscle-specific kinase induces tyrosine phosphorylation of acetylcholine receptors and their aggregation on the surface of myotubes

scientific article published on 01 March 1998

Direct Automated MALDI Mass Spectrometry Analysis of Cellular Transporter Function: Inhibition of OATP2B1 Uptake by 294 Drugs

scientific article published on 12 August 2020

Discovery of a Highly Selective Tankyrase Inhibitor Displaying Growth Inhibition Effects against a Diverse Range of Tumor Derived Cell Lines.

scientific article

Emergence of whole-cell MALDI-MS biotyping for high-throughput bioanalysis of mammalian cells?

scientific article

Formation of postsynaptic-like membranes during differentiation of embryonic stem cells in vitro.

scientific article published in March 1998

Fourier Transform Infrared Microscopy Enables Guidance of Automated Mass Spectrometry Imaging to Predefined Tissue Morphologies.

scientific article published on 10 January 2018

Heparin inhibits acetylcholine receptor aggregation at two distinct steps in the agrin-induced pathway.

scientific article published on June 1997

Identification of serum proteins bound to industrial nanomaterials

scientific article

Imaging of complex sulfatides SM3 and SB1a in mouse kidney using MALDI-TOF/TOF mass spectrometry.

scientific article

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

scientific article

Inhibition of Rho-Associated Kinase 1/2 Attenuates Tumor Growth in Murine Gastric Cancer

scientific article published on August 2016

Label-free in situ monitoring of histone deacetylase drug target engagement by matrix-assisted laser desorption ionization-mass spectrometry biotyping and imaging.

scientific article

Mapping protein complexes using covalently linked antibodies and isobaric mass tags

scientific article published on 01 January 2014

Molecular imaging of brain localization of liposomes in mice using MALDI mass spectrometry.

scientific article

Monitoring CHO cell cultures: cell stress and early apoptosis assessment by mass spectrometry

scientific article

Murine Sialidase Neu3 facilitates GM2 degradation and bypass in mouse model of Tay-Sachs disease

scientific article published on 30 September 2017

Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer

scientific article

Nitric oxide synthase (NOS-1) coclustered with agrin-induced AChR-specializations on cultured skeletal myotubes.

scientific article published on September 2000

Optimized chemical proteomics assay for kinase inhibitor profiling.

scientific article

Pathway proteomics and chemical proteomics team up in drug discovery.

scientific article published on January 2007

Personalized monitoring of therapeutic salicylic acid in dried blood spots using a three-layer setup and desorption electrospray ionization mass spectrometry.

scientific article

Protein co-membership and biochemical affinity purifications

scientific article published on 01 January 2006

Purification, pharmacological modulation, and biochemical characterization of interactors of endogenous human gamma-secretase

scientific article

Quantitative characterization of tissue globotetraosylceramides in a rat model of polycystic kidney disease by PrimaDrop sample preparation and indirect high-performance thin layer chromatography-matrix-assisted laser desorption/ionization-time-of-f

scientific article

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

scientific article

Quantitative imaging mass spectrometry of renal sulfatides: validation by classical mass spectrometric methods

scientific article

Recent developments of novel matrices and on-tissue chemical derivatization reagents for MALDI-MSI

scientific article published on 19 November 2020

Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction.

scientific article

Scores for standardization of on-tissue digestion of formalin-fixed paraffin-embedded tissue in MALDI-MS imaging

scientific article published on 3 September 2016

Sensitive, robust and automated protein analysis of cell differentiation and of primary human blood cells by intact cell MALDI mass spectrometry biotyping ⬇️

scientific article published on September 6, 2012

Spatial Omics Imaging of Fresh-Frozen Tissue and Routine FFPE Histopathology of a Single Cancer Needle Core Biopsy: A Freezing Device and Multimodal Workflow

scientific article published in 2023

Spatial distribution of endogenous tissue protease activity in gastric carcinoma mapped by MALDI mass spectrometry imaging

scientific article published on 07 October 2018

Spatially resolved mass spectrometry analysis of amyloid plaque-associated lipids

scientific article published on 13 October 2020

Standardized processing of MALDI imaging raw data for enhancement of weak analyte signals in mouse models of gastric cancer and Alzheimer's disease.

scientific article

Structure-performance relationships of phenyl cinnamic acid derivatives as MALDI-MS matrices for sulfatide detection

scientific article

Studying epigenetic complexes and their inhibitors with the proteomics toolbox

scientific article

Sulfatides are required for renal adaptation to chronic metabolic acidosis

scientific article published on 28 May 2013

The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas.

scientific article published on 15 November 2016

Therapeutic drug monitoring in dried blood spots using liquid microjunction surface sampling and high resolution mass spectrometry

scientific article published on 13 January 2016

Tyrosine phosphorylation of the muscle-specific kinase is exclusively induced by acetylcholine receptor-aggregating agrin fragments.

scientific article published on April 1998

mGluR1/5-dependent long-term depression requires the regulated ectodomain cleavage of neuronal pentraxin NPR by TACE.

scientific article published on March 2008

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